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Journal Articles

Abstract LB351: AXIN2 promotes WNT-target gene expression via cross-feedback between WNT and retinoic acid signaling pathways based on transcriptionally co-regulated components

Chi Zhang, Gilberto Schleiniger, Caroline Facey, Lynn Opdenaker, Bruce Boman

Cancer Res (2025) 85 (8_Supplement_2): LB351.

https://doi.org/10.1158/1538-7445.AM2025-LB351

Published: 25 April 2025

View articletitled, Abstract LB351: AXIN2 promotes WNT-target gene expression via cross-feedback between WNT and retinoic acid signaling pathways based on transcriptionally co-regulated components

Journal Articles

Abstract LB452: The role of dysregulated retinoid receptors in colorectal cancer

Bruce M. Boman, Brooke Coulbourne, Anh Nguyen, Caroline Facey, Chi Zhang

Cancer Res (2025) 85 (8_Supplement_2): LB452.

https://doi.org/10.1158/1538-7445.AM2025-LB452

Published: 25 April 2025

View articletitled, Abstract LB452: The role of dysregulated retinoid receptors in colorectal cancer

Journal Articles

Abstract CT170: ALTAS: A phase II trial of anlotinib in combination with TAS-102 in patients with metastatic colorectal cancers

Qing Liu, Chi Zhang, Xiaojing Xu, Yiyi Yu, Tianshu Liu

Cancer Res (2025) 85 (8_Supplement_2): CT170.

https://doi.org/10.1158/1538-7445.AM2025-CT170

Published: 25 April 2025

View articletitled, Abstract CT170: ALTAS: A phase II trial of anlotinib in combination with TAS-102 in patients with metastatic colorectal cancers

Journal Articles

Abstract 1353: Characterizing biological functional changes in cancer tumor microenvironment by integrating histology-based gene imputation with scRNA-seq foundation models

Paveethran Swaminathan, Pengtao Dang, Haiqi Zhu, Zheng An, Xin Lu, Zhi Li, Yue Fang, Min Yang, Yuhui Wei, Tingbo Guo, Xinyu Zhou, Xiao Wang, Jia Wang, Chi Zhang, Sha Cao

Cancer Res (2025) 85 (8_Supplement_1): 1353.

https://doi.org/10.1158/1538-7445.AM2025-1353

Published: 21 April 2025

View articletitled, Abstract 1353: Characterizing biological functional changes in cancer tumor microenvironment by integrating histology-based gene imputation with scRNA-seq foundation models

Journal Articles

Abstract 5376: Unraveling the metabolic Achilles' heel of pancreatic ductal adenocarcinoma: targeting ref-1 and beyond

Silpa Gampala, Jacqueline Peil, Sanya Hayati, Sonia Kiran, Caleb Cheng, Elizabeth A. Potchanant, Costas Lyssiotis, Chi Zhang, Sha Cao, Mark R. Kelley, Melissa L. Fishel

Cancer Res (2025) 85 (8_Supplement_1): 5376.

https://doi.org/10.1158/1538-7445.AM2025-5376

Published: 21 April 2025

View articletitled, Abstract 5376: Unraveling the metabolic Achilles' heel of pancreatic ductal adenocarcinoma: targeting ref-1 and beyond

Journal Articles

Abstract 2908: WEE1 as a therapeutic target in TP53 and ARID1A concurrent mutant colorectal cancers

Chi Zhang, Ke Peng, Qing Liu, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Qihong Huang, Tianshu Liu

Cancer Res (2025) 85 (8_Supplement_1): 2908.

https://doi.org/10.1158/1538-7445.AM2025-2908

Published: 21 April 2025

View articletitled, Abstract 2908: WEE1 as a therapeutic target in TP53 and ARID1A concurrent mutant colorectal cancers

Journal Articles

Abstract 7032: The role of general control nonderepressible 2 (GCN2) kinase in leukemogenesis and therapeutic response to L-asparaginase

Rodney Claude, Sankalp Srivastava, Minghua Zhong, Can Chen, Sandeep Batra, Utpal Dave, Chi Zhang, Yue Fang, Kirk Staschke, Ronald A. Wek, Ji Zhang

Cancer Res (2025) 85 (8_Supplement_1): 7032.

https://doi.org/10.1158/1538-7445.AM2025-7032

Published: 21 April 2025

View articletitled, Abstract 7032: The role of general control nonderepressible 2 (GCN2) kinase in leukemogenesis and therapeutic response to L-asparaginase

Journal Articles

Abstract 1412: Translational regulation of MYC in acute lymphoblastic leukemia

Sankalp Srivastava, Jagannath Misra, Rodney Claude, Michael Holmes, Gang Peng, Kirk Staschke, Sandeep Batra, Utpal Dave, Chi Zhang, Ronald Wek, Jing Fan, Ji Zhang

Cancer Res (2025) 85 (8_Supplement_1): 1412.

https://doi.org/10.1158/1538-7445.AM2025-1412

Published: 21 April 2025

View articletitled, Abstract 1412: Translational regulation of MYC in acute lymphoblastic leukemia

