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Claudia Chiodoni
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Journal Articles

Abstract 1712: CD36 enrichment in HER2+ mesenchymal stem cells potentiates therapy refractoriness in HER2+ breast cancer

Free
Lorenzo Castagnoli, Valeria Cancila, Martina Bigliardi, Matteo Dugo, Paola A. Corsetto, Claudia Chiodoni, Viola Regondi, Michela Francesconi, Antonino Belfiore, Andrea Vingiani, Giancarlo Pruneri, Francesca Ligorio, Elda Tagliabue, Claudio Tripodo, Claudio Vernieri, Tiziana Triulzi, Serenella M. Pupa
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1712.
https://doi.org/10.1158/1538-7445.AM2025-1712
Published: 21 April 2025
View articletitled, Abstract 1712: CD36 enrichment in HER2+ mesenchymal stem cells potentiates therapy refractoriness in HER2+ breast cancer
Journal Articles

Abstract 2159: B7-H3 as a strategic target for CAR-CIK immunotherapy to eliminate chemoresistant cancer stem cells across diverse tumor histotypes

Free
Letizia Vitali, Alessia Proment, Annamaria Massa, Chiara Donini, Alessandra Merlini, Federica Galvagno, Andrea Maria Lombardi, Elisa Vigna, Lucilla Minori, Elisa Landoni, Gianpietro Dotti, Claudia Chiodoni, Patrizia Gasparini, Silvia Novello, Valeria Leuci, Sandro Pasquali, Dario Sangiolo
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2159.
https://doi.org/10.1158/1538-7445.AM2025-2159
Published: 21 April 2025
View articletitled, Abstract 2159: B7-H3 as a strategic target for CAR-CIK immunotherapy to eliminate chemoresistant cancer stem cells across diverse tumor histotypes
Journal Articles

Abstract C014: Degradation of extracellular trap DNA sustains anti-tumor immune responses in breast cancer

Free
Sabina Sangaletti, Paola Portararo, Laura Botti, Valeria Cancila, Claudio Tripodo, Mario P. Colombo, Claudia Chiodoni
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): C014.
https://doi.org/10.1158/1538-7445.TUMBODY-C014
Published: 17 November 2024
View articletitled, Abstract C014: Degradation of extracellular trap DNA sustains anti-tumor immune responses in breast cancer
Journal Articles

Abstract B017: The double-edged sword of cystatin B in luminal-like and triple-negative breast cancers

Free
Anna Zaccaria, Chiara Ratti, Laura Botti, Sabina Sangaletti, Mario P. Colombo, Claudia Chiodoni
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): B017.
https://doi.org/10.1158/1538-7445.TUMBODY-B017
Published: 17 November 2024
View articletitled, Abstract B017: The double-edged sword of cystatin B in luminal-like and triple-negative breast cancers
Journal Articles

Abstract 3349: Identification of new potential vulnerabilities for differentiation-based therapeutic strategies against osteosarcoma

Free
Caterina Cascini, Daniele Lecis, Valeria Cancila, Katia Scotlandi, Claudio Tripodo, Mario P. Colombo, Claudia Chiodoni
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3349.
https://doi.org/10.1158/1538-7445.AM2024-3349
Published: 22 March 2024
View articletitled, Abstract 3349: Identification of new potential vulnerabilities for differentiation-based therapeutic strategies against osteosarcoma
Journal Articles

Abstract 3637: Extracellular matrix drives high-grade breast cancer immune suppression down-modulating PD-1 on Treg cells via the IL-23/SATB1 axis

Free
Giovanna Talarico, Mara Lecchi, Massimo Costanza, Claudia Chiodoni, Vera Cappelletti, Paolo Verderio, Massimo Di Nicola, Francesco Bertolini, Mario Paolo Colombo, Sabina Sangaletti
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3637.
https://doi.org/10.1158/1538-7445.AM2023-3637
Published: 04 April 2023
View articletitled, Abstract 3637: Extracellular matrix drives high-grade breast cancer immune suppression down-modulating PD-1 on Treg cells via the IL-23/SATB1 axis
Journal Articles

Abstract 3526: The transcription factor ZEB1 shapes osteosarcoma aggressiveness by affecting tumor cell differentiation and stemness features

Free
Caterina Cascini, Daniele Lecis, Laura Botti, Chiara Ratti, Valeria Cancila, Katia Scotlandi, Claudio Tripodo, Mario Paolo Colombo, Claudia Chiodoni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3526.
https://doi.org/10.1158/1538-7445.AM2023-3526
Published: 04 April 2023
View articletitled, Abstract 3526: The transcription factor ZEB1 shapes osteosarcoma aggressiveness by affecting tumor cell differentiation and stemness features
Journal Articles

