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Chuanshu Huang
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Journal Articles

Abstract 5123: Up-regulation of KRT14 promotes EMT in basal muscle-invasive bladder cancer through IGF2BP1/FTO dependence on methyladenosine-modified SNAI1

Chuanshu Huang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5123.
https://doi.org/10.1158/1538-7445.AM2025-5123
Published: 21 April 2025
View articletitled, Abstract 5123: Up-regulation of KRT14 promotes EMT in basal muscle-invasive bladder cancer through IGF2BP1/FTO dependence on methyladenosine-modified SNAI1
Journal Articles

Abstract 1552: Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation

Chuanshu Huang, Tengda Li, Honglei Jin
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1552.
https://doi.org/10.1158/1538-7445.AM2024-1552
Published: 22 March 2024
View articletitled, Abstract 1552: Tumorigenesis of basal muscle invasive bladder cancer was mediated by PTEN protein degradation resulting from SNHG1 upregulation
Journal Articles

Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization

Jae Young So, Nicolas Skrypek, Howard H. Yang, Anand S. Merchant, George W. Nelson, Wei-Dong Chen, Hiroki Ishii, Jennifer M. Chen, Gangqing Hu, Bhagelu R. Achyut, Esther C. Yoon, Liying Han, Chuanshu Huang, Margaret C. Cam, Keji Zhao, Maxwell P. Lee, Li Yang
Journal: Cancer Research
Cancer Res (2020) 80 (12): 2612–2627.
https://doi.org/10.1158/0008-5472.CAN-19-3339
Published: 15 June 2020
View articletitled, Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
Open the PDF for Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization in another window
Includes: Supplementary data
Journal Articles

Abstract 4340: A novel fluoride (ChlA-F) transcriptionally upregulates miR494 via a HuR/JunB axis to inhibit cell invasion in human bladder cancers

Zhongxian Tian, Xiaohui Hua, Jiheng Xu, Junlan Zhu, Jingxia li, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4340.
https://doi.org/10.1158/1538-7445.AM2019-4340
Published: 01 July 2019
View articletitled, Abstract 4340: A novel fluoride (ChlA-F) transcriptionally upregulates miR494 via a HuR/JunB axis to inhibit cell invasion in human bladder cancers
Journal Articles

Abstract 785: The inhibitory effect of compound ChlA-F onhuman bladder cancer cell invasion can be attributed to its blockage of SOX2 protein

Xiaohui Hua, Jiheng Xu, Chuanshu Huang, Jingxia Li, Zhongxian Tian, Haishan Huang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 785.
https://doi.org/10.1158/1538-7445.AM2019-785
Published: 01 July 2019
View articletitled, Abstract 785: The inhibitory effect of compound ChlA-F onhuman bladder cancer cell invasion can be attributed to its blockage of SOX2 protein
Journal Articles

Abstract 1062: Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer

Zhongxian Tian, Honglei Jin, Jingxia Li, Chao Huang, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1062.
https://doi.org/10.1158/1538-7445.AM2018-1062
Published: 01 July 2018
View articletitled, Abstract 1062: Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer
Journal Articles

Abstract 107: Interaction of BIR domain of XIAP with Sp1/E2F1 activates MMP2 and bladder cancer cell invasion by inhibiting src protein translation

Xiaohui Hua, Jiheng Xu, Honglei Jin, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 107.
https://doi.org/10.1158/1538-7445.AM2018-107
Published: 01 July 2018
View articletitled, Abstract 107: Interaction of BIR domain of XIAP with Sp1/E2F1 activates MMP2 and bladder cancer cell invasion by inhibiting src protein translation
Journal Articles

Abstract 2306: Transcriptional and post-transcriptional upregulation of p27 mediates growth inhibition of isorhapontigenin/ISO on human bladder cancer cells

Jiheng Xu, Jingxia Li, Chuanshu Huang, Haishan Huang, Guosong Jiang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2306.
https://doi.org/10.1158/1538-7445.AM2018-2306
Published: 01 July 2018
View articletitled, Abstract 2306: Transcriptional and post-transcriptional upregulation of p27 mediates growth inhibition of isorhapontigenin/ISO on human bladder cancer cells
Journal Articles

Abstract 5857: Isorhapontigenin inhibits triple-negative breast cancer via activating NRF2-mediated pathway

Yusha Zhu, Anthony Murphy, Thomas Kluz, Bo Li, Max Costa, Chuanshu Huang, Hong Sun
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5857.
https://doi.org/10.1158/1538-7445.AM2018-5857
Published: 01 July 2018
View articletitled, Abstract 5857: Isorhapontigenin inhibits triple-negative breast cancer via activating NRF2-mediated pathway
Journal Articles

Abstract 499: MicroRNA-411 downregulation promotes tumorigenesis and inhibits chemotherapy sensitivity by upregulating MLLT11 expression in human bladder cancer

