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Journal Articles

Eco-evolutionary Guided Pathomic Analysis Detects Biomarkers to Predict Ductal Carcinoma In Situ Upstaging

Available to Purchase
Yujie Xiao, Manal Elmasry, Ji Dong K. Bai, Andrew Chen, Yuzhu Chen, Brooke Jackson, Joseph O. Johnson, Prateek Prasanna, Chao Chen, Mehdi Damaghi
Journal: Cancer Research
Cancer Res (2025)
https://doi.org/10.1158/0008-5472.CAN-24-2070
Published: 29 April 2025
View articletitled, Eco-evolutionary Guided Pathomic Analysis Detects Biomarkers to Predict Ductal Carcinoma In Situ Upstaging
Open the PDF for Eco-evolutionary Guided Pathomic Analysis Detects Biomarkers to Predict Ductal Carcinoma In Situ Upstaging in another window
Includes: Supplementary data
Journal Articles

Abstract PO1-15-02: Comprehensive characterization of genetic interactions in breast cancer reveals therapeutic vulnerabilities

Free
Caijin Lin, Xi Jin, Ding Ma, Chao Chen, Xin Hu, Yi-Zhou Jiang, Zhi-Ming Shao
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-15-02.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-15-02
Published: 02 May 2024
View articletitled, Abstract PO1-15-02: Comprehensive characterization of genetic interactions in breast cancer reveals therapeutic vulnerabilities
Journal Articles

Abstract B041: Keratin 17 excludes CD8-positive T cells and recruits CD163-positive macrophages in pancreatic ductal adenocarcinoma

Free
Lyanne Oblein, Sruthi Babu, Mariana Torrente-Goncalves, Lucia Roa, Michael Horowitz, Mahmudul Hasan, Danielle Fassler, Jaymie Oentoro, Emanuel Petricoin, Lynn M. Matrisian, Natalia Marchenko, Edik Blais, Felicia Allard, Ali Alkalin, Wei Jiang, Brent Larson, Andrew Hendifar, Chao Chen, Shahira Abousamra, Dimitris Samaras, Tahsin Kurc, Joel Saltz, Luisa Escobar-Hoyos, Kenneth Shroyer
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): B041.
https://doi.org/10.1158/1538-7445.PANCA2023-B041
Published: 16 January 2024
View articletitled, Abstract B041: Keratin 17 excludes CD8-positive T cells and recruits CD163-positive macrophages in pancreatic ductal adenocarcinoma
Journal Articles

Abstract 3801: Identification of circular RNAs associated with the ferroptosis of pancreatic cancer cells

Free
Jessica Jazmin Pena Paladines, Shao Weng Wang, Chi Hin Wong, Yang Chao Chen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3801.
https://doi.org/10.1158/1538-7445.AM2023-3801
Published: 04 April 2023
View articletitled, Abstract 3801: Identification of circular RNAs associated with the ferroptosis of pancreatic cancer cells
Journal Articles

Protein Phosphatase 1 Subunit PPP1R14B Stabilizes STMN1 to Promote Progression and Paclitaxel Resistance in Triple-Negative Breast Cancer

Open Access
Li Liao, Yin-Ling Zhang, Ling Deng, Chao Chen, Xiao-Yan Ma, Lisa Andriani, Shao-Ying Yang, Shu-Yuan Hu, Fang-Lin Zhang, Zhi-Min Shao, Da-Qiang Li
Journal: Cancer Research
Cancer Res (2023) 83 (3): 471–484.
https://doi.org/10.1158/0008-5472.CAN-22-2709
Published: 03 February 2023
View articletitled, Protein Phosphatase 1 Subunit PPP1R14B Stabilizes STMN1 to Promote Progression and Paclitaxel Resistance in Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Loss of FBXW7 Correlates with Increased IDH1 Expression in Glioma and Enhances IDH1-Mutant Cancer Cell Sensitivity to Radiation

Available to Purchase
Zhuo Yang, Nan Hu, Weiwei Wang, Weihua Hu, Shaolong Zhou, Jianxiang Shi, Minghe Li, Zhou Jing, Chao Chen, Xuyang Zhang, Ruyi Yang, Xudong Fu, Xinjun Wang
Journal: Cancer Research
Cancer Res (2022) 82 (3): 497–509.
https://doi.org/10.1158/0008-5472.CAN-21-0384
Published: 02 February 2022
View articletitled, Loss of FBXW7 Correlates with Increased IDH1 Expression in Glioma and Enhances IDH1-Mutant Cancer Cell Sensitivity to Radiation
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Includes: Supplementary data
Journal Articles

