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Journal Articles

Abstract 2553: PSMA-specific, TGF-ß-insensitive CD8+ T cells derived from metastatic castration resistant prostate cancer (mCRPC) patients induce apoptosis of PSMA positive prostate cancer (PCa)

Qiang Zhang, Brian Helfand, Ximing Yang, Benedito Carneiro, Francis J. Giles, Timothy Kuzel, Chung Lee, Massimo Cristofanilli
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2553.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2553
Published: 01 July 2018
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Abstract 5585: TGF-ß insensitive PSMA-specific CD8+ T cells derived from metastatic castration resistant prostate cancer (MCRPC) patients enhance the tumor killing ability

Qiang Zhang, Timothy Kuzel, Brian Helfand, Ximing J. Yang, Weijun Qin, Chung Lee, Benedito Carneiro, Francis J. Giles
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5585.
DOI: https://doi.org/10.1158/1538-7445.AM2017-5585
Published: 01 July 2017
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Abstract 2382: Novel integration of genomic and morphological information reveals tumor tissue heterogeneity

Chen-Chung Lee, Paul Predki, Christopher Raub, Darryl Shibata, Clive Taylor, Emil Kartalov, Kenna Anderes
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2382.
DOI: https://doi.org/10.1158/1538-7445.AM2016-2382
Published: 15 July 2016
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Journal Articles

Abstract A2-66: Integrative analysis of gene expression and metabolism in isocitrate dehydrogenase 1 mutant acute myeloid leukemia and myeloid knock in mouse model

Alan Tseng, Wanda Li, Kim-Chung Lee, Karrie Yung, Ching-Wan Lam, Tak Mak
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A2-66.
DOI: https://doi.org/10.1158/1538-7445.TRANSCAGEN-A2-66
Published: 15 November 2015
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Journal Articles

Abstract B1-18: Integrative analysis of gene expression and metabolism in isocitrate dehydrogenase 1 mutant acute myeloid leukemia and myeloid knock in mouse model

Alan Tseng, Wanda Li, Kim-Chung Lee, Karrie Yung, Ching-Wan Lam, Tak Mak
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B1-18.
DOI: https://doi.org/10.1158/1538-7445.COMPSYSBIO-B1-18
Published: 15 November 2015
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Journal Articles

Abstract 4912: Screening of multiplex gene mutations using cell-free DNA in lung cancer patients

Nak-Jung Kwon, Jae Sook Sung, Ahreum Seong, Hyunmi Kim, Woo Chung Lee, Yeul Hong Kim, Kap-Seok Yang, Jeong-Sun Seo
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4912.
DOI: https://doi.org/10.1158/1538-7445.AM2015-4912
Published: 01 August 2015
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Journal Articles

Abstract 3574: Analysis of whole genome and transcriptome sequencing in single cell

Nak-Jung Kwon, Woo Chung Lee, Jiwoong Kim, Hyeri Kim, Ahreum Seong, Bong Cho Kim, Doo Hyun Park, Kap-Seok Yang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3574.
DOI: https://doi.org/10.1158/1538-7445.AM2014-3574
Published: 01 October 2014
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Journal Articles

Abstract 4038: Human prostate cancer invasion could be suppressed by 5-Aza-2′-deoxycytidine which can inhibit the TGF-β induced DNA methyltransferase (DNMT)

Qiang Zhang, Brian Helfand, Xiao Lin, Thomas Jang, Yinglu Guo, Janardan Khandekar, Timothy Michael Kuzel, Chung Lee
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4038.
DOI: https://doi.org/10.1158/1538-7445.AM2014-4038
Published: 01 October 2014
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Journal Articles

Abstract 4093: TGF-β insensitivity promotes the proliferation of human CD8+ T cells in metastatic castration resistant prostate cancer (MCRPC) patients

Qiang Zhang, Brian Helfand, Ann V. LeFever, Chung Lee, Timothy Michael Kuzel
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4093.
DOI: https://doi.org/10.1158/1538-7445.AM2014-4093
Published: 01 October 2014
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Journal Articles

Abstract LB-42: A novel method of expansion for low numbers of human CD8+ T cells in metastatic castration-resistant prostate cancer (mCRPC) patients in clinic

Qiang Zhang, Brian Helfand, Ann LeFever, Chung Lee, Timothy Michael Kuzel
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-42.
DOI: https://doi.org/10.1158/1538-7445.AM2014-LB-42
Published: 01 October 2014
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Journal Articles

Abstract IA19: Cooperation between androgen receptor and Polycomb in prostate cancer

