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Journal Articles

Abstract 3072: Novel approach to target trastuzumab resistant, HER2+ breast cancer: Activation of PKCdelta

Maria Mejia, Debra Wyatt, Mitchell F. Denning, Kelvin Billingsley, Clodia Osipo

Cancer Res (2025) 85 (8_Supplement_1): 3072.

https://doi.org/10.1158/1538-7445.AM2025-3072

Published: 21 April 2025

View articletitled, Abstract 3072: Novel approach to target trastuzumab resistant, HER2+ breast cancer: Activation of PKCdelta

Journal Articles

Abstract PO4-27-12: Increasing DAXX as a Novel Approach to Inhibit Breast Cancer Stem Cells and Estrogen Receptor-positive Tumor Recurrence

Clodia Osipo, Debra Wyatt, Kathy Albain

Cancer Res (2024) 84 (9_Supplement): PO4-27-12.

https://doi.org/10.1158/1538-7445.SABCS23-PO4-27-12

Published: 02 May 2024

View articletitled, Abstract PO4-27-12: Increasing DAXX as a Novel Approach to Inhibit Breast Cancer Stem Cells and Estrogen Receptor-positive Tumor Recurrence

Journal Articles

Abstract LB230: Critical role for DAXX in triple negative breast cancer

Clodia Osipo, Debra Wyatt

Cancer Res (2023) 83 (8_Supplement): LB230.

https://doi.org/10.1158/1538-7445.AM2023-LB230

Published: 14 April 2023

View articletitled, Abstract LB230: Critical role for DAXX in triple negative breast cancer

Journal Articles

Abstract P3-11-01: Increasing DAXX Expression in ER+ Breast Cancer Cells to Overcome Endocrine Therapy Resistance

Clodia Osipo, Kathy S. Albain, Daniel Peiffer, Debra Wyatt

Cancer Res (2023) 83 (5_Supplement): P3-11-01.

https://doi.org/10.1158/1538-7445.SABCS22-P3-11-01

Published: 01 March 2023

View articletitled, Abstract P3-11-01: Increasing DAXX Expression in ER+ Breast Cancer Cells to Overcome Endocrine Therapy Resistance

Journal Articles

Abstract P5-12-10: A commensal’s exopolysaccharide inhibits breast cancer proliferation in vitro but promotes tumor growth in vivo

Mai Rachel Nguyen, Katherine L Knight, Clodia Osipo

Cancer Res (2022) 82 (4_Supplement): P5-12-10.

https://doi.org/10.1158/1538-7445.SABCS21-P5-12-10

Published: 15 February 2022

View articletitled, Abstract P5-12-10: A commensal’s exopolysaccharide inhibits breast cancer proliferation in vitro but promotes tumor growth in vivo

Journal Articles

Abstract P3-05-03: KMT2D as a novel therapeutic target for HER2+ breast cancers

Emily Ma, Andrei Zlobin, Debra Wyatt, Jeffrey Ng, Andrew Dingwall, Clodia Osipo

Cancer Res (2022) 82 (4_Supplement): P3-05-03.

https://doi.org/10.1158/1538-7445.SABCS21-P3-05-03

Published: 15 February 2022

View articletitled, Abstract P3-05-03: KMT2D as a novel therapeutic target for HER2+ breast cancers

Journal Articles

Abstract P1-08-22: The role of DAXX as a critical growth regulator of triple negative breast cancer

Clodia Osipo, Debra Wyatt, Michelle Fernandez, Daniel S Peiffer, Kathy S Albain

Cancer Res (2022) 82 (4_Supplement): P1-08-22.

https://doi.org/10.1158/1538-7445.SABCS21-P1-08-22

Published: 15 February 2022

View articletitled, Abstract P1-08-22: The role of DAXX as a critical growth regulator of triple negative breast cancer

Journal Articles

Abstract PS18-03: Differential gene expression in luminal-type invasive lobular carcinoma and invasive ductal carcinoma by MammaPrint risk stratification

Beth-Ann Lesnikoski, Jennifer A. Crozier, Gordan Srkalovic, Patricia Robinson, Clodia Osipo, Kaylan Banda, Heather M. Kling, Josien Haan, William Audeh, FLEX Investigators Group

Cancer Res (2021) 81 (4_Supplement): PS18-03.

https://doi.org/10.1158/1538-7445.SABCS20-PS18-03

Published: 15 February 2021

View articletitled, Abstract PS18-03: Differential gene expression in luminal-type invasive lobular carcinoma and invasive ductal carcinoma by MammaPrint risk stratification

