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Journal Articles

Abstract 6051: Opposing function of USP5 in MRE11 endonuclease activity to evade anti-tumor immunity

Chuan-Chun Lee, Wan-Rong Wu, Liang-Chih Liu, Ting-Yi Liao, You-Zhe Lin, Fang-Ying Lin, Yi-Chun Shen, Feng-Chi Chung, Yuan-Liang Wang, Chih-Hao Lu, Wei-Chung Cheng, Wei-Chao Chang, Yi-Chuan Li, Chih-Tung Lin, Chung-Yu Chen, Sheng-Wen Chen, Hsin-An Shih, Steven Lin, I-Wen Chou, Chen-Yuan Lin, Chang-Feng Chiu, Shao-Chun Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6051.
https://doi.org/10.1158/1538-7445.AM2025-6051
Published: 21 April 2025
View articletitled, Abstract 6051: Opposing function of USP5 in MRE11 endonuclease activity to evade anti-tumor immunity
Journal Articles

Abstract CT119: Safety and efficacy of HS-10370 in KRAS G12C-mutated solid tumors including non-small cell lung cancer (NSCLC)

Xiaorong Dong, Xiangjiao Meng, Yan Zhang, Yan Wang, Jianhua Chen, Liang Han, Qiming Wang, Zhong Lin, Hongying Wei, Siheng Lin, Chuan Li, Qiong Wu
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT119.
https://doi.org/10.1158/1538-7445.AM2024-CT119
Published: 05 April 2024
View articletitled, Abstract CT119: Safety and efficacy of HS-10370 in KRAS G12C-mutated solid tumors including non-small cell lung cancer (NSCLC)
Journal Articles

Abstract CT201: HS-10365, a highly potent and selective RET tyrosine kinase inhibitor, demonstrates robust activity in RET fusion positive NSCLC patients

Shun Lu, Qiming Wang, Lin Wu, Ligang Xing, Yintao Li, Liang Han, Xiaorong Dong, Hongying Wei, Wen Xu, Chuan Li, Liuqing Yang, Qiong Wu
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT201.
https://doi.org/10.1158/1538-7445.AM2023-CT201
Published: 14 April 2023
View articletitled, Abstract CT201: HS-10365, a highly potent and selective RET tyrosine kinase inhibitor, demonstrates robust activity in RET fusion positive NSCLC patients
Journal Articles

Abstract 5462: Elevated creatine phosphokinase (CPK) as a strong predictor of aumolertinib (Au) treatment response in patients (pts) with advanced non-small cell lung cancer (NSCLC): post-hoc analysis of AENEAS

Shun Lu, Chuan Li, Hong Jian, Xiaorong Dong, Jianhua Chen, Gongyan Chen, Yuping Sun, Yinghua Ji, Jiawei Wei, Si Sun, Zhenzhong Su, Qiu Sun, Hongying Wei, Qiong Wu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5462.
https://doi.org/10.1158/1538-7445.AM2023-5462
Published: 04 April 2023
View articletitled, Abstract 5462: Elevated creatine phosphokinase (CPK) as a strong predictor of aumolertinib (Au) treatment response in patients (pts) with advanced non-small cell lung cancer (NSCLC): post-hoc analysis of AENEAS
Journal Articles

Abstract 827: A journey to deconvolute the multifaceted functions and context-dependency of cancer driver genes

Hongchen Cai, Su Kit Chew, Chuan Li, Christopher W. Murray, Laura Andrejka, Jess D. Hebert, Min K. Tsai, Rui Tang, Nicholas W. Hughes, Emily G. Shuldiner, Emily L. Ashkin, Shi Ya C. Lee, Maryam Yousefi, Dmitri A. Petrov, Charles Swanton, Monte W. Winslow
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 827.
https://doi.org/10.1158/1538-7445.AM2022-827
Published: 15 June 2022
View articletitled, Abstract 827: A journey to deconvolute the multifaceted functions and context-dependency of cancer driver genes
Journal Articles

