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Journal Articles

Abstract 5260: Chemopreventive efficacy of everolimus and naproxen combination against carcinogen induced bladder cancer in F344 rats

Venkateshwar Madka, Gopal Pathuri, Surya P. Singh, Anil Singh, Anh Bao, Nicole Stratton, Stanley Lightfoot, Clinton J. Grubbs, Jennifer Fox, John L. Clifford, Brian Cholewa, Shizuko Sei, CV Rao

Cancer Res (2023) 83 (7_Supplement): 5260.

https://doi.org/10.1158/1538-7445.AM2023-5260

Published: 04 April 2023

View article titled, Abstract 5260: Chemopreventive efficacy of everolimus and naproxen combination against carcinogen induced bladder cancer in F344 rats

Journal Articles

Abstract 1099: Combination of bazedoxifene and lapatinib profoundly inhibits estrogen receptor positive (ER+) and Negative (ER-) mammary tumorigenesis

Altaf Mohammed, Shizuko Sei, Robert Shoemakers, Clinton J. Grubbs

Cancer Res (2020) 80 (16_Supplement): 1099.

https://doi.org/10.1158/1538-7445.AM2020-1099

Published: 15 August 2020

View article titled, Abstract 1099: Combination of bazedoxifene and lapatinib profoundly inhibits estrogen receptor positive (ER+) and Negative (ER-) mammary tumorigenesis

Journal Articles

Abstract 648: Effects of bazedoxifene and lapatinib in the prevention of estrogen receptor positive (ER⁺) and negative (ER^-) mammary cancers

Clinton J. Grubbs, Altaf Mohammed, Shizuko Sei, Robert H. Shoemaker

Cancer Res (2019) 79 (13_Supplement): 648.

https://doi.org/10.1158/1538-7445.AM2019-648

Published: 01 July 2019

View article titled, Abstract 648: Effects of bazedoxifene and lapatinib in the prevention of estrogen receptor positive (ER+) and negative (ER-) mammary cancers

Journal Articles

Abstract 4989: Efficacy of erlotinib and/or naproxen when administered by intermittent dosing schedules in the prevention of chemically induced urinary bladder cancers

Altaf Mohammed, Mark S. Miller, Ronald A. Lubet, Chen Suen, Shizuko Sei, Robert H. Shoemaker, Clinton J. Grubbs

Cancer Res (2018) 78 (13_Supplement): 4989.

https://doi.org/10.1158/1538-7445.AM2018-4989

Published: 01 July 2018

View article titled, Abstract 4989: Efficacy of erlotinib and/or naproxen when administered by intermittent dosing schedules in the prevention of chemically induced urinary bladder cancers

Journal Articles

Abstract 5246: Effects of bazedoxifene either alone or in combination with letrozole in the prevention of chemically induced mammary cancers

Barbara K. Dunn, Chen Suen, Ronald A. Lubet, Vernon E. Steele, Clinton J. Grubbs

Cancer Res (2017) 77 (13_Supplement): 5246.

https://doi.org/10.1158/1538-7445.AM2017-5246

Published: 01 July 2017

View article titled, Abstract 5246: Effects of bazedoxifene either alone or in combination with letrozole in the prevention of chemically induced mammary cancers

Journal Articles

Abstract 5255: Comparison of high-fructose and standard diets in methylnitrosourea (MNU)-induced ER⁺ mammary cancers: Altered carcinogenesis, differential effects of metformin, and metabolomic differences

Mark S. Miller, Clinton J. Grubbs, Steve Stirdivant, Ronald A. Lubet

Cancer Res (2017) 77 (13_Supplement): 5255.

https://doi.org/10.1158/1538-7445.AM2017-5255

Published: 01 July 2017

View article titled, Abstract 5255: Comparison of high-fructose and standard diets in methylnitrosourea (MNU)-induced ER+ mammary cancers: Altered carcinogenesis, differential effects of metformin, and metabolomic differences

