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Cynthia E. Hawkins
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Journal Articles

Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade

Melissa A. Galati, Karl P. Hodel, Miki S. Gams, Sumedha Sudhaman, Taylor Bridge, Walter J. Zahurancik, Nathan A. Ungerleider, Vivian S. Park, Ayse B. Ercan, Lazar Joksimovic, Iram Siddiqui, Robert Siddaway, Melissa Edwards, Richard de Borja, Dana Elshaer, Jiil Chung, Victoria J. Forster, Nuno M. Nunes, Melyssa Aronson, Xia Wang, Jagadeesh Ramdas, Andrea Seeley, Tomasz Sarosiek, Gavin P. Dunn, Jonathan N. Byrd, Oz Mordechai, Carol Durno, Alberto Martin, Adam Shlien, Eric Bouffet, Zucai Suo, James G. Jackson, Cynthia E. Hawkins, Cynthia J. Guidos, Zachary F. Pursell, Uri Tabori
Journal: Cancer Research
Cancer Res (2020) 80 (24): 5606–5618.
https://doi.org/10.1158/0008-5472.CAN-20-0624
Published: 15 December 2020
View article titled, Cancers from Novel <em>Pole</em>-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade
Open the PDF for Cancers from Novel <em>Pole</em>-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade in another window
Includes: Supplementary data
Journal Articles

A Metastatic Mouse Model Identifies Genes That Regulate Neuroblastoma Metastasis

Bo Kyung A. Seong, Kelly E. Fathers, Robin Hallett, Christina K. Yung, Lincoln D. Stein, Samar Mouaaz, Lynn Kee, Cynthia E. Hawkins, Meredith S. Irwin, David R. Kaplan
Journal: Cancer Research
Cancer Res (2017) 77 (3): 696–706.
https://doi.org/10.1158/0008-5472.CAN-16-1502
Published: 31 January 2017
View article titled, A Metastatic Mouse Model Identifies Genes That Regulate Neuroblastoma Metastasis
Open the PDF for A Metastatic Mouse Model Identifies Genes That Regulate Neuroblastoma Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract LB-179: Integrated (epi)genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors

Jonathon Torchia, Shengrui Feng, King Ching Ho, Louis Letourneau, Daniel Picard, Tiffany S. Chan, Alexandre Vasiljevic, Dong Anh Khuong Quang, Brian Golbourn, Dalia Barsyte-Lovejoy, Constanze Zeller, Patrick Sin-Chan, Natalia R. Agamez, Mei Lu, Lucie Lafay-Cousin, Joseph D. Norman, Maryam Fouladi, Lindsey M. Hoffman, Stefan Rutkowski, Torsten Pietsch, Alexander R. Judkins, Eric Bouffet, James T. Rutka, Cynthia E. Hawkins, Cheryl H. Arrowsmith, Daniel De Carvalho, Nada Jabado, Annie Huang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-179.
https://doi.org/10.1158/1538-7445.AM2016-LB-179
Published: 15 July 2016
View article titled, Abstract LB-179: Integrated (epi)genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors
Journal Articles

Abstract 1432: The heterogeneous genomic landscape of posterior fossa ependymoma

Hendrik Witt, Stephen C. Mack, Sebastian Bender, Marina Ryzhova, Sill Martin, Ruth Isserlin, David T. W. Jones, Paul A. Northcott, Milde Till, Marc Remke, Axel Benner, Thomas Hielscher, Nalin Gupta, Livia Garcia, William A. Weiss, Kelsey Betrand, Timothy van Meter, Andreas von Deimling, Stefan Rutkowski, Torsten Pietsch, Andreas E. Kulozik, Yoon-Jae Cho, Uri Tabori, Cynthia E. Hawkins, Olaf Witt, Gary D. Bader, James T. Rutka, Peter Lichter, Andrey Korshunov, Michael D. Taylor, Stefan M. Pfister
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1432.
https://doi.org/10.1158/1538-7445.AM2012-1432
Published: 15 April 2012
View article titled, Abstract 1432: The heterogeneous genomic landscape of posterior fossa ependymoma
Journal Articles

Abstract 3109: Myc confers aggressive medulloblastoma phenotypes by regulating cell migration and adhesion genes

Daniel J. Picard, Limei Zhou, Yaqi Hu, Meihua Li, David Shih, Duncan Stearns, Susan Cohn, Cynthia E. Hawkins, James T. Rutka, Michal D. Taylor, Annie Huang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3109.
https://doi.org/10.1158/1538-7445.AM10-3109
Published: 15 April 2010
View article titled, Abstract 3109: Myc confers aggressive medulloblastoma phenotypes by regulating cell migration and adhesion genes
Journal Articles

Abstract 4355: The C19MC miRNA polycistron are frequent targets of gene amplification in aggressive primitive neuroectodermal brain tumors and encode oncogenic miRNAs that inhibit normal neural stem cell differentiation

Meihua Li, Kyle Lee, Yuntao Lu, Ian Clarke, David Shih, Tim Van Meter, Limei Zhou, Daniel Picard, Piergiorgio Modena, Scott Pomeroy, Ching C. Lau, Micheal D. Taylor, Eric Bouffet, James T. Rutka, Amar Gajjar, Peter B. Dirks, Cynthia E. Hawkins, Annie Huang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4355.
https://doi.org/10.1158/1538-7445.AM10-4355
Published: 15 April 2010
View article titled, Abstract 4355: The C19MC miRNA polycistron are frequent targets of gene amplification in aggressive primitive neuroectodermal brain tumors and encode oncogenic miRNAs that inhibit normal neural stem cell differentiation
Journal Articles

Identification of a Novel c-Myc Protein Interactor, JPO2, with Transforming Activity in Medulloblastoma Cells

Annie Huang, Cynthia S.W. Ho, Romina Ponzielli, Dalia Barsyte-Lovejoy, Eric Bouffet, Daniel Picard, Cynthia E. Hawkins, Linda Z. Penn
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5607–5619.
https://doi.org/10.1158/0008-5472.CAN-05-0500
Published: 01 July 2005
View article titled, Identification of a Novel c-Myc Protein Interactor, JPO2, with Transforming Activity in Medulloblastoma Cells
Open the PDF for Identification of a Novel c-Myc Protein Interactor, JPO2, with Transforming Activity in Medulloblastoma Cells in another window
Includes: Supplementary data