Abstract 821: Dissecting the role of Stag2 in lung adenocarcinoma

Emily L. Ashkin, Hongchen Cai, Yuning J. Tang, Chuan Li, Su Kit Chew, King Hung, Julia Belk, Saswati Karmakar, Jess Hebert, Maryam Yousefi, Charles Swanton, Dmitri A. Petrov, Monte Winslow
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 821.
https://doi.org/10.1158/1538-7445.AM2022-821
Published: 15 June 2022
View articletitled, Abstract 821: Dissecting the role of Stag2 in lung adenocarcinoma
Journal Articles

Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities

Maryam Yousefi, Gábor Boross, Carly Weiss, Christopher W. Murray, Jess D. Hebert, Hongchen Cai, Emily L. Ashkin, Saswati Karmakar, Laura Andrejka, Leo Chen, Minwei Wang, Min K. Tsai, Wen-Yang Lin, Chuan Li, Pegah Yakhchalian, Caterina I. Colón, Su-Kit Chew, Pauline Chu, Charles Swanton, Christian A. Kunder, Dmitri A. Petrov, Monte M. Winslow
Journal: Cancer Research
Cancer Res (2022) 82 (8): 1589–1602.
https://doi.org/10.1158/0008-5472.CAN-22-0059
Published: 15 April 2022
View articletitled, Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities
Open the PDF for Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities in another window
Includes: Supplementary data
Journal Articles

Quantitative In Vivo Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma

Chuan Li, Wen-Yang Lin, Hira Rizvi, Hongchen Cai, Christopher D. McFarland, Zoe N. Rogers, Maryam Yousefi, Ian P. Winters, Charles M. Rudin, Dmitri A. Petrov, Monte M. Winslow
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4570–4580.
https://doi.org/10.1158/0008-5472.CAN-21-0716
Published: 01 September 2021
View articletitled, Quantitative In Vivo Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Abstract 1094: Genetic determinants of EGFR-driven lung cancer growth and therapeutic response in vivo

Giorgia Foggetti, Chuan Li, Hongchen Cai, Wen-Yang Lin, Deborah Ayeni, Katherine Hastings, Laura Andrejka, Dylan Maghini, Robert Homer, Dmitri A. Petrov, Monte M. Winslow, Katerina Politi
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1094.
https://doi.org/10.1158/1538-7445.AM2020-1094
Published: 15 August 2020
View articletitled, Abstract 1094: Genetic determinants of EGFR-driven lung cancer growth and therapeutic response in vivo
Journal Articles

Abstract CT190: A multicenter, open-label, single-arm, phase II study: The third generation EGFR tyrosine kinase inhibitor almonertinib for pretreated EGFR T790M-positive locally advanced or metastatic non-small cell lung cancer (APOLLO)

Shun Lu, Qiming Wang, Guojun Zhang, Xiaorong Dong, Cheng-Ta Yang, Yong Song, Gee-Chen Chang, You Lu, Hongming Pan, Chao-Hua Chiu, Zhehai Wang, Jifeng Feng, Jianying Zhou, Xingxiang Xu, Renhua Guo, Jianhua Chen, Haihua Yang, Yuan Chen, Zhuang Yu, Her-Shyong Shiah, Chin-Chou Wang, Nong Yang, Jian Fang, Ping Wang, Kai Wang, Yanping Hu, Jianxing He, Ziping Wang, Jianhua Shi, Shaoshui Chen, Qiong Wu, Changan Sun, Chuan Li, Hongying Wei, Ying Cheng, Wu-Chou Su, Te-Chun Hsia, Jiuwei Cui, Yuping Sun, James Chih-Hsin Yang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT190.
https://doi.org/10.1158/1538-7445.AM2020-CT190
Published: 15 August 2020
View articletitled, Abstract CT190: A multicenter, open-label, single-arm, phase II study: The third generation EGFR tyrosine kinase inhibitor almonertinib for pretreated EGFR T790M-positive locally advanced or metastatic non-small cell lung cancer (APOLLO)
Journal Articles