Journal Articles

Abstract C049: Computational Methods for Central and Lipid Metabolism Networks Analysis to Reveals Flux Change in PDAC

Sha Cao, Haiqi Zhu, Yijie Wang, Melissa Fishel, Chi Zhang

Cancer Res (2024) 84 (17_Supplement_2): C049.

https://doi.org/10.1158/1538-7445.PANCREATIC24-C049

Published: 15 September 2024

View articletitled, Abstract C049: Computational Methods for Central and Lipid Metabolism Networks Analysis to Reveals Flux Change in PDAC

Journal Articles

Abstract B072: Pharmacological depletion of fibrinogen suppresses the growth of primary tumors and liver metastasis of pancreatic cancer

Nayela N Chowdhury, Dana K Mitchell, Kadri Kangro, Kierra Eldridge, Sara Abrahams, Francesca Ferraresso, Lih J Juang, Silpa Gampala, Kylee Brewster, Alexey Revenko, Christian Kastrup, Paul R Territo, D Wade Clapp, Jorge A Belgodere, Bumsoo Han, Alisa S Wolberg, Chi Zhang, Matthew J Flick, Melissa L Fishel

Cancer Res (2024) 84 (17_Supplement_2): B072.

https://doi.org/10.1158/1538-7445.PANCREATIC24-B072

Published: 15 September 2024

View articletitled, Abstract B072: Pharmacological depletion of fibrinogen suppresses the growth of primary tumors and liver metastasis of pancreatic cancer

Journal Articles

Abstract 5599: Role of HOX gene expression in differentiation of colon cancer stem cells

Brian T. Osmond, Caroline O. Facey, Lynn O. Opdenaker, Chi Zhang, Bruce M. Boman

Cancer Res (2024) 84 (6_Supplement): 5599.

https://doi.org/10.1158/1538-7445.AM2024-5599

Published: 22 March 2024

View articletitled, Abstract 5599: Role of HOX gene expression in differentiation of colon cancer stem cells

Journal Articles

Abstract 1350: KD6001: A promising new anti-CTLA-4 human monoclonal antibody for cancer therapy

Yi Chen, Peng Li, Guobo Fang, Heng Wu, Chi Zhang, Zeling Cai

Cancer Res (2024) 84 (6_Supplement): 1350.

https://doi.org/10.1158/1538-7445.AM2024-1350

Published: 22 March 2024

View articletitled, Abstract 1350: KD6001: A promising new anti-CTLA-4 human monoclonal antibody for cancer therapy

Journal Articles

Abstract 1644: Exploring the role of a TERT intronic tandem repeat in regulating cell proliferative responses to environmental factors and cancer risk

Michelle Ho, Oscar Florez-Vargas, Maxwell Hogshead, Brenen Papenberg, Chia Han Lee, Chi Zhang, Kaitlin Forsythe, Wusheng Yan, Raj Chari, Ludmila Prokunina-Olsson

Cancer Res (2024) 84 (6_Supplement): 1644.

https://doi.org/10.1158/1538-7445.AM2024-1644

Published: 22 March 2024

View articletitled, Abstract 1644: Exploring the role of a TERT intronic tandem repeat in regulating cell proliferative responses to environmental factors and cancer risk

Journal Articles

Abstract 7082: Epidemiology meets epitranscriptomics: Exploring the cancer-related role of a novel TERT-antisense transcript and its regulation by RNA methylation

Brenen W. Papenberg, Oscar Florez-Vargas, Michelle Ho, Kaitlin Forsythe, Chi Zhang, Chia-Han Lee, Sam Mbulaiteye, Pedro J. Batista, Ludmila Prokunina-Olsson

Cancer Res (2024) 84 (6_Supplement): 7082.

https://doi.org/10.1158/1538-7445.AM2024-7082

Published: 22 March 2024

View articletitled, Abstract 7082: Epidemiology meets epitranscriptomics: Exploring the cancer-related role of a novel TERT-antisense transcript and its regulation by RNA methylation

Journal Articles

Abstract 6741: Targeting glutamine metabolism potentiates antigen presentation in colorectal cancer

Tao Yu, Kevin Van der Jeught, Haiqi Zhu, Zhuolong Zhou, Samantha Sharma, Sheng Liu, Ka Man So, Haniyeh Eyvani, Xiyu Wang, George E. Sandusky, Yunlong Liu, Mateusz Opyrchal, Sha Cao, Jun Wan, Chi Zhang, Xinna Zhang

Cancer Res (2024) 84 (6_Supplement): 6741.

https://doi.org/10.1158/1538-7445.AM2024-6741

Published: 22 March 2024

View articletitled, Abstract 6741: Targeting glutamine metabolism potentiates antigen presentation in colorectal cancer

Journal Articles

Abstract 5430: Discovery of CYP26A1 as a link between WNT and retinoic acid signaling pathways that modulates retinoid-induced differentiation of APC-mutant colorectal cancer cells

Caroline O. Facey, Victoria O. Hunsu, Chi Zhang, Brian T. Osmond, Lynn M. Opdenaker, Bruce M. Boman

