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Chi V. Dang
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Journal Articles

Abstract B085: The HIF-2 transcription factor mediates resistance to ferroptosis in pancreatic adenocarcinoma

Maimon E Hubbi, Catherine Wang, Erin Hollander, Yasir Suhail, Kshitiz, Alexander Muir, Ben Z Stanger, Chi V Dang
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): B085.
https://doi.org/10.1158/1538-7445.PANCREATIC24-B085
Published: 15 September 2024
View article titled, Abstract B085: The HIF-2 transcription factor mediates resistance to ferroptosis in pancreatic adenocarcinoma
Journal Articles

Abstract B064: Uncovering the lineage state specific regulation of STING in neuroblastoma

Matthew Shapiro, Pamela Mishra, Alaa Narch, Jessica Dessau, Chi V. Dang, Adam Wolpaw
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): B064.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-B064
Published: 05 September 2024
View article titled, Abstract B064: Uncovering the lineage state specific regulation of STING in neuroblastoma
Journal Articles

Clocking Cancer Immunotherapy Responses

Catherine L. Wang, Xue Zhang, Chi V. Dang
Journal: Cancer Research
Cancer Res (2024) 84 (17): 2756–2758.
https://doi.org/10.1158/0008-5472.CAN-24-2083
Published: 04 September 2024
View article titled, Clocking Cancer Immunotherapy Responses
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Journal Articles

The Warburg Effect Revisited through Blood and Electron Flow

Yahui Wang, Chi V. Dang
Journal: Cancer Research
Cancer Res (2024) 84 (13): 2046–2048.
https://doi.org/10.1158/0008-5472.CAN-24-0474
Published: 02 July 2024
View article titled, The Warburg Effect Revisited through Blood and Electron Flow
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Journal Articles

Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer

Yogev Sela, Jinyang Li, Shivahamy Maheswaran, Robert Norgard, Salina Yuan, Maimon Hubbi, Miriam Doepner, Jimmy P. Xu, Elaine S. Ho, Clementina Mesaros, Colin Sheehan, Grace Croley, Alexander Muir, Ian A. Blair, Ophir Shalem, Chi V. Dang, Ben Z. Stanger
Journal: Cancer Research
Cancer Res (2022) 82 (10): 1890–1908.
https://doi.org/10.1158/0008-5472.CAN-22-0431
Published: 16 May 2022
View article titled, Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer
Open the PDF for Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer in another window
Includes: Multimedia, Supplementary data
Journal Articles

Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers

Adam J. Wolpaw, Richard Bayliss, Gabriele Büchel, Chi V. Dang, Martin Eilers, W. Clay Gustafson, Gwenn H. Hansen, Natalia Jura, Stefan Knapp, Mark A. Lemmon, David Levens, John M. Maris, Ronen Marmorstein, Steven J. Metallo, Julie R. Park, Linda Z. Penn, Michael Rape, Martine F. Roussel, Kevan M. Shokat, William P. Tansey, Kliment A. Verba, Seychelle M. Vos, William A. Weiss, Elmar Wolf, Yaël P. Mossé
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (7): 1627–1632.
https://doi.org/10.1158/0008-5472.CAN-20-3108
Published: 01 April 2021
View article titled, Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers
Open the PDF for Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers in another window
Journal Articles

Abstract IA22: Tracking metabolic compartmentation and epigenetic metabolism in human lung cancer

Teresa W-M Fan, Andrew N. Lane, Jason A. Brandon, Joonseon Yang, Chi V. Dang, Richard M. Higashi
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): IA22.
https://doi.org/10.1158/1538-7445.EPIMETAB20-IA22
Published: 02 December 2020
View article titled, Abstract IA22: Tracking metabolic compartmentation and epigenetic metabolism in human lung cancer
Journal Articles

Abstract 4359: Oscillatory HIF-1α induction promotes proliferation of hypoxic cells through a lactate dependent quorum autophagy response

