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Journal Articles

Abstract 4779: Preclinical studies of BB-1705: An EGFR-targeting eribulin-containing ADC with an affinity optimized antibody to minimize potential toxicities to normal tissues

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Bing Xia, Lixia Cao, Jianfeng Yang, Cui Feng, Fangdun Jiang, Chen Li, Lixia Gu, Yifan Yang, Jing Tian, Jiasheng Geng, Likun Gong, Tingting Liu, Qiuping Qin, Ziping Wei, Yuhong Zhou
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4779.
https://doi.org/10.1158/1538-7445.AM2025-4779
Published: 21 April 2025
View articletitled, Abstract 4779: Preclinical studies of BB-1705: An EGFR-targeting eribulin-containing ADC with an affinity optimized antibody to minimize potential toxicities to normal tissues
Journal Articles

Abstract 2438: Bridging whole slide images and large language model for slide-level question answering

Free
Zeyu Gao, Kai He, Weiheng Su, William McGough, Ines Prata Machado, Mercedes Jimenez-Linan, Brian Rous, Rebecca Wray, Chengzu Li, Xiaobo Pang, Tieliang Gong, Mengling Feng, Chen Li, Mireia Crispin-Ortuzar
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2438.
https://doi.org/10.1158/1538-7445.AM2025-2438
Published: 21 April 2025
View articletitled, Abstract 2438: Bridging whole slide images and large language model for slide-level question answering
Journal Articles

Abstract 6173: Preclinical studies of BB-1712: A B7H3-targeting eribulin-containing ADC with the potential to overcome resistance to DNA topoisomerase I inhibitor-containing ADCs

Free
Yang Wang, Bing Xia, Lixia Cao, Jianfeng Yang, Cui Feng, Fangdun Jiang, Chen Li, Lixia Gu, Yifan Yang, Jing Tian, Jiasheng Geng, Qi Zhang, Ziping Wei, Yuhong Zhou
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6173.
https://doi.org/10.1158/1538-7445.AM2025-6173
Published: 21 April 2025
View articletitled, Abstract 6173: Preclinical studies of BB-1712: A B7H3-targeting eribulin-containing ADC with the potential to overcome resistance to DNA topoisomerase I inhibitor-containing ADCs
Journal Articles

Abstract 2243: Preclinical studies of BB-1709, a CD73-targeting ADC potentially suppresses tumor growth through dual mechanisms

Free
Bing Xia, Lixia Cao, Jianfeng Yang, Cui Feng, Fangdun Jiang, Chen Li, Lixia Gu, Yifan Yang, Jing Tian, Jiasheng Geng, Ziping Wei, Yuhong Zhou
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2243.
https://doi.org/10.1158/1538-7445.AM2025-2243
Published: 21 April 2025
View articletitled, Abstract 2243: Preclinical studies of BB-1709, a CD73-targeting ADC potentially suppresses tumor growth through dual mechanisms
Journal Articles

Abstract 3417: Preclinical studies of BR-2302: A HER3xEGFR bi-specific Exd-containing ADC

Free
Yang Wang, Bing Xia, Lixia Cao, Jianfeng Yang, Cui Feng, Fangdun Jiang, Chen Li, Lixia Gu, Yifan Yang, Jing Tian, Jiasheng Geng, Qi Zhang, Ziping Wei, Yuhong Zhou
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3417.
https://doi.org/10.1158/1538-7445.AM2025-3417
Published: 21 April 2025
View articletitled, Abstract 3417: Preclinical studies of BR-2302: A HER3xEGFR bi-specific Exd-containing ADC
Journal Articles

Chronic Stress Stimulates Protumor Macrophage Polarization to Propel Lung Cancer Progression

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Cuilan Liu, Hengwei Du, Guoxing Yu, Jingjing Qi, Hongliang Dong, Ruiqi Hu, Fei Wang, Bingjie Cui, Weiwei Chen, Qian Zhang, Chen Li, Ran Gao, Clemens A. Schmitt, Jiong Deng, Yong Yu, Jing Du
Journal: Cancer Research
Cancer Res (2025)
https://doi.org/10.1158/0008-5472.CAN-24-3481
Published: 09 April 2025
View articletitled, Chronic Stress Stimulates Protumor Macrophage Polarization to Propel Lung Cancer Progression
Open the PDF for Chronic Stress Stimulates Protumor Macrophage Polarization to Propel Lung Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 3251: QTOLIMOD: A specific TLR9 agonist nanomedicine with high anti-solid tumor activity

Free
Fei Su, Jun Bai, Chen Li, Yujing Wu, Jing Li, Xiaobin Zhao, Yongsheng Yang, Robert J. Lee
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3251.
https://doi.org/10.1158/1538-7445.AM2024-3251
Published: 22 March 2024
View articletitled, Abstract 3251: QTOLIMOD: A specific TLR9 agonist nanomedicine with high anti-solid tumor activity
Journal Articles

