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Chanjuan Shi
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Journal Articles

Abstract PR-14: Meta-analysis of spatial transcriptomics data from pancreatic cancer precursors proposes a common molecular framework for PanIN and IPMN

Matthew K Iyer, Ashley Fletcher, Elishama Kanu, Chanjuan Shi, Rosina Carr, Ahmed M. Elhossiny, Daniel P. Nussbaum, Eileen S. Carpenter, Marina Pasca di Magliano, Arul M. Chinnaiyan, Peter J. Allen, Timothy L. Frankel
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): PR-14.
https://doi.org/10.1158/1538-7445.PANCREATIC24-PR-14
Published: 15 September 2024
View article titled, Abstract PR-14: Meta-analysis of spatial transcriptomics data from pancreatic cancer precursors proposes a common molecular framework for PanIN and IPMN
Journal Articles

Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer

Nagaraj S. Nagathihalli, Jason A. Castellanos, Purushottam Lamichhane, Fanuel Messaggio, Chanjuan Shi, Xizi Dai, Priyamvada Rai, Xi Chen, Michael N. VanSaun, Nipun B. Merchant
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (21): 6235–6246.
https://doi.org/10.1158/0008-5472.CAN-18-0634
Published: 01 November 2018
View article titled, Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer
Open the PDF for Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer in another window
Journal Articles

Tobacco Carcinogen–Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer

Supriya Srinivasan, Tulasigeri Totiger, Chanjuan Shi, Jason Castellanos, Purushottam Lamichhane, Austin R. Dosch, Fanuel Messaggio, Nilesh Kashikar, Kumaraswamy Honnenahally, Yuguang Ban, Nipun B. Merchant, Michael VanSaun, Nagaraj S. Nagathihalli
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (21): 6146–6158.
https://doi.org/10.1158/0008-5472.CAN-18-0579
Published: 01 November 2018
View article titled, Tobacco Carcinogen–Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses

Kshipra Singh, Lori A. Coburn, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Chanjuan Shi, M. Kay Washington, Paula B. Luis, Claus Schneider, Alberto G. Delgado, M. Blanca Piazuelo, John L. Cleveland, Alain P. Gobert, Keith T. Wilson
Journal: Cancer Research
Cancer Res (2018) 78 (15): 4303–4315.
https://doi.org/10.1158/0008-5472.CAN-18-0116
Published: 31 July 2018
View article titled, Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses
Open the PDF for Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses in another window
Journal Articles

Abstract 1249: Animal model in the prevention of alcoholic pancreatitis

Supriya Srinivasan, Tulasigeri Totiger, Michael VanSaun, Fanuel Messaggio, Chanjuan Shi, Austin Dosch, Eric Nestler, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1249.
https://doi.org/10.1158/1538-7445.AM2018-1249
Published: 01 July 2018
View article titled, Abstract 1249: Animal model in the prevention of alcoholic pancreatitis
Journal Articles

Abstract 5042: CREB transgenic mice to study alcohol-associated pancreatic carcinogenesis

Tulasigeri Totiger, Supriya Srinivasan, Michael VanSaun, Chandrashekhar Joshi, Chanjuan Shi, Xizi Dai, Rajinder Dawra, Alexander Gaidarski, Eric Nestler, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5042.
https://doi.org/10.1158/1538-7445.AM2018-5042
Published: 01 July 2018
View article titled, Abstract 5042: CREB transgenic mice to study alcohol-associated pancreatic carcinogenesis
Journal Articles

Abstract A17: Molecular and clinicopathological features of native Nigerian colorectal cancer

David O. Irabor, Marilena Melas, Stephen B. Gruber, Chanjuan Shi, Leon Raskin
Journal: Cancer Research
Cancer Res (2017) 77 (22_Supplement): A17.
https://doi.org/10.1158/1538-7445.NEWFRONT17-A17
Published: 14 November 2017
View article titled, Abstract A17: Molecular and clinicopathological features of native Nigerian colorectal cancer
Journal Articles

Abstract 588: Advanced molecular characterization of severe autoimmune toxicities associated with checkpoint inhibitor therapies

Justin M. Balko, Daniel Y. Wang, Yu Wang, Rami Al-Rohil, Margaret Compton, Jeffery A. Sosman, Igor Puzanov, Bret Mobley, Robert D. Hoffman, Yaomin Xu, Javid J. Moslehi, Chanjuan Shi, Douglas B. Johnson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 588.
https://doi.org/10.1158/1538-7445.AM2017-588
Published: 01 July 2017
View article titled, Abstract 588: Advanced molecular characterization of severe autoimmune toxicities associated with checkpoint inhibitor therapies
Journal Articles

Abstract A16: Smad4 pathways modulate induction of the chemokine Ccl20 and repress inflammation-induced carcinogenesis in mouse colon

