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Christopher P. Crum
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Journal Articles

Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer

Changxin Wan, Matthew P. Keany, Han Dong, Linah F. Al-Alem, Unnati M. Pandya, Suzan Lazo, Karsten Boehnke, Katherine N. Lynch, Rui Xu, Dominique T. Zarrella, Shengqing Gu, Paloma Cejas, Klothilda Lim, Henry W. Long, Kevin M. Elias, Neil S. Horowitz, Colleen M. Feltmate, Michael G. Muto, Michael J. Worley, Jr, Ross S. Berkowitz, Ursula A. Matulonis, Marisa R. Nucci, Christopher P. Crum, Bo R. Rueda, Myles Brown, Xiaole Shirley Liu, Sarah J. Hill
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (1): 158–173.
https://doi.org/10.1158/0008-5472.CAN-20-1674
Published: 04 January 2021
View article titled, Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer
Open the PDF for Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 368A: Functional assessment of DNA damage repair defects and the anti-tumor immune response in high grade serous ovarian cancers using patient-derived organoids

Sarah J. Hill, Patrick Lizotte, Neil S. Horowitz, Michael G. Muto, Michael J. Worley, Colleen M. Feltmate, Bose Kochupurakkal, Khanh T. Do, Panagiotis Konstantinopoulos, Marisa R. Nucci, Joyce F. Liu, Ursula A. Matulonis, Geoffrey I. Shapiro, Ross S. Berkowitz, Christopher P. Crum, Alan D. D'Andrea
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 368A.
https://doi.org/10.1158/1538-7445.AM2019-368A
Published: 01 July 2019
View article titled, Abstract 368A: Functional assessment of DNA damage repair defects and the anti-tumor immune response in high grade serous ovarian cancers using patient-derived organoids
Journal Articles

Abstract 4692: Relationships between somatic genomic alterations, tumor stage and progression-free survival in cervical cancer

Akinyemi I. Ojesina, Bradley Murray, Line Bjorge, Kathrine Woie, Camilla Krakstad, Lee Lichtenstein, Chandra Sekhar Pedamallu, Amaro Taylor-Weiner, Samuel S. Freeman, Andrew D. Cherniack, Michael S. Lawrence, Kristian Cibulskis, Scott L. Carter, Heather Walline, Thomas E. Carey, Olav K. Vintermyr, Bjorn Bertelsen, Christopher P. Crum, Gad Getz, Matthew Meyerson, Helga B. Salvesen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4692.
https://doi.org/10.1158/1538-7445.AM2014-4692
Published: 01 October 2014
View article titled, Abstract 4692: Relationships between somatic genomic alterations, tumor stage and progression-free survival in cervical cancer
Journal Articles

Abstract 4791: Serous cancer progenitor cells in the oviduct.

Gang Ning, Michael Herfs, Jonathan G. Bijron, Yasuke Yamamoto, Daniela Dinulescu, Frank D. McKeon, Christopher P. Crum, Wa Xian
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4791.
https://doi.org/10.1158/1538-7445.AM2013-4791
Published: 15 April 2013
View article titled, Abstract 4791: Serous cancer progenitor cells in the oviduct.
Journal Articles

Abstract 4604: Landscape of human and viral genomic alterations in cervical carcinomas.

Akinyemi I. Ojesina, Lee Lichtenstein, Lauren Ambrogio, Kristian Cibulskis, Samuel Freeman, Chandra Sekhar Pedamallu, Bjørn Bertelsen, Ivan Imaz, Karla Vazquez, Alberto Salido Guadarrama, Victor Treviño, Sandra Romero-Cordoba, Fujiko Duke, Bethany Kaplan, Iram Rodriguez, Magali Espinosa Castilla, Katherine Woie, Line Bjorge, Elisabeth Wik, Mari K. Halle, Erling Høivik, Camilla Krakstad, Gabriela Gómez Macías, María de Lourdes Garza Rodríguez, Jorge Vazquez, Carlos Rodea, Adrian Cravioto, Maria L. Cortes, Heidi Greulich, Christopher P. Crum, Lars Akslen, Hugo Barrera Saldaña, Jorge Melendez-Zajgla, Gad Getz, Helga B. Salvesen, Matthew L. Meyerson
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4604.
https://doi.org/10.1158/1538-7445.AM2013-4604
Published: 15 April 2013
View article titled, Abstract 4604: Landscape of human and viral genomic alterations in cervical carcinomas.
Journal Articles

Abstract 3292: A genetically engineered mouse model for high grade serous “ovarian” carcinoma arising in the fallopian tube

Ruth Perets, Katherine W. Muto, Jonathan G. Bijron, Chin T. Kenneth, Barish B. Poole, Christopher P. Crum, Daniela M. Dinulescu, Ronny Drapkin
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3292.
https://doi.org/10.1158/1538-7445.AM2012-3292
Published: 15 April 2012
View article titled, Abstract 3292: A genetically engineered mouse model for high grade serous “ovarian” carcinoma arising in the fallopian tube
Journal Articles

Abstract 3297: A cell of origin for cervical cancer

Michael Herfs, Yusuke Yamamoto, Anna R. Laury, Xia Wang, Margaret Mclaughlin-Druben, Marisa R. Nucci, Frank D. McKeon, Wa Xian, Christopher P. Crum
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3297.
https://doi.org/10.1158/1538-7445.AM2012-3297
Published: 15 April 2012
View article titled, Abstract 3297: A cell of origin for cervical cancer
Journal Articles

