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Ching C. Lau
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Journal Articles

Abstract 634: Targeting metastatic brain germinoma using PDOX tumor models with sequential metastases

Shiying Huang, Sekar Karthik, Jack M Su, Qi Lin, YuChen Du, Ching C Lau, Adesina Adekunle, Angela Major, Kam-Man Hui, M. Tarek Elghetany, Xiaonan Li, Wan-Yee Teo
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 634.
https://doi.org/10.1158/1538-7445.AM2021-634
Published: 01 July 2021
View article titled, Abstract 634: Targeting metastatic brain germinoma using PDOX tumor models with sequential metastases
Journal Articles

Abstract LB-307: Translational and mechanistic implications of osteosarcoma genomics: A TARGET report

Paul S. Meltzer, Sean Davis, Jack Zhu, Yonghong Wang, Sven Bilke, Joshua Waterfall, Robert Walker, Marbin Pineda, Yuan Jiang, Sharon Savage, Lisa Mirabello, Tsz-Kwong Man, Aaron Taylor, Monika J. Sun, Jay Wunder, Irene Andrulis, Nalan Gokgoz, Shintaro Iwata, Miki Ohira, Mark Krailo, Don Barkauskas, Lisa Teot, Timothy Triche, Silvia de Toledo, Antonio S. Petrilli, Jaime M. Guidry Auvil, Richard Gorlick, Malcolm A. Smith, Daniela Gerhard, Ching C. Lau
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-307.
https://doi.org/10.1158/1538-7445.AM2020-LB-307
Published: 15 August 2020
View article titled, Abstract LB-307: Translational and mechanistic implications of osteosarcoma genomics: A TARGET report
Journal Articles

Abstract 1315: Estimating sex-specific effects of genetic loci associated with glioma risk

Quinn T. Ostrom, Ben Kinnersley, Margaret Wrensch, Jeanette E. Eckel-Passow, Georgina Armstrong, Terri Rice, Yanwen Chen, John Wiencke, Lucie McCoy, Helen Hansen, Christopher Amos, Jonine L. Bernstein, Elizabeth B. Claus, Dora Il'yasova, Christoffer Johansen, Daniel Lachance, Rose Lai, Ching C. Lau, Ryan T. Merrell, Sara H. Olson, Siegal Sadetzki, Joellen Schildkraut, Sanjay Shete, Richard S. Houlston, Robert B. Jenkins, Beatrice Melin, Melissa Bondy, Jill S. Barnholtz-Sloan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1315.
https://doi.org/10.1158/1538-7445.AM2017-1315
Published: 01 July 2017
View article titled, Abstract 1315: Estimating sex-specific effects of genetic loci associated with glioma risk
Journal Articles

Abstract 3004: Comparison of somatic alterations in the genome and transcriptome of 1,705 pediatric leukemia and solid tumors: a report from the Children’s Oncology Group (COG) - NCI TARGET Project

Xiaotu Ma, Yu Liu, Yanling Liu, Michael Edmonson, Charles Gawad, Xin Zhou, Yongjin Li, Michael Rusch, John Easton, Mark Wilkinson, Leandro C. Hermida, Sean Davis, Malcolm Smith, Jaime Guidry Auvil, Paul Meltzer, Ching C. Lau, Elizabeth Perlman, John M. Maris, Soheil Meshinchi, Stephen P. Hunger, Daniela S. Gerhard, Jinghui Zhang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3004.
https://doi.org/10.1158/1538-7445.AM2017-3004
Published: 01 July 2017
View article titled, Abstract 3004: Comparison of somatic alterations in the genome and transcriptome of 1,705 pediatric leukemia and solid tumors: a report from the Children’s Oncology Group (COG) - NCI TARGET Project
Journal Articles

Abstract 3214: Systematic drug repurposing for faster cures of pediatric cancer identifies that Digoxin prolongs survival in a PDOX model of group 4 medulloblastoma

Lei Huang, Sarah G. Injac, Hong Zhao, Qi Lin, Mari Kogiso, Chris T. Man, Xiao-Nan Li, Ching C. Lau, Stephen T. Wong
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3214.
https://doi.org/10.1158/1538-7445.AM2017-3214
Published: 01 July 2017
View article titled, Abstract 3214: Systematic drug repurposing for faster cures of pediatric cancer identifies that Digoxin prolongs survival in a PDOX model of group 4 medulloblastoma
Journal Articles

Abstract 2445: Cytoplasmic mislocalization of p27 promotes metastasis and its autoantibody correlates with prognosis in osteosarcoma

Manjula Nakka, Yiting Li, Aaron J. Kelly, Ching C. Lau, Mark Krailo, Donald A. Barkauskas, John Hicks, Tsz-Kwong Man
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2445.
https://doi.org/10.1158/1538-7445.AM2016-2445
Published: 15 July 2016
View article titled, Abstract 2445: Cytoplasmic mislocalization of p27 promotes metastasis and its autoantibody correlates with prognosis in osteosarcoma
Journal Articles