Jonathan C. Zhao, Christine Runkle, Jianjun Yu, Longtao Wu, Hongjian Jin, Timothy Kuzel, Chung Lee, Jindan Yu
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): IA19.
DOI: https://doi.org/10.1158/1538-7445.PRCA2012-IA19
Published: 09 May 2013
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Journal Articles

Abstract LB-294: Transforming growth factor beta 3 (TGF-ß3) contributes to epithelial-mesenchymal transitions (EMT) in human prostate cancer

Qiang Zhang, Xiao Lin, Brian Helfand, Lin Chen, James Kozlowski, Ximing J Yang, Lihua J Zhu, Chung Lee
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-294.
DOI: https://doi.org/10.1158/1538-7445.AM2012-LB-294
Published: 15 April 2012
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Journal Articles

Abstract LB-3: The recruitment of PP2A by TGF-β receptors mediates the response to TGF-β-induced activation of ERK in prostate cancer

Qiang Zhang, Lin Chen, Brian Helfand, James Kozlowski, Charles B Brendler, Timothy M. Kuzel, Chung Lee
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-3.
DOI: https://doi.org/10.1158/1538-7445.AM2011-LB-3
Published: 15 April 2011
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Journal Articles

Abstract LB-85: TGF-ß regulates its own expression and down-regulates its own receptors in prostate cancer (CaP) cells through a positive feedback pathway mediated by DNA methyltransferase

Qiang Zhang, Lin Chen, Brian Helfand, Lihua J Zhu, Norm Smith, Yinglu Guo, Borko Javonovic, Chung Lee
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-85.
DOI: https://doi.org/10.1158/1538-7445.AM10-LB-85
Published: 15 April 2010
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Journal Articles

Abstract 3185: Expression of DNA methyltransferase (DNMT) induced by transforming growth factor-ß (TGF-ß) promotes progress of prostate cancer

Qiang Zhang, Lin Chen, Brian Helfand, Thomas Jang, Yinglu Guo, Chung Lee
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3185.
DOI: https://doi.org/10.1158/1538-7445.AM10-3185
Published: 15 April 2010
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Journal Articles

Abstract #LB-118:   Transforming Growth Factor Beta (TGF-\#946;) dependent phosphorylation of ERK may relate to the loss of TGF-\#946; receptor expression in prostate cancer cells.

Qiang Zhang, Brian Helfand, Thomas Jang, Borko Javonovic, Julie Zhu, Norm Smith, Lin Chen, Ximing J Yang, Chung Lee
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-118.
Published: 01 May 2009
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Journal Articles

OSU-03012, a Novel Celecoxib Derivative, Induces Reactive Oxygen Species–Related Autophagy in Hepatocellular Carcinoma

Ming Gao, Pei Yen Yeh, Yen-Shen Lu, Chih-Hung Hsu, Kuen-Feng Chen, Wei-Chung Lee, Wen-Chi Feng, Ching-Shih Chen, Min-Liang Kuo, Ann-Lii Cheng
Journal: Cancer Research
Cancer Res (2008) 68 (22): 9348–9357.
DOI: https://doi.org/10.1158/0008-5472.CAN-08-1642
Published: 14 November 2008
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Journal Articles

Potential synergistic anti-tumor effects between sorafenib and the MEK inhibitor CI1040 in hepatocellular carcinoma (HCC)

Da-Liang Ou, Ying-Chun Shen, Sung-Liang Yu, Wei-Chung Lee, Ling-Chun Yeh, Chiun Hsu, Ann-Lii Cheng
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1435.
Published: 01 May 2008
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Journal Articles

Tgf-β Mediated inhibition of infiltration of cd8+ t cells promotes the progress human prostate cancer in clinic

Qiang Zhang, Shilajit Kundu, Lin Chen, Norm Smith, Ximing J Yang, Thomas Jang, Borko Javonovic, Julie Zhu, Chung Lee
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-225.
Published: 01 May 2008
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Journal Articles

Effect of Dominant Negative Transforming Growth Factor-β Receptor Type II on Cytotoxic Activity of RAW 264.7, a Murine Macrophage Cell Line

Geun Taek Lee, Jun Hyuk Hong, Cheol Kwak, Jaesung Woo, Victoria Liu, Chung Lee, Isaac Yi Kim
Journal: Cancer Research
Cancer Res (2007) 67 (14): 6717–6724.
DOI: https://doi.org/10.1158/0008-5472.CAN-06-4263
Published: 17 July 2007
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