Anna L. Means, Tanner J. Freeman, Connie J. Weaver, Chanjuan Shi, Mary K. Washington, Bronson C. Wessinger, Tasia Brown, David K. Flaherty, Kevin P. Weller, Robert J. Coffey, Keith T. Wilson, Robert D. Beauchamp
Journal: Cancer Research
Cancer Res (2017) 77 (3_Supplement): A16.
https://doi.org/10.1158/1538-7445.CRC16-A16
Published: 31 January 2017
View article titled, Abstract A16: Smad4 pathways modulate induction of the chemokine Ccl20 and repress inflammation-induced carcinogenesis in mouse colon
Journal Articles

Abstract B71: Resistance to MEK inhibition in pancreatic cancer is associated with amphiregulin mediated EGFR-STAT3 activation

Nagaraj Nagathihalli, Jason Castellanos, Chanjuan Shi, Casey Roberts, Michael VanSaun, Nipun Merchant
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B71.
https://doi.org/10.1158/1538-7445.PANCA16-B71
Published: 14 December 2016
View article titled, Abstract B71: Resistance to MEK inhibition in pancreatic cancer is associated with amphiregulin mediated EGFR-STAT3 activation
Journal Articles

Abstract B19: Kras mutation imparts neoplastic potential on duct cells but not acinar cells in a mouse model of obstructive chronic pancreatitis

Fong C. Pan, Jessica N. Kim, Chanjuan Shi, Mary K. Washington, Maike Sander, Maureen Gannon, Robert D. Beauchamp, Christopher V. Wright, Anna L. Means
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B19.
https://doi.org/10.1158/1538-7445.PANCA16-B19
Published: 14 December 2016
View article titled, Abstract B19: Kras mutation imparts neoplastic potential on duct cells but not acinar cells in a mouse model of obstructive chronic pancreatitis
Journal Articles

Abstract B78: RAD51 sensitizes pancreatic cancer cells to AKT inhibition

Surpiya Srinivasan, Chanjuan Shi, Casey Roberts, Xizi Dai, Fanuel Messaggio, Krisztina Kovacs, Michael VanSaun, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B78.
https://doi.org/10.1158/1538-7445.PANCA16-B78
Published: 14 December 2016
View article titled, Abstract B78: RAD51 sensitizes pancreatic cancer cells to AKT inhibition
Journal Articles

Abstract 2618: Oncogenic mutant KRAS modulates CREB activation through MEK-ERK and AKT signaling in pancreatic cancer

Jason Castellanos, Supriya Srinivasan, Kumar Honnenahally, Chanjuan Shi, Michael VanSaun, David Robbins, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2618.
https://doi.org/10.1158/1538-7445.AM2016-2618
Published: 15 July 2016
View article titled, Abstract 2618: Oncogenic mutant KRAS modulates CREB activation through MEK-ERK and AKT signaling in pancreatic cancer
Journal Articles

Abstract 2000: Proteomic features of histological compartments in colorectal carcinoma

Robbert JC Slebos, Lisa J. Zimmerman, Suzanne Manning, Melinda E. Sanders, Chanjuan Shi, M Kay Washington, Daniel C. Liebler
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2000.
https://doi.org/10.1158/1538-7445.AM2015-2000
Published: 01 August 2015
View article titled, Abstract 2000: Proteomic features of histological compartments in colorectal carcinoma
Journal Articles

Abstract 924: GM-CSF induces CREB signaling pathways and modulates tobacco carcinogen-induced pancreatic tumorigenesis

Jason Castellanos, Kumaraswamy Honnenahally, Chanjuan Shi, Nipun Merchant, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 924.
https://doi.org/10.1158/1538-7445.AM2015-924
Published: 01 August 2015
View article titled, Abstract 924: GM-CSF induces CREB signaling pathways and modulates tobacco carcinogen-induced pancreatic tumorigenesis
Journal Articles

Abstract A33: γH2AX: A molecular marker of DNA damage response in smoking-induced pancreatic ductal adenocarcinoma

Kumaraswamy Honnenahally, Chanjuan Shi, Xi Chen, Jason Castellanos, Nipun Merchant, Timothy Blackwell, Nagaraj Nagathihalli
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): A33.
https://doi.org/10.1158/1538-7445.PANCA2014-A33
Published: 30 June 2015
View article titled, Abstract A33: γH2AX: A molecular marker of DNA damage response in smoking-induced pancreatic ductal adenocarcinoma
Journal Articles

Abstract A57: Crosstalk between pancreatic stellate cells and tissue macrophages modify the tumor microenvironment in pancreatic cancer.

Chanjuan Shi, Rupesh Chaturvedi, Frank Revetta, Keