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Chelsea Mayoh
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Journal Articles

Abstract 3044: The unexplored immune landscape of high-risk pediatric cancers

Chelsea Mayoh, Rachael L. Terry, Marie Wong, Loretta M. Lau, Dong Anh Khuong-Quang, Marion K. Mateos, Vanessa Tyrrell, Michelle Haber, David S. Ziegler, Mark J. Cowley, Joseph A. Trapani, Paul J. Neeson, Paul G. Ekert
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3044.
DOI: https://doi.org/10.1158/1538-7445.AM2021-3044
Published: 01 July 2021
View article titled, Abstract 3044: The unexplored immune landscape of high-risk pediatric cancers
Journal Articles

Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

Florida Voli, Emanuele Valli, Luigi Lerra, Kathleen Kimpton, Federica Saletta, Federico M. Giorgi, Daniele Mercatelli, Jourdin R.C. Rouaen, Sylvie Shen, Jayne E. Murray, Aria Ahmed-Cox, Giuseppe Cirillo, Chelsea Mayoh, Paul A. Beavis, Michelle Haber, Joseph A. Trapani, Maria Kavallaris, Orazio Vittorio
Journal: Cancer Research
Cancer Res (2020) 80 (19): 4129–4144.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-0471
Published: 02 October 2020
View article titled, Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
Click here to open pdf in another window PDF for Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
Includes: Supplementary data
Journal Articles

Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC–Driven Cancer Progression

Jixuan Gao, MoonSun Jung, Chelsea Mayoh, Pooja Venkat, Katherine M. Hannan, Jamie I. Fletcher, Alvin Kamili, Andrew J. Gifford, Eric P. Kusnadi, Richard B. Pearson, Ross D. Hannan, Michelle Haber, Murray D. Norris, Klaartje Somers, Michelle J. Henderson
Journal: Cancer Research
Cancer Res (2020) 80 (17): 3706–3718.
DOI: https://doi.org/10.1158/0008-5472.CAN-19-3914
Published: 02 September 2020
View article titled, Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC–Driven Cancer Progression
Click here to open pdf in another window PDF for Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC–Driven Cancer Progression
Includes: Supplementary data
Journal Articles

Abstract IA13: Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies

Michelle Haber, Laura Gamble, Lin Xiao, Ruby Pandher, Klaartje Somers, Jayne Murray, Aaminah Khan, Denise Yu, Laura Franshaw, Mark R. Burns, Maria Tsoli, Anahid Ehteda, Anthony Cesare, Aisling O’Connor, Francis Mussai, Carmela de Santo, Paul Cheng, Lioubov Korotchkina, Katerina Gurova, Vanessa Tyrrell, Emily Mould, Loretta Lau, Dong Anh Khuong Quang, Chelsea Mayoh, Greg Arndt, Paulette Barahona, Tim Failes, Jamie Fletcher, Noemi Fuentes- Bolanos, Marie-Emilie Gauthier, Andrew Gifford, Dylan Grebert-Wade, Alvin Kamili, Amit Kumar, Sumanth Nagabushan, Tracey O’Brien, Patrick Strong, Alexandra Sherstyuk, David Thomas, Toby Trahair, Katherine Tucker, Meera Warby, Marie Wong, Jinhan Xie, Kathryn Evans, Richard Lock, Olga B. Chernova, Michelle Henderson, Andrei V Gudkov, Paul Ekert, Mark J. Cowley, Glenn M. Marshall, David S. Ziegler, Murray D. Norris
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): IA13.
DOI: https://doi.org/10.1158/1538-7445.PEDCA19-IA13
Published: 15 July 2020
View article titled, Abstract IA13: Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies
Journal Articles

Abstract A35: P-Glycoprotein is a resistance mechanism for conventional induction chemotherapy but not ALK inhibitors in high-risk neuroblastoma

Caroline Atkinson, Carole Tactacan, Alvin Kamili, Federica Saletta, Christine Gana, Georgina Eden, Chelsea Mayoh, Richard Lock, Murray Norris, Michelle Haber, Andrew Gifford, Toby Trahair, Jamie Fletcher
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A35.
DOI: https://doi.org/10.1158/1538-7445.PEDCA19-A35
Published: 15 July 2020
View article titled, Abstract A35: P-Glycoprotein is a resistance mechanism for conventional induction chemotherapy but not ALK inhibitors in high-risk neuroblastoma
Journal Articles

Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer

Paulette Barahona, Alexandra Sherstyuk, Mark Cowley, Paul Ekert, Judy Kirk, Dong-Anh Khuong-Quang, Amit Kumar, Loretta Lau, Chelsea Mayoh, Glenn Marshall, Emily Moud, Tracey O’Brien, Mark Pinese, David Thomas, Vanessa Tyrell, David Ziegler, Michelle Haber, Katherine Tucker, Noemi Auxiliadora Fuentes-Bolanos, Meera Warby
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A03.
DOI: https://doi.org/10.1158/1538-7445.PEDCA19-A03
Published: 15 July 2020
View article titled, Abstract A03: Prevalence and spectrum of germline mutations in children with high-risk cancer
Journal Articles

Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer

Paulette Barahona, Jamie Fletcher, Noemi Fuentes-Bolanos, Marie-Emilie Gauthier, Michelle Haber, Richard B. Lock, Glenn M. Marshall, Chelsea Mayoh, Emily Mould, Sumanth Nagabushan, Murray Norris, Tracey O’Brien, Alexandra Sherstyuk, David Thomas, Toby Trahair, Katherine Tucker, Meera Warby, Marie Wong, David S. Ziegler, Vanessa J. Tyrrell, Paul Ekert, Mark J. Cowley, Loretta Lau, Dong-Anh Khuong Quang, Zero Childhood Cancer Program National Consortium
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A52.
DOI: https://doi.org/10.1158/1538-7445.PEDCA19-A52
Published: 15 July 2020
View article titled, Abstract A52: Zero Childhood Cancer (ZERO): A comprehensive precision medicine platform for children with high-risk cancer
Journal Articles

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

Jessica Koach, Jessica K. Holien, Hassina Massudi, Daniel R. Carter, Olivia C. Ciampa, Mika Herath, Taylor Lim, Janith A. Seneviratne, Giorgio Milazzo, Jayne E. Murray, Joshua A. McCarroll, Bing Liu, Chelsea Mayoh, Bryce Keenan, Brendan W. Stevenson, Michael A. Gorman, Jessica L. Bell, Larissa Doughty, Stefan Hüttelmaier, Andre Oberthuer, Matthias Fischer, Andrew J. Gifford, Tao Liu, Xiaoling Zhang, Shizhen Zhu, W. Clay Gustafson, Michelle Haber, Murray D. Norris, Jamie I. Fletcher, Giovanni Perini, Michael W. Parker, Belamy B. Cheung, Glenn M. Marshall
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5652–5667.
DOI: https://doi.org/10.1158/0008-5472.CAN-19-1112
Published: 01 November 2019
View article titled, Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface
Click here to open pdf in another window PDF for Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface
Includes: Supplementary data
Journal Articles

Abstract 3435: Targeting AKT activity inhibits MYCN and sensitizes neuroblastoma to chemotherapeutic agents

Marion Le Grand, Kathleen Kimpton, Christine Gana, Emanuele Valli, Chelsea Mayoh, Maria Kavallaris
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3435.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3435
Published: 01 July 2019
View article titled, Abstract 3435: Targeting AKT activity inhibits MYCN and sensitizes neuroblastoma to chemotherapeutic agents
Journal Articles

Abstract 2884: Establishment of patient-derived xenograft models for high-risk neuroblastoma

Alvin Kamili, Andrew J. Gifford, Nancy Li, Chelsea Mayoh, Georgina L. Eden, Jinhan Xie, Robyn E. Lukeis, Murray D. Norris, Michelle Haber, Geoffrey McCowage, Toby N. Trahair, Jamie I. Fletcher
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2884.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2884
Published: 01 July 2019
View article titled, Abstract 2884: Establishment of patient-derived xenograft models for high-risk neuroblastoma
Journal Articles

Abstract 3111: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer

Emily V. Mould, Loretta Lau, Greg Arndt, Paulette Barahona, Mark J. Cowley, Paul Ekert, Tim Failes, Jamie Fletcher, Andrew Gifford, Dylan Grebert-Wade, Michelle Haber, Alvin Kamili, Amit Kumar, Richard B. Lock, Glenn M. Marshall, Chelsea Mayoh, Murray Norris, Tracey O'Brien, Dong Anh Khuong Quang, Patrick Strong, Alexandra Sherstyuk, Toby Trahair, Maria Tsoli, Katherine Tucker, Meera Warby, Marie Wong, Jinhan Xie, David S. Ziegler, Vanessa Tyrrell
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3111.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3111
Published: 01 July 2019
View article titled, Abstract 3111: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer
Journal Articles

