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Clifford G. Tepper
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Journal Articles

Abstract 4206: Regional transcriptomic profiling of the head and neck squamous cell carcinoma tumor microenvironment paired with murine models identify extracellular matrix components that mediate tumor progression and immune suppression

Free
John D. Aleman, Khoa A. Nguyen, Erica Wong, Yao Ke, Hanne T. Lind, Clifford G. Tepper, Andrew C. Birkeland, Christian D. Young, Sana D. Karam, Xiao-Jing Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4206.
https://doi.org/10.1158/1538-7445.AM2024-4206
Published: 22 March 2024
View articletitled, Abstract 4206: Regional transcriptomic profiling of the head and neck squamous cell carcinoma tumor microenvironment paired with murine models identify extracellular matrix components that mediate tumor progression and immune suppression
Journal Articles

A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer

Open Access
Xing Yi Woo, Anuj Srivastava, Philip C. Mack, Joel H. Graber, Brian J. Sanderson, Michael W. Lloyd, Mandy Chen, Sergii Domanskyi, Regina Gandour-Edwards, Rebekah A. Tsai, James Keck, Mingshan Cheng, Margaret Bundy, Emily L. Jocoy, Jonathan W. Riess, William Holland, Stephen C. Grubb, James G. Peterson, Grace A. Stafford, Carolyn Paisie, Steven B. Neuhauser, R. Krishna Murthy Karuturi, Joshy George, Allen K. Simons, Margaret Chavaree, Clifford G. Tepper, Neal Goodwin, Susan D. Airhart, Primo N. Lara, Jr, Thomas H. Openshaw, Edison T. Liu, David R. Gandara, Carol J. Bult
Journal: Cancer Research
Cancer Res (2022) 82 (22): 4126–4138.
https://doi.org/10.1158/0008-5472.CAN-22-0948
Published: 15 November 2022
View articletitled, A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer
Open the PDF for A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 6314: TME subtype impacts response to combined thermal ablation and immunotherapy

Free
James Wang, Brett Z. Fite, Aris Kare, Bo Wu, Marina N. Raie, Spencer Tumbale, Ryan R. Davis, Clifford G. Tepper, Katherine Ferrara
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6314.
https://doi.org/10.1158/1538-7445.AM2022-6314
Published: 15 June 2022
View articletitled, Abstract 6314: TME subtype impacts response to combined thermal ablation and immunotherapy
Journal Articles

Abstract 334: Proteostasis by HSP70/STUB1 complex regulates androgen receptor variants expression and confers resistance to enzalutamide and abiraterone

Free
Chengfei Liu, Wei Lou, Joy C. Yang, Liangren Liu, Cameron M. Armstrong, Alan P. Lombard, Ruining Zhao, Onika DV Noel, Clifford G. Tepper, Hong-Wu Chen, Marc Dall’Era, Marc Dall’Era, Christopher P. Evans, Allen C. Gao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 334.
https://doi.org/10.1158/1538-7445.AM2019-334
Published: 01 July 2019
View articletitled, Abstract 334: Proteostasis by HSP70/STUB1 complex regulates androgen receptor variants expression and confers resistance to enzalutamide and abiraterone
Journal Articles

Abstract 4842: Overcoming EGFR and ERK-mediated resistance to enzalutamide in castration-resistant prostate cancer

Free
Thomas M. Steele, Maitreyee K. Jathal, Salma Siddiqui, Sisi Qin, Clifford G. Tepper, Ralph W. deVere White, Manish Kohli, Liewei Wang, Allen C. Gao, Paramita M. Ghosh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4842.
https://doi.org/10.1158/1538-7445.AM2019-4842
Published: 01 July 2019
View articletitled, Abstract 4842: Overcoming EGFR and ERK-mediated resistance to enzalutamide in castration-resistant prostate cancer
Journal Articles

miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src

Available to Purchase
Xu-Bao Shi, Ai-Hong Ma, Lingru Xue, Meimei Li, Hao G. Nguyen, Joy C. Yang, Clifford G. Tepper, Regina Gandour-Edwards, Christopher P. Evans, Hsing-Jien Kung, Ralph W. deVere White
Journal: Cancer Research
Cancer Res (2015) 75 (24): 5309–5317.
https://doi.org/10.1158/0008-5472.CAN-14-0795
Published: 14 December 2015
View articletitled, miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src
Open the PDF for miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src in another window
Includes: Supplementary data
Journal Articles

Abstract 5242: Utilization of next-generation sequencing to identify clinically-relevant mutations in cell-free circulating tumor DNA from patients with advanced pancreatic cancer