Journal Articles

Abstract 6101: Exopolysaccharide secreted by Bacillus subtilis alters breast cancer cell growth and stemness

Mai Rachel Nguyen, Clodia Osipo, Katherine L. Knight

Cancer Res (2020) 80 (16_Supplement): 6101.

https://doi.org/10.1158/1538-7445.AM2020-6101

Published: 15 August 2020

View articletitled, Abstract 6101: Exopolysaccharide secreted by Bacillus subtilis alters breast cancer cell growth and stemness

Journal Articles

Abstract 1859: Elucidating the role of KMT2D as a novel therapeutic target for resistant HER2+ breast cancer

EMILY MA, Andrei Zlobin, Debra Wyatt, Jeffrey Ng, Andrew Dingwall, Clodia Osipo

Cancer Res (2020) 80 (16_Supplement): 1859.

https://doi.org/10.1158/1538-7445.AM2020-1859

Published: 15 August 2020

View articletitled, Abstract 1859: Elucidating the role of KMT2D as a novel therapeutic target for resistant HER2+ breast cancer

Journal Articles

DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor–Positive Breast Cancer Following Endocrine Therapy

Daniel S. Peiffer, Debra Wyatt, Andrei Zlobin, Ali Piracha, Jeffrey Ng, Andrew K. Dingwall, Kathy S. Albain, Clodia Osipo

Cancer Res (2019) 79 (19): 4965–4977.

https://doi.org/10.1158/0008-5472.CAN-19-1110

Published: 01 October 2019

View articletitled, DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor–Positive Breast Cancer Following Endocrine Therapy

Includes: Supplementary data

Journal Articles

Abstract 5845: Roles for MLL2/ KMT2D or MLL3/ KMT2C in HER+ breast cancer stem cells

Andrei Zlobin, Debra Wyatt, Mary Varsanik, Andrew Dingwall, Clodia Osipo

Cancer Res (2018) 78 (13_Supplement): 5845.

https://doi.org/10.1158/1538-7445.AM2018-5845

Published: 01 July 2018

View articletitled, Abstract 5845: Roles for MLL2/ KMT2D or MLL3/ KMT2C in HER+ breast cancer stem cells

Journal Articles

Abstract 1831: PKCδ as a novel target for HER2-positive, trastuzumab resistant breast cancer

Debra L. Wyatt, Andrei Zlobin, Emily Ma, Mitchell F. Denning, Clodia Osipo

Cancer Res (2018) 78 (13_Supplement): 1831.

https://doi.org/10.1158/1538-7445.AM2018-1831

Published: 01 July 2018

View articletitled, Abstract 1831: PKCδ as a novel target for HER2-positive, trastuzumab resistant breast cancer

Journal Articles

Abstract 1335: Deubiquitinase OTUD6B isoforms are important regulators of growth and proliferation

Maurizio Bocchetta, Clodia Osipo, Anna Sobol

Cancer Res (2017) 77 (13_Supplement): 1335.

https://doi.org/10.1158/1538-7445.AM2017-1335

Published: 01 July 2017

View articletitled, Abstract 1335: Deubiquitinase OTUD6B isoforms are important regulators of growth and proliferation

Journal Articles

Abstract 4769: Targeting HER2 enriches Jagged1 high cancer stem cells in breast cancer

Deep S. Shah, Debra Wyatt, Andrew Baker, Andrew Green, Aleksandra Filipovic, Lucio Miele, Clodia Osipo

Cancer Res (2017) 77 (13_Supplement): 4769.

https://doi.org/10.1158/1538-7445.AM2017-4769

Published: 01 July 2017

View articletitled, Abstract 4769: Targeting HER2 enriches Jagged1 high cancer stem cells in breast cancer

Journal Articles

Abstract 2124: Notch-1 mediated down regulation of PTEN in trastuzumab resistant HER2+ breast cancer

Andrew T. Baker, Kinnari Pandya, Clodia Osipo

Cancer Res (2016) 76 (14_Supplement): 2124.

https://doi.org/10.1158/1538-7445.AM2016-2124

Published: 15 July 2016

View articletitled, Abstract 2124: Notch-1 mediated down regulation of PTEN in trastuzumab resistant HER2+ breast cancer

Journal Articles

Abstract LB-121: DAXX is a novel Notch-1 gene target and biomarker of GSI-sensitivity in ER+ breast cancer

Andrei Zlobin, Debra Wyatt, Jeffrey C. Bloodworth, Susan Hilsenbeck, Suzanne Fuqua, Lucio Miele, Kathy S. Albain, Clodia Osipo

Cancer Res (2016) 76 (14_Supplement): LB-121.