Abstract 1887: Preclinical development of BB-1701, a HER2-tageting eribulin-containing ADC with potent bystander effect and ICD activity

Free
Yang Wang, Bing Xia, Lixia Cao, Jianfeng Yang, Cui Feng, Fangdun Jiang, Chen Li, Lixia Gu, Yifan Yang, Jing Tian, Cindy Cheng, Keiji Furuuchi, James Fulmer, Arielle Verdi, Katherine Rybinski, Allis Soto, Earl Albone, Toshimitsu Uenaka, Likun Gong, Tingting Liu, Qiuping Qin, Ziping Wei, Yuhong Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1887.
https://doi.org/10.1158/1538-7445.AM2023-1887
Published: 04 April 2023
View articletitled, Abstract 1887: Preclinical development of BB-1701, a HER2-tageting eribulin-containing ADC with potent bystander effect and ICD activity
Journal Articles

Abstract CT222: Pembrolizumab (pembro) for previously treated advanced hepatocellular carcinoma (aHCC): Meta-analysis of the phase 3 KEYNOTE-240 and KEYNOTE-394 studies

Free
Richard S. Finn, Kangsheng Gu, Xi Chen, Philippe Merle, Kyung-Hun Lee, Mohamed Bouattour, Peiguo Cao, Wei Wang, Ann-Lii Cheng, Liangjun Zhu, Ho Yeong Lim, Masatoshi Kudo, Yueyin Pan, Ting-Tsung Chang, Julien Edeline, Wei Li, Ping Yang, Chen Li, Jianfeng Li, Abby B. Siegel, Shukui Qin
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT222.
https://doi.org/10.1158/1538-7445.AM2022-CT222
Published: 15 June 2022
View articletitled, Abstract CT222: Pembrolizumab (pembro) for previously treated advanced hepatocellular carcinoma (aHCC): Meta-analysis of the phase 3 KEYNOTE-240 and KEYNOTE-394 studies
Journal Articles

Genome-Wide Association Analyses Identify CATSPERE as a Mediator of Colorectal Cancer Susceptibility and Progression

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Yixuan Meng, Mulong Du, Dongying Gu, Chen Li, Shuwei Li, Qiuyi Zhang, Shuai Ben, Qiuyuan Zhu, Junyi Xin, Zhengdong Zhang, Zhibin Hu, Hongbing Shen, Kewei Jiang, Meilin Wang
Journal: Cancer Research
Cancer Res (2022) 82 (6): 986–997.
https://doi.org/10.1158/0008-5472.CAN-21-2948
Published: 15 March 2022
View articletitled, Genome-Wide Association Analyses Identify CATSPERE as a Mediator of Colorectal Cancer Susceptibility and Progression
Open the PDF for Genome-Wide Association Analyses Identify CATSPERE as a Mediator of Colorectal Cancer Susceptibility and Progression in another window
Includes: Supplementary data
Journal Articles

Abstract P3-06-04: Notch3 inhibits epithelia-mesenchymal transition by trans-activating GSK3β in breast cancer

Free
Chen Wei-Ling, Yong-Qu Zhang, Wen-He Huang, Min Chen, Yao-Chen Li, Guo-Jun Zhang
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-06-04.
https://doi.org/10.1158/1538-7445.SABCS21-P3-06-04
Published: 15 February 2022
View articletitled, Abstract P3-06-04: Notch3 inhibits epithelia-mesenchymal transition by trans-activating GSK3β in breast cancer
Journal Articles

Abstract 1745: On demand cytokine, a novel cytokine prodrug, demonstrates robust single agent efficacy without systemic toxicity in syngeneic tumor models

Free
Emma J. Langley, Chen Li, Tani-Ann Lee, Brian Grot, Jessica Zaid, Johnavon Kim, Deepak Yadav, Phillip Kim
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1745.
https://doi.org/10.1158/1538-7445.AM2021-1745
Published: 01 July 2021
View articletitled, Abstract 1745: On demand cytokine, a novel cytokine prodrug, demonstrates robust single agent efficacy without systemic toxicity in syngeneic tumor models
Journal Articles

Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury

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Yi Hu, Chun Yang, Tania Amorim, Mohsin Maqbool, Jenny Lin, Chen Li, Chuanfeng Fang, Li Xue, Ariel Kwart, Hua Fang, Mei Yin, Allison J. Janocha, Daisuke Tsuchimoto, Yusaku Nakabeppu, Xiaofeng Jiang, Alex Mejia-Garcia, Faiz Anwer, Jack Khouri, Xin Qi, Qing Y. Zheng, Jennifer S. Yu, Shan Yan, Thomas LaFramboise, Kenneth C. Anderson, Leal C. Herlitz, Nikhil C. Munshi, Jianhong Lin, Jianjun Zhao
Journal: Cancer Research
Cancer Res (2021) 81 (3): 713–723.
https://doi.org/10.1158/0008-5472.CAN-20-1010
Published: 01 February 2021
View articletitled, Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury
Open the PDF for Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury in another window
Includes: Supplementary data
Journal Articles

Targeting of CD38 by the Tumor Suppressor miR-26a Serves as a Novel Potential Therapeutic Agent in Multiple Myeloma

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Yi Hu, Huimin Liu, Chuanfeng Fang, Chen Li, Fjorela Xhyliu, Hayley Dysert, Juraj Bodo, Gabriel Habermehl, Benjamin E. Russell, Wenjun Li, Marcia Chappell, Xiaofeng Jiang, Sarah L. Ondrejka, Eric D. Hsi, Jaroslaw P. Maciejewski, Qing Yi, Kenneth C. Anderson, Nikhil C. Munshi, Geyou Ao, Jason N. Valent, Jianhong Lin, Jianjun Zhao
Journal: Cancer Research
Cancer Res (2020) 80 (10): 2031–2044.
https://doi.org/10.1158/0008-5472.CAN-19-1077
Published: 15 May 2020
View articletitled, Targeting of CD38 by the Tumor Suppressor miR-26a Serves as a Novel Potential Therapeutic Agent in Multiple Myeloma
Open the PDF for Targeting of CD38 by the Tumor Suppressor miR-26a Serves as a Novel Potential Therapeutic Agent in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Abstract 1319: Edge-based integration of multi-omics data gives more accurate prognostic prediction in pancreatic cancer

Free
Yidi Sun, Chen Li, Rong Zeng
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1319.
https://doi.org/10.1158/1538-7445.AM2018-1319
Published: 01 July 2018
View articletitled, Abstract 1319: Edge-based integration of multi-omics data gives more accurate prognostic prediction in pancreatic cancer
Journal Articles

Abstract 2727: Clinical significance of PTEN in UTUC

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Liang-Chen Li, Cheng-Keng Chuang, Hung-Ying Chiang, Ying-Tzu Chen, Po-Hung Lin, Kai-Jie Yu, See-Tong Pang, Wen Hui Weng*
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2727.
https://doi.org/10.1158/1538-7445.AM2017-2727
Published: 01 July 2017
View articletitled, Abstract 2727: Clinical significance of PTEN in UTUC
Journal Articles

Abstract 824: A novel mechanism of areca nut-induced oral cancer is through the conversion of cancer stem cells to acquire malignant phenotypes

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Yi-Chen Li, Ann-Joy Cheng
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 824.
https://doi.org/10.1158/1538-7445.AM2015-824
Published: 01 August 2015
View articletitled, Abstract 824: A novel mechanism of areca nut-induced oral cancer is through the conversion of cancer stem cells to acquire malignant phenotypes
Journal Articles

Abstract 2543: A dual-fluorescent reporter system facilitates identification of thiol compounds that suppress oxidative frameshift mutations

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Christina L. Chang, I-Chen Li, Chien-Yuan Chiu, Jhih-Ying Chi, Siao-Ru Jian, Chang-Lin Wu
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2543.
https://doi.org/10.1158/1538-7445.AM2012-2543
Published: 15 April 2012
View articletitled, Abstract 2543: A dual-fluorescent reporter system facilitates identification of thiol compounds that suppress oxidative frameshift mutations
Journal Articles

Abstract 26: Gene expression profiling of oral cancer cells chronic exposed to areca nut extract

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Yi-Chen Li, Ann-Joy Cheng
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 26.
https://doi.org/10.1158/1538-7445.AM2011-26
Published: 15 April 2011
View articletitled, Abstract 26: Gene expression profiling of oral cancer cells chronic exposed to areca nut extract
Journal Articles

Abstract 2979: Combined cdk1 and PARP inhibition results in tumor regression in a KrasG12D p53L/L murine lung adenocarcinoma model

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Neil Johnson, Yu-Chen Li, Zandra Walton, Danan Li, Lisa Moreau, Scott J. Rodig, Alan D. D'Andrea, Huw Thomas, David R. Newell, Nicola J. Curtin, Kwok K. Wong, Geoffrey I. Shapiro
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2979.
https://doi.org/10.1158/1538-7445.AM2011-2979
Published: 15 April 2011
View articletitled, Abstract 2979: Combined cdk1 and PARP inhibition results in tumor regression in a KrasG12D p53L/L murine lung adenocarcinoma model