Free
Clifford G. Tepper, Ryan R. Davis, Stephenie Y. Liu, Rebekah A. Tsai, Irene M. Hutchins, Philip C. Mack, Thomas J. Semrad
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5242.
https://doi.org/10.1158/1538-7445.AM2015-5242
Published: 01 August 2015
View articletitled, Abstract 5242: Utilization of next-generation sequencing to identify clinically-relevant mutations in cell-free circulating tumor DNA from patients with advanced pancreatic cancer
Journal Articles

Abstract 4036: Drug repurposing to treat melanoma brain metastases

Free
Terje Sundstrøm, Jobin K. Varughese, Francisco Azuaje, Kjell Petersen, Clifford G. Tepper, Elizabeth Ingham, Lisa Even, Sarah Tam, Kai Ove Skaftnesmo, Morten Lund-Johansen, Rolf Bjerkvig, Katherine W. Ferrara, Frits A. Thorsen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4036.
https://doi.org/10.1158/1538-7445.AM2014-4036
Published: 01 October 2014
View articletitled, Abstract 4036: Drug repurposing to treat melanoma brain metastases
Journal Articles

Abstract C11: Using GCP to improve initial response to androgen deprivation in prostate cancer

Free
Benjamin A. Mooso, Maria Mudryj, Ralph W. deVere White, Paramita M. Ghosh, Rosalinda M. Savoy, Jean P. Cheung, Ruth L. Vinall, Clifford G. Tepper, Yu Wang, Salma Siddiqui, Roble G. Bedolla, Margarita Mikhailova
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): C11.
https://doi.org/10.1158/1538-7445.PRCA2012-C11
Published: 09 May 2013
View articletitled, Abstract C11: Using GCP to improve initial response to androgen deprivation in prostate cancer
Journal Articles

Abstract 2292: Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells

Free
Xu-Bao Shi, Lingru Xue, Clifford G. Tepper, Ralph W. deVere White
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2292.
https://doi.org/10.1158/1538-7445.AM2012-2292
Published: 15 April 2012
View articletitled, Abstract 2292: Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells
Journal Articles

Abstract 5040: Dysregulation of the mTOR/AKT pathway in serum tumor DNA correlates with primary and acquired resistances to erlotinib in advanced NSCLC patients

Free
Sonal J. Desai, Yi-He Ling, Ryan Davis, Clifford G. Tepper, David R. Gandara, Roman Perez-Soler, Tianhong Li
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5040.
https://doi.org/10.1158/1538-7445.AM2011-5040
Published: 15 April 2011
View articletitled, Abstract 5040: Dysregulation of the mTOR/AKT pathway in serum tumor DNA correlates with primary and acquired resistances to erlotinib in advanced NSCLC patients
Journal Articles

ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2

Available to Purchase
Ekaterina V. Kalashnikova, Alexey S. Revenko, Abigael T. Gemo, Nicolas P. Andrews, Clifford G. Tepper, June X. Zou, Robert D. Cardiff, Alexander D. Borowsky, Hong-Wu Chen
Journal: Cancer Research
Cancer Res (2010) 70 (22): 9402–9412.
https://doi.org/10.1158/0008-5472.CAN-10-1199
Published: 14 November 2010
View articletitled, ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2
Open the PDF for ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2 in another window
Includes: Supplementary data
Journal Articles

Nrdp1-Mediated Regulation of ErbB3 Expression by the Androgen Receptor in Androgen-Dependent but not Castrate-Resistant Prostate Cancer Cells

Available to Purchase
Liqun Chen, Salma Siddiqui, Swagata Bose, Benjamin Mooso, Alfredo Asuncion, Roble G. Bedolla, Ruth Vinall, Clifford G. Tepper, Regina Gandour-Edwards, XuBao Shi, Xiao-Hua Lu, Javed Siddiqui, Arul M. Chinnaiyan, Rohit Mehra, Ralph W. deVere White, Kermit L. Carraway, III, Paramita M. Ghosh
Journal: Cancer Research
Cancer Res (2010) 70 (14): 5994–6003.
https://doi.org/10.1158/0008-5472.CAN-09-4440
Published: 14 July 2010
View articletitled, Nrdp1-Mediated Regulation of ErbB3 Expression by the Androgen Receptor in Androgen-Dependent but not Castrate-Resistant Prostate Cancer Cells
Open the PDF for Nrdp1-Mediated Regulation of ErbB3 Expression by the Androgen Receptor in Androgen-Dependent but not Castrate-Resistant Prostate Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 1712: Androgen receptor splicing variants promote therapeutic resistance in prostate cancer

Free
Zhiyong Guo, Xi Yang, Feng Sun, Douglas E. Linn, Richeng Jiang, Hege Chen, Hegang Chen, Xiangtian Kong, Jonathan Melamed, Clifford G. Tepper, Hsing-Jien Kung, Angela M. H. Brodie, Joanne Edwards, Yun Qiu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1712.
https://doi.org/10.1158/1538-7445.AM10-1712
Published: 15 April 2010
View articletitled, Abstract 1712: Androgen receptor splicing variants promote therapeutic resistance in prostate cancer
Journal Articles