ATF3 Reprograms the Bone Marrow Niche in Response to Early Breast Cancer Transformation

Open Access
Milena Perrone, Claudia Chiodoni, Mara Lecchi, Laura Botti, Barbara Bassani, Annamaria Piva, Elena Jachetti, Matteo Milani, Daniele Lecis, Elda Tagliabue, Paolo Verderio, Sabina Sangaletti, Mario P. Colombo
Journal: Cancer Research
Cancer Res (2023) 83 (1): 117–129.
https://doi.org/10.1158/0008-5472.CAN-22-0651
Published: 04 January 2023
View articletitled, ATF3 Reprograms the Bone Marrow Niche in Response to Early Breast Cancer Transformation
Open the PDF for ATF3 Reprograms the Bone Marrow Niche in Response to Early Breast Cancer Transformation in another window
Includes: Supplementary data
Journal Articles

Infiltrating Mast Cell–Mediated Stimulation of Estrogen Receptor Activity in Breast Cancer Cells Promotes the Luminal Phenotype

Available to Purchase
Maria Teresa Majorini, Valeria Cancila, Alice Rigoni, Laura Botti, Matteo Dugo, Tiziana Triulzi, Loris De Cecco, Enrico Fontanella, Elena Jachetti, Elda Tagliabue, Claudia Chiodoni, Claudio Tripodo, Mario P. Colombo, Daniele Lecis
Journal: Cancer Research
Cancer Res (2020) 80 (11): 2311–2324.
https://doi.org/10.1158/0008-5472.CAN-19-3596
Published: 02 June 2020
View articletitled, Infiltrating Mast Cell–Mediated Stimulation of Estrogen Receptor Activity in Breast Cancer Cells Promotes the Luminal Phenotype
Open the PDF for Infiltrating Mast Cell–Mediated Stimulation of Estrogen Receptor Activity in Breast Cancer Cells Promotes the Luminal Phenotype in another window
Includes: Supplementary data
Journal Articles

Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs

Free
Claudia Chiodoni, Valeria Cancila, Tiziana A. Renzi, Milena Perrone, Andrea M. Tomirotti, Sabina Sangaletti, Laura Botti, Matteo Dugo, Matteo Milani, Lucia Bongiovanni, Maurizio Marrale, Claudio Tripodo, Mario P. Colombo
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (3): 484–498.
https://doi.org/10.1158/0008-5472.CAN-19-1425
Published: 03 February 2020
View articletitled, Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs
Open the PDF for Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs in another window
Includes: Supplementary data
Journal Articles

Abstract A24: Bone marrow hematopoietic adaptation as a sensor of early, pre-invasive, epithelial malignancy

Free
Claudia Chiodoni, Andrea Massimiliano Tomirotti, Tiziana Ada Renzi, Matteo Dugo, Valeria Cancila, Claudio Tripodo, Mario Paolo Colombo
Journal: Cancer Research
Cancer Res (2018) 78 (10_Supplement): A24.
https://doi.org/10.1158/1538-7445.MOUSEMODELS17-A24
Published: 14 May 2018
View articletitled, Abstract A24: Bone marrow hematopoietic adaptation as a sensor of early, pre-invasive, epithelial malignancy
Journal Articles

Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling

Free
Claudio Tripodo, Alessia Burocchi, Pier Paolo Piccaluga, Claudia Chiodoni, Paola Portararo, Barbara Cappetti, Laura Botti, Alessandro Gulino, Alessandro Isidori, Arcangelo Liso, Giuseppe Visani, Maria Paola Martelli, Brunangelo Falini, Pier Paolo Pandolfi, Mario P. Colombo, Sabina Sangaletti
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (13): 3685–3699.
https://doi.org/10.1158/0008-5472.CAN-17-1098
Published: 02 July 2017
View articletitled, Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling
Open the PDF for Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling in another window
Includes: Supplementary data
Journal Articles

Abstract 748: Targeting the crosstalk between tumor cells and adipocytes to block breast cancer progression

Free
Tiziana Triulzi, Valentina Ciravolo, Viola Regondi, Martina Di Modica, Claudia Chiodoni, Elda Tagliabue
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 748.
https://doi.org/10.1158/1538-7445.AM2016-748
Published: 15 July 2016
View articletitled, Abstract 748: Targeting the crosstalk between tumor cells and adipocytes to block breast cancer progression
Journal Articles

Abstract 3826: Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast cancers

Free
Ada Koschorke, Lorenzo Castagnoli, Gaia C. Ghedini, Tiziana Triulzi, Claudia Chiodoni, Rossella Canese, Egidio Iorio, Manuela Iezzi, Patrizia Nanni, Elda Tagliabue, Serenella M. Pupa
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3826.
https://doi.org/10.1158/1538-7445.AM2016-3826
Published: 15 July 2016
View articletitled, Abstract 3826: Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast cancers
Journal Articles

SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias

Available to Purchase
Caterina Vitali, Claudia Bassani, Claudia Chiodoni, Elisa Fellini, Carla Guarnotta, Silvia Miotti, Sabina Sangaletti, Fabio Fuligni, Loris De Cecco, Pier P. Piccaluga, Mario P. Colombo, Claudio Tripodo
Journal: Cancer Research
Cancer Res (2015) 75 (11): 2387–2399.
https://doi.org/10.1158/0008-5472.CAN-14-3625
Published: 31 May 2015
View articletitled, SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias
Open the PDF for SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias in another window
Includes: Supplementary data
Journal Articles

Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab

Free
Lorenzo Castagnoli, Manuela Iezzi, Gaia C. Ghedini, Valentina Ciravolo, Giulia Marzano, Alessia Lamolinara, Roberta Zappasodi, Patrizia Gasparini, Manuela Campiglio, Augusto Amici, Claudia Chiodoni, Arianna Palladini, Pier Luigi Lollini, Tiziana Triulzi, Sylvie Menard, Patrizia Nanni, Elda Tagliabue, Serenella M. Pupa
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (21): 6248–6259.
https://doi.org/10.1158/0008-5472.CAN-14-0983
Published: 30 October 2014
View articletitled, Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab
Open the PDF for Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab in another window
Includes: Supplementary data
Journal Articles

Osteopontin Shapes Immunosuppression in the Metastatic Niche

Available to Purchase
Sabina Sangaletti, Claudio Tripodo, Sara Sandri, Ilaria Torselli, Caterina Vitali, Chiara Ratti, Laura Botti, Alessia Burocchi, Rossana Porcasi, Andrea Tomirotti, Mario P. Colombo, Claudia Chiodoni
Journal: Cancer Research
Cancer Res (2014) 74 (17): 4706–4719.
https://doi.org/10.1158/0008-5472.CAN-13-3334
Published: 01 September 2014
View articletitled, Osteopontin Shapes Immunosuppression in the Metastatic Niche
Open the PDF for Osteopontin Shapes Immunosuppression in the Metastatic Niche in another window
Includes: Supplementary data
Journal Articles

Inhibiting Interactions of Lysine Demethylase LSD1 with Snail/Slug Blocks Cancer Cell Invasion

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Giovanna Ferrari-Amorotti, Valentina Fragliasso, Roza Esteki, Zelia Prudente, Angela Rachele Soliera, Sara Cattelani, Gloria Manzotti, Giulia Grisendi, Massimo Dominici, Marco Pieraccioli, Giuseppe Raschellà, Claudia Chiodoni, Mario Paolo Colombo, Bruno Calabretta
Journal: Cancer Research
Cancer Res (2013) 73 (1): 235–245.
https://doi.org/10.1158/0008-5472.CAN-12-1739
Published: 02 January 2013
View articletitled, Inhibiting Interactions of Lysine Demethylase LSD1 with Snail/Slug Blocks Cancer Cell Invasion
Open the PDF for Inhibiting Interactions of Lysine Demethylase LSD1 with Snail/Slug Blocks Cancer Cell Invasion in another window
Includes: Supplementary data
Journal Articles

Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis

Available to Purchase
Sabina Sangaletti, Claudio Tripodo, Chiara Ratti, Silvia Piconese, Rossana Porcasi, Rosalba Salcedo, Giorgio Trinchieri, Mario P. Colombo, Claudia Chiodoni
Journal: Cancer Research
Cancer Res (2010) 70 (20): 7764–7775.
https://doi.org/10.1158/0008-5472.CAN-10-0471
Published: 13 October 2010
View articletitled, Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis
Open the PDF for Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis in another window
Includes: Supplementary data
Journal Articles

Macrophage-Derived SPARC Bridges Tumor Cell-Extracellular Matrix Interactions toward Metastasis

Available to Purchase
Sabina Sangaletti, Emma Di Carlo, Silvia Gariboldi, Silvia Miotti, Barbara Cappetti, Mariella Parenza, Cristiano Rumio, Rolf A. Brekken, Claudia Chiodoni, Mario P. Colombo
Journal: Cancer Research
Cancer Res (2008) 68 (21): 9050–9059.
https://doi.org/10.1158/0008-5472.CAN-08-1327
Published: 30 October 2008
View articletitled, Macrophage-Derived SPARC Bridges Tumor Cell-Extracellular Matrix Interactions toward Metastasis
Open the PDF for Macrophage-Derived SPARC Bridges Tumor Cell-Extracellular Matrix Interactions toward Metastasis in another window
Includes: Supplementary data