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Christopher S. Hackett
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Journal Articles

Abstract 40: Persistence but not antitumor efficacy of CAR-engineered lymphocytes is governed by a FAS/FAS ligand auto-regulatory circuit

Fei Yi, Tal Cohen, Paul Zumbo, Razan Eltilib, Hannah Arkin, Michael Gormally, Christopher S. Hackett, Korbinian Kropp, Smita Chandran, Jae H. Park, Doron Betel, Christopher A. Klebanoff
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 40.
https://doi.org/10.1158/1538-7445.AM2024-40
Published: 22 March 2024
View article titled, Abstract 40: Persistence but not antitumor efficacy of CAR-engineered lymphocytes is governed by a FAS/FAS ligand auto-regulatory circuit
Journal Articles

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

Aria Vaishnavi, Joseph Juan, Maebh Jacob, Christopher Stehn, Eric E. Gardner, Michael T. Scherzer, Sophia Schuman, J. Edward Van Veen, Brandon Murphy, Christopher S. Hackett, Adam J. Dupuy, Steven A. Chmura, Louise van der Weyden, Justin Y. Newberg, Annie Liu, Karen Mann, Alistair G. Rust, William A. Weiss, Conan G. Kinsey, David J. Adams, Allie Grossmann, Michael B. Mann, Martin McMahon
Journal: Cancer Research
Cancer Res (2022) 82 (22): 4261–4273.
https://doi.org/10.1158/0008-5472.CAN-21-3214
Published: 15 November 2022
View article titled, Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAF<sup>V600E</sup>-Driven Lung Tumorigenesis
Open the PDF for Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAF<sup>V600E</sup>-Driven Lung Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 3413: A genetic analysis of splicing in neuroblastoma identifies opposing functions for FUBP1 splice variants in MYC regulation

Justin Chen, Christopher S. Hackett, Shile Zhang, Young K. Song, Annette Molinaro, David A. Quigley, Allan Balmain, William C. Gustafson, Terry A. Van Dyke, Pui-Yan Kwok, Javed Khan, William A. Weiss
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3413.
https://doi.org/10.1158/1538-7445.AM2014-3413
Published: 01 October 2014
View article titled, Abstract 3413: A genetic analysis of splicing in neuroblastoma identifies opposing functions for FUBP1 splice variants in MYC regulation
Journal Articles

Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality

Lara S. Collier, David J. Adams, Christopher S. Hackett, Laura E. Bendzick, Keiko Akagi, Michael N. Davies, Miechaleen D. Diers, Fausto J. Rodriguez, Aaron M. Bender, Christina Tieu, Ilze Matise, Adam J. Dupuy, Neal G. Copeland, Nancy A. Jenkins, J. Graeme Hodgson, William A. Weiss, Robert B. Jenkins, David A. Largaespada
Journal: Cancer Research
Cancer Res (2009) 69 (21): 8429–8437.
https://doi.org/10.1158/0008-5472.CAN-09-1760
Published: 28 October 2009
View article titled, Whole-Body <em>Sleeping Beauty</em> Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality
Open the PDF for Whole-Body <em>Sleeping Beauty</em> Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality in another window
Includes: Supplementary data
Journal Articles

A Dual Phosphoinositide-3-Kinase α/mTOR Inhibitor Cooperates with Blockade of Epidermal Growth Factor Receptor in PTEN-Mutant Glioma

Qi-Wen Fan, Christine K. Cheng, Theodore P. Nicolaides, Christopher S. Hackett, Zachary A. Knight, Kevan M. Shokat, William A. Weiss
Journal: Cancer Research
Cancer Res (2007) 67 (17): 7960–7965.
https://doi.org/10.1158/0008-5472.CAN-07-2154
Published: 05 September 2007
View article titled, A Dual Phosphoinositide-3-Kinase α/mTOR Inhibitor Cooperates with Blockade of Epidermal Growth Factor Receptor in <em>PTEN</em>-Mutant Glioma
Open the PDF for A Dual Phosphoinositide-3-Kinase α/mTOR Inhibitor Cooperates with Blockade of Epidermal Growth Factor Receptor in <em>PTEN</em>-Mutant Glioma in another window
Includes: Supplementary data
Journal Articles

Genome-wide Array CGH Analysis of Murine Neuroblastoma Reveals Distinct Genomic Aberrations which Parallel those in Human Tumors

Christopher S. Hackett, J. Graeme Hodgson, Mark E. Law, Jane Fridlyand, Kazutoyo Osoegawa, Pieter J. de Jong, Norma J. Nowak, Daniel Pinkel, Donna G. Albertson, Ajay Jain, Robert Jenkins, Joe W. Gray, William A. Weiss
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5266–5273.
Published: 18 September 2003
View article titled, Genome-wide Array CGH Analysis of Murine Neuroblastoma Reveals Distinct Genomic Aberrations which Parallel those in Human Tumors
Open the PDF for Genome-wide Array CGH Analysis of Murine Neuroblastoma Reveals Distinct Genomic Aberrations which Parallel those in Human Tumors in another window
Includes: Supplementary data