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Journal Articles

Abstract 1208: The neuroimmune impact of chronic stress on triple-negative breast cancer

Free
Chao Zhang, Lizhong Wang, Runhua Liu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1208.
https://doi.org/10.1158/1538-7445.AM2025-1208
Published: 21 April 2025
View articletitled, Abstract 1208: The neuroimmune impact of chronic stress on triple-negative breast cancer
Journal Articles

Abstract 5637: A novel KIF18A inhibitor for targeting chromosomal instability in cancer

Free
Lana Kulyk, Shawn Wright, Jill Hallin, Michael Maestre, Joseph Dennis, Iriny Botrous, Anders S. Christensen, Jan Pencik, Craig Gutierrez, Afsheen Banisadr, Jeeyoung Park, Abby Adams, Chang Zhao, Kelly Chen, Stephen Munoz, Shane Yost, Marcelo Lacerda, Angus Voice, Mary L. Anderson, Bo Liu, Matt Welborn, Chao Zhang, Jeff Hager, Fred Manby, Tom Miller, Hui Zhang, Laurent Gomez, Peter Olson, Zhongdong Huang, Chunmei Zhao
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5637.
https://doi.org/10.1158/1538-7445.AM2025-5637
Published: 21 April 2025
View articletitled, Abstract 5637: A novel KIF18A inhibitor for targeting chromosomal instability in cancer
Journal Articles

Abstract 6402: Stress-induced HDAC8 reprogramming drives IL-11-mediated immune escape in melanoma

Free
Michael F. Emmons, Chao Zhang, Zhihua Chen, Richard L. Bennett, Olga Vera, Manali S. Phadke, Kanchan Gupta, Florian A. Karreth, Jonathan D. Licht, Keiran S. Smalley
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6402.
https://doi.org/10.1158/1538-7445.AM2025-6402
Published: 21 April 2025
View articletitled, Abstract 6402: Stress-induced HDAC8 reprogramming drives IL-11-mediated immune escape in melanoma
Journal Articles

Abstract 5186: Organoids from patient-derived xenograft (PDXO) for preclinical therapeutic predictions

Free
Chao Zhang, Xiaoying Zhuang, Lu Yin, Xiaoyi Xing, Sen Wang, Zizhuo Chen, Lei Jin, Qiangqiang Fan, Jiaping Sun, Fuyang Wang, Wenjie Gao, Qingyang Gu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5186.
https://doi.org/10.1158/1538-7445.AM2025-5186
Published: 21 April 2025
View articletitled, Abstract 5186: Organoids from patient-derived xenograft (PDXO) for preclinical therapeutic predictions
Journal Articles

Abstract 660: OPN-6602, a potent dual EP300/CBP bromodomain inhibitor, targets multiple myeloma through concomitant suppression of IRF4 and c-MYC

Free
Bernice Matusow, Wayne Spevak, Chao Zhang, Yan Ma, Rafe Shellooe, James Tsai, Pei Pei Li, Pan Yu Chen, Gaston Habets, Christine Nichols, Parmveer Singh, Kerry Inokuchi, Jackie Walling, Jason Halladay, Gideon Bollag
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 660.
https://doi.org/10.1158/1538-7445.AM2024-660
Published: 22 March 2024
View articletitled, Abstract 660: OPN-6602, a potent dual EP300/CBP bromodomain inhibitor, targets multiple myeloma through concomitant suppression of IRF4 and c-MYC
Journal Articles

Abstract 1980: Validation of a novel Type II HER2 inhibitor through preclinical studies across various cancer models

Free
Lana Kulyk, Kelly Chen, Iriny Botrous, Chunmei Zhao, Chang Zhao, Michael Maestre, Shawn Wright, Joseph Dennis, Jeeyoung Park, Abby Adams, Wallace Derricotte, Shane Yost, Mary L. Anderson, Fred Manby, Tom Miller, Chao Zhang, Laurent Gomez, Zhongdong Huang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1980.
https://doi.org/10.1158/1538-7445.AM2024-1980
Published: 22 March 2024
View articletitled, Abstract 1980: Validation of a novel Type II HER2 inhibitor through preclinical studies across various cancer models
Journal Articles

Abstract 2507: Chronic stress promotes tumor progression and metastasis through the tumor microenvironment in triple-negative breast cancer

