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Corey W. Speers
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Journal Articles

Abstract 1829: Potentiating antitumoral type 1 interferon immune signaling in triple-negative breast cancer (TNBC) via combination treatment of Aurora kinase B (AURKB) inhibition and radiation therapy

Kassidy M. Jungles, Caroline R. Bishop, Cydnee Wilson, Meilan Liu, Corey W. Speers, Lori Pierce, James Rae
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1829.
https://doi.org/10.1158/1538-7445.AM2025-1829
Published: 21 April 2025
View articletitled, Abstract 1829: Potentiating antitumoral type 1 interferon immune signaling in triple-negative breast cancer (TNBC) via combination treatment of Aurora kinase B (AURKB) inhibition and radiation therapy
Journal Articles

Abstract 708: Targeting aurora kinase B (AURKB) as a radiosensitizing strategy in syngeneic models of triple negative breast cancer (TNBC)

Kassidy M. Jungles, Zhuwen Wang, Caroline Bishop, Cydnee Wilson, Meilan Liu, Jadyn James, Michael Green, James M. Rae, Corey W. Speers, Lori J. Pierce
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 708.
https://doi.org/10.1158/1538-7445.AM2024-708
Published: 22 March 2024
View articletitled, Abstract 708: Targeting aurora kinase B (AURKB) as a radiosensitizing strategy in syngeneic models of triple negative breast cancer (TNBC)
Journal Articles

Abstract 2401: Molecular mechanisms of intrinsic radioresistance in breast cancer

Breanna N. McBean, Anna R. Michmerhuizen, Kari Wilder-Romans, Benjamin C. Chandler, Lynn M. Lerner, Connor Ward, Meilan Liu, Alan P. Boyle, Corey W. Speers
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2401.
https://doi.org/10.1158/1538-7445.AM2023-2401
Published: 04 April 2023
View articletitled, Abstract 2401: Molecular mechanisms of intrinsic radioresistance in breast cancer
Journal Articles

Abstract 5471: Integrating tumor-intrinsic and immunological factors to identify immunogenic breast cancers from a low-risk cohort; results from the randomized SweBCG91RT trial

Axel Stenmark Tullberg, Martin Sjöström, Emma Niméus, Fredrik Killander, Laura Chang, Felix Y. Feng, Corey W. Speers, Lori J. Pierce, Anokó Kovács, Dan Lundstedt, Erik Holmberg, Per Karlsson
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5471.
https://doi.org/10.1158/1538-7445.AM2023-5471
Published: 04 April 2023
View articletitled, Abstract 5471: Integrating tumor-intrinsic and immunological factors to identify immunogenic breast cancers from a low-risk cohort; results from the randomized SweBCG91RT trial
Journal Articles

Abstract P4-02-12: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in early-stage invasive breast cancer patients of the Scottish Conservation Trial

Karen J. Taylor, John MS Bartlett, John Bennett, S. Laura Chang, Bradley Arrick, Frederick Baehner, Joseph F. Loane, Tammy Piper, Elizabeth Mallon, Joanna Dunlop, Wilma J. Jack, Jacqueline Caldwell, Ian Kunkler, Linda J. Williams, Corey W. Speers, Felix Y. Feng, Lori Pierce, David A. Cameron
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-02-12.
https://doi.org/10.1158/1538-7445.SABCS22-P4-02-12
Published: 01 March 2023
View articletitled, Abstract P4-02-12: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in early-stage invasive breast cancer patients of the Scottish Conservation Trial
Journal Articles

Abstract GS4-03: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in a meta-analysis of three randomized controlled trials of breast conserving surgery +/- radiotherapy

Per Karlsson, Anthony Fyles, S. Laura Chang, Bradley Arrick, Frederick Baehner, Per Malmström, Mårten Fernö, Erik Holmberg, Martin Sjöström, Fei-Fei Liu, David A. Cameron, Linda J. Williams, John MS Bartlett, Joanna Dunlop, Jacqueline Caldwell, Joseph F. Loane, Elizabeth Mallon, Tammy Piper, Wilma J. Jack, Ian Kunkler, Felix Y. Feng, Corey W. Speers, Lori Pierce, John Bennett, Karen J. Taylor
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): GS4-03.
https://doi.org/10.1158/1538-7445.SABCS22-GS4-03
Published: 01 March 2023
View articletitled, Abstract GS4-03: Validation of Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) in a meta-analysis of three randomized controlled trials of breast conserving surgery +/- radiotherapy
Journal Articles

Abstract P1-09-05: Effect of Wire vs Magnetic Seed Localization on Lumpectomy Cavity Size