Cancer Res (2024) 84 (6_Supplement): 5430.

https://doi.org/10.1158/1538-7445.AM2024-5430

Published: 22 March 2024

View articletitled, Abstract 5430: Discovery of CYP26A1 as a link between WNT and retinoic acid signaling pathways that modulates retinoid-induced differentiation of APC-mutant colorectal cancer cells

Journal Articles

Abstract 5452: AXIN2 differentially modulates stem cell subpopulations providing a potential therapeutic opportunity for targeting colorectal cancer stem cells

Chi Zhang, Caroline O. Facey, Lynn M. Opdenaker, Bruce M. Boman

Cancer Res (2024) 84 (6_Supplement): 5452.

https://doi.org/10.1158/1538-7445.AM2024-5452

Published: 22 March 2024

View articletitled, Abstract 5452: AXIN2 differentially modulates stem cell subpopulations providing a potential therapeutic opportunity for targeting colorectal cancer stem cells

Journal Articles

Abstract 1913: KD5005: HER-2 dependent strong potent anti-tumor activity of an anti-HER-2 mAb-TNFaimmunocytokine

YI CHEN, PENG LI, GUOBO FANG, HENG WU, CHI ZHANG, ZELING CAI

Cancer Res (2024) 84 (6_Supplement): 1913.

https://doi.org/10.1158/1538-7445.AM2024-1913

Published: 22 March 2024

View articletitled, Abstract 1913: KD5005: HER-2 dependent strong potent anti-tumor activity of an anti-HER-2 mAb-TNFaimmunocytokine

Journal Articles

Abstract 2434: Regulation of initiation and establishment of ovarian cancer metastasis by metastasis initiating cells

Ji Wang, Subramanyam Dasari, Chi Zhang, Anirban Kumar Mitra

Cancer Res (2023) 83 (7_Supplement): 2434.

https://doi.org/10.1158/1538-7445.AM2023-2434

Published: 04 April 2023

View articletitled, Abstract 2434: Regulation of initiation and establishment of ovarian cancer metastasis by metastasis initiating cells

Journal Articles

Abstract 2446: An investigation of HOX-regulatory mechanisms and their role in the SC origin of human CRC

Brian Osmond, Caroline O. Facey, Lynn M. Opdenaker, Chi Zhang, Bruce M. Boman

Cancer Res (2023) 83 (7_Supplement): 2446.

https://doi.org/10.1158/1538-7445.AM2023-2446

Published: 04 April 2023

View articletitled, Abstract 2446: An investigation of HOX-regulatory mechanisms and their role in the SC origin of human CRC

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Abstract LB351: AXIN2 promotes WNT-target gene expression via cross-feedback between WNT and retinoic acid signaling pathways based on transcriptionally co-regulated components

Abstract LB452: The role of dysregulated retinoid receptors in colorectal cancer

Abstract CT170: ALTAS: A phase II trial of anlotinib in combination with TAS-102 in patients with metastatic colorectal cancers

Abstract 1353: Characterizing biological functional changes in cancer tumor microenvironment by integrating histology-based gene imputation with scRNA-seq foundation models

Abstract 5376: Unraveling the metabolic Achilles' heel of pancreatic ductal adenocarcinoma: targeting ref-1 and beyond

Abstract 2908: WEE1 as a therapeutic target in TP53 and ARID1A concurrent mutant colorectal cancers

Abstract 7032: The role of general control nonderepressible 2 (GCN2) kinase in leukemogenesis and therapeutic response to L-asparaginase

Abstract 1412: Translational regulation of MYC in acute lymphoblastic leukemia

Abstract C049: Computational Methods for Central and Lipid Metabolism Networks Analysis to Reveals Flux Change in PDAC

Abstract B072: Pharmacological depletion of fibrinogen suppresses the growth of primary tumors and liver metastasis of pancreatic cancer

Abstract 5599: Role of HOX gene expression in differentiation of colon cancer stem cells

Abstract 1350: KD6001: A promising new anti-CTLA-4 human monoclonal antibody for cancer therapy

Abstract 1644: Exploring the role of a TERT intronic tandem repeat in regulating cell proliferative responses to environmental factors and cancer risk

Abstract 7082: Epidemiology meets epitranscriptomics: Exploring the cancer-related role of a novel TERT-antisense transcript and its regulation by RNA methylation

Abstract 6741: Targeting glutamine metabolism potentiates antigen presentation in colorectal cancer

Abstract 5430: Discovery of CYP26A1 as a link between WNT and retinoic acid signaling pathways that modulates retinoid-induced differentiation of APC-mutant colorectal cancer cells

Abstract 5452: AXIN2 differentially modulates stem cell subpopulations providing a potential therapeutic opportunity for targeting colorectal cancer stem cells

Abstract 1913: KD5005: HER-2 dependent strong potent anti-tumor activity of an anti-HER-2 mAb-TNFaimmunocytokine

Abstract 2434: Regulation of initiation and establishment of ovarian cancer metastasis by metastasis initiating cells

Abstract 2446: An investigation of HOX-regulatory mechanisms and their role in the SC origin of human CRC

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