Journal Articles

Abstract 2626: Metabolic profiles and potential pharmacodynamic biomarkers in female Sprague-Dawley rats on a standard (4% fat) or Western (20% fat) diet and treated with known active or inactive chemopreventive agents

Matthew D. Thompson, Clinton J. Grubbs, Vernon E. Steele, Mark S. Miller, Fariba Moeinpour, Edward D. Karoly, Ronald A. Lubet

Cancer Res (2016) 76 (14_Supplement): 2626.

https://doi.org/10.1158/1538-7445.AM2016-2626

Published: 15 July 2016

View article titled, Abstract 2626: Metabolic profiles and potential pharmacodynamic biomarkers in female Sprague-Dawley rats on a standard (4% fat) or Western (20% fat) diet and treated with known active or inactive chemopreventive agents

Journal Articles

Abstract 837: Reproducibility of efficacy results for chemopreventive agents in the methylnitrosourea-induced rat mammary cancer model

Vernon E. Steele, Ronald A. Lubet, Clinton J. Grubbs

Cancer Res (2016) 76 (14_Supplement): 837.

https://doi.org/10.1158/1538-7445.AM2016-837

Published: 15 July 2016

View article titled, Abstract 837: Reproducibility of efficacy results for chemopreventive agents in the methylnitrosourea-induced rat mammary cancer model

Journal Articles

Abstract 824: Effects of metfornin on mammary carcinogenesis and metabolic profiles in methylnitrosourea-treated rats on standard or Western diets

Mark S. Miller, Matthew D. Thompson, Ronald A. Lubet, Vernon E. Steele, Harold E. Seifried, Clinton J. Grubbs

Cancer Res (2016) 76 (14_Supplement): 824.

https://doi.org/10.1158/1538-7445.AM2016-824

Published: 15 July 2016

View article titled, Abstract 824: Effects of metfornin on mammary carcinogenesis and metabolic profiles in methylnitrosourea-treated rats on standard or Western diets

Journal Articles

Abstract 896: Correlation between modulation of RNA expression and the preventive and therapeutic efficacy of Tamoxifen in an ER+ model of breast cancer

Howard H. Yang, Huaitian Liu, Ronald Lubet, Clinton J. Grubbs, Holly Nicastro, Maxwell P. Lee

Cancer Res (2015) 75 (15_Supplement): 896.

https://doi.org/10.1158/1538-7445.AM2015-896

Published: 01 August 2015

View article titled, Abstract 896: Correlation between modulation of RNA expression and the preventive and therapeutic efficacy of Tamoxifen in an ER+ model of breast cancer

Journal Articles

Abstract 4657: Targeting STAT3 for mammary cancer prevention in MMTV/Neu mice employing the antagonist GLG-302

Robert H. Shoemaker, Michael W. Lovell, John J. Whalen, Fariba Moeinpour, Clinton J. Grubbs

Cancer Res (2015) 75 (15_Supplement): 4657.

https://doi.org/10.1158/1538-7445.AM2015-4657

Published: 01 August 2015

View article titled, Abstract 4657: Targeting STAT3 for mammary cancer prevention in MMTV/Neu mice employing the antagonist GLG-302

Journal Articles

Abstract 2809: Chemopreventive studies of multiple agents in the methylnitrosourea-induced ER⁺ mammary cancer model in animals on standard and Western diets

Clinton J. Grubbs, Mark S. Miller, Vernon E. Steele, Fariba Moeinpour, Harold Seifried, Brandy M. Heckman-Stoddard, Ronald A. Lubet

Cancer Res (2015) 75 (15_Supplement): 2809.

https://doi.org/10.1158/1538-7445.AM2015-2809

Published: 01 August 2015

View article titled, Abstract 2809: Chemopreventive studies of multiple agents in the methylnitrosourea-induced ER+ mammary cancer model in animals on standard and Western diets

