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Journal Articles

Clonal Mutations Activate the NF-κB Pathway to Promote Recurrence of Nasopharyngeal Carcinoma

Free
Rui You, You-Ping Liu, De-Chen Lin, Qing Li, Tao Yu, Xiong Zou, Mei Lin, Xiao-Long Zhang, Gui-Ping He, Qi Yang, Yi-Nuan Zhang, Yu-Long Xie, Rou Jiang, Chen-Yan Wu, Chao Zhang, Cheng Cui, Jing-Qi Wang, Yue Wang, Ai-Hua Zhuang, Gui-Fang Guo, Yi-Jun Hua, Rui Sun, Jing-Ping Yun, Zhi-Xiang Zuo, Ze-Xian Liu, Xiao-Feng Zhu, Tie-Bang Kang, Chao-Nan Qian, Hai-Qiang Mai, Ying Sun, Mu-Sheng Zeng, Lin Feng, Yi-Xin Zeng, Ming-Yuan Chen
Journal: Cancer Research
Cancer Res (2019) 79 (23): 5930–5943.
https://doi.org/10.1158/0008-5472.CAN-18-3845
Published: 02 December 2019
View article titled, Clonal Mutations Activate the NF-κB Pathway to Promote Recurrence of Nasopharyngeal Carcinoma
Open the PDF for Clonal Mutations Activate the NF-κB Pathway to Promote Recurrence of Nasopharyngeal Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 201: The mechanism of vascular mimicry in clear cell renal cell cancer

Free
Jun-Ping Yang, Xing-Si Peng, Chao-Nan Qian
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 201.
https://doi.org/10.1158/1538-7445.AM2019-201
Published: 01 July 2019
View article titled, Abstract 201: The mechanism of vascular mimicry in clear cell renal cell cancer
Journal Articles

Abstract 1124: S100A14 suppresses metastasis of nasopharyngeal carcinoma via inhibition of NF-kB signaling

Free
Dong-Fang Meng, Chao-Nan Qian
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1124.
https://doi.org/10.1158/1538-7445.AM2019-1124
Published: 01 July 2019
View article titled, Abstract 1124: S100A14 suppresses metastasis of nasopharyngeal carcinoma via inhibition of NF-kB signaling
Journal Articles

SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor

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Li-Sheng Zheng, Jun-Ping Yang, Yun Cao, Li-Xia Peng, Rui Sun, Ping Xie, Meng-Yao Wang, Dong-Fang Meng, Dong-Hua Luo, Xiong Zou, Ming-Yuan Chen, Hai-Qiang Mai, Ling Guo, Xiang Guo, Jian-Yong Shao, Bi-Jun Huang, Wei Zhang, Chao-Nan Qian
Journal: Cancer Research
Cancer Res (2017) 77 (2): 579–589.
https://doi.org/10.1158/0008-5472.CAN-16-1281
Published: 16 January 2017
View article titled, SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor
Open the PDF for SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor in another window
Includes: Supplementary data
Journal Articles

Abstract 3360: EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngealcarcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loop

Free
Chang-Fu Yang, Guang-Da Yang, Tie-Jun Huang, Jia-Ling Huang, Chao-Nan Qian, Bi-Jun Huang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3360.
https://doi.org/10.1158/1538-7445.AM2016-3360
Published: 15 July 2016
View article titled, Abstract 3360: EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngealcarcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loop
Journal Articles

Abstract 1622: Dovitinib preferentially targets endothelial cells rather than cancer cells for the inhibition of hepatocellular carcinoma growth and metastasis.

Free
Zhi-Yuan Chen, Ming Shi, Li-Xia Peng, Wei Wei, Xin-Jian Li, Zhi-Xing Guo, Shu-Hong Li, Chong Zhong, Chao-Nan Qian, Rong-Ping Guo
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1622.
https://doi.org/10.1158/1538-7445.AM2013-1622
Published: 15 April 2013
View article titled, Abstract 1622: Dovitinib preferentially targets endothelial cells rather than cancer cells for the inhibition of hepatocellular carcinoma growth and metastasis.
Journal Articles

Abstract 1225: Serum cytokine profiling in metastatic colorectal cancer patients: IL-8, MCP-1, and MCP-3 are theranostic targets.

