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Christophe Meille
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Journal Articles

Abstract CT009: Results of a dose- and regimen-finding Phase Ib study of HDM201 in combination with ribociclib in patients with locally advanced or metastatic liposarcoma

Albiruni Abdul Razak, Sebastian Bauer, Jean-Yves Blay, Richard Quek, Cristina Suárez, Chia-Chi Lin, Marie L. Hütter-Krönke, Ricardo Cubedo, Stephane Ferretti, Christophe Meille, Ensar Halilovic, Giorgia Clementi, Maria Santos-Rosa, Nelson Guerreiro, Astrid Jullion, Claire Fabre, Antoine Italiano
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT009.
https://doi.org/10.1158/1538-7445.AM2018-CT009
Published: 01 July 2018
View articletitled, Abstract CT009: Results of a dose- and regimen-finding Phase Ib study of HDM201 in combination with ribociclib in patients with locally advanced or metastatic liposarcoma
Journal Articles

Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy

Joseph Ciccolini, Dominique Barbolosi, Christophe Meille, Aurélie Lombard, Cindy Serdjebi, Sarah Giacometti, Laetitia Padovani, Eddy Pasquier, Nicolas André
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4723–4733.
https://doi.org/10.1158/0008-5472.CAN-16-3130
Published: 31 August 2017
View articletitled, Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy
Open the PDF for Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract CT150: Optimizing the therapeutic index of HDM2 inhibition: Results from a dose- and regimen-finding Phase I study of NVP-HDM201 in pts with TP53 wt advanced tumors

David M. Hyman, Manik Chatterjee, Filip de Vos, Chia-Chi Lin, Cristina Suárez, David Tai, Philippe Cassier, Noboru Yamamoto, Vincent A. de Weger, Sébastien Jeay, Christophe Meille, Ensar Halilovic, Luisa Mariconti, Matthieu Klopfenstein, Nelson Guerreiro, Rajkumar Radhakrishnan, Emil T. Kuriakose, Sebastian Bauer
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT150.
https://doi.org/10.1158/1538-7445.AM2017-CT150
Published: 01 July 2017
View articletitled, Abstract CT150: Optimizing the therapeutic index of HDM2 inhibition: Results from a dose- and regimen-finding Phase I study of NVP-HDM201 in pts with TP53 wt advanced tumors
Journal Articles

Abstract CT152: Phase I dose- and regimen-finding study of NVP-HDM201 in pts with advanced TP53 wt acute leukemias

Eytan Stein, Joerg Chromik, Daniel J. DeAngelo, Manik Chatterjee, Richard Noppeney, Filip de Vos, Hironobu Minami, Sébastien Jeay, Christophe Meille, Ensar Halilovic, Luisa Mariconti, Matthieu Klopfenstein, Nelson Guerreiro, Rajkumar Radhakrishnan, Emil T. Kuriakose, Cecilia Carpio
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT152.
https://doi.org/10.1158/1538-7445.AM2017-CT152
Published: 01 July 2017
View articletitled, Abstract CT152: Phase I dose- and regimen-finding study of NVP-HDM201 in pts with advanced TP53 wt acute leukemias
Journal Articles

Abstract CT154: Optimization of the dose and schedule of an HDM2 inhibitor NVP-HDM201 in a first-in-human Phase I study using a mechanism-based PK/PD model

Christophe Meille, Nelson Guerreiro, Astrid Jullion, Sebastian Bauer, Manik Chatterjee, Filip de Vos, Chia-Chi Lin, Cristina Suárez Rodríguez, David Tai, Philippe Cassier, Noboru Yamamoto, Vincent A. de Weger, Matthieu Klopfenstein, Luisa Mariconti, Emil T. Kuriakose, David M. Hyman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT154.
https://doi.org/10.1158/1538-7445.AM2017-CT154
Published: 01 July 2017
View articletitled, Abstract CT154: Optimization of the dose and schedule of an HDM2 inhibitor NVP-HDM201 in a first-in-human Phase I study using a mechanism-based PK/PD model
Journal Articles

Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy

Raphael Serre, Sebastien Benzekry, Laetitia Padovani, Christophe Meille, Nicolas André, Joseph Ciccolini, Fabrice Barlesi, Xavier Muracciole, Dominique Barbolosi
Journal: Cancer Research
Cancer Res (2016) 76 (17): 4931–4940.
https://doi.org/10.1158/0008-5472.CAN-15-3567
Published: 31 August 2016
View articletitled, Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy
Open the PDF for Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy in another window
Includes: Supplementary data