Honglei Jin, Haishan Huang, Chuanshu Huang, Xiaohui Hua, Junlan Zhu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 499.
https://doi.org/10.1158/1538-7445.AM2018-499
Published: 01 July 2018
View articletitled, Abstract 499: MicroRNA-411 downregulation promotes tumorigenesis and inhibits chemotherapy sensitivity by upregulating MLLT11 expression in human bladder cancer
Journal Articles

Abstract 4383: CD44s is a crucial ATG7 downstream regulator for formation of sphere, a key stem-like property, invasion and lung metastasis of human bladder cancer/BC cells

Xiaohui Hua, Xun Che, Jiheng Xu, Chuanshu Huang, Grace Huang, Wei Dai
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4383.
https://doi.org/10.1158/1538-7445.AM2018-4383
Published: 01 July 2018
View articletitled, Abstract 4383: CD44s is a crucial ATG7 downstream regulator for formation of sphere, a key stem-like property, invasion and lung metastasis of human bladder cancer/BC cells
Journal Articles

Abstract 3305: Autophagic induction through upregulation of sestrin-2 transcription and mRNA stability mediates the anticancer effect of new compound ChlA-F

Xiaohui Hua, Chuanshu Huang, Xueru Wu, Jingxia Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3305.
https://doi.org/10.1158/1538-7445.AM2017-3305
Published: 01 July 2017
View articletitled, Abstract 3305: Autophagic induction through upregulation of sestrin-2 transcription and mRNA stability mediates the anticancer effect of new compound ChlA-F
Journal Articles

Abstract 1898: MEG3 as a competing endogenous RNA binds with miR-27a to promote PHLPP2 protein translation, and consequently impairs bladder cancer invasion

Chao Huang, Xin Liao, Jingxia Li, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1898.
https://doi.org/10.1158/1538-7445.AM2017-1898
Published: 01 July 2017
View articletitled, Abstract 1898: MEG3 as a competing endogenous RNA binds with miR-27a to promote PHLPP2 protein translation, and consequently impairs bladder cancer invasion
Journal Articles

Abstract 526: NFκB p65 overexpression promotes bladder cancer migration via FBW7-mediated degradation of RhoGDIα protein

Yang Li, Junlan Zhu, Jingxia Li, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 526.
https://doi.org/10.1158/1538-7445.AM2017-526
Published: 01 July 2017
View articletitled, Abstract 526: NFκB p65 overexpression promotes bladder cancer migration via FBW7-mediated degradation of RhoGDIα protein
Journal Articles

Abstract 3310: Atg7 overexpression promotes bladder cancer invasion via autophagic removal of AUF1 protein and subsequently increased RhoGDI2 mRNA stability in vitro and in vivo

Junlan Zhu, Yang Li, Chuanshu Huang, Haishan Huang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3310.
https://doi.org/10.1158/1538-7445.AM2017-3310
Published: 01 July 2017
View articletitled, Abstract 3310: Atg7 overexpression promotes bladder cancer invasion via autophagic removal of AUF1 protein and subsequently increased RhoGDI2 mRNA stability in vitro and in vivo
Journal Articles

Abstract 533: XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell

Xin Liao, Chao Huang, Jingxia Li, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 533.
https://doi.org/10.1158/1538-7445.AM2017-533
Published: 01 July 2017
View articletitled, Abstract 533: XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell
Journal Articles

Abstract 4641: Crucial role of c-Jun phosphorylation at Ser63/73 mediated by PHLPP protein degradation in the Cheliensisin A (Chel A) inhibition of cell transformation

Chuanshu Huang, Junlan Zhu, Jingxia Li
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4641.
https://doi.org/10.1158/1538-7445.AM2015-4641
Published: 01 August 2015
View articletitled, Abstract 4641: Crucial role of c-Jun phosphorylation at Ser63/73 mediated by PHLPP protein degradation in the Cheliensisin A (Chel A) inhibition of cell transformation
Journal Articles

Abstract 5107: Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines

Honglei Jin, Jingxia Li, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5107.
https://doi.org/10.1158/1538-7445.AM2015-5107
Published: 01 August 2015
View articletitled, Abstract 5107: Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines
Journal Articles

Abstract 5104: Isorhapontigenin (ISO) inhibits cancer invasion by enhancing FOXO1 transcription through targeting STAT1 phosphorylation at Tyr701

Lei Xue, Guosong Jiang, Jingxia Li, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5104.
https://doi.org/10.1158/1538-7445.AM2015-5104
Published: 01 August 2015
View articletitled, Abstract 5104: Isorhapontigenin (ISO) inhibits cancer invasion by enhancing FOXO1 transcription through targeting STAT1 phosphorylation at Tyr701
Journal Articles

Abstract 5103: Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration

Jing An, Dongyun Zhang, Chuanshu Huang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5103.
https://doi.org/10.1158/1538-7445.AM2015-5103
Published: 01 August 2015
View articletitled, Abstract 5103: Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration