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Christopher Straub
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Journal Articles

Abstract LB-139: IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism

Alexandra R. Grassian, Seth Parker, Shawn Davidson, Ajit Divakaruni, Courtney Green, Xiamei Zhang, Kelly Slocum, Minying Pu, Fallon Lin, Chad Vickers, Carol Joud-Caldwell, Franklin Chung, Hong Yin, Erika Handly, Christopher Straub, Joseph D. Growney, Matt Vander Heiden, Anne Murphy, Raymond Pagliarini, Christian Metallo
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-139.
https://doi.org/10.1158/1538-7445.AM2014-LB-139
Published: 01 October 2014
View article titled, Abstract LB-139: IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism
Journal Articles

IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism

Alexandra R. Grassian, Seth J. Parker, Shawn M. Davidson, Ajit S. Divakaruni, Courtney R. Green, Xiamei Zhang, Kelly L. Slocum, Minying Pu, Fallon Lin, Chad Vickers, Carol Joud-Caldwell, Franklin Chung, Hong Yin, Erika D. Handly, Christopher Straub, Joseph D. Growney, Matthew G. Vander Heiden, Anne N. Murphy, Raymond Pagliarini, Christian M. Metallo
Journal: Cancer Research
Cancer Res (2014) 74 (12): 3317–3331.
https://doi.org/10.1158/0008-5472.CAN-14-0772-T
Published: 12 June 2014
View article titled, IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism
Open the PDF for IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism in another window
Includes: Supplementary data
Journal Articles

Abstract 138: Therapeutic targeting of inhibitor of apoptosis proteins

Leigh S. Zawel, Christopher Straub, Brant Firestone, John Sullivan, Kymberly Levine, Dale Porter, Colleen Conway, Guizhi Yang, Hui Gao, Dan He, Joanna Slisz, Michael Morrissey, John Monahan, Rebecca Mosher, Frank Stegmeier, Feng He, Ly Pham, Fan Yang, Julian Chen, Tim Ramsey, Megan Yao, Stephen Fawell
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 138.
https://doi.org/10.1158/1538-7445.AM10-138
Published: 15 April 2010
View article titled, Abstract 138: Therapeutic targeting of inhibitor of apoptosis proteins
Journal Articles

Mechanism of action studies using a Smac mimetic reveal positive and negative roles of inhibitor of apoptosis proteins (IAPs) in TNFα signaling

Leigh Zawel, Alex Gaither, Dale Porter, Yao Yao, Christopher Straub, Tim Ramsey, Vadim Iourgenko, Huang Alan, Robert Schlegel, Mark Labow, Stephen Fawell, William Sellers
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): SY26-04.
Published: 01 May 2008
View article titled, Mechanism of action studies using a Smac mimetic reveal positive and negative roles of inhibitor of apoptosis proteins (IAPs) in TNFα signaling
Journal Articles

A Smac Mimetic Rescue Screen Reveals Roles for Inhibitor of Apoptosis Proteins in Tumor Necrosis Factor-α Signaling

Alex Gaither, Dale Porter, Yao Yao, Jason Borawski, Guang Yang, Jerry Donovan, David Sage, Joanna Slisz, Mary Tran, Christopher Straub, Tim Ramsey, Vadim Iourgenko, Alan Huang, Yan Chen, Robert Schlegel, Mark Labow, Stephen Fawell, William R. Sellers, Leigh Zawel
Journal: Cancer Research
Cancer Res (2007) 67 (24): 11493–11498.
https://doi.org/10.1158/0008-5472.CAN-07-5173
Published: 18 December 2007
View article titled, A Smac Mimetic Rescue Screen Reveals Roles for Inhibitor of Apoptosis Proteins in Tumor Necrosis Factor-α Signaling
Open the PDF for A Smac Mimetic Rescue Screen Reveals Roles for Inhibitor of Apoptosis Proteins in Tumor Necrosis Factor-α Signaling in another window
Includes: Supplementary data