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Christopher A. French
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Journal Articles

EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes

Yeying Huang, R. Taylor Durall, Nhi M. Luong, Hans J. Hertzler, Julianna Huang, Prafulla C. Gokhale, Brittaney A. Leeper, Nicole S. Persky, David E. Root, Praju V. Anekal, Paula D.L.M. Montero Llopis, Clement N. David, Jeffery L. Kutok, Alejandra Raimondi, Karan Saluja, Jia Luo, Cynthia A. Zahnow, Biniam Adane, Kimberly Stegmaier, Catherine E. Hawkins, Christopher Ponne, Quan Le, Geoffrey I. Shapiro, Madeleine E. Lemieux, Kyle P. Eagen, Christopher A. French
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3956–3973.
https://doi.org/10.1158/0008-5472.CAN-23-1475
Published: 01 December 2023
View article titled, EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes
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Includes: Supplementary data
Journal Articles

The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma

R. Taylor Durall, Julianna Huang, Luke Wojenski, Yeying Huang, Prafulla C. Gokhale, Brittaney A. Leeper, Joshua O. Nash, Pedro L. Ballester, Scott Davidson, Adam Shlien, Emmanuel Sotirakis, Fabien Bertaux, Vincent Dubus, Jia Luo, Catherine J. Wu, Derin B. Keskin, Kyle P. Eagen, Geoffrey I. Shapiro, Christopher A. French
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3846–3860.
https://doi.org/10.1158/0008-5472.CAN-23-2545
Published: 01 December 2023
View article titled, The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma
Open the PDF for The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 2487: Novel ZNF-fusions in NUT carcinoma

Hitoshi Shiota, Janine E. Elya, Kristina Danga, Kelly Becht, Pauline Chou, Artyom A. Alekseyenko, Valentina Nardi, Christopher A. French
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2487.
https://doi.org/10.1158/1538-7445.AM2018-2487
Published: 01 July 2018
View article titled, Abstract 2487: Novel ZNF-fusions in NUT carcinoma
Journal Articles

Abstract 2655: Oncogenic chromatin factors drive cell type-specific transcription within megadomains in NUT midline carcinoma

Mitzi I. Kuroda, Artyom A. Alekseyenko, Erica M. Walsh, Xin Wang, Adlai Grayson, Peter T. Hsi, Peter V. Kharchenko, Christopher A. French
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2655.
https://doi.org/10.1158/1538-7445.AM2016-2655
Published: 15 July 2016
View article titled, Abstract 2655: Oncogenic chromatin factors drive cell type-specific transcription within megadomains in NUT midline carcinoma
Journal Articles

Activation of SOX2 Expression by BRD4-NUT Oncogenic Fusion Drives Neoplastic Transformation in NUT Midline Carcinoma

Ranran Wang, Wei Liu, Christine M. Helfer, James E. Bradner, Jason L. Hornick, Susan M. Janicki, Christopher A. French, Jianxin You
Journal: Cancer Research
Cancer Res (2014) 74 (12): 3332–3343.
https://doi.org/10.1158/0008-5472.CAN-13-2658
Published: 12 June 2014
View article titled, Activation of <em>SOX2</em> Expression by BRD4-NUT Oncogenic Fusion Drives Neoplastic Transformation in NUT Midline Carcinoma
Open the PDF for Activation of <em>SOX2</em> Expression by BRD4-NUT Oncogenic Fusion Drives Neoplastic Transformation in NUT Midline Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 2318: BET bromodomain inhibitors for cancer therapy

Jun Qi, Panagis Filippakopoulos, Michael McKeown, Katharin L. Shaw, William B. Smith, Christopher A. French, Andrew L. Kung, Stefan Knapp, James E. Bradner
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2318.
https://doi.org/10.1158/1538-7445.AM2011-2318
Published: 15 April 2011
View article titled, Abstract 2318: BET bromodomain inhibitors for cancer therapy
Journal Articles

Differentiation of NUT Midline Carcinoma by Epigenomic Reprogramming

Brian E. Schwartz, Matthias D. Hofer, Madeleine E. Lemieux, Daniel E. Bauer, Michael J. Cameron, Nathan H. West, Elin S. Agoston, Nicolas Reynoird, Saadi Khochbin, Tan A. Ince, Amanda Christie, Katherine A. Janeway, Sara O. Vargas, Antonio R. Perez-Atayde, Jon C. Aster, Stephen E. Sallan, Andrew L. Kung, James E. Bradner, Christopher A. French
Journal: Cancer Research
Cancer Res (2011) 71 (7): 2686–2696.
https://doi.org/10.1158/0008-5472.CAN-10-3513
Published: 31 March 2011
View article titled, Differentiation of NUT Midline Carcinoma by Epigenomic Reprogramming
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Includes: Supplementary data
Journal Articles

BRD4-NUT Fusion Oncogene: A Novel Mechanism in Aggressive Carcinoma

Christopher A. French, Isao Miyoshi, Ichiro Kubonishi, Holcombe E. Grier, Antonio R. Perez-Atayde, Jonathan A. Fletcher
Journal: Cancer Research
Cancer Res (2003) 63 (2): 304–307.
Published: 15 January 2003
View article titled, <em>BRD4-NUT</em> Fusion Oncogene: <subtitle>A Novel Mechanism in Aggressive Carcinoma</subtitle>
Open the PDF for <em>BRD4-NUT</em> Fusion Oncogene: <subtitle>A Novel Mechanism in Aggressive Carcinoma</subtitle> in another window