Abstract #2394: A novel androgen receptor splice variant promotes androgen-depletion_independent growth by regulating a unique set of target genes in human prostate cancer cells

Free
Zhiyong Guo, Xi Yang, Feng Sun, Richeng Jiang, Douglas E. Linn, Hege Chen, Hegang Chen, Xiangtian Kong, Jonathan Melamed, Clifford G. Tepper, Hsing-Jien Kung, Angela M. H. Brodie, Joanne Edwards, Yun Qiu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2394.
Published: 01 May 2009
View articletitled, Abstract #2394: A novel androgen receptor splice variant promotes androgen-depletion_independent growth by regulating a unique set of target genes in human prostate cancer cells
Journal Articles

Androgen-Induced Coactivator ANCCA Mediates Specific Androgen Receptor Signaling in Prostate Cancer

Available to Purchase
June X. Zou, Linlang Guo, Alexey S. Revenko, Clifford G. Tepper, Abigael T. Gemo, Hsing-Jien Kung, Hong-Wu Chen
Journal: Cancer Research
Cancer Res (2009) 69 (8): 3339–3346.
https://doi.org/10.1158/0008-5472.CAN-08-3440
Published: 15 April 2009
View articletitled, Androgen-Induced Coactivator ANCCA Mediates Specific Androgen Receptor Signaling in Prostate Cancer
Open the PDF for Androgen-Induced Coactivator ANCCA Mediates Specific Androgen Receptor Signaling in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion–Resistant Growth

Available to Purchase
Zhiyong Guo, Xi Yang, Feng Sun, Richeng Jiang, Douglas E. Linn, Hege Chen, Hegang Chen, Xiangtian Kong, Jonathan Melamed, Clifford G. Tepper, Hsing-Jien Kung, Angela M.H. Brodie, Joanne Edwards, Yun Qiu
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2305–2313.
https://doi.org/10.1158/0008-5472.CAN-08-3795
Published: 17 March 2009
View articletitled, A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion–Resistant Growth
Open the PDF for A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion–Resistant Growth in another window
Includes: Supplementary data
Journal Articles

Regulation of Id1 Expression by Src: Implications for Targeting of the Bone Morphogenetic Protein Pathway in Cancer

Available to Purchase
Oliver Gautschi, Clifford G. Tepper, Phillip R. Purnell, Yoshihiro Izumiya, Christopher P. Evans, Tim P. Green, Pierre Y. Desprez, Primo N. Lara, David R. Gandara, Philip C. Mack, Hsing-Jien Kung
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2250–2258.
https://doi.org/10.1158/0008-5472.CAN-07-6403
Published: 01 April 2008
View articletitled, Regulation of Id1 Expression by Src: Implications for Targeting of the Bone Morphogenetic Protein Pathway in Cancer
Open the PDF for Regulation of Id1 Expression by Src: Implications for Targeting of the Bone Morphogenetic Protein Pathway in Cancer in another window
Includes: Supplementary data
Journal Articles

Evidence for Calpain-Mediated Androgen Receptor Cleavage as a Mechanism for Androgen Independence

Available to Purchase
Stephen J. Libertini, Clifford G. Tepper, Veronica Rodriguez, David M. Asmuth, Hsing-Jien Kung, Maria Mudryj
Journal: Cancer Research
Cancer Res (2007) 67 (19): 9001–9005.
https://doi.org/10.1158/0008-5472.CAN-07-1072
Published: 01 October 2007
View articletitled, Evidence for Calpain-Mediated Androgen Receptor Cleavage as a Mechanism for Androgen Independence
Open the PDF for Evidence for Calpain-Mediated Androgen Receptor Cleavage as a Mechanism for Androgen Independence in another window
Journal Articles

Inappropriate Activation of the Androgen Receptor by Nonsteroids: Involvement of the Src Kinase Pathway and Its Therapeutic Implications

Available to Purchase
Sonal J. Desai, Ai-Hong Ma, Clifford G. Tepper, Hong-Wu Chen, Hsing-Jien Kung
Journal: Cancer Research
Cancer Res (2006) 66 (21): 10449–10459.
https://doi.org/10.1158/0008-5472.CAN-06-2582
Published: 01 November 2006
View articletitled, Inappropriate Activation of the Androgen Receptor by Nonsteroids: Involvement of the Src Kinase Pathway and Its Therapeutic Implications
Open the PDF for Inappropriate Activation of the Androgen Receptor by Nonsteroids: Involvement of the Src Kinase Pathway and Its Therapeutic Implications in another window
Includes: Supplementary data