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Christopher J. Kemp
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Journal Articles

Pharmacologic Targeting of TFIIH Suppresses KRAS-Mutant Pancreatic Ductal Adenocarcinoma and Synergizes with TRAIL

Russell Moser, James Annis, Olga Nikolova, Cliff Whatcott, Kay Gurley, Eduardo Mendez, Kim Moran-Jones, Craig Dorrell, Rosalie C. Sears, Calvin Kuo, Haiyong Han, Andrew Biankin, Carla Grandori, Daniel D. Von Hoff, Christopher J. Kemp
Journal: Cancer Research
Cancer Res (2022) 82 (18): 3375–3393.
https://doi.org/10.1158/0008-5472.CAN-21-4222
Published: 16 September 2022
View article titled, Pharmacologic Targeting of TFIIH Suppresses KRAS-Mutant Pancreatic Ductal Adenocarcinoma and Synergizes with TRAIL
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Includes: Supplementary data
Journal Articles

Abstract 1603: Patient derived tumor organoids identify actionable targets in heavily pretreated metastatic breast cancer patients

Michael J. Churchill, Franz X. Schaub, Hallie A. Swan, Rachele Rosati, Fengting Yan, Reid C. Shaw, Kay E. Gurley, Robert L. Diaz, Shalini C. Pereira, Carla Grandori, Christopher J. Kemp, Vijayakrishna K. Gadi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1603.
https://doi.org/10.1158/1538-7445.AM2018-1603
Published: 01 July 2018
View article titled, Abstract 1603: Patient derived tumor organoids identify actionable targets in heavily pretreated metastatic breast cancer patients
Journal Articles

Abstract 1605: Personalization of cancer treatments with a CLIA-certified high-complexity and high-throughput drug sensitivity test

Hallie A. Swan, Michael J. Churchill, Rachele Rosati, Franz X. Schaub, Reid C. Shaw, Roland M. Watt, Eduardo Mendez, Christopher J. Kemp, Vijayakrishna K. Gadi, Stephanie A. Murphy, Brady Bernard, Robert L. Diaz, Shalini C. Pereira, Carla Grandori
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1605.
https://doi.org/10.1158/1538-7445.AM2018-1605
Published: 01 July 2018
View article titled, Abstract 1605: Personalization of cancer treatments with a CLIA-certified high-complexity and high-throughput drug sensitivity test
Journal Articles

Abstract 5249: Integrative analysis of transcriptomic, proteomic, and metabolomic data of Pten-knockout carcinogenic mouse prostate

Jinhui Zhang, Li Li, Sangyub Kim, LeeAnn Higgins, Yibin Deng, Christopher J. Kemp, Cheng Jiang, Junxuan Lu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5249.
https://doi.org/10.1158/1538-7445.AM2017-5249
Published: 01 July 2017
View article titled, Abstract 5249: Integrative analysis of transcriptomic, proteomic, and metabolomic data of <em>Pten</em>-knockout carcinogenic mouse prostate
Journal Articles

Abstract A34: Arf suppresses the growth and progression of Kras-driven lung tumors

Stephanie E. Busch, Kay E. Gurley, Russell D. Moser, Karen S. Kelly-Spratt, Christopher J. Kemp
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): A34.
https://doi.org/10.1158/1538-7445.FBCR11-A34
Published: 28 October 2014
View article titled, Abstract A34: Arf suppresses the growth and progression of Kras-driven lung tumors
Journal Articles

Abstract PR11: Doxorubicin enhances nucleosome turnover around active gene promoters

Fan Yang, Christopher J. Kemp, Steven Henikoff
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): PR11.
https://doi.org/10.1158/1538-7445.CEC13-PR11
Published: 13 May 2014
View article titled, Abstract PR11: Doxorubicin enhances nucleosome turnover around active gene promoters
Journal Articles

MiR-96 Downregulates REV1 and RAD51 to Promote Cellular Sensitivity to Cisplatin and PARP Inhibition

Yemin Wang, Jen-Wei Huang, Philamer Calses, Christopher J. Kemp, Toshiyasu Taniguchi
Journal: Cancer Research
Cancer Res (2012) 72 (16): 4037–4046.
https://doi.org/10.1158/0008-5472.CAN-12-0103
Published: 14 August 2012
View article titled, MiR-96 Downregulates REV1 and RAD51 to Promote Cellular Sensitivity to Cisplatin and PARP Inhibition
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Includes: Supplementary data
Journal Articles

Abstract 118: CTCF, a master epigenetic regulator, is a haploinsufficient tumor suppressor gene in multiple cell lineages

James M. Moore, Russell Moser, Leslie Smith, Kay Gurley, Denny Liggett, Galina Filippova, Christopher J. Kemp
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 118.
https://doi.org/10.1158/1538-7445.AM2012-118
Published: 15 April 2012
View article titled, Abstract 118: CTCF, a master epigenetic regulator, is a haploinsufficient tumor suppressor gene in multiple cell lineages
Journal Articles

Tumor Microenvironment–Derived Proteins Dominate the Plasma Proteome Response during Breast Cancer Induction and Progression

Sharon J. Pitteri, Karen S. Kelly-Spratt, Kay E. Gurley, Jacob Kennedy, Tina Busald Buson, Alice Chin, Hong Wang, Qing Zhang, Chee-Hong Wong, Lewis A. Chodosh, Peter S. Nelson, Samir M. Hanash, Christopher J. Kemp
Journal: Cancer Research
Cancer Res (2011) 71 (15): 5090–5100.
https://doi.org/10.1158/0008-5472.CAN-11-0568
Published: 28 July 2011
View article titled, Tumor Microenvironment–Derived Proteins Dominate the Plasma Proteome Response during Breast Cancer Induction and Progression
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Includes: Supplementary data
Journal Articles