Michael Dykstra, Jessica Thompson, Jessica Aldous, Shannon Jiang, Tasha Hughes, James Hayman, Aleksandar Dragovic, Jennifer Shah, Alfred Chang, Corey W. Speers, Michael Sabel, Lesly Dossett, Matthew Schipper, Reshma Jagsi
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P1-09-05.
https://doi.org/10.1158/1538-7445.SABCS22-P1-09-05
Published: 01 March 2023
View articletitled, Abstract P1-09-05: Effect of Wire vs Magnetic Seed Localization on Lumpectomy Cavity Size
Journal Articles

Abstract 3307: Multiomics analysis to uncover the mechanism of radiosensitization of AR-positive triple negative breast cancers with AR inhibition

Anna R. Michmerhuizen, Andrea M. Pesch, Benjamin C. Chandler, Lynn M. Lerner, Connor Ward, Leah Moubadder, Stephanie The, Breanna McBean, Caleb Cheng, Lori J. Pierce, Corey W. Speers
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3307.
https://doi.org/10.1158/1538-7445.AM2022-3307
Published: 15 June 2022
View articletitled, Abstract 3307: Multiomics analysis to uncover the mechanism of radiosensitization of AR-positive triple negative breast cancers with AR inhibition
Journal Articles

Abstract 216: Expression of DNA damage response proteins modifies the efficacy of CDK4/6 inhibitor-mediated radiosensitization in breast cancer models

Kassidy M. Jungles, Andrea M. Pesch, Nicole Hirsh, Anna R. Michmerhuizen, Kari Wilder-Romans, Benjamin C. Chandler, Meilan Liu, Lynn Lerner, Lori J. Pierce, James M. Rae, Corey W. Speers
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 216.
https://doi.org/10.1158/1538-7445.AM2022-216
Published: 15 June 2022
View articletitled, Abstract 216: Expression of DNA damage response proteins modifies the efficacy of CDK4/6 inhibitor-mediated radiosensitization in breast cancer models
Journal Articles

Abstract 2697: Inhibition of estrogen receptor signaling as a strategy for radiosensitization of ER+ breast cancers

Anna R. Michmerhuizen, Lynn M. Lerner, Andrea M. Pesch, Connor Ward, Rachel Schwartz, Kari Wilder-Romans, Meilan Liu, Charles Nino, Kassidy Jungles, Ruth Azaria, Alexa Jelley, Nicole Zambrana Garcia, Alexis Harold, Amanda Zhang, Bryan Wharram, Daniel F. Hayes, James M. Rae, Lori J. Pierce, Corey W. Speers
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2697.
https://doi.org/10.1158/1538-7445.AM2022-2697
Published: 15 June 2022
View articletitled, Abstract 2697: Inhibition of estrogen receptor signaling as a strategy for radiosensitization of ER+ breast cancers
Journal Articles

Abstract 215: MDM2 inhibition as a non-hormone dependent radiosensitizing strategy in p53 wild-type breast cancer models

Charles A. Nino, Cassandra L. Ritter, Andrea M. Pesch, Anna R. Michmerhuizen, Benjamin C. Chandler, Yashmeet Kaur, Maria Fields, Lynn Lerner, Lori J. Pierce, Corey W. Speers
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 215.
https://doi.org/10.1158/1538-7445.AM2022-215
Published: 15 June 2022
View articletitled, Abstract 215: MDM2 inhibition as a non-hormone dependent radiosensitizing strategy in p53 wild-type breast cancer models
Journal Articles

Abstract PD9-06: Evaluation of the predicted sensitivity to endocrine therapy (SET2,3 index) and the 21-gene Breast Recurrence Score® assay in node-positive postmenopausal breast cancer: Results from an analysis in the SWOG S8814 trial

Corey W. Speers, W. Fraser Symmans, William E. Barlow, Alex Trevarton, Stephanie The, Lili Du, James M. Rae, Steven Shak, Frederick L. Baehner, Priyanka Sharma, Lajos Pusztai, Gabriel N. Hortobagyi, Daneil F Hayes, Kathy S. Albain, Andrew Godwin, Alastair Thompson
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD9-06.
https://doi.org/10.1158/1538-7445.SABCS21-PD9-06
Published: 15 February 2022
View articletitled, Abstract PD9-06: Evaluation of the predicted sensitivity to endocrine therapy (SET2,3 index) and the 21-gene Breast Recurrence Score® assay in node-positive postmenopausal breast cancer: Results from an analysis in the SWOG S8814 trial
Journal Articles

Abstract P4-02-04: Endocrine therapy treatment radiosensitizes estrogen receptor-positive breast cancers

Anna R Michmerhuizen, Lynn Lerner, Andrea M Pesch, Connor Ward, Rachel Schwartz, Kari Wilder-Romans, Meilan Liu, Bryan Wharram, Alexis Harold, Ruth Azaria, Nicole Zambrana Garcia, Daniel F Hayes, James M Rae, Lori J Pierce, Corey W Speers
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P4-02-04.
https://doi.org/10.1158/1538-7445.SABCS21-P4-02-04
Published: 15 February 2022
View articletitled, Abstract P4-02-04: Endocrine therapy treatment radiosensitizes estrogen receptor-positive breast cancers
Journal Articles