Free
Chao Zhang, Lizhong Wang, Runhua Liu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2507.
https://doi.org/10.1158/1538-7445.AM2023-2507
Published: 04 April 2023
View articletitled, Abstract 2507: Chronic stress promotes tumor progression and metastasis through the tumor microenvironment in triple-negative breast cancer
Journal Articles

Abstract 3345: Tissue of origin (TOO) localization using targeted methylation biomarkers discovered by whole-genome bisulfite sequencing

Free
Qiang Wei, Wanglong Deng, Zhihui Xu, Yihui Han, Yuan Yang, Chao Zhang, Xiaoqiang Wang, Xuan Tang, Chao Song, Qing Xu, Yong Ren
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3345.
https://doi.org/10.1158/1538-7445.AM2023-3345
Published: 04 April 2023
View articletitled, Abstract 3345: Tissue of origin (TOO) localization using targeted methylation biomarkers discovered by whole-genome bisulfite sequencing
Journal Articles

Abstract 3465: HDAC8 regulates immune escape in melanoma through increased transcription of inhibitory cytokines that increase accumulation of myeloid-derived suppressor cells (MDSCs)

Free
Chao Zhang, Michael Emmons, Richard Bennett, Jonathan Licht, Keiran Smalley
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3465.
https://doi.org/10.1158/1538-7445.AM2023-3465
Published: 04 April 2023
View articletitled, Abstract 3465: HDAC8 regulates immune escape in melanoma through increased transcription of inhibitory cytokines that increase accumulation of myeloid-derived suppressor cells (MDSCs)
Journal Articles

Abstract 4034: A potent and highly selective irreversible HER2 inhibitor for treating HER2-driven cancers

Free
Chunmei Zhao, Lana Kulyk, Iriny Botrous, Kelly Chen, Chang Zhao, Afsheen Banisadr, Mary L. Anderson, Fred Manby, Tom Miller, Chao Zhang, Laurent Gomez, Zhongdong Huang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4034.
https://doi.org/10.1158/1538-7445.AM2023-4034
Published: 04 April 2023
View articletitled, Abstract 4034: A potent and highly selective irreversible HER2 inhibitor for treating HER2-driven cancers
Journal Articles

Abstract 3606: HDAC8-mediated inhibition of EP300 drives a neural crest-like transcriptional state that increases melanoma brain metastasis

Free
Michael Emmons, Richard Bennett, Alberto Riva, Chao Zhang, Robert Macaulay, Daphne Dupéré-Richér, Bin Fang, John Koomen, Jiannong Li, Ann Chen, Edward Seto, Jonathan Licht, Keiran Smalley
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3606.
https://doi.org/10.1158/1538-7445.AM2023-3606
Published: 04 April 2023
View articletitled, Abstract 3606: HDAC8-mediated inhibition of EP300 drives a neural crest-like transcriptional state that increases melanoma brain metastasis
Journal Articles

Abstract 2293: Tumor-informed fixed and patient-specific panels for minimal residual disease (MRD) detection in early-stage NSCLC:a head-to-head comparison

Free
Pengpeng Zhang, Zetian Gong, Yue Yu, Xiaoxuan Wang, Lei Ye, Xiaoqiang Wang, Xuan Tang, Chao Zhang, Wanglong Deng, Chao Song, Qing Xu, Yansong Li, Wei Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2293.
https://doi.org/10.1158/1538-7445.AM2023-2293
Published: 04 April 2023
View articletitled, Abstract 2293: Tumor-informed fixed and patient-specific panels for minimal residual disease (MRD) detection in early-stage NSCLC:a head-to-head comparison
Journal Articles

Abstract 6604: Analytical development and validation of a personalized hybrid capture based assay for high sensitivity monitoring minimal residual disease (MRD)

Free
Xiaoqiang Wang, Lei Ye, Chao Zhang, Wanglong Deng, Yongjie Wei, Jing Chen, Xuan Tang, Xiaoxuan Wang, Chao Song, Qing Xu, Yong Ren
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6604.
https://doi.org/10.1158/1538-7445.AM2023-6604
Published: 04 April 2023
View articletitled, Abstract 6604: Analytical development and validation of a personalized hybrid capture based assay for high sensitivity monitoring minimal residual disease (MRD)
Journal Articles

Correction: YY1 Complex Promotes Quaking Expression via Super-Enhancer Binding during EMT of Hepatocellular Carcinoma