Journal Articles

Abstract P5-11-01: Correlation of the effects of potential and known chemopreventive agents on proliferation rates in normal mammary glands and mammary cancers with their chemopreventive efficacy

Brandy M Heckman-Stoddard, Clinton J Grubbs, Fariba Moeinpour, Vernon E Steele, Ronald A Lubet

Cancer Res (2015) 75 (9_Supplement): P5-11-01.

https://doi.org/10.1158/1538-7445.SABCS14-P5-11-01

Published: 01 May 2015

View article titled, Abstract P5-11-01: Correlation of the effects of potential and known chemopreventive agents on proliferation rates in normal mammary glands and mammary cancers with their chemopreventive efficacy

Journal Articles

Abstract A20: Differential rates of proliferation and apoptosis observed in human cutaneous T-cell lymphoma cell lines, in response to treatment with 9-cis UAB30, a novel rexinoid analog

Zoe M. Verney, Venkatram R. Atigadda, Craig A. Elmets, Donald D. Muccio, Clinton J. Grubbs

Cancer Res (2011) 71 (18_Supplement): A20.

https://doi.org/10.1158/1538-7445.FBCR11-A20

Published: 28 October 2014

View article titled, Abstract A20: Differential rates of proliferation and apoptosis observed in human cutaneous T-cell lymphoma cell lines, in response to treatment with 9-cis UAB30, a novel rexinoid analog

Journal Articles

Abstract 246: Mammary cancer preventive activity of an extract of withania somnifera roots

kamel F. Khazal, Donald Hill, Clinton J. Grubbs

Cancer Res (2014) 74 (19_Supplement): 246.

https://doi.org/10.1158/1538-7445.AM2014-246

Published: 01 October 2014

View article titled, Abstract 246: Mammary cancer preventive activity of an extract of withania somnifera roots

Journal Articles

Abstract 4873: Genistein and soy isoflavone isolate decreased tumor incidence and multiplicity in a Sprague-Dawley ER-positive breast cancer model.

Holly L. Nicastro, Ronald A. Lubet, Barbara K. Dunn, Clinton J. Grubbs

Cancer Res (2013) 73 (8_Supplement): 4873.

https://doi.org/10.1158/1538-7445.AM2013-4873

Published: 15 April 2013

View article titled, Abstract 4873: Genistein and soy isoflavone isolate decreased tumor incidence and multiplicity in a Sprague-Dawley ER-positive breast cancer model.

Journal Articles

Abstract 2273: Metformin promotes tumorigenesis in animal models of cancer prevention.

Clinton J. Grubbs, Margie L. Clapper, Joel M. Reid, Vernon E. Steele, Ronald A. Lubet

Cancer Res (2013) 73 (8_Supplement): 2273.

https://doi.org/10.1158/1538-7445.AM2013-2273

Published: 15 April 2013

View article titled, Abstract 2273: Metformin promotes tumorigenesis in animal models of cancer prevention.

Journal Articles

Abstract 570: Breast cancer chemopreventive activity of a novel amide derivative of sulindac involves inhibition of PDE5, activation of PKG, and attenuation of Wnt/β-catenin signaling

Heather N. Tinsley, Bernard D. Gary, Jason Whitt, Wei Zhang, Xi Chen, Adam B. Keeton, Clinton J. Grubbs, William E. Grizzle, Gary A. Piazza

Cancer Res (2012) 72 (8_Supplement): 570.

https://doi.org/10.1158/1538-7445.AM2012-570

Published: 15 April 2012

View article titled, Abstract 570: Breast cancer chemopreventive activity of a novel amide derivative of sulindac involves inhibition of PDE5, activation of PKG, and attenuation of Wnt/β-catenin signaling

Journal Articles

Abstract 1050: Lapatinib suppresses RTK-mediated signaling through multiple signaling pathways in the chemically-induced ER+ model of mammary cancer

Jixia Li, Yeon-Yong Cho, Marna Ericson, Ronald Lubet, Clinton J. Grubbs, Ann M. Bode

