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Abstract PS17-05: Relationship between body mass index and tumor subtype by menopausal status: An analysis in women with lobular carcinoma of the breast

Harriet Rothschild, Laura Esserman, Christopher Benz, Rita Mukhtar

Cancer Res (2021) 81 (4_Supplement): PS17-05.

DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS17-05

Published: 15 February 2021

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Journal Articles

Abstract 3850: The potent catalytic p300HAT inhibitor A-485 induces rapid decay and reduction in breast cancer ERBB2 mRNA expression

Gary K. Scott, Jacob Rose, Lei Wei, Birgit Schilling, Christopher Benz

Cancer Res (2019) 79 (13_Supplement): 3850.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3850

Published: 01 July 2019

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Journal Articles

Abstract 4773: Knockdown of the p300 histone acetylase stimulates the rapid and selective decay of ERBB2 mRNA as induced by class 1 histone deacetylase inhibitors

Gary K. Scott, Lei Wei, Mariah Alejo, Jacob Rose, Birgit Schilling, Christopher Benz

Cancer Res (2018) 78 (13_Supplement): 4773.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4773

Published: 01 July 2018

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Journal Articles

Abstract 4864: Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

Nicholas Schaum, Christopher Wiley, Fatouma Almirah, Jose A. Lopez-Dominguez, Gary Scott, Christopher Benz, Judith Campisi, Albert R. Davalos

Cancer Res (2018) 78 (13_Supplement): 4864.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4864

Published: 01 July 2018

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Journal Articles

Abstract 4729: Class-selective histone deacetylase inhibitors differentially promote translation-dependent HER2 transcript decay in HER2-positive breast cancer cells

Gary K. Scott, Katya Frazier, Sadaf Malik, Mariah Alejo, Birgit Schilling, Christopher Benz

Cancer Res (2016) 76 (14_Supplement): 4729.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4729

Published: 15 July 2016

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Journal Articles

Abstract B1-38: PARADIGM-SHIFT: Predicts the functional impact of ‘driver modules’ in multiple cancers using pathway impact analysis

Sam Ng, Christopher Benz, David Haussler, Joshua M. Stuart

Cancer Res (2015) 75 (22_Supplement_2): B1-38.

DOI: https://doi.org/10.1158/1538-7445.COMPSYSBIO-B1-38

Published: 15 November 2015

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Journal Articles

Abstract 5402: A new anticancer strategy based on inhibiting mitochondrial proline dehydrogenase (PRODH) and exploiting synthetic lethal interactions with p53 restoration and/or glutaminase (GLS1) inhibition

Gary K. Scott, Justine Rutter, Katya Frazier, Daniel Rothschild, Christina Yau, Christopher Benz

Cancer Res (2015) 75 (15_Supplement): 5402.

DOI: https://doi.org/10.1158/1538-7445.AM2015-5402

Published: 01 August 2015

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Journal Articles

Abstract 1271: MDM2 small molecule inhibitors synergize with chemotherapeutics to attenuate senescence-driven inflammatory secretion

Nicholas Schaum, Fatouma Almirah, Gary Scott, Christopher Benz, Judith Campisi, Albert R. Davalos

Cancer Res (2015) 75 (15_Supplement): 1271.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1271

Published: 01 August 2015

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Journal Articles

Abstract 4555: Inhibition of CDK1/2 but not CDK4/6 cooperates with tamoxifen to induce apoptosis

Gary K. Scott, Daniel Rothschild, Ravneet Kaur, Christopher Benz

Cancer Res (2014) 74 (19_Supplement): 4555.

DOI: https://doi.org/10.1158/1538-7445.AM2014-4555

Published: 01 October 2014

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Journal Articles

Abstract 1813: FOXM1 target genes associated with cell cycle regulation predict breast cancer metastatic outcome.

Christina Yau, Laurence Meyer, Stephen Benz, Charles Vaske, Gary Scott, Brian Egan, Paul Labhart, Elizabeth Mitchell, Nader Pourmand, Christopher Benz

Cancer Res (2013) 73 (8_Supplement): 1813.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1813

Published: 15 April 2013

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Journal Articles

Abstract 2985: Predicting the impact of mutations in cancer using an integrated pathway approach

Sam Ng, Janita Thusberg, Stephen Benz, Charles Vaske, Kyle Ellrott, Jing Zhu, Christina Yau, Eric Collisson, Sean Mooney, Christopher Benz, David Haussler, Joshua Stuart

Cancer Res (2012) 72 (8_Supplement): 2985.

DOI: https://doi.org/10.1158/1538-7445.AM2012-2985

Published: 15 April 2012

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Journal Articles

Abstract 643: Therapeutically targeting eIF4E overexpressing breast cancers destined for early metastatic relapse

Christina Yau, Gary Scott, Rachel Puckett, Yamei Zhou, Christopher Benz

Cancer Res (2010) 70 (8_Supplement): 643.

DOI: https://doi.org/10.1158/1538-7445.AM10-643

Published: 15 April 2010

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Journal Articles

Abstract #2422: Prognostic gene candidates for early stage hormone receptor-negative and triple-negative breast cancer

Christina Yau, Fred Waldman, John Sninsky, Dan Moore, Eugene Fan, Laura Esserman, Christopher Benz

Cancer Res (2009) 69 (9_Supplement): 2422.