Abstract 3090: The MAT2A inhibitor, AG-270, combines with both taxanes and gemcitabine to yield enhanced anti-tumor activity in patient-derived xenograft models

Free
Marc L. Hyer, Peter Kalev, Mark Fletcher, Chi-Chao Chen, Elia Aguado-Fraile, Everton Mandley, Sheila Newhouse, Max Lein, Raj Nagaraja, Yesim Tuncay, Josh Murtie, Kevin M. Marks, Katya Marjon
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3090.
https://doi.org/10.1158/1538-7445.AM2020-3090
Published: 15 August 2020
View articletitled, Abstract 3090: The MAT2A inhibitor, AG-270, combines with both taxanes and gemcitabine to yield enhanced anti-tumor activity in patient-derived xenograft models
Journal Articles

Abstract NG06: CHD1-loss confers AR targeted therapy resistance via promoting cancer heterogeneity and lineage plasticity

Free
Zeda Zhang, Chuanli Zhou, Xiaoling Li, Spencer Barnes, Su Deng, Elizabeth Hoover, Chi-Chao Chen, Young Sun Lee, Choushi Wang, Carla Tirado, Lauren Metang, Nickolas Johnson, John Wongvipat, Kristina Navrazhina, Zhen Cao, Wassim Abida, Amaia Lujambio, Sheng Li, Vankat Malladi, Charles Sawyers, Ping Mu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): NG06.
https://doi.org/10.1158/1538-7445.AM2020-NG06
Published: 15 August 2020
View articletitled, Abstract NG06: CHD1-loss confers AR targeted therapy resistance via promoting cancer heterogeneity and lineage plasticity
Journal Articles

Abstract 4165: SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 and RB1 deficient prostate cancer

Free
Ping Mu, Zeda Zhang, Matteo Benelli, Wouter Karthaus, Elizebeth Hoover, Chi-Chao Chen, John Wongvipat, Sheng-Yu Ku, Dong Gao, Zhen Cao, Neel Shah, Elizabeth Adams, Wassim Abida, Philip Watson, Davide Prandi, Chun-Hao Huang, Elisa de Stanchina, Scott Lowe, Leigh Ellis, Himisha Beltran, Mark Rubin, David Goodrich, Francesca Demichelis, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4165.
https://doi.org/10.1158/1538-7445.AM2017-4165
Published: 01 July 2017
View articletitled, Abstract 4165: SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 and RB1 deficient prostate cancer
Journal Articles

Abstract 798: Label-free enrichment and detection of circulating tumor cells in metastatic breast cancer patients show 82% of cohorts have detectable targets

Free
Yu-Jen Chang, Chen-Lin Chen, Wei-Fan Hsu, Meng-Ze Li, Wei-Yuan Ma, Ken-Chao Chen, Guan-Syuan Huang, Wai-Sang Wong, Jhan-Yu Syu, Thomas, Yo-Yan Huang, Ching-Hung Lin, Andrew M. Wo, Chiun-Sheng Huang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 798.
https://doi.org/10.1158/1538-7445.AM2017-798
Published: 01 July 2017
View articletitled, Abstract 798: Label-free enrichment and detection of circulating tumor cells in metastatic breast cancer patients show 82% of cohorts have detectable targets
Journal Articles

Abstract 390: Impact of loss of IGF2 genomic imprinting on IGF1R signaling and cancer stem cell-associated biomarkers in gastric cancer

Free
Teng Chen, Ronghua Zhao, Qinsong Zuo, Chao Chen, Menfan Li, Dianxu Feng, Han Cai
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 390.
https://doi.org/10.1158/1538-7445.AM2014-390
Published: 01 October 2014
View articletitled, Abstract 390: Impact of loss of IGF2 genomic imprinting on IGF1R signaling and cancer stem cell-associated biomarkers in gastric cancer
Journal Articles

Telomere Shortening Is Associated with Genetic Anticipation in Chinese Von Hippel–Lindau Disease Families

Free
Xiang-hui Ning, Ning Zhang, Teng Li, Peng-jie Wu, Xi Wang, Xue-ying Li, Shuang-he Peng, Jiang-yi Wang, Jin-chao Chen, Kan Gong
Journal: Cancer Research
Cancer Res (2014) 74 (14): 3802–3809.
https://doi.org/10.1158/0008-5472.CAN-14-0024
Published: 14 July 2014
View articletitled, Telomere Shortening Is Associated with Genetic Anticipation in Chinese Von Hippel–Lindau Disease Families
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Journal Articles

Abstract 1077: Bufalin inhibited cell proliferation and expression of insulin-like growth factor 2 and type 1 receptor in human colorectal cancer cells