Abstract 3446: Aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) and the risk of glioma: Results from the Glioma International Case Control Study

Rose K. Lai, Renke Zhou, E. Susan Amirian, Christoffer Johansen, Michael E. Scheurer, Georgina N. Armstrong, Ching C. Lau, Elizabeth B. Claus, Jill S. Barnholtz-Sloan, Dora Il’yasova, Joellen Schildkraut, Francis Ali-Osman, Siegal Sadetzki, Richard Houlston, Robert B. Jenkins, Daniel Lachance, Sara H. Olson, Jonine L. Bernstein, Ryan T. Merrell, Margaret R. Wrensch, Faith G. Davis, Sanjay Shete, Christopher I. Amos, Beatrice S. Melin, Melissa Bondy
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3446.
https://doi.org/10.1158/1538-7445.AM2016-3446
Published: 15 July 2016
View article titled, Abstract 3446: Aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) and the risk of glioma: Results from the Glioma International Case Control Study
Journal Articles

p27 Is a Candidate Prognostic Biomarker and Metastatic Promoter in Osteosarcoma

Yiting Li, Manjula Nakka, Aaron J. Kelly, Ching C. Lau, Mark Krailo, Donald A. Barkauskas, John M. Hicks, Tsz-Kwong Man
Journal: Cancer Research
Cancer Res (2016) 76 (13): 4002–4011.
https://doi.org/10.1158/0008-5472.CAN-15-3189
Published: 30 June 2016
View article titled, p27 Is a Candidate Prognostic Biomarker and Metastatic Promoter in Osteosarcoma
Open the PDF for p27 Is a Candidate Prognostic Biomarker and Metastatic Promoter in Osteosarcoma in another window
Includes: Supplementary data
Journal Articles

Abstract 5163: A high level of circulating CXCL10 at initial diagnosis is associated with poor prognosis of osteosarcoma patients

Ricardo J. Flores, Aaron J. Kelly, Yiting Li, Manjula Nakka, Ching C. Lau, John Hicks, Tsz-Kwong Man
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5163.
https://doi.org/10.1158/1538-7445.AM2015-5163
Published: 01 August 2015
View article titled, Abstract 5163: A high level of circulating CXCL10 at initial diagnosis is associated with poor prognosis of osteosarcoma patients
Journal Articles

Abstract 853: The role of germline microRNA-related polymorphisms on pediatric medulloblastoma prognosis and survival

Erin C. Peckham, Philip J. Lupo, Austin L. Brown, Mehmet Fatih Okcu, Ching C. Lau, Surya Rednam, Michael E. Scheurer
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 853.
https://doi.org/10.1158/1538-7445.AM2015-853
Published: 01 August 2015
View article titled, Abstract 853: The role of germline microRNA-related polymorphisms on pediatric medulloblastoma prognosis and survival
Journal Articles

Abstract 5576: MnSOD polymorphism is associated with ototoxicity in pediatric medulloblastoma patients

Austin L. Brown, Philip J. Lupo, Mehmet F. Okcu, Ching C. Lau, Surya P. Rednam, Michael E. Scheurer
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5576.
https://doi.org/10.1158/1538-7445.AM2015-5576
Published: 01 August 2015
View article titled, Abstract 5576: MnSOD polymorphism is associated with ototoxicity in pediatric medulloblastoma patients
Journal Articles

Abstract 1193: Establishment of patient tumor-derived orthotopic xenograft models of metastatic pediatric germinoma

Holly B. Lindsay, Mari Kogiso, Lin Qi, Teo Wan Yee, Yulun Huang, Hua Mao, Frank Lin, Patricia Baxter, Jack M. Su, Keita Terashima, Laszlo Perlaky, Ching C. Lau, Donald W. Parsons, Murali Chintagumpala, Xiao-Nan Li
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1193.
https://doi.org/10.1158/1538-7445.AM2014-1193
Published: 01 October 2014
View article titled, Abstract 1193: Establishment of patient tumor-derived orthotopic xenograft models of metastatic pediatric germinoma
Journal Articles

Abstract 1484: CD57 defines a novel maker of glioblastoma stem cells that have greater invasive potential than CD133+ tumor cells

Lin Qi, Yu-lun Huang, Mari Kogiso, Hua Mao, Patricia Baxter, Jack MF Su, Laszlo Perlaky, Ching C. Lau, Murali Chintagumpala, Xiao-Nan Li
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1484.
https://doi.org/10.1158/1538-7445.AM2014-1484
Published: 01 October 2014
View article titled, Abstract 1484: CD57 defines a novel maker of glioblastoma stem cells that have greater invasive potential than CD133+ tumor cells
Journal Articles

Abstract LB-355: Whole-exome sequencing of intracranial germ cell tumors reveals frequent mutations in KIT and RAS pathways and histone demethylases.

Linghua Wang, Shigeru Yamaguchi, Keita Terashima, Matthew D. Burstein, Jiayi M. Sun, Tomonari Suzuki, Ryo Nishikawa, Hideo Nakamura, Atsushi Natsume, Shunsuke Terasaka, Ho-Keung Ng, Robert C. Dauser, William E. Whitehead, Adesina M. Adekunle, Donna M. Muzny, Richard A. Gibbs, Ching C. Lau, David A. Wheeler
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-355.
https://doi.org/10.1158/1538-7445.AM2013-LB-355
Published: 15 April 2013
View article titled, Abstract LB-355: Whole-exome sequencing of intracranial germ cell tumors reveals frequent mutations in KIT and RAS pathways and histone demethylases.
Journal Articles

Abstract 1996: Identification of four subgroups of Triple Negative Breast Cancer (TNBC) by genomic profiling.

Matthew D. Burstein, Anna Tsimelzon, Kyle R. Covington, Suzanne AW Fuqua, Jenny C. Chang, Susan G. Hilsenbeck, C Kent Osborne, Gordon B. Mills, Ching C. Lau, Powel H. Brown
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1996.
https://doi.org/10.1158/1538-7445.AM2013-1996
Published: 15 April 2013
View article titled, Abstract 1996: Identification of four subgroups of Triple Negative Breast Cancer (TNBC) by genomic profiling.
Journal Articles

Abstract 3828: Identification of prognostic markers in osteosarcoma using a systems biology approach.

Ricardo J. Flores, Yiting Li, Alexander Yu, Serrine Lau, Marina Vannucci, Ching C. Lau, Tsz-Kwong Man
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3828.
https://doi.org/10.1158/1538-7445.AM2013-3828
Published: 15 April 2013
View article titled, Abstract 3828: Identification of prognostic markers in osteosarcoma using a systems biology approach.
Journal Articles

Abstract 3824: Integrated analysis of array-CGH and gene expression profiling identifies HSPA5 as a prognostic marker in SHH pathway-actived Medulloblastoma.

Angela Kwok-Fung Lo, Jian Wang, Jianhe Shen, Alexander Yu, Wing-Yuk Chow, Jack Su, Adekunle Adesina, Robert Dauser, William Whitehead, Murali Chintagumpala, Rudy Guerra, Tsz-Kwong Man, Ching C. Lau
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3824.
https://doi.org/10.1158/1538-7445.AM2013-3824
Published: 15 April 2013
View article titled, Abstract 3824: Integrated analysis of array-CGH and gene expression profiling identifies HSPA5 as a prognostic marker in SHH pathway-actived Medulloblastoma.
Journal Articles

Abstract 2364: Identification of therapy resistant pediatric brain tumor cells that have extraordinary survival and tumorigenic capabilities: The ultimate seed cells that drives the growth of autopsied tumor cells in mouse brains

Patricia A. Baxter, Zhigang Liu, Xuimei Zhao, Hua Mao, Yulung Huang, Yujing Zhang, Jack M. Su, Adekunle M. Adesina, Murali Chintagumpala, Ching C. Lau, Susan M. Blaney, Xiao-nan Li
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2364.
https://doi.org/10.1158/1538-7445.AM2012-2364
Published: 15 April 2012
View article titled, Abstract 2364: Identification of therapy resistant pediatric brain tumor cells that have extraordinary survival and tumorigenic capabilities: The ultimate seed cells that drives the growth of autopsied tumor cells in mouse brains
Journal Articles

Abstract 3400: A systems biology approach reveals common metastatic pathways in osteosarcoma

Ricardo J. Flores, Yiting Li, Marina Vanucci, Ching C. Lau, Tsz-Kwong Man, Serrine S. Lau
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3400.
https://doi.org/10.1158/1538-7445.AM2012-3400
Published: 15 April 2012
View article titled, Abstract 3400: A systems biology approach reveals common metastatic pathways in osteosarcoma
Journal Articles

Abstract 5305: Phosphorylations of Serine-10 and Tyrosine-198 residues in the cytoplasmic mislocalized p27 are critical to migration and invasion of osteosarcoma cells

Yiting Li, Ricardo J. Flores, John Hicks, Murali Chintagumpala, Ching C. Lau, Tsz Kwong Man
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5305.
https://doi.org/10.1158/1538-7445.AM2012-5305
Published: 15 April 2012
View article titled, Abstract 5305: Phosphorylations of Serine-10 and Tyrosine-198 residues in the cytoplasmic mislocalized p27 are critical to migration and invasion of osteosarcoma cells