Free
Jingxia Han, Jing Meng, Shuang Chen, Xiaorui Wang, Shan Yin, Qiang Zhang, Huijuan Liu, Rong Qin, Zhongwei Li, Weilong Zhong, Chao Zhang, Heng Zhang, Yuanhao Tang, Wanfeng Gao, Xiaoyun Zhang, Lan Yang, Yanrong Liu, Hong-gang Zhou, Tao Sun, Cheng Yang
Journal: Cancer Research
Cancer Res (2022) 82 (24): 4694.
https://doi.org/10.1158/0008-5472.CAN-22-3444
Published: 16 December 2022
View articletitled, Correction: YY1 Complex Promotes Quaking Expression via Super-Enhancer Binding during EMT of Hepatocellular Carcinoma
Open the PDF for Correction: YY1 Complex Promotes Quaking Expression via Super-Enhancer Binding during EMT of Hepatocellular Carcinoma in another window
Journal Articles

Abstract 89: The microRNA-3622b-3p contributes to tumor progression and metastasis through an miR-3622-AIFM2 axis in prostate cancer

Free
Lizhong Wang, Chao Zhang, Ping Ye
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 89.
https://doi.org/10.1158/1538-7445.AM2022-89
Published: 15 June 2022
View articletitled, Abstract 89: The microRNA-3622b-3p contributes to tumor progression and metastasis through an miR-3622-AIFM2 axis in prostate cancer
Journal Articles

Abstract 5988: Intra-carotid artery brain metastasis models for evaluation of lung and breast cancer drugs

Free
Fuyang Wang, Yuying Yang, Haoxia Zhao, Chunlei Dai, Bingrui Han, Mengyao Zhang, Xia Xiong, Chao Zhang, Xuzhen Tang, Qunsheng Ji
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5988.
https://doi.org/10.1158/1538-7445.AM2022-5988
Published: 15 June 2022
View articletitled, Abstract 5988: Intra-carotid artery brain metastasis models for evaluation of lung and breast cancer drugs
Journal Articles

Abstract 6015: Comprehensive evaluation of three-dimensional (3D) culture systems as compound screening platforms with primary cancer cell lines

Free
Chao Zhang, Qinghua Wu, Lei Jin, Deyin Chen, Xuzhen Tang, Hui Qi, Wenjie Gao, Qunsheng Ji
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6015.
https://doi.org/10.1158/1538-7445.AM2022-6015
Published: 15 June 2022
View articletitled, Abstract 6015: Comprehensive evaluation of three-dimensional (3D) culture systems as compound screening platforms with primary cancer cell lines
Journal Articles

The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers

Available to Purchase
Zhengjia Chen, Chao Zhang, Jianhong Chen, Dongsheng Wang, Jieqi Tu, Carter Van Waes, Nabil F. Saba, Zhuo G. Chen, Zhong Chen
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4402–4416.
https://doi.org/10.1158/0008-5472.CAN-20-3659
Published: 01 September 2021
View articletitled, The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers
Open the PDF for The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 321: Identification of proteins associated with FAT1 mutations which potentially contribute to oncogenesis and progression of head and neck cancers

Free
Zhuo Georgia Chen, Zhengjia Chen, Chao Zhang, Jianhong Chen, Dongsheng Wang, Nabil F. Saba, Zhong Chen
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 321.
https://doi.org/10.1158/1538-7445.AM2021-321
Published: 01 July 2021
View articletitled, Abstract 321: Identification of proteins associated with FAT1 mutations which potentially contribute to oncogenesis and progression of head and neck cancers
Journal Articles

Abstract 2011: HER2 expression and M2-like tumor infiltrating macrophages associated with Cabazitaxel activity in gastric cancer

Free
Sandipto Sarkar, Prashant K. Thakkar, Heinz Lenz, Peter Enzinger, Andrew H. Ko, Allyson J. Ocean, Yao Lu, Chao Zhang, Bhavneet Bhinder, Olga Plotnikova, Nikita Kotlov, Feliz Frenkel, Aleksander Bagaev, Olivier Elemento, Doron Betel, Paraskevi Giannakakou, Meredith E. Pittman, Manish A. Shah
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2011.
https://doi.org/10.1158/1538-7445.AM2020-2011
Published: 15 August 2020
View articletitled, Abstract 2011: HER2 expression and M2-like tumor infiltrating macrophages associated with Cabazitaxel activity in gastric cancer