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Yong Zhang, Dian-Xu Feng, Ronghua Zhao, Chao Chen, Jie Wang, Qing-Song Zuo, Ya-Feng Chen, Xu Wang, Teng Chen
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1077.
https://doi.org/10.1158/1538-7445.AM2012-1077
Published: 15 April 2012
View articletitled, Abstract 1077: Bufalin inhibited cell proliferation and expression of insulin-like growth factor 2 and type 1 receptor in human colorectal cancer cells
Journal Articles

Abstract 1778: Anticancer activities and regulatory effects on apoptotic gene expression of Bufalin in the orthotopic transplantation model of human colorectal cancer in nude mice

Free
Jie Wang, Dian-Xu Feng, Chao Chen, Zhen-Hua Ni, Ronghua Zhao, Qing-Song Zuo, Ya-Feng Chen, Xu Wang, Yong Zhang, Alan G. Casson, Teng Chen
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1778.
https://doi.org/10.1158/1538-7445.AM2011-1778
Published: 15 April 2011
View articletitled, Abstract 1778: Anticancer activities and regulatory effects on apoptotic gene expression of Bufalin in the orthotopic transplantation model of human colorectal cancer in nude mice
Journal Articles

MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2

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Juan Lu, Ming-Liang He, Lu Wang, Ying Chen, Xiong Liu, Qi Dong, Yang-Chao Chen, Ying Peng, Kai-Tai Yao, Hsiang-Fu Kung, Xiang-Ping Li
Journal: Cancer Research
Cancer Res (2011) 71 (1): 225–233.
https://doi.org/10.1158/0008-5472.CAN-10-1850
Published: 02 January 2011
View articletitled, MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2
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Includes: Supplementary data
Journal Articles

Abstract 194: Loss of imprinting and abnormal expression of insulin-like growth factor II in gastric cancer

Free
Teng Chen, Qin-Song Zuo, Ronghua Zhao, Dian-Xu Feng, Chao Chen, Yi-Min Jiang, Marcia Cruz-Correa, Alan G. Casson, Feng Han
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 194.
https://doi.org/10.1158/1538-7445.AM10-194
Published: 15 April 2010
View articletitled, Abstract 194: Loss of imprinting and abnormal expression of insulin-like growth factor II in gastric cancer
Journal Articles

Silencing PinX1 Compromises Telomere Length Maintenance As Well As Tumorigenicity in Telomerase-Positive Human Cancer Cells

Free
Bin Zhang, Yun Xiu Bai, Hang Hang Ma, Feng Feng, Rui Jin, Zhi Long Wang, Jian Lin, Shi Peng Sun, Pingxun Yang, Xiao Xiong Wang, Pei Tang Huang, Cui Fen Huang, Ying Peng, Yang Chao Chen, Hsiang-fu Kung, Jun Jian Huang
Journal: Cancer Research
Cancer Res (2009) 69 (1): 75–83.
https://doi.org/10.1158/0008-5472.CAN-08-1393
Published: 31 December 2008
View articletitled, Silencing PinX1 Compromises Telomere Length Maintenance As Well As Tumorigenicity in Telomerase-Positive Human Cancer Cells
Open the PDF for Silencing PinX1 Compromises Telomere Length Maintenance As Well As Tumorigenicity in Telomerase-Positive Human Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Wnt/β-Catenin Signaling Contributes to Activation of Normal and Tumorigenic Liver Progenitor Cells

Free
Wen Yang, He-Xin Yan, Lei Chen, Qiong Liu, Ya-Qin He, Le-Xing Yu, Shu-Hui Zhang, Dan-Dan Huang, Liang Tang, Xiao-Ni Kong, Chao Chen, Shu-Qin Liu, Meng-Chao Wu, Hong-Yang Wang
Journal: Cancer Research
Cancer Res (2008) 68 (11): 4287–4295.
https://doi.org/10.1158/0008-5472.CAN-07-6691
Published: 02 June 2008
View articletitled, Wnt/β-Catenin Signaling Contributes to Activation of Normal and Tumorigenic Liver Progenitor Cells
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Includes: Supplementary data
Journal Articles

Mutation in the nm23 Gene Is Associated with Metastasis in Colorectal Cancer

Free
Liming Wang, Umesh Patel, Lagnajita Ghosh, Huan-Chao Chen, Sipra Banerjee
Journal: Cancer Research
Cancer Res (1993) 53 (4): 717–720.
Published: 01 February 1993
View articletitled, Mutation in the nm23 Gene Is Associated with Metastasis in Colorectal Cancer
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