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Chapla Agarwal
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Journal Articles

Abstract 7304: Modulation of cytokine and chemokine profiles in pancreatic tumors and plasma via stage-specific intervention with Momordica Charantia juice in the LSL-KrasG12D/+, p48Cre/+ mouse model

Lakshmi Sai Pratyusha Bugata, Robin Kumar, Md. Imtiazul Kabir, Rama Kant, Chapla Agarwal, Rajesh Agarwal, Komal Raina
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7304.
https://doi.org/10.1158/1538-7445.AM2024-7304
Published: 22 March 2024
View articletitled, Abstract 7304: Modulation of cytokine and chemokine profiles in pancreatic tumors and plasma via stage-specific intervention with Momordica Charantia juice in the LSL-KrasG12D/+, p48Cre/+ mouse model
Journal Articles

Abstract 7310: Dietary feeding of silibinin effectively protects against UVB-induced basal cell carcinoma

Sandeep Paudel, Neha Mishra, Komal Raina, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7310.
https://doi.org/10.1158/1538-7445.AM2024-7310
Published: 22 March 2024
View articletitled, Abstract 7310: Dietary feeding of silibinin effectively protects against UVB-induced basal cell carcinoma
Journal Articles

Abstract 7307: Silibinin regulates glucocorticoid signaling via mast cells: Potential treatment of androgen-resistant prostate cancer

Neha Mishra, Sandeep Paudel, Komal Raina, Paul Maroni, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7307.
https://doi.org/10.1158/1538-7445.AM2024-7307
Published: 22 March 2024
View articletitled, Abstract 7307: Silibinin regulates glucocorticoid signaling via mast cells: Potential treatment of androgen-resistant prostate cancer
Journal Articles

Abstract 5271: Inhibition of ultraviolet B radiation-induced mast cell recruitment by silibinin in its efficacy against basal cell carcinoma in Ptch+/− mouse model

Sandeep Paudel, Neha Mishra, Komal Raina, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5271.
https://doi.org/10.1158/1538-7445.AM2023-5271
Published: 04 April 2023
View articletitled, Abstract 5271: Inhibition of ultraviolet B radiation-induced mast cell recruitment by silibinin in its efficacy against basal cell carcinoma in Ptch+/− mouse model
Journal Articles

Abstract 5270: Silibinin modulates migration and survival pathways in bone marrow mast cells via RAC2: Implications in its anti-cancer activity in basal cell carcinoma growth and progression

Neha Mishra, Sandeep Paudel, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5270.
https://doi.org/10.1158/1538-7445.AM2023-5270
Published: 04 April 2023
View articletitled, Abstract 5270: Silibinin modulates migration and survival pathways in bone marrow mast cells via RAC2: Implications in its anti-cancer activity in basal cell carcinoma growth and progression
Journal Articles

Abstract 718: Significantly strong protective efficacy of silibinin against basal cell carcinoma growth and progression

Sandeep Paudel, Komal Raina, Vasundhara R. Tiku, Akhilendra Maurya, David J. Orlicky, Zhiying You, Cindy M. Rigby, Gagan Deep, Rama Kant, Bupinder Raina, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 718.
https://doi.org/10.1158/1538-7445.AM2022-718
Published: 15 June 2022
View articletitled, Abstract 718: Significantly strong protective efficacy of silibinin against basal cell carcinoma growth and progression
Journal Articles

Abstract 716: Silibinin: A novel potential therapeutic agent against UVB-induced basal cell carcinoma

Komal Raina, Sandeep Paudel, Neha Mishra, Sushil Kumar, David J. Orlicky, Zhiying You, Rama Kant, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 716.
https://doi.org/10.1158/1538-7445.AM2022-716
Published: 15 June 2022
View articletitled, Abstract 716: Silibinin: A novel potential therapeutic agent against UVB-induced basal cell carcinoma
Journal Articles

Abstract 5088: Silibinin inhibits UVB-induced promotion and progression of microscopic basal cell carcinoma formation via targeting bone morphogenic protein 2

Cynthia M. Rigby, Gagan Deep, Anil K. Jain, David J. Orlicky, Chapla Agarwal, Komal Raina, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5088.
https://doi.org/10.1158/1538-7445.AM2019-5088
Published: 01 July 2019
View articletitled, Abstract 5088: Silibinin inhibits UVB-induced promotion and progression of microscopic basal cell carcinoma formation via targeting bone morphogenic protein 2
Journal Articles

Abstract 5078: Modulation of glucose metabolism and lactate efflux in tumors by bitter melon juice in its efficacy against pancreatic cancer

Deepanshi Dhar, Rama Kant, Komal Raina, Michael F. Wempe, Natalie J. Serkova, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5078.
https://doi.org/10.1158/1538-7445.AM2019-5078
Published: 01 July 2019
View articletitled, Abstract 5078: Modulation of glucose metabolism and lactate efflux in tumors by bitter melon juice in its efficacy against pancreatic cancer
Journal Articles

Abstract 2123: A combinatorial approach using gemcitabine and bitter melon juice overcomes drug resistance impacting gemcitabine uptake and metabolism

Deepanshi Dhar, Dileep Kumar, Komal Raina, David J. Orlicky, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2123.
https://doi.org/10.1158/1538-7445.AM2019-2123
Published: 01 July 2019
View articletitled, Abstract 2123: A combinatorial approach using gemcitabine and bitter melon juice overcomes drug resistance impacting gemcitabine uptake and metabolism
Journal Articles