Abstract 1386: The role of MDM2 inhibition in the radiosensitization of ER+ breast cancers

Cassandra Lynne Ritter, Benjamin C. Chandler, Andrea M. Pesch, Anna R. Michmerhuizen, Nicole Hirsh, Tanner Ward, Amanda Zhang, Mattia Cremona, Lori J. Pierce, Bryan Hennessy, Corey W. Speers
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1386.
https://doi.org/10.1158/1538-7445.AM2021-1386
Published: 01 July 2021
View articletitled, Abstract 1386: The role of MDM2 inhibition in the radiosensitization of ER+ breast cancers
Journal Articles

Abstract 1943: Radiosensitization of PIK3CA wild type triple negative breast cancers with Bcl-family inhibition

Andrea M. Pesch, Benjamin C. Chandler, Anna R. Michmerhuizen, Nicole Hirsh, Kari Wilder-Romans, Meilan Liu, Tanner Ward, Dana Messinger, Charles Nino, Cassandra Ritter, James M. Rae, Corey W. Speers
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1943.
https://doi.org/10.1158/1538-7445.AM2021-1943
Published: 01 July 2021
View articletitled, Abstract 1943: Radiosensitization of PIK3CA wild type triple negative breast cancers with Bcl-family inhibition
Journal Articles

Abstract 1952: CDK4/6 inhibition radiosensitizes RB1 wild type triple negative breast cancers through impaired homologous recombination

Andrea M. Pesch, Nicole Hirsh, Anna R. Michmerhuizen, Benjamin C. Chandler, Kari Wilder-Romans, Meilan Liu, Lori J. Pierce, James M. Rae, Corey W. Speers
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1952.
https://doi.org/10.1158/1538-7445.AM2021-1952
Published: 01 July 2021
View articletitled, Abstract 1952: CDK4/6 inhibition radiosensitizes RB1 wild type triple negative breast cancers through impaired homologous recombination
Journal Articles

Abstract 737: Estrogen receptor inhibition with tamoxifen mediates radiosensitization of ER+ breast cancer models

Anna R. Michmerhuizen, Andrea M. Pesch, Rachel Schwartz, Kari Wilder-Romans, Meilan Liu, Ruth Azaria, Alexa Jelley, Lori J. Pierce, Corey W. Speers
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 737.
https://doi.org/10.1158/1538-7445.AM2021-737
Published: 01 July 2021
View articletitled, Abstract 737: Estrogen receptor inhibition with tamoxifen mediates radiosensitization of ER+ breast cancer models
Journal Articles

Abstract 6270: A radiosensitizer screen identifies a novel role for MDM2 inhibition in the radiosensitization of ER+ breast cancers in a p53 dependent manner

Cassandra L. Ritter, Benjamin C. Chandler, Andrea M. Pesch, Anna R. Michmerhuizen, Nicole Hirsh, Amanda Zhang, Tanner Ward, Mattia Cremona, Bryan Hennessy, Lori J. Pierce, Corey W. Speers
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6270.
https://doi.org/10.1158/1538-7445.AM2020-6270
Published: 15 August 2020
View articletitled, Abstract 6270: A radiosensitizer screen identifies a novel role for MDM2 inhibition in the radiosensitization of ER+ breast cancers in a p53 dependent manner
Journal Articles

Abstract 6280: CDK4/6 inhibitor-mediatated radiosensitization of estrogen receptor positive breast cancer

Andrea M. Pesch, Nicole Hirsh, Benjamin C. Chandler, Anna R. Michmerhuizen, Cassandra L. Ritter, Marlie Androsiglio, Kari Wilder-Romans, Meilan Liu, Christina L. Gersch, Jose M. Larios, James M. Rae, Corey W. Speers
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6280.
https://doi.org/10.1158/1538-7445.AM2020-6280
Published: 15 August 2020
View articletitled, Abstract 6280: CDK4/6 inhibitor-mediatated radiosensitization of estrogen receptor positive breast cancer
Journal Articles

Abstract 4766: Transcriptomic profiling reveals a potential role for JAK/STAT inhibition in CDK4/6 inhibitor-resistant, ER+ breast cancers

Andrea M. Pesch, Thomas L. Gonzalez, Benjamin C. Chandler, Siqi Sun, Christina L. Gersch, José M. Larios, Wadie S. David, Corey W. Speers, James M. Rae
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4766.
https://doi.org/10.1158/1538-7445.AM2019-4766
Published: 01 July 2019
View articletitled, Abstract 4766: Transcriptomic profiling reveals a potential role for JAK/STAT inhibition in CDK4/6 inhibitor-resistant, ER+ breast cancers