Cancer Res (2011) 71 (8_Supplement): 1050.

https://doi.org/10.1158/1538-7445.AM2011-1050

Published: 15 April 2011

View article titled, Abstract 1050: Lapatinib suppresses RTK-mediated signaling through multiple signaling pathways in the chemically-induced ER+ model of mammary cancer

Journal Articles

Abstract 1039: CREB (Ser133) phosphorylation is abnormally increased in tumors showing resistance to Iressa treatment

Ann M. Bode, Jixia Li, Yong-Yeon Cho, Marna E. Ericson, Ronald A. Lubet, Clinton J. Grubbs

Cancer Res (2011) 71 (8_Supplement): 1039.

https://doi.org/10.1158/1538-7445.AM2011-1039

Published: 15 April 2011

View article titled, Abstract 1039: CREB (Ser133) phosphorylation is abnormally increased in tumors showing resistance to Iressa treatment

NARROW

Abstract 5260: Chemopreventive efficacy of everolimus and naproxen combination against carcinogen induced bladder cancer in F344 rats

Abstract 1099: Combination of bazedoxifene and lapatinib profoundly inhibits estrogen receptor positive (ER+) and Negative (ER-) mammary tumorigenesis

Abstract 648: Effects of bazedoxifene and lapatinib in the prevention of estrogen receptor positive (ER⁺) and negative (ER^-) mammary cancers

Abstract 4989: Efficacy of erlotinib and/or naproxen when administered by intermittent dosing schedules in the prevention of chemically induced urinary bladder cancers

Abstract 5246: Effects of bazedoxifene either alone or in combination with letrozole in the prevention of chemically induced mammary cancers

Abstract 5255: Comparison of high-fructose and standard diets in methylnitrosourea (MNU)-induced ER⁺ mammary cancers: Altered carcinogenesis, differential effects of metformin, and metabolomic differences

Abstract 2626: Metabolic profiles and potential pharmacodynamic biomarkers in female Sprague-Dawley rats on a standard (4% fat) or Western (20% fat) diet and treated with known active or inactive chemopreventive agents

Abstract 837: Reproducibility of efficacy results for chemopreventive agents in the methylnitrosourea-induced rat mammary cancer model

Abstract 824: Effects of metfornin on mammary carcinogenesis and metabolic profiles in methylnitrosourea-treated rats on standard or Western diets

Abstract 896: Correlation between modulation of RNA expression and the preventive and therapeutic efficacy of Tamoxifen in an ER+ model of breast cancer

Abstract 4657: Targeting STAT3 for mammary cancer prevention in MMTV/Neu mice employing the antagonist GLG-302

Abstract 2809: Chemopreventive studies of multiple agents in the methylnitrosourea-induced ER⁺ mammary cancer model in animals on standard and Western diets

Abstract P5-11-01: Correlation of the effects of potential and known chemopreventive agents on proliferation rates in normal mammary glands and mammary cancers with their chemopreventive efficacy

Abstract A20: Differential rates of proliferation and apoptosis observed in human cutaneous T-cell lymphoma cell lines, in response to treatment with 9-cis UAB30, a novel rexinoid analog

Abstract 246: Mammary cancer preventive activity of an extract of withania somnifera roots

Abstract 4873: Genistein and soy isoflavone isolate decreased tumor incidence and multiplicity in a Sprague-Dawley ER-positive breast cancer model.

Abstract 2273: Metformin promotes tumorigenesis in animal models of cancer prevention.

Abstract 570: Breast cancer chemopreventive activity of a novel amide derivative of sulindac involves inhibition of PDE5, activation of PKG, and attenuation of Wnt/β-catenin signaling

Abstract 1050: Lapatinib suppresses RTK-mediated signaling through multiple signaling pathways in the chemically-induced ER+ model of mammary cancer

Abstract 1039: CREB (Ser133) phosphorylation is abnormally increased in tumors showing resistance to Iressa treatment

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