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Journal Articles

Abstract 2652: NDI-101150 is a potent and highly selective HPK1 inhibitor that both synergizes with and differentiates from anti-PD1 immune checkpoint blockade

David Ciccone, Fu-Shan Kuo, Scott Daigle, Neelu Kaila, Gene Yau, Mark Carlson, Denise Levasseur, Bhaskar Srivastava, Frank G. Basile, Christine Loh

Cancer Res (2024) 84 (6_Supplement): 2652.

https://doi.org/10.1158/1538-7445.AM2024-2652

Published: 22 March 2024

View article titled, Abstract 2652: NDI-101150 is a potent and highly selective HPK1 inhibitor that both synergizes with and differentiates from anti-PD1 immune checkpoint blockade

Journal Articles

Abstract 2064: Targeting Cblb-Notch1 axis as a novel strategy for cancer immunotherapy

Giulia Monticone, Fred Csibi, Silvana Leit, Jermaine E. Austin, Deniz A. Ucar, Fokhrul M. Hossain, Samarpan Majumder, Barbara A. Osborne, Christine Loh, Lucio Miele

Cancer Res (2022) 82 (12_Supplement): 2064.

https://doi.org/10.1158/1538-7445.AM2022-2064

Published: 15 June 2022

View article titled, Abstract 2064: Targeting Cblb-Notch1 axis as a novel strategy for cancer immunotherapy

Journal Articles

Abstract 589: Discovery of NTX-001, a potent Cbl-b inhibitor with antitumor activity in syngeneic models

Fred Csibi-Levin, Silvana Leit, David L. Laughton, Tom Baker, Suzanne L. Jacques, Beth Browning, Angela V. Toms, Samantha Garside, Simon D'Archivio, Katarzyna Kopycka, Xiaohua Zhu, Allan M. Jordan, Stuart Thomson, Christine Loh, Peter Tummino, David N. Ciccone

Cancer Res (2022) 82 (12_Supplement): 589.

https://doi.org/10.1158/1538-7445.AM2022-589

Published: 15 June 2022

View article titled, Abstract 589: Discovery of NTX-001, a potent Cbl-b inhibitor with antitumor activity in syngeneic models

Journal Articles

Abstract 1649: Mechanistic understanding of HPK1 inhibition on enhanced human T cell activation and tumor immunity in a syngeneic model

David Ciccone, Vad Lazari, Ian Linney, Michael Briggs, Samantha Carreiro, Christine Loh, Peter Tummino, Joshua McElwee, Alan Collis, Neelu Kaila

Cancer Res (2021) 81 (13_Supplement): 1649.

https://doi.org/10.1158/1538-7445.AM2021-1649

Published: 01 July 2021

View article titled, Abstract 1649: Mechanistic understanding of HPK1 inhibition on enhanced human T cell activation and tumor immunity in a syngeneic model

Journal Articles

Abstract 942: HPK1, hematopoietic progenitor kinase 1, is a promising therapeutic target for cancer immunotherapy

David Ciccone, Jennifer Rocnik, Vad Lazari, Ian Linney, Michael Briggs, Alan Collis, Christine Loh, Mark Ashwell, John Montana, Peter Tummino, Neelu Kaila

Cancer Res (2020) 80 (16_Supplement): 942.

https://doi.org/10.1158/1538-7445.AM2020-942

Published: 15 August 2020

View article titled, Abstract 942: HPK1, hematopoietic progenitor kinase 1, is a promising therapeutic target for cancer immunotherapy

Journal Articles

Abstract LB-272: KYM-001, a first-in-class oral IRAK4 protein degrader, induces tumor regression in xenograft models of MYD88-mutant ABC DLBCL alone and in combination with BTK inhibition

Cancer Res (2019) 79 (13_Supplement): LB-272.

https://doi.org/10.1158/1538-7445.AM2019-LB-272

Published: 01 July 2019

View article titled, Abstract LB-272: KYM-001, a first-in-class oral IRAK4 protein degrader, induces tumor regression in xenograft models of MYD88-mutant ABC DLBCL alone and in combination with BTK inhibition

Journal Articles

Effect of Hyperthermia on the Action of cis-Diamminedichloroplatinum(II), Rhodamine 123₂ [Tetrachloroplatinum(II)], Rhodamine 123, and Potassium Tetrachloroplatinate in Vitro and in Vivo

Terence S. Herman, Beverly A. Teicher, Victor Chan, Laura S. Collins, Mark E. Kaufmann, Christine Loh

Cancer Res (1988) 48 (9): 2335–2341.

Published: 01 May 1988

View article titled, Effect of Hyperthermia on the Action of cis-Diamminedichloroplatinum(II), Rhodamine 1232 [Tetrachloroplatinum(II)], Rhodamine 123, and Potassium Tetrachloroplatinate in Vitro and in Vivo

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Abstract 2652: NDI-101150 is a potent and highly selective HPK1 inhibitor that both synergizes with and differentiates from anti-PD1 immune checkpoint blockade

Abstract 2064: Targeting Cblb-Notch1 axis as a novel strategy for cancer immunotherapy

Abstract 589: Discovery of NTX-001, a potent Cbl-b inhibitor with antitumor activity in syngeneic models

Abstract 1649: Mechanistic understanding of HPK1 inhibition on enhanced human T cell activation and tumor immunity in a syngeneic model

Abstract 942: HPK1, hematopoietic progenitor kinase 1, is a promising therapeutic target for cancer immunotherapy

Abstract LB-272: KYM-001, a first-in-class oral IRAK4 protein degrader, induces tumor regression in xenograft models of MYD88-mutant ABC DLBCL alone and in combination with BTK inhibition

Effect of Hyperthermia on the Action of cis-Diamminedichloroplatinum(II), Rhodamine 123₂ [Tetrachloroplatinum(II)], Rhodamine 123, and Potassium Tetrachloroplatinate in Vitro and in Vivo

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AACR Journals

Abstract 2652: NDI-101150 is a potent and highly selective HPK1 inhibitor that both synergizes with and differentiates from anti-PD1 immune checkpoint blockade

Abstract 2064: Targeting Cblb-Notch1 axis as a novel strategy for cancer immunotherapy

Abstract 589: Discovery of NTX-001, a potent Cbl-b inhibitor with antitumor activity in syngeneic models

Abstract 1649: Mechanistic understanding of HPK1 inhibition on enhanced human T cell activation and tumor immunity in a syngeneic model

Abstract 942: HPK1, hematopoietic progenitor kinase 1, is a promising therapeutic target for cancer immunotherapy

Abstract LB-272: KYM-001, a first-in-class oral IRAK4 protein degrader, induces tumor regression in xenograft models of MYD88-mutant ABC DLBCL alone and in combination with BTK inhibition

Effect of Hyperthermia on the Action of cis-Diamminedichloroplatinum(II), Rhodamine 1232 [Tetrachloroplatinum(II)], Rhodamine 123, and Potassium Tetrachloroplatinate in Vitro and in Vivo

Email alerts

AACR Journals

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Effect of Hyperthermia on the Action of cis-Diamminedichloroplatinum(II), Rhodamine 123₂ [Tetrachloroplatinum(II)], Rhodamine 123, and Potassium Tetrachloroplatinate in Vitro and in Vivo