Kshitiz ., Junaid Afzal, Yasir Suhail, Hao Chang, Chi V. Dang, Andre Levchenko
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4359.
https://doi.org/10.1158/1538-7445.AM2019-4359
Published: 01 July 2019
View article titled, Abstract 4359: Oscillatory HIF-1α induction promotes proliferation of hypoxic cells through a lactate dependent quorum autophagy response
Journal Articles

MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels

Yunqi Lu, Zhongyi Hu, Lingegowda S. Mangala, Zachary E. Stine, Xiaowen Hu, Dahai Jiang, Yan Xiang, Youyou Zhang, Sunila Pradeep, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Angelo M. DeMarzo, Anil K. Sood, Lin Zhang, Chi V. Dang
Journal: Cancer Research
Cancer Res (2018) 78 (1): 64–74.
https://doi.org/10.1158/0008-5472.CAN-17-0815
Published: 02 January 2018
View article titled, MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels
Open the PDF for MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels in another window
Includes: Supplementary data
Journal Articles

Abstract 2669: Glutaminase alternative splicing controls tumor growth and metabolism

Zachary Stine, Zandra E. Walton, Lin Zhang, Teresa MW Fan, Andrew N. Lane, Chi V. Dang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2669.
https://doi.org/10.1158/1538-7445.AM2016-2669
Published: 15 July 2016
View article titled, Abstract 2669: Glutaminase alternative splicing controls tumor growth and metabolism
Journal Articles

Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function

N.V. Rajeshkumar, Prasanta Dutta, Shinichi Yabuuchi, Roeland F. de Wilde, Gary V. Martinez, Anne Le, Jurre J. Kamphorst, Joshua D. Rabinowitz, Sanjay K. Jain, Manuel Hidalgo, Chi V. Dang, Robert J. Gillies, Anirban Maitra
Journal: Cancer Research
Cancer Res (2015) 75 (16): 3355–3364.
https://doi.org/10.1158/0008-5472.CAN-15-0108
Published: 13 August 2015
View article titled, Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function
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Includes: Supplementary data
Journal Articles

Abstract 4708: Mammalian glutamine metabolism controls circadian rhythm through regulation of reactive oxygen species

Brian J. Altman, Zachary E. Stine, Annie L. Hsieh, Ralph J. Deberardinis, Chi V. Dang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4708.
https://doi.org/10.1158/1538-7445.AM2015-4708
Published: 01 August 2015
View article titled, Abstract 4708: Mammalian glutamine metabolism controls circadian rhythm through regulation of reactive oxygen species
Journal Articles

Abstract 2957: Inhibition of glutaminase induces slows tumor growth cell autonomously and promotes survival in a MYC driven hepatocellular carcinoma mouse model

Zachary Stine, Yan Xiang, Jinsong Xia, Ping Gao, Ramani Dinavahi, Chi V. Dang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2957.
https://doi.org/10.1158/1538-7445.AM2014-2957
Published: 01 October 2014
View article titled, Abstract 2957: Inhibition of glutaminase induces slows tumor growth cell autonomously and promotes survival in a MYC driven hepatocellular carcinoma mouse model
Journal Articles

Abstract 2953: Rev-erbα modulates Myc-driven cancer cell growth and altered metabolism

Brian J. Altman, Annie Hsieh, Arvin M. Gouw, Zachary E. Stine, Anand Venkataraman, David I. Bellovin, Sharon J. Diskin, Wenyun Lu, Sisi Zhang, Dean W. Felsher, John M. Maris, Mitchell A. Lazar, Joshua D. Rabinowitz, John B. Hogenesch, Chi V. Dang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2953.
https://doi.org/10.1158/1538-7445.AM2014-2953
Published: 01 October 2014
View article titled, Abstract 2953: Rev-erbα modulates Myc-driven cancer cell growth and altered metabolism
Journal Articles

