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Curtis A. Clark
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Journal Articles

CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade

Justin M. Drerup, Yilun Deng, Sri Lakshmi Pandeswara, Álvaro S. Padrón, Ryan M. Reyes, Xinyue Zhang, Jenny Mendez, Aijie Liu, Curtis A. Clark, Wanjiao Chen, José R. Conejo-Garcia, Vincent Hurez, Harshita Gupta, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2020) 80 (22): 5063–5075.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-0002
Published: 13 November 2020
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Includes: Supplementary data
Journal Articles

Abstract 3696: Tumor-intrinsic PD-L1 alters tumor chemokines, NK cell trafficking and function, and renders distant PD-L1 null tumors responsive to αPD-L1

Curtis A. Clark, Harshita B. Gupta, Alvaro Padron, Deyi Zhang, Vincent Hurez, Mary Jo Turk, Rong Li, Tyler Curiel
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3696.
DOI: https://doi.org/10.1158/1538-7445.AM2017-3696
Published: 01 July 2017
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Journal Articles

Abstract 1608: CD122-selective IL-2/anti-IL-2 complexes reduce regulatory T cell function and promote CD8+ T cell polyfunctionality for durable ovarian cancer immunotherapy

Justin M. Drerup, Sri Lakshmi Pandeswara, Aijie Liu, Curtis A. Clark, Alvaro S. Padron, Wanjiao Chen, Vincent Hurez, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1608.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1608
Published: 01 July 2017
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Journal Articles

Abstract 5649: Cell-intrinsic PD-L1 directs tumor initiating cell fate and rapamycin and interferon-γ response

Harshita B. Gupta, Curtis A. Clark, Bin Yuan, Gangadhara Sareddy, Srilakshmi Pandeswara, Alvaro S. Padron, Vincent Hurez, Jose-Conejo Garcia, Ratna Vadlamudi, Rong Li, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5649.
DOI: https://doi.org/10.1158/1538-7445.AM2017-5649
Published: 01 July 2017
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Journal Articles

Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma

Curtis A. Clark, Harshita B. Gupta, Gangadhara Sareddy, Srilakshmi Pandeswara, Shunhua Lao, Bin Yuan, Justin M. Drerup, Alvaro Padron, José Conejo-Garcia, Kruthi Murthy, Yang Liu, Mary Jo Turk, Kathrin Thedieck, Vincent Hurez, Rong Li, Ratna Vadlamudi, Tyler J. Curiel
Journal: Cancer Research
Cancer Res (2016) 76 (23): 6964–6974.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-0258
Published: 30 November 2016
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Includes: Supplementary data