Abstract 1268: Bitter melon efficacy against human pancreatic cancer cells: possible involvement of cellular stemness and metabolome targets

Deepanshi Dhar, Gagan Deep, Sushil Kumar, Chapla Agarwal, Natalie Serkova, Michael Wempe, Komal Raina, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1268.
https://doi.org/10.1158/1538-7445.AM2017-1268
Published: 01 July 2017
View articletitled, Abstract 1268: Bitter melon efficacy against human pancreatic cancer cells: possible involvement of cellular stemness and metabolome targets
Journal Articles

Abstract 1249: Procyanidin B2-3,3′-di-O-gallate targets cancer cell metabolism in its efficacy against human prostate carcinoma cells

Chapla Agarwal, Dileep Kumar, Alpna Tyagi, Natalie Serkova, Michael Wempe, Komal Raina, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1249.
https://doi.org/10.1158/1538-7445.AM2017-1249
Published: 01 July 2017
View articletitled, Abstract 1249: Procyanidin B2-3,3′-di-O-gallate targets cancer cell metabolism in its efficacy against human prostate carcinoma cells
Journal Articles

Abstract 5236: Bitter melon juice causes strong efficacy towards pancreatic cancer stem cells by modulating the hedgehog signaling pathway

Rajesh Agarwal, Deepanshi Dhar, Chapla Agarwal, Gagan Deep
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5236.
https://doi.org/10.1158/1538-7445.AM2016-5236
Published: 15 July 2016
View articletitled, Abstract 5236: Bitter melon juice causes strong efficacy towards pancreatic cancer stem cells by modulating the hedgehog signaling pathway
Journal Articles

Abstract 901: Grape seed extract decreases visceral adiposity and impairs the pro-tumorigenic adipose tissue secretions affecting colorectal cancer growth and progression

Komal Raina, Sushil Kumar, Dileep Kumar, Ranganatha R. Somasagara, Reenu Punia, Rama Kant, Rajesh Agarwal, Chapla Agarwal
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 901.
https://doi.org/10.1158/1538-7445.AM2015-901
Published: 01 August 2015
View articletitled, Abstract 901: Grape seed extract decreases visceral adiposity and impairs the pro-tumorigenic adipose tissue secretions affecting colorectal cancer growth and progression
Journal Articles

Abstract 2807: Oral silibinin inhibits tumorigenic potential of colon cancer stem cells

Sushil Kumar, Dileep Kumar, Komal Raina, Natalie J. Serkova, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2807.
https://doi.org/10.1158/1538-7445.AM2015-2807
Published: 01 August 2015
View articletitled, Abstract 2807: Oral silibinin inhibits tumorigenic potential of colon cancer stem cells
Journal Articles

Abstract 4116: Grape seed extract impairs adipocyte-colorectal cancer cell interaction and decreases adipocyte-driven colon cancer stem colonosphere formation

Sushil Kumar, Dileep Kumar, Komal Raina, Rajesh Agarwal, Chapla Agarwal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4116.
https://doi.org/10.1158/1538-7445.AM2014-4116
Published: 01 October 2014
View articletitled, Abstract 4116: Grape seed extract impairs adipocyte-colorectal cancer cell interaction and decreases adipocyte-driven colon cancer stem colonosphere formation
Journal Articles

Abstract 698A: Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells

Ranganatha Somasagara, Gagan Deep, Sangeeta Shrotriya, Manisha Patel, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 698A.
https://doi.org/10.1158/1538-7445.AM2014-698A
Published: 01 October 2014
View articletitled, Abstract 698A: Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells
Journal Articles

Abstract 4114: Silibinin inhibits hypoxia-induced proliferation, angiogenesis and lipogenesis in prostate cancer cells both in vitro and in vivo

Gagan Deep, Anand M. Ramteke, Dhanya K. Nambiar, Anil K. Jain, Natalie J. Serkova, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4114.
https://doi.org/10.1158/1538-7445.AM2014-4114
Published: 01 October 2014
View articletitled, Abstract 4114: Silibinin inhibits hypoxia-induced proliferation, angiogenesis and lipogenesis in prostate cancer cells both in vitro and in vivo
Journal Articles

Abstract 1012: Procyanidin B2 3,3″-di-O-gallate (B2G2), a biologically active constituent of grape seed extract, inhibits angiogenesis targeting multiple molecular pathways

Rahul Kumar, Gagan Deep, Michael Wempe, Rajesh Agarwal, Chapla Agarwal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1012.
https://doi.org/10.1158/1538-7445.AM2014-1012
Published: 01 October 2014
View articletitled, Abstract 1012: Procyanidin B2 3,3″-di-O-gallate (B2G2), a biologically active constituent of grape seed extract, inhibits angiogenesis targeting multiple molecular pathways
Journal Articles

Abstract 2452: Silibinin inhibits lipid metabolism by primarily targeting the master regulator sterol response element binding protein 1 (SREBP1) in prostate cancer cells

Dhanya K. Nambiar, Gagan Deep, Rana P. Singh, Chapla Agarwal, Rajesh Agarwal
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2452.
https://doi.org/10.1158/1538-7445.AM2014-2452
Published: 01 October 2014
View articletitled, Abstract 2452: Silibinin inhibits lipid metabolism by primarily targeting the master regulator sterol response element binding protein 1 (SREBP1) in prostate cancer cells