Abstract 1419: Oncogenic Myc disrupts NAMPT circadian oscillation in mouse hepatocellular carcinoma cell line

Annie L. Hsieh, Brian J. Altman, Anand Venkataraman, David I. Bellovin, Dean W. Felsher, John B. Hogenesch, Chi V. Dang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1419.
https://doi.org/10.1158/1538-7445.AM2014-1419
Published: 01 October 2014
View article titled, Abstract 1419: Oncogenic Myc disrupts NAMPT circadian oscillation in mouse hepatocellular carcinoma cell line
Journal Articles

Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis

Joanne R. Doherty, Chunying Yang, Kristen E.N. Scott, Michael D. Cameron, Mohammad Fallahi, Weimin Li, Mark A. Hall, Antonio L. Amelio, Jitendra K. Mishra, Fangzheng Li, Mariola Tortosa, Heide Marika Genau, Robert J. Rounbehler, Yunqi Lu, Chi V. Dang, K. Ganesh Kumar, Andrew A. Butler, Thomas D. Bannister, Andrea T. Hooper, Keziban Unsal-Kacmaz, William R. Roush, John L. Cleveland
Journal: Cancer Research
Cancer Res (2014) 74 (3): 908–920.
https://doi.org/10.1158/0008-5472.CAN-13-2034
Published: 02 February 2014
View article titled, Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
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Includes: Supplementary data
Journal Articles

Evaluation of LDH-A and Glutaminase Inhibition In Vivo by Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopy of Tumors

Prasanta Dutta, Anne Le, David L. Vander Jagt, Takashi Tsukamoto, Gary V. Martinez, Chi V. Dang, Robert J. Gillies
Journal: Cancer Research
Cancer Res (2013) 73 (14): 4190–4195.
https://doi.org/10.1158/0008-5472.CAN-13-0465
Published: 15 July 2013
View article titled, Evaluation of LDH-A and Glutaminase Inhibition <em>In Vivo</em> by Hyperpolarized <sup>13</sup>C-Pyruvate Magnetic Resonance Spectroscopy of Tumors
Open the PDF for Evaluation of LDH-A and Glutaminase Inhibition <em>In Vivo</em> by Hyperpolarized <sup>13</sup>C-Pyruvate Magnetic Resonance Spectroscopy of Tumors in another window
Journal Articles

Abstract 4616: Oncogenic c- and N-Myc disrupt circadian rhythm.

Brian J. Altman, Annie Hsieh, Arvin Gouw, Anand Venkataraman, Bo Li, David Bellovin, M. Celeste Simon, Dean Felsher, John Hogenesch, Chi V. Dang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4616.
https://doi.org/10.1158/1538-7445.AM2013-4616
Published: 15 April 2013
View article titled, Abstract 4616: Oncogenic c- and N-Myc disrupt circadian rhythm.
Journal Articles

Abstract 5396: Targeting multiple components of the mammalian target of rapamycin (mTOR) signaling: A novel combination therapy to improve pancreatic cancer treatment.

N.V Rajeshkumar, Shinichi Yabuuchi, Chirag Patel, Shweta G. Pai, Dung T. Le, Daniel D. Von Hoff, Chi V. Dang, Anirban Maitra, Jonathan Powell
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5396.
https://doi.org/10.1158/1538-7445.AM2013-5396
Published: 15 April 2013
View article titled, Abstract 5396: Targeting multiple components of the mammalian target of rapamycin (mTOR) signaling: A novel combination therapy to improve pancreatic cancer treatment.
Journal Articles

Abstract 5242: Pancreatic cancer cell type specific oxygen dependent growth and drug sensitivity

Arvin M. Gouw, Annie L. Hsieh, Anne Le, Anirban Maitra, Chi V. Dang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5242.
https://doi.org/10.1158/1538-7445.AM2012-5242
Published: 15 April 2012
View article titled, Abstract 5242: Pancreatic cancer cell type specific oxygen dependent growth and drug sensitivity