https://doi.org/10.1158/1538-7445.AM2016-LB-121

Published: 15 July 2016

View articletitled, Abstract LB-121: DAXX is a novel Notch-1 gene target and biomarker of GSI-sensitivity in ER+ breast cancer

Journal Articles

Abstract S4-03: Identification of a notch-driven breast cancer stem cell gene signature for anti-notch therapy in an ER+ presurgical window model

Kathy S Albain, Andrei Y Zlobin, Kyle R Covington, Brian T Gallahger, Susan G Hilsenbeck, Cheryl M Czerlanis, Shelly Lo, Patricia A Robinson, Ellen R Gaynor, Constantine Godellas, Davide Bova, Kathy Czaplicki, Barbara Busby, Patrick J Stiff, Suzanne AW Fuqua, Lucio Miele, Clodia Osipo

Cancer Res (2015) 75 (9_Supplement): S4-03.

https://doi.org/10.1158/1538-7445.SABCS14-S4-03

Published: 01 May 2015

View articletitled, Abstract S4-03: Identification of a notch-driven breast cancer stem cell gene signature for anti-notch therapy in an ER+ presurgical window model

Journal Articles

Abstract 1823: Novel regulation of Jagged1 by ErbB2 in breast cancer: implications for anti-ErbB2 therapy

Clodia Osipo, Kinnari Pandya, Debra Wyatt

Cancer Res (2014) 74 (19_Supplement): 1823.

https://doi.org/10.1158/1538-7445.AM2014-1823

Published: 01 October 2014

View articletitled, Abstract 1823: Novel regulation of Jagged1 by ErbB2 in breast cancer: implications for anti-ErbB2 therapy

Journal Articles

Abstract 1829: Regulation of Mixed Lineage Kinase-3 activity by Her2 and its implication in death or survival

Subhasis Das, Gautam Sondarva, Navin Viswakarma, Rakesh Sathish Nair, Clodia Osipo, Basabi Rana, Ajay Rana

Cancer Res (2014) 74 (19_Supplement): 1829.

https://doi.org/10.1158/1538-7445.AM2014-1829

Published: 01 October 2014

View articletitled, Abstract 1829: Regulation of Mixed Lineage Kinase-3 activity by Her2 and its implication in death or survival

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Abstract 3072: Novel approach to target trastuzumab resistant, HER2+ breast cancer: Activation of PKCdelta

Abstract PO4-27-12: Increasing DAXX as a Novel Approach to Inhibit Breast Cancer Stem Cells and Estrogen Receptor-positive Tumor Recurrence

Abstract LB230: Critical role for DAXX in triple negative breast cancer

Abstract P3-11-01: Increasing DAXX Expression in ER+ Breast Cancer Cells to Overcome Endocrine Therapy Resistance

Abstract P5-12-10: A commensal’s exopolysaccharide inhibits breast cancer proliferation in vitro but promotes tumor growth in vivo

Abstract P3-05-03: KMT2D as a novel therapeutic target for HER2+ breast cancers

Abstract P1-08-22: The role of DAXX as a critical growth regulator of triple negative breast cancer

Abstract PS18-03: Differential gene expression in luminal-type invasive lobular carcinoma and invasive ductal carcinoma by MammaPrint risk stratification

Abstract 6101: Exopolysaccharide secreted by Bacillus subtilis alters breast cancer cell growth and stemness

Abstract 1859: Elucidating the role of KMT2D as a novel therapeutic target for resistant HER2+ breast cancer

DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor–Positive Breast Cancer Following Endocrine Therapy

Abstract 5845: Roles for MLL2/ KMT2D or MLL3/ KMT2C in HER+ breast cancer stem cells

Abstract 1831: PKCδ as a novel target for HER2-positive, trastuzumab resistant breast cancer

Abstract 1335: Deubiquitinase OTUD6B isoforms are important regulators of growth and proliferation

Abstract 4769: Targeting HER2 enriches Jagged1 high cancer stem cells in breast cancer

Abstract 2124: Notch-1 mediated down regulation of PTEN in trastuzumab resistant HER2+ breast cancer

Abstract LB-121: DAXX is a novel Notch-1 gene target and biomarker of GSI-sensitivity in ER+ breast cancer

Abstract S4-03: Identification of a notch-driven breast cancer stem cell gene signature for anti-notch therapy in an ER+ presurgical window model

Abstract 1823: Novel regulation of Jagged1 by ErbB2 in breast cancer: implications for anti-ErbB2 therapy

Abstract 1829: Regulation of Mixed Lineage Kinase-3 activity by Her2 and its implication in death or survival

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