Abstract 3659: Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma

Zsuzsanna Nagy, Maxwell Kanikevich, Jessica Koach, Chelsea Mayoh, Daniel Carter, Tao Liu, Yanhua Du, Cizhong Jiang, Michelle Haber, Murray Norris, Belamy Cheung, Glenn Marshall
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3659.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3659
Published: 01 July 2019
View article titled, Abstract 3659: Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma
Journal Articles

Abstract 4741: Re-evaluating the role of P-glycoprotein in the resistance of high-risk neuroblastoma to standard-of-care chemotherapies

Caroline Atkinson, Carole M. Tactacan, Alvin Kamili, Federica Saletta, Christine Gana, Georgina L. Eden, Chelsea Mayoh, Richard B. Lock, Murray D. Norris, Michelle Haber, Andrew J. Gifford, Toby N. Trahair, Jamie I. Fletcher
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4741.
DOI: https://doi.org/10.1158/1538-7445.AM2019-4741
Published: 01 July 2019
View article titled, Abstract 4741: Re-evaluating the role of P-glycoprotein in the resistance of high-risk neuroblastoma to standard-of-care chemotherapies
Journal Articles

Abstract LB-138: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer

Emily Mould, Loretta Lau, Greg Arndt, Paulette Barahona, Mark Cowley, Paul Ekert, Tim Failes, Jamie Fletcher, Andrew Gifford, Michelle Haber, Alvin Kamili, Amit Kumar, Richard Lock, Glenn Marshall, Chelsea Mayoh, Scott Mead, Murray Norris, Tracey O'Brien, Mark Pinese, Dong Anh Khuong Quang, Toby Trahair, Maria Tsoli, Katherine Tucker, Meera Warby, Marie Wong, Jinhan Xie, David Ziegler, Vanessa Tyrrell
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-138.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-138
Published: 01 July 2018
View article titled, Abstract LB-138: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer
Journal Articles

Abstract LB-137: Integrated genomics: drug screening and personalized xenograft development approach to identify precision treatments for aggressive pediatric brain tumors

Maria Tsoli, Carol Wadham, Mark Pinese, Tim Failes, Swapna Joshi, Emily Mould, Julia Yin, Velimir Gayevski, Amit Kumar, Warren Kaplan, Paul Ekert, Laura Franshaw, Andrew Gifford, Martin Weber, Michael Rodriguez, Chelsea Mayoh, Richard Cohn, Greg Arndt, Richard Lock, Vanessa Tyrrell, Murray Norris, Michelle Haber, Loretta Lau, Dong Anh Khuong Quang, Marie Wong, Toby Trahair, Glenn M. Marshall, Mark J. Cowley, David S. Ziegler
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-137.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-137
Published: 01 July 2018
View article titled, Abstract LB-137: Integrated genomics: drug screening and personalized xenograft development approach to identify precision treatments for aggressive pediatric brain tumors
Journal Articles

Network Modeling of microRNA–mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

Chi Yan Ooi, Daniel R. Carter, Bing Liu, Chelsea Mayoh, Anneleen Beckers, Amit Lalwani, Zsuzsanna Nagy, Sara De Brouwer, Bieke Decaesteker, Tzong-Tyng Hung, Murray D. Norris, Michelle Haber, Tao Liu, Katleen De Preter, Frank Speleman, Belamy B. Cheung, Glenn M. Marshall
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (12): 3122–3134.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-3034
Published: 14 June 2018
View article titled, Network Modeling of microRNA–mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN
Click here to open pdf in another window PDF for Network Modeling of microRNA–mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN
Includes: Supplementary data
Journal Articles

Abstract 1175: Inhibition of NAMPT as a novel therapeutic strategy for infant leukemia

Klaartje Somers, Shiloh Middlemiss, Asel Biktasova, Mawar Karsa, Leanna Cheung, Angelika Kosciolek, Kathryn Evans, Chelsea Mayoh, Ursula R. Kees, Lioubov Korotchkina, Olga B. Chernova, Richard B. Lock, Andrei V. Gudkov, Michelle Haber, Murray D. Norris, Michelle J. Henderson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1175.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1175
Published: 01 July 2017
View article titled, Abstract 1175: Inhibition of NAMPT as a novel therapeutic strategy for infant leukemia