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Clare L. Scott
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Journal Articles

Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin

Open Access
Gwo Yaw Ho, Elizabeth L. Kyran, Justin Bedo, Matthew J. Wakefield, Darren P. Ennis, Hasan B. Mirza, Cassandra J. Vandenberg, Elizabeth Lieschke, Andrew Farrell, Anthony Hadla, Ratana Lim, Genevieve Dall, James E. Vince, Ngee Kiat Chua, Olga Kondrashova, Rosanna Upstill-Goddard, Ulla-Maja Bailey, Suzanne Dowson, Patricia Roxburgh, Rosalind M. Glasspool, Gareth Bryson, Andrew V. Biankin, for the Scottish Genomes Partnership, Susanna L. Cooke, Gayanie Ratnayake, Orla McNally, Nadia Traficante, for the Australian Ovarian Cancer Study12,13, Anna DeFazio, S. John Weroha, David D. Bowtell, Iain A. McNeish, Anthony T. Papenfuss, Clare L. Scott, Holly E. Barker
Journal: Cancer Research
Cancer Res (2022) 82 (23): 4457–4473.
https://doi.org/10.1158/0008-5472.CAN-21-4012
Published: 02 December 2022
View articletitled, Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
Open the PDF for Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin in another window
Includes: Supplementary data
Journal Articles

Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma

Free
Ksenija Nesic, Olga Kondrashova, Rachel M. Hurley, Cordelia D. McGehee, Cassandra J. Vandenberg, Gwo-Yaw Ho, Elizabeth Lieschke, Genevieve Dall, Nirashaa Bound, Kristy Shield-Artin, Marc Radke, Ashan Musafer, Zi Qing Chai, Mohammad Reza Eftekhariyan Ghamsari, Maria I. Harrell, Damien Kee, Inger Olesen, Orla McNally, Nadia Traficante, Australian Ovarian Cancer Study, Anna DeFazio, David D.L. Bowtell, Elizabeth M. Swisher, S. John Weroha, Katia Nones, Nicola Waddell, Scott H. Kaufmann, Alexander Dobrovic, Matthew J. Wakefield, Clare L. Scott
Journal: Cancer Research
Cancer Res (2021) 81 (18): 4709–4722.
https://doi.org/10.1158/0008-5472.CAN-21-0774
Published: 15 September 2021
View articletitled, Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma
Open the PDF for Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1074: Improving efficacy of microtubule inhibitors in the treatment of high-grade serous ovarian cancer and ovarian carcinosarcoma

Free
Cassandra J. Vandenberg, Gwo-Yaw Ho, Ksenija Nesic, Elizabeth M. Swisher, Sean M. Grimmond, Matthew J. Wakefield, Holly E. Barker, David D. Bowtell, Clare L. Scott
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1074.
https://doi.org/10.1158/1538-7445.AM2021-1074
Published: 01 July 2021
View articletitled, Abstract 1074: Improving efficacy of microtubule inhibitors in the treatment of high-grade serous ovarian cancer and ovarian carcinosarcoma
Journal Articles

Abstract 2057: BRCA1 D11q isoform expression impacts PARP inhibitor responses in high grade serous ovarian carcinoma patient derived xenografts

Free
Ksenija Nesic, Cassandra J. Vandenberg, Olga Kondrashova, John J. Krais, Neil Johnson, Elizabeth M. Swisher, Matthew J. Wakefield, Clare L. Scott
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2057.
https://doi.org/10.1158/1538-7445.AM2021-2057
Published: 01 July 2021
View articletitled, Abstract 2057: BRCA1 D11q isoform expression impacts PARP inhibitor responses in high grade serous ovarian carcinoma patient derived xenografts
Journal Articles

RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers

Free
John J. Krais, Yifan Wang, Andrea J. Bernhardy, Emma Clausen, Jessica A. Miller, Kathy Q. Cai, Clare L. Scott, Neil Johnson
Journal: Cancer Research
Cancer Res (2020) 80 (13): 2848–2860.
https://doi.org/10.1158/0008-5472.CAN-19-3033
Published: 02 July 2020
View articletitled, RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers
Open the PDF for RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 5885: Loss of RAD51C promoter hypermethylation confers PARP inhibitor resistance