Abstract 3166: Lung cancer bio-signatures in plasma based on the analysis of mouse models

Ayumu Taguchi, Katerina Politi, Sharon J. Pitteri, William W. Lockwood, Vitor M. Faça, Julien Sage, Christopher J. Kemp, Harold E. Varmus, Samir M. Hanash
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3166.
https://doi.org/10.1158/1538-7445.AM2011-3166
Published: 15 April 2011
View article titled, Abstract 3166: Lung cancer bio-signatures in plasma based on the analysis of mouse models
Journal Articles

Metastasis Suppressor Function of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand-R in Mice: Implications for TRAIL-Based Therapy in Humans?

Anne Grosse-Wilde, Christopher J. Kemp
Journal: Cancer Research
Cancer Res (2008) 68 (15): 6035–6037.
https://doi.org/10.1158/0008-5472.CAN-08-0078
Published: 01 August 2008
View article titled, Metastasis Suppressor Function of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand-R in Mice: Implications for TRAIL-Based Therapy in Humans?
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Journal Articles

Analysis of TRAIL-receptor-deficient mice in a two-stage skin tumorigenesis model reveals a role for TRAIL-receptor in suppression of metastasis formation

Anne Grosse-Wilde, Shawn L. Bailey, Erich F. Greiner, Kay E. Gurley, Claudia Rappl, Johannes F. Coy, Peter H. Krammer, Gunther Schutz, Christopher J. Kemp, Henning Walczak
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 562.
Published: 15 April 2006
View article titled, Analysis of TRAIL-receptor-deficient mice in a two-stage skin tumorigenesis model reveals a role for TRAIL-receptor in suppression of metastasis formation
Journal Articles

p53 Induction and Apoptosis in Response to Radio- and Chemotherapy in Vivo Is Tumor-Type-dependent

Christopher J. Kemp, Shaoli Sun, Kay E. Gurley
Journal: Cancer Research
Cancer Res (2001) 61 (1): 327–332.
Published: 01 January 2001
View article titled, p53 Induction and Apoptosis in Response to Radio- and Chemotherapy <em>in Vivo</em> Is Tumor-Type-dependent
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Journal Articles

DNA Double-Strand Breaks, p53, and Apoptosis during Lymphomagenesis in scid/scid Mice

Kay E. Gurley, Khoa Vo, Christopher J. Kemp
Journal: Cancer Research
Cancer Res (1998) 58 (14): 3111–3115.
Published: 01 July 1998
View article titled, DNA Double-Strand Breaks, p53, and Apoptosis during Lymphomagenesis in <em>scid/scid</em> Mice
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Journal Articles

Spontaneous and Ionizing Radiation-induced Chromosomal Abnormalities in p53-deficient Mice

Simon D. Bouffler, Christopher J. Kemp, Allan Balmain, Roger Cox
Journal: Cancer Research
Cancer Res (1995) 55 (17): 3883–3889.
Published: 01 September 1995
View article titled, Spontaneous and Ionizing Radiation-induced Chromosomal Abnormalities in <em>p53</em>-deficient Mice
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Journal Articles

Lack of Transforming Growth Factor-β1 Expression in Benign Skin Tumors of p53null Mice Is Prognostic for a High Risk of Malignant Conversion

Wei Cui, Christopher J. Kemp, Elizabeth Duffie, Allan Balmain, Rosemary J. Akhurst
Journal: Cancer Research
Cancer Res (1994) 54 (22): 5831–5836.
Published: 01 November 1994
View article titled, Lack of Transforming Growth Factor-β<sub>1</sub> Expression in Benign Skin Tumors of <em>p53</em><sup>null</sup> Mice Is Prognostic for a High Risk of Malignant Conversion
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Journal Articles

The Role of p53 in Spontaneous and Radiation-induced Apoptosis in the Gastrointestinal Tract of Normal and p53-deficient Mice

Anita J. Merritt, Christopher S. Potten, Christopher J. Kemp, John A. Hickman, Allan Balmain, David P. Lane, Peter A. Hall
Journal: Cancer Research
Cancer Res (1994) 54 (3): 614–617.
Published: 01 February 1994
View article titled, The Role of <em>p53</em> in Spontaneous and Radiation-induced Apoptosis in the Gastrointestinal Tract of Normal and p53-deficient Mice
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Journal Articles

Allelotype Analysis of Mouse Skin Tumors Using Polymorphic Microsatellites: Sequential Genetic Alterations on Chromosomes 6, 7, and 11

Christopher J. Kemp, Frances Fee, Allan Balmain
Journal: Cancer Research
Cancer Res (1993) 53 (24): 6022–6027.
Published: 01 December 1993
View article titled, Allelotype Analysis of Mouse Skin Tumors Using Polymorphic Microsatellites: Sequential Genetic Alterations on Chromosomes 6, 7, and 11
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Journal Articles

Genetic Variation in Liver Tumor Susceptibility, Plasma Testosterone Levels, and Androgen Receptor Binding in Six Inbred Strains of Mice

Christopher J. Kemp, Norman R. Drinkwater
Journal: Cancer Research
Cancer Res (1989) 49 (18): 5044–5047.
Published: 01 September 1989
View article titled, Genetic Variation in Liver Tumor Susceptibility, Plasma Testosterone Levels, and Androgen Receptor Binding in Six Inbred Strains of Mice
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