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Cristina Guarducci
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Journal Articles

Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer

Open Access
Francisco Hermida-Prado, Yingtian Xie, Shira Sherman, Zsuzsanna Nagy, Douglas Russo, Tara Akhshi, Zhengtao Chu, Avery Feit, Marco Campisi, Minyue Chen, Agostina Nardone, Cristina Guarducci, Klothilda Lim, Alba Font-Tello, Irene Lee, Juana García-Pedrero, Israel Cañadas, Judith Agudo, Ying Huang, Tal Sella, Qingchun Jin, Nabihah Tayob, Elizabeth A. Mittendorf, Sara M. Tolaney, Xintao Qiu, Henry Long, William F. Symmans, Jia-Ren Lin, Sandro Santagata, Isabelle Bedrosian, Denise A. Yardley, Ingrid A. Mayer, Edward T. Richardson, Giacomo Oliveira, Catherine J. Wu, Eugene F. Schuster, Mitch Dowsett, Alana L. Welm, David Barbie, Otto Metzger, Rinath Jeselsohn
Journal: Cancer Research
Cancer Res (2023) 83 (19): 3284–3304.
https://doi.org/10.1158/0008-5472.CAN-23-1711
Published: 02 October 2023
View articletitled, Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer
Open the PDF for Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract P5-02-17: Prognostic and predictive role of RBsig and CCNE1/RB1 gene-expression signatures in patients with advanced breast cancer treated with palbociclib in combination with endocrine therapy in the PALOMA-2 and 3 trials

Free
Luca Malorni, Matteo Benelli, Yuan Liu, Shibing Deng, Zhe Zhang, Cristina Guarducci, Angela Leo, Agostina Nardone, Francesca Galardi, Emanuela Risi, Erica Moretti, Dario Romagnoli, Chiara Biagioni, Marta Paoli, Laura Biganzoli, Ilenia Migliaccio
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-02-17.
https://doi.org/10.1158/1538-7445.SABCS22-P5-02-17
Published: 01 March 2023
View articletitled, Abstract P5-02-17: Prognostic and predictive role of RBsig and CCNE1/RB1 gene-expression signatures in patients with advanced breast cancer treated with palbociclib in combination with endocrine therapy in the PALOMA-2 and 3 trials
Journal Articles

Abstract GS3-07: GS3-07 Clonal evolution and mechanisms of acquired resistance to CDK4/6 inhibitors in ER-wild type and ER-mutant breast cancer

Free
Cristina Guarducci, Simona Cristea, Avery Feit, Sergey Naumenko, Agostina Nardone, Wen Ma, Douglas Russo, Gabriella Cohen Feit, Ariel Feiglin, Francisco Hermida-Prado, Shira Sherman, Myles Brown, Franziska Michor, Rinath Jeselsohn
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): GS3-07.
https://doi.org/10.1158/1538-7445.SABCS22-GS3-07
Published: 01 March 2023
View articletitled, Abstract GS3-07: GS3-07 Clonal evolution and mechanisms of acquired resistance to CDK4/6 inhibitors in ER-wild type and ER-mutant breast cancer
Journal Articles

A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer

Available to Purchase
Agostina Nardone, Xintao Qiu, Sandor Spisak, Zsuzsanna Nagy, Ariel Feiglin, Avery Feit, Gabriela Cohen Feit, Yingtian Xie, Alba Font-Tello, Cristina Guarducci, Francisco Hermida-Prado, Sudeepa Syamala, Klothilda Lim, Miguel Munoz Gomez, Matthew Pun, MacIntosh Cornwell, Weihan Liu, Aysegul Ors, Hisham Mohammed, Paloma Cejas, Jane B. Brock, Matthew L. Freedman, Eric P. Winer, Xiaoyong Fu, Rachel Schiff, Henry W. Long, Otto Metzger Filho, Rinath Jeselsohn
Journal: Cancer Research
Cancer Res (2022) 82 (20): 3673–3686.
https://doi.org/10.1158/0008-5472.CAN-21-3186
Published: 17 October 2022
View articletitled, A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer
Open the PDF for A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5802: Isotopic tracing reveals distinct metabolic changes with palbociclib or abemaciclib treatment & resistance in breast cancer cell lines

Free
Chandrashekhar Honrao, Kanchan Sonkar, Cristina Guarducci, Agostina Nardone, Wen Ma, Srihari Raghavendra Rao, Chen Dong, Leo Rodrigues, Rinath Jeselsohn, Elizabeth O'Day
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5802.
https://doi.org/10.1158/1538-7445.AM2022-5802
Published: 15 June 2022
View articletitled, Abstract 5802: Isotopic tracing reveals distinct metabolic changes with palbociclib or abemaciclib treatment & resistance in breast cancer cell lines
Journal Articles

Abstract B16: Mathematical modeling identifies optimum palbociclib dosing schedules for the treatment of estrogen receptor-positive (ER+) breast cancer patients

Free
Shayna Stein, Agostina Nardone, Weihan Liu, Gabriella Cohen, Cristina Guarducci, Myles Brown, Rinath Jeselsohn, Franziska Michor
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): B16.
https://doi.org/10.1158/1538-7445.CAMODELS2020-B16
Published: 02 June 2020
View articletitled, Abstract B16: Mathematical modeling identifies optimum palbociclib dosing schedules for the treatment of estrogen receptor-positive (ER+) breast cancer patients
Journal Articles

Abstract S1-01: TransCONFIRM: The correlative analysis of breast tumors from patients with advanced hormone receptor positive disease identifies a genetic signature associated with decreased benefit from single agent fulvestrant

Free
Rinath M Jeselsohn, William T Barry, Jin Zhao, Gilles Buchwalter, Cristina Guarducci, Ilenia Migliaccio, Chiara Biagioni, Martina Bonechi, Naomi Laing, Yuri Rukazenkov, Eric P Winer, Myles Brown, Angelo Di Leo, Luca Malorni
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): S1-01.
https://doi.org/10.1158/1538-7445.SABCS14-S1-01
Published: 01 May 2015
View articletitled, Abstract S1-01: TransCONFIRM: The correlative analysis of breast tumors from patients with advanced hormone receptor positive disease identifies a genetic signature associated with decreased benefit from single agent fulvestrant