Free
Zhi-Yuan Chen, Wen-Zhuo He, Li-Xia Peng, Rong-Ping Guo, Liang-Ping Xia, Chao-Nan Qian
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1225.
https://doi.org/10.1158/1538-7445.AM2013-1225
Published: 15 April 2013
View article titled, Abstract 1225: Serum cytokine profiling in metastatic colorectal cancer patients: IL-8, MCP-1, and MCP-3 are theranostic targets.
Journal Articles

Abstract 4378: Pericyte coverage of differentiated vessels inside tumor vasculature is an independent unfavorable prognostic factor for patients with clear cell renal cell carcinoma

Free
Yun Cao, Zhi-Ling Zhang, Ming Zhou, Paul Elson, Brian Rini, Hakan Aydin, Kristin Feenstra, Min-Han Tan, Bree Berghuis, Rebeka Tabbey, James Resau, Fang-Jian Zhou, Bin Tean Teh, Chao-Nan Qian
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4378.
https://doi.org/10.1158/1538-7445.AM2012-4378
Published: 15 April 2012
View article titled, Abstract 4378: Pericyte coverage of differentiated vessels inside tumor vasculature is an independent unfavorable prognostic factor for patients with clear cell renal cell carcinoma
Journal Articles

Abstract 1476: Serglycin in nasopharyngeal carcinoma: A metastasis regulator and prognostic indicator

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Xin-Jian Li, Choon Kiat Ong, Yun Cao, Jian-Yong Shao, Aikseng Ooi, Li-Xia Peng, Wen-Hua Lu, Zhongfa Zhang, David Petillo, Li Qin, Ying-Na Bao, Fang-Jing Zheng, Claramae Shulyn Chia, N. Gopalakrishna Iyer, Tie-Bang Kang, Yi-Xin Zeng, Khee Chee Soo, Jeffrey Trent, Bin Tean Teh, Chao-Nan Qian
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1476.
https://doi.org/10.1158/1538-7445.AM2011-1476
Published: 15 April 2011
View article titled, Abstract 1476: Serglycin in nasopharyngeal carcinoma: A metastasis regulator and prognostic indicator
Journal Articles

Abstract 494: Stemness characteristics contribute to metastasis and shorter patient survival in nasopharyngeal carcinoma

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Fang-Jing Zheng, Li Qin, Yi Liang, Xin-Jian Li, Li-Xi Peng, Wen-Hua Lu, Ying-Na Bao, Tie-Bang Kang, Yi-Xin Zeng, Jeffrey M. Trent, Chao-Nan Qian
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 494.
https://doi.org/10.1158/1538-7445.AM2011-494
Published: 15 April 2011
View article titled, Abstract 494: Stemness characteristics contribute to metastasis and shorter patient survival in nasopharyngeal carcinoma
Journal Articles

Abstract 57: Integrating transcriptome profiling and in silico pathway analysis toward reduction of therapeutic dimensionality in nasopharyngeal carcinoma

Free
Ying-Na Bao, Yilin Dai, Yongpan Yan, Wen-Hua Lu, Li-Xia Peng, Fang-Jing Zheng, Xin-Jian Li, Tie-Bang Kang, Yi-Xin Zeng, Jeffrey M. Trent, Chao-Nan Qian
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 57.
https://doi.org/10.1158/1538-7445.AM2011-57
Published: 15 April 2011
View article titled, Abstract 57: Integrating transcriptome profiling and in silico pathway analysis toward reduction of therapeutic dimensionality in nasopharyngeal carcinoma
Journal Articles

Serglycin Is a Theranostic Target in Nasopharyngeal Carcinoma that Promotes Metastasis

Free
Xin-Jian Li, Choon Kiat Ong, Yun Cao, Yan-Qun Xiang, Jian-Yong Shao, Aikseng Ooi, Li-Xia Peng, Wen-Hua Lu, Zhongfa Zhang, David Petillo, Li Qin, Ying-Na Bao, Fang-Jing Zheng, Claramae Shulyn Chia, N. Gopalakrishna Iyer, Tie-Bang Kang, Yi-Xin Zeng, Khee Chee Soo, Jeffrey M. Trent, Bin Tean Teh, Chao-Nan Qian
Journal: Cancer Research
Cancer Res (2011) 71 (8): 3162–3172.
https://doi.org/10.1158/0008-5472.CAN-10-3557
Published: 13 April 2011
View article titled, Serglycin Is a Theranostic Target in Nasopharyngeal Carcinoma that Promotes Metastasis
Open the PDF for Serglycin Is a Theranostic Target in Nasopharyngeal Carcinoma that Promotes Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 1644: Sunitinib primarily acts on tumor endothelium but not tumor cells to inhibit renal cell carcinoma tumor growth

Free
Dan Huang, Yan Ding, Yan Li, Wang-Mei Luo, Zhong-Fa Zhang, John Snider, Kristin VandenBeldt, Chao-Nan Qian, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1644.
https://doi.org/10.1158/1538-7445.AM10-1644
Published: 15 April 2010
View article titled, Abstract 1644: Sunitinib primarily acts on tumor endothelium but not tumor cells to inhibit renal cell carcinoma tumor growth
Journal Articles