Abstract IA26: Multiplexed functional cancer genomics

Hongchen Cai, Chuan Li, Su Kit Chew, Maryam Yousefi, Giorgia Foggetti, Wen-Yang Lin, Zoë N. Rogers, Ian P. Winters, Christopher D. McFarland, Katherina Politi, Charlie Swanton, Dmitri A. Petrov, Monte M. Winslow
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): IA26.
https://doi.org/10.1158/1538-7445.CAMODELS2020-IA26
Published: 02 June 2020
View articletitled, Abstract IA26: Multiplexed functional cancer genomics
Journal Articles

Macrophage ABHD5 Suppresses NFκB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis

Shenglan Shang, Xinran Ji, Lili Zhang, Jun Chen, Chuan Li, Rongchen Shi, Wei Xiang, Xia Kang, Dapeng Zhang, Fan Yang, Rongyang Dai, Peng Chen, Shan Chen, Yongchuan Chen, Yongsheng Li, Hongming Miao
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5513–5526.
https://doi.org/10.1158/0008-5472.CAN-19-1059
Published: 01 November 2019
View articletitled, Macrophage ABHD5 Suppresses NFκB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis
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Includes: Supplementary data
Journal Articles

An Optimized Telomerase-Specific Lentivirus for Optical Imaging of Tumors

Song-Tao Yu, Yin-Bing Yang, Guang-Ping Liang, Chuan Li, Ling Chen, Chun-Meng Shi, Xu-Dong Tang, Chang-Zhu Li, Ling Li, Guo-Zheng Wang, Yu-Yun Wu, Shi-Ming Yang, Dian-Chun Fang
Journal: Cancer Research
Cancer Res (2010) 70 (7): 2585–2594.
https://doi.org/10.1158/0008-5472.CAN-09-3841
Published: 31 March 2010
View articletitled, An Optimized Telomerase-Specific Lentivirus for Optical Imaging of Tumors
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Journal Articles

Abstract #976: Gastric cardia adenocarcinoma in Chinese: Histopathological analysis on 7301 patients from Linxian and nearby counties, the high risk area in Henan, Northern China.

Li Dong Wang, Yan Wang, Ji Lin Li, Xue Ke Zhao, Sheng Li Zhou, Guo Qiang Kong, Hai Yan Wang, Zhi Min Zhao, Dong Mei Fan, Yi Yuan, Yong Hong Ai, Jie Zhi Yang, Zhi Qiang Sun, Xing Chuan Li, Jin Ya Tian, Yan Jin, Qin Lu, Xue Min Li, Song Liang Qiu, Jing Li Ren
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 976.
Published: 01 May 2009
View articletitled, Abstract #976: Gastric cardia adenocarcinoma in Chinese: Histopathological analysis on 7301 patients from Linxian and nearby counties, the high risk area in Henan, Northern China.
Journal Articles

Stimulation of Tumor Growth by Human Soluble Intercellular Adhesion Molecule-1

Yong Song Gho, Phillia N. Kim, Hao-Chuan Li, Michael Elkin, Hynda K. Kleinman
Journal: Cancer Research
Cancer Res (2001) 61 (10): 4253–4257.
Published: 01 May 2001
View articletitled, Stimulation of Tumor Growth by Human Soluble Intercellular Adhesion Molecule-1
Open the PDF for Stimulation of Tumor Growth by Human Soluble Intercellular Adhesion Molecule-1 in another window
Journal Articles

Microvascular Mechanisms of Change in Tumor Blood Flow Due to Angiotensin II, Epinephrine, and Methoxamine: A Functional Morphometric Study

Katsuyoshi Hori, Qiu-Hang Zhang, Sachiko Saito, Shigeru Tanda, Hao-Chuan Li, Maroh Suzuki
Journal: Cancer Research
Cancer Res (1993) 53 (22): 5528–5534.
Published: 01 November 1993
View articletitled, Microvascular Mechanisms of Change in Tumor Blood Flow Due to Angiotensin II, Epinephrine, and Methoxamine: A Functional Morphometric Study
Open the PDF for Microvascular Mechanisms of Change in Tumor Blood Flow Due to Angiotensin II, Epinephrine, and Methoxamine: A Functional Morphometric Study in another window