Published: 01 May 2009

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Journal Articles

Abstract #2432: Differential association of tumor proliferation and oxidative stress with age-at-diagnosis in estrogen receptor (ER)-positive and ER-negative breast cancers

Christina Yau, Christopher Benz

Cancer Res (2009) 69 (9_Supplement): 2432.

Published: 01 May 2009

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Journal Articles

Abstract #2874: Screening and validation of polyribosomal targets mediating histone deacetylase inhibitor (HDACi) accelerated ERBB2 transcript decay.

Gary Scott, Jason Held, Bianca Gabriel, Rachel Puckett, Christopher Benz

Cancer Res (2009) 69 (9_Supplement): 2874.

Published: 01 May 2009

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Journal Articles

Oxidant and estrogen responsive gene signature in ER-positive primary breast cancers associated with aggressive growth pathways and reduced patient survival.

Christina Yau, Christopher Benz

Cancer Res (2008) 68 (9_Supplement): 1659.

Published: 01 May 2008

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Journal Articles

Lysine-48 and lysine-63 linked polyubiquitination of ERBB2 associated with proteasome and lysosome trafficking and receptor degradation

Corina Marx, Jason Held, Bradford Gibson, Christopher Benz

Cancer Res (2008) 68 (9_Supplement): 3503.

Published: 01 May 2008

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Journal Articles

Ligand dependent induction of phospho-serine 294 in the hinge region of estrogen receptor alpha within human breast cancer cells

David Britton, Jason Held, Gary Scott, Birgit Schilling, Christian Atsriku, Michael Baldwin, Bradford Gibson, Christopher Benz

Cancer Res (2008) 68 (9_Supplement): 5458.

Published: 01 May 2008

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Journal Articles

Mutations in TP53 and associated genomic abnormalities are dependent on breast cancer estrogen receptor status and patient age

Vita Fedele, Jane Fridlyand, Ritu Roydasgupta, Stefania Tommasi, Angelo Paradiso, Donna Albertson, Christopher Benz

Cancer Res (2007) 67 (9_Supplement): 2962.

Published: 01 May 2007

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Journal Articles

NFκB/AP-1 upregulated genes VEGF, PLAU and CCND1 identify ER-positive node-negative breast cancers at risk for relapse on tamoxifen

Christina Yau, Yamei Zhou, Joe Gray, Karen Chew, Shanaz Dairkee, Dan Moore, Urs Eppenberger, Serenella Eppenberger-Castori, Christopher Benz

Cancer Res (2007) 67 (9_Supplement): 2434.

Published: 01 May 2007

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NARROW

Abstract PS17-05: Relationship between body mass index and tumor subtype by menopausal status: An analysis in women with lobular carcinoma of the breast

Abstract 3850: The potent catalytic p300HAT inhibitor A-485 induces rapid decay and reduction in breast cancer ERBB2 mRNA expression

Abstract 4773: Knockdown of the p300 histone acetylase stimulates the rapid and selective decay of ERBB2 mRNA as induced by class 1 histone deacetylase inhibitors

Abstract 4864: Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

Abstract 4729: Class-selective histone deacetylase inhibitors differentially promote translation-dependent HER2 transcript decay in HER2-positive breast cancer cells

Abstract B1-38: PARADIGM-SHIFT: Predicts the functional impact of ‘driver modules’ in multiple cancers using pathway impact analysis

Abstract 5402: A new anticancer strategy based on inhibiting mitochondrial proline dehydrogenase (PRODH) and exploiting synthetic lethal interactions with p53 restoration and/or glutaminase (GLS1) inhibition

Abstract 1271: MDM2 small molecule inhibitors synergize with chemotherapeutics to attenuate senescence-driven inflammatory secretion

Abstract 4555: Inhibition of CDK1/2 but not CDK4/6 cooperates with tamoxifen to induce apoptosis

Abstract 1813: FOXM1 target genes associated with cell cycle regulation predict breast cancer metastatic outcome.

Abstract 2985: Predicting the impact of mutations in cancer using an integrated pathway approach

Abstract 643: Therapeutically targeting eIF4E overexpressing breast cancers destined for early metastatic relapse

Abstract #2422: Prognostic gene candidates for early stage hormone receptor-negative and triple-negative breast cancer

Abstract #2432: Differential association of tumor proliferation and oxidative stress with age-at-diagnosis in estrogen receptor (ER)-positive and ER-negative breast cancers

Abstract #2874: Screening and validation of polyribosomal targets mediating histone deacetylase inhibitor (HDACi) accelerated ERBB2 transcript decay.

Oxidant and estrogen responsive gene signature in ER-positive primary breast cancers associated with aggressive growth pathways and reduced patient survival.

Lysine-48 and lysine-63 linked polyubiquitination of ERBB2 associated with proteasome and lysosome trafficking and receptor degradation

Ligand dependent induction of phospho-serine 294 in the hinge region of estrogen receptor alpha within human breast cancer cells

Mutations in TP53 and associated genomic abnormalities are dependent on breast cancer estrogen receptor status and patient age

NFκB/AP-1 upregulated genes VEGF, PLAU and CCND1 identify ER-positive node-negative breast cancers at risk for relapse on tamoxifen

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