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Journal Articles

Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox

Jun Yang, Sandra Milasta, Dongli Hu, Alaa M. AlTahan, Rodrigo B. Interiano, Junfang Zhou, Jesse Davidson, Jonathan Low, Wenwei Lin, Ju Bao, Pollyanna Goh, Amit C. Nathwani, Ruoning Wang, Yingdi Wang, Su Sien Ong, Vincent A. Boyd, Brandon Young, Sourav Das, Anang Shelat, Yinan Wu, Zhenmei Li, Jie J. Zheng, Ashutosh Mishra, Yong Cheng, Chunxu Qu, Junmin Peng, Douglas R. Green, Stephen White, R. Kiplin Guy, Taosheng Chen, Andrew M. Davidoff
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4626–4638.
https://doi.org/10.1158/0008-5472.CAN-16-0826
Published: 31 August 2017
View article titled, Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox
Open the PDF for Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox in another window
Includes: Supplementary data
Journal Articles

PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation

Guo Zhu, Sherri L. Rankin, Jon D. Larson, Xiaoyan Zhu, Lionel M.L. Chow, Chunxu Qu, Jinghui Zhang, David W. Ellison, Suzanne J. Baker
Journal: Cancer Research
Cancer Res (2017) 77 (1): 123–133.
https://doi.org/10.1158/0008-5472.CAN-16-1991
Published: 02 January 2017
View article titled, PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation
Open the PDF for PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation in another window
Includes: Supplementary data
Journal Articles

Abstract B01: Biological consequences of histone mutations in the mammalian brain

Jon D. Larson, Lawryn H. Kasper, Helen R. Russell, Chunxu Qu, Xiaoyan Zhu, Peter J. McKinnon, Suzanne J. Baker
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): B01.
https://doi.org/10.1158/1538-7445.CHROMEPI15-B01
Published: 14 January 2016
View article titled, Abstract B01: Biological consequences of histone mutations in the mammalian brain
Journal Articles

Abstract IA14: The unique genomic landscape of pediatric high-grade glioma

Jon D. Larson, Andre B. Silveira, Lawryn H. Kasper, Helen R. Russell, Chunxu Qu, Peter J. McKinnon, Suzanne J. Baker
Journal: Cancer Research
Cancer Res (2015) 75 (23_Supplement): IA14.
https://doi.org/10.1158/1538-7445.BRAIN15-IA14
Published: 09 December 2015
View article titled, Abstract IA14: The unique genomic landscape of pediatric high-grade glioma
Journal Articles

Abstract B06: Knock-down of H3.3 K27M mutant protein in DIPG cells delays, but does not abrogate, tumor growth in vivo

André B. Silveira, Xiaoyan Zhu, Chunxu Qu, Suzanne Baker
Journal: Cancer Research
Cancer Res (2015) 75 (23_Supplement): B06.
https://doi.org/10.1158/1538-7445.BRAIN15-B06
Published: 09 December 2015
View article titled, Abstract B06: Knock-down of H3.3 K27M mutant protein in DIPG cells delays, but does not abrogate, tumor growth in vivo
Journal Articles

Abstract PR03: The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

Alexander K. Diaz, Gang Wu, Barbara S. Paugh, Yongjin Li, Xiaoyan Zhu, Sherri Rankin, Chunxu Qu, Xiang Chen, Junyuan Zhang, John Easton, Michael Edmonson, Charles Lu, Panduka Nagahawatte, Erin Hedlund, Michael Rusch, Stanley Pounds, Tong Lin, Arzu Onar-Thomas, Robert Huether, Richard Kriwacki, Matthew Parker, Pankaj Gupta, Jared Becksfort, Lei Wei, Heather L. Mulder, Kristy Boggs, Bhavin Vadodaria, Donald Yergeau, Kerri Ochoa, Robert S. Fulton, Lucinda S. Fulton, Chris Jones, Alberto Broniscer, Cynthia Wetmore, Amar Gajjar, Li Ding, Elaine R. Mardis, Richard K. Wilson, James R. Downing, David W. Ellison, Jinghui Zhang, Suzanne J. Baker, For the St Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project
Journal: Cancer Research
Cancer Res (2014) 74 (20_Supplement): PR03.
https://doi.org/10.1158/1538-7445.PEDCAN-PR03
Published: 09 October 2014
View article titled, Abstract PR03: The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
Journal Articles