Abstract 2238: A novel prognostic marker in patients with squamous cell carcinoma of the tongue: high endothelial venules

Free
Ser Yee Lee, Aik Seng Ooi, Chao-Nan Qian, Siok Gek Hwang, Bin Tean Teh, Khee-Chee Soo
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2238.
https://doi.org/10.1158/1538-7445.AM10-2238
Published: 15 April 2010
View article titled, Abstract 2238: A novel prognostic marker in patients with squamous cell carcinoma of the tongue: high endothelial venules
Journal Articles

Abstract 630: Interleukin-8 as a potential mediator for renal cell carcinoma resistance to antiangiogenic sunitinib therapy

Free
Dan Huang, Yan Ding, Ming Zhou, Brian Rini, David Petillo, Chao-Nan Qian, Richard Kahnoski, P. Andrew Futreal, Kyle A. Furge, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 630.
https://doi.org/10.1158/1538-7445.AM10-630
Published: 15 April 2010
View article titled, Abstract 630: Interleukin-8 as a potential mediator for renal cell carcinoma resistance to antiangiogenic sunitinib therapy
Journal Articles

Abstract 3314: Side population in renal cell carcinoma cell line is enriched with drug resistant, but not tumor initiating cells

Free
Choon Kiat Ong, Bernice Hui Min Wong, Jacey Jing Chii Wong, Da Chuan Huang, Aik Seng Ooi, Miles Chao Nan Qian, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3314.
https://doi.org/10.1158/1538-7445.AM10-3314
Published: 15 April 2010
View article titled, Abstract 3314: Side population in renal cell carcinoma cell line is enriched with drug resistant, but not tumor initiating cells
Journal Articles

Sunitinib Acts Primarily on Tumor Endothelium rather than Tumor Cells to Inhibit the Growth of Renal Cell Carcinoma

Free
Dan Huang, Yan Ding, Yan Li, Wang-Mei Luo, Zhong-Fa Zhang, John Snider, Kristin VandenBeldt, Chao-Nan Qian, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2010) 70 (3): 1053–1062.
https://doi.org/10.1158/0008-5472.CAN-09-3722
Published: 31 January 2010
View article titled, Sunitinib Acts Primarily on Tumor Endothelium rather than Tumor Cells to Inhibit the Growth of Renal Cell Carcinoma
Open the PDF for Sunitinib Acts Primarily on Tumor Endothelium rather than Tumor Cells to Inhibit the Growth of Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma

Free
Dan Huang, Yan Ding, Ming Zhou, Brian I. Rini, David Petillo, Chao-Nan Qian, Richard Kahnoski, P. Andrew Futreal, Kyle A. Furge, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2010) 70 (3): 1063–1071.
https://doi.org/10.1158/0008-5472.CAN-09-3965
Published: 31 January 2010
View article titled, Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Activation of the PI3K/AKT Pathway Induces Urothelial Carcinoma of the Renal Pelvis: Identification in Human Tumors and Confirmation in Animal Models

Free
Chao-Nan Qian, Kyle A. Furge, Jared Knol, Dan Huang, Jindong Chen, Karl J. Dykema, Eric J. Kort, Aaron Massie, Sok Kean Khoo, Kristin Vanden Beldt, James H. Resau, John Anema, Richard J. Kahnoski, Hans Morreau, Philippe Camparo, Eva Comperat, Mathilde Sibony, Yves Denoux, Vincent Molinie, Annick Vieillefond, Charis Eng, Bart O. Williams, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2009) 69 (21): 8256–8264.
https://doi.org/10.1158/0008-5472.CAN-09-1689
Published: 28 October 2009
View article titled, Activation of the PI3K/AKT Pathway Induces Urothelial Carcinoma of the Renal Pelvis: Identification in Human Tumors and Confirmation in Animal Models
Open the PDF for Activation of the PI3K/AKT Pathway Induces Urothelial Carcinoma of the Renal Pelvis: Identification in Human Tumors and Confirmation in Animal Models in another window
Includes: Supplementary data
Journal Articles

Abstract #2765: The Role of MAPK13 in Cholangiocarcinoma

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Aikseng Ooi, Dachuan Huang, Felicia Tan Li-Sher, Jacey Wong, Zhongfa Zhang, Cora Chao, London Ooi, Yu-Meng Tan, Alexander Chung, Peng-Chung Cheow, David Petillo, Chao-Nan Qian, Khee-Chee Soo, Bin Teh
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2765.
Published: 01 May 2009
View article titled, Abstract #2765: The Role of MAPK13 in Cholangiocarcinoma