Free
Rachel M. Hurley, Ksenija Nesic, Cordelia McGehee, Olga Kondrashova, Maria I. Harrell, Paula A. Schneider, Xiaonan Hou, Cristina Correia, Karen S. Flatten, Giada V. Zapparoli, Alexander Dobrovic, Kevin K. Lin, Thomas C. Harding, Andrea E. Wahner Hendrickson, Elizabeth M. Swisher, Matthew Wakefield, S. John Weroha, Clare L. Scott, Scott H. Kaufmann
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5885.
https://doi.org/10.1158/1538-7445.AM2018-5885
Published: 01 July 2018
View articletitled, Abstract 5885: Loss of RAD51C promoter hypermethylation confers PARP inhibitor resistance
Journal Articles

Abstract 4798: Genetically engineered mouse models of proliferative C5 high grade serous ovarian cancer

Free
Clare L. Scott, Gwo Y. Ho, Elizabeth E. Lieschke, Olga Kondrashova, Ronny Drapkin, David Bowtell, Matthew J. Wakefield
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4798.
https://doi.org/10.1158/1538-7445.AM2017-4798
Published: 01 July 2017
View articletitled, Abstract 4798: Genetically engineered mouse models of proliferative C5 high grade serous ovarian cancer
Journal Articles

Abstract 38: Using molecularly characterized patient-derived models to delineate underlying drivers and vulnerabilities of epithelial ovarian cancer

Free
Monique D. Topp, Lynne Hartley, Michele Cook, Valerie Heong, Emma Boehm, Lauren McShane, Jan Pyman, Orla McNally, Sumi Ananda, Maria I. Harell, Dariush Etemadmoghadam, Laura Galletta, Kathryn Alsop, Gillian Mitchell, Stephen B. Fox, Jeff B. Kerr, Karla J. Hutt, Scott H. Kaufmann, Australian Ovarian Cancer Study (AOCS), Elizabeth M. Swisher, David D. Bowtell, Matthew M. Wakefield, Clare L. Scott
Journal: Cancer Research
Cancer Res (2014) 74 (23_Supplement): 38.
https://doi.org/10.1158/1538-7445.CANSUSC14-38
Published: 12 December 2014
View articletitled, Abstract 38: Using molecularly characterized patient-derived models to delineate underlying drivers and vulnerabilities of epithelial ovarian cancer
Journal Articles

Abstract 3276: A novel in vivo xenograft mouse model of human high-grade serous ovarian cancer, with clinical, molecular and functional annotation relevant for pre-clinical analysis

Free
Monique Topp, Lynne Hartley, Michele Cook, Dariush Etemadmoghadam, Laura Galleta, Phillip Moss, Jan Pyman, Orla McNally, Paul Haluska, Elizabeth Swisher, Scott Kaufmann, Jeff Kerr, Matthew Wakefield, Australian Ovarian Cancer Study AOCS, David Bowtell, Clare L. Scott
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3276.
https://doi.org/10.1158/1538-7445.AM2012-3276
Published: 15 April 2012
View articletitled, Abstract 3276: A novel in vivo xenograft mouse model of human high-grade serous ovarian cancer, with clinical, molecular and functional annotation relevant for pre-clinical analysis
Journal Articles

Deciphering the Molecular Events Necessary for Synergistic Tumor Cell Apoptosis Mediated by the Histone Deacetylase Inhibitor Vorinostat and the BH3 Mimetic ABT-737

Free
Adrian P. Wiegmans, Amber E. Alsop, Michael Bots, Leonie A. Cluse, Steven P. Williams, Kellie-Marie Banks, Rachael Ralli, Clare L. Scott, Anna Frenzel, Andreas Villunger, Ricky W. Johnstone
Journal: Cancer Research
Cancer Res (2011) 71 (10): 3603–3615.
https://doi.org/10.1158/0008-5472.CAN-10-3289
Published: 15 May 2011
View articletitled, Deciphering the Molecular Events Necessary for Synergistic Tumor Cell Apoptosis Mediated by the Histone Deacetylase Inhibitor Vorinostat and the BH3 Mimetic ABT-737
Open the PDF for Deciphering the Molecular Events Necessary for Synergistic Tumor Cell Apoptosis Mediated by the Histone Deacetylase Inhibitor Vorinostat and the BH3 Mimetic ABT-737 in another window
Includes: Supplementary data
Journal Articles

Epigenetic regulation, tumorigenesis and drug-induced senescence

Free
Clare L. Scott, Hans G. Wendel, Masashi Narita, Jesus Gil, David Beach, Scott W. Lowe
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 963.
Published: 01 April 2004
View articletitled, Epigenetic regulation, tumorigenesis and drug-induced senescence