Abstract A15: Variant histone H3 mutations associate with histone modification, DNA methylation, and gene expression changes in pediatric high-grade gliomas

Jon D. Larson, Troy A. McEachron, Chunxu Qu, Xiaoyan Zhu, Alexander K. Diaz, David W. Ellison, Brent A. Orr, Suzanne J. Baker
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): A15.
https://doi.org/10.1158/1538-7445.CEC13-A15
Published: 13 May 2014
View article titled, Abstract A15: Variant histone H3 mutations associate with histone modification, DNA methylation, and gene expression changes in pediatric high-grade gliomas
Journal Articles

Novel Oncogenic PDGFRA Mutations in Pediatric High-Grade Gliomas

Barbara S. Paugh, Xiaoyan Zhu, Chunxu Qu, Raelene Endersby, Alexander K. Diaz, Junyuan Zhang, Dorine A. Bax, Diana Carvalho, Rui M. Reis, Arzu Onar-Thomas, Alberto Broniscer, Cynthia Wetmore, Jinghui Zhang, Chris Jones, David W. Ellison, Suzanne J. Baker
Journal: Cancer Research
Cancer Res (2013) 73 (20): 6219–6229.
https://doi.org/10.1158/0008-5472.CAN-13-1491
Published: 14 October 2013
View article titled, Novel Oncogenic <em>PDGFRA</em> Mutations in Pediatric High-Grade Gliomas
Open the PDF for Novel Oncogenic <em>PDGFRA</em> Mutations in Pediatric High-Grade Gliomas in another window
Includes: Supplementary data
Journal Articles

Abstract 1434: A mouse model of the most aggressive subgroup of human medulloblastoma

Daisuke Kawauchi, Giles Robinson, Tamar Uziel, Paul Gibson, Jerold Rehg, Cuilan Gao, David Finkelstein, Chunxu Qu, Stanley Pounds, David W. Ellison, Richard J. Gilbertson, Martine F. Roussel
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1434.
https://doi.org/10.1158/1538-7445.AM2012-1434
Published: 15 April 2012
View article titled, Abstract 1434: A mouse model of the most aggressive subgroup of human medulloblastoma
Journal Articles

Abstract 3444: Enforced expression of MycN and C-Myc induces different medulloblastoma subtypes

Daisuke Kawauchi, Giles Robinson, Tamar Uziel, Jerold Rehg, Frederique Zindy, Chunxu Qu, Amar Gajjar, Richard J. Gilbertson, Martine F. Roussel
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3444.
https://doi.org/10.1158/1538-7445.AM2011-3444
Published: 15 April 2011
View article titled, Abstract 3444: Enforced expression of MycN and C-Myc induces different medulloblastoma subtypes
Journal Articles

Atoh1 Inhibits Neuronal Differentiation and Collaborates with Gli1 to Generate Medulloblastoma-Initiating Cells

Olivier Ayrault, Haotian Zhao, Frederique Zindy, Chunxu Qu, Charles J. Sherr, Martine F. Roussel
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5618–5627.
https://doi.org/10.1158/0008-5472.CAN-09-3740
Published: 30 June 2010
View article titled, Atoh1 Inhibits Neuronal Differentiation and Collaborates with Gli1 to Generate Medulloblastoma-Initiating Cells
Open the PDF for Atoh1 Inhibits Neuronal Differentiation and Collaborates with Gli1 to Generate Medulloblastoma-Initiating Cells in another window
Includes: Supplementary data