Abstract 114: Study of the high-grade ovarian cancer precursors in the oviduct

In Young Hwang, Ju Yuan, Gang Ning, Seok Wei Tay, Yusuke Yamamoto, Francesca Menghi, Edison Liu, Christopher P. Crum, Frank McKeon, Wa Xian
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 114.
https://doi.org/10.1158/1538-7445.AM2012-114
Published: 15 April 2012
View article titled, Abstract 114: Study of the high-grade ovarian cancer precursors in the oviduct
Journal Articles

Abstract 4328: Beta-catenin accelerates human papillomavirus type16 -E7 mediated cervical carcinogenesis in transgenic mice

Gülay Bulut, Shannon Fallen, Elspeth M. Beauchamp, Lauren E. Drebing, Junfeng Sun, Deborah L. Berry, Bhaskar Kallakury, Christopher P. Crum, Jeffrey A. Toretsky, Richard Schlegel, Aykut Üren
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4328.
https://doi.org/10.1158/1538-7445.AM2011-4328
Published: 15 April 2011
View article titled, Abstract 4328: Beta-catenin accelerates human papillomavirus type16 -E7 mediated cervical carcinogenesis in transgenic mice
Journal Articles

Abstract 104: PAX2 dysregulation in the fallopian tube and pelvic serous cancer

Gang Ning, Charles M. Quick, Ju Yuan, Alicia Tay, Anna R. Laury, Eleanor Y. Chen, Sara O. Vargas, Frank D. McKeon, Christopher P. Crum, Wa Xian
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 104.
https://doi.org/10.1158/1538-7445.AM2011-104
Published: 15 April 2011
View article titled, Abstract 104: PAX2 dysregulation in the fallopian tube and pelvic serous cancer
Journal Articles

Abstract 1995: Expression profiling of microdissected serous ovarian cancers and matched Fallopian tube identifies a gene signature of clinicopathologic importance

Vinod Vathipadiekal, Karishma K. Mehra, Sunghoon Kim, Christopher P. Crum, Xian Wa, Michael J. Birrer
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1995.
https://doi.org/10.1158/1538-7445.AM10-1995
Published: 15 April 2010
View article titled, Abstract 1995: Expression profiling of microdissected serous ovarian cancers and matched Fallopian tube identifies a gene signature of clinicopathologic importance
Journal Articles

Abstract 2054: A microRNA hypothesis for the precursor lesions of ovarian cancer

Kuan-Chun Huang, Yilan Zhou, Kathleen Hasselblatt, Junzheng Yang, Pui-Wah Choi, Wing-Ping Fong, Colleen Felmate, Michael G. Muto, Nelly Auersperg, Christopher P. Crum, Ross S. Berkowitz, Shu-Wing Ng
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2054.
https://doi.org/10.1158/1538-7445.AM10-2054
Published: 15 April 2010
View article titled, Abstract 2054: A microRNA hypothesis for the precursor lesions of ovarian cancer
Journal Articles

Human Epididymis Protein 4 (HE4) Is a Secreted Glycoprotein that Is Overexpressed by Serous and Endometrioid Ovarian Carcinomas

Ronny Drapkin, Hans Henning von Horsten, Yafang Lin, Samuel C. Mok, Christopher P. Crum, William R. Welch, Jonathan L. Hecht
Journal: Cancer Research
Cancer Res (2005) 65 (6): 2162–2169.
https://doi.org/10.1158/0008-5472.CAN-04-3924
Published: 21 March 2005
View article titled, Human Epididymis Protein 4 (HE4) Is a Secreted Glycoprotein that Is Overexpressed by Serous and Endometrioid Ovarian Carcinomas
Open the PDF for Human Epididymis Protein 4 (HE4) Is a Secreted Glycoprotein that Is Overexpressed by Serous and Endometrioid Ovarian Carcinomas in another window
Includes: Supplementary data
Journal Articles

NAD(P)H and Collagen as in Vivo Quantitative Fluorescent Biomarkers of Epithelial Precancerous Changes

Irene Georgakoudi, Brian C. Jacobson, Markus G. Müller, Ellen E. Sheets, Kamran Badizadegan, David L. Carr-Locke, Christopher P. Crum, Charles W. Boone, Ramachandra R. Dasari, Jacques Van Dam, Michael S. Feld
Journal: Cancer Research
Cancer Res (2002) 62 (3): 682–687.
Published: 01 February 2002
View article titled, NAD(P)H and Collagen as <em>in Vivo</em> Quantitative Fluorescent Biomarkers of Epithelial Precancerous Changes
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Journal Articles

Human Papillomavirus Type 16 E7 Oncoprotein-induced Abnormal Centrosome Synthesis Is an Early Event in the Evolving Malignant Phenotype

Stefan Duensing, Anette Duensing, Christopher P. Crum, Karl Münger
Journal: Cancer Research
Cancer Res (2001) 61 (6): 2356–2360.
Published: 03 March 2001
View article titled, Human Papillomavirus Type 16 E7 Oncoprotein-induced Abnormal Centrosome Synthesis Is an Early Event in the Evolving Malignant Phenotype
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Journal Articles

Binding by Immunoglobulin to the HPV-16-derived Proteins L1 and E4 in Cervical Secretions of Women with HPV-related Cervical Disease

Kimberly A. Snyder, Shannon R. Barber, Millie Symbula, Peyton T. Taylor, Christopher P. Crum, James K. Roche
Journal: Cancer Research
Cancer Res (1991) 51 (16): 4423–4429.
Published: 01 August 1991
View article titled, Binding by Immunoglobulin to the HPV-16-derived Proteins L1 and E4 in Cervical Secretions of Women with HPV-related Cervical Disease
Open the PDF for Binding by Immunoglobulin to the HPV-16-derived Proteins L1 and E4 in Cervical Secretions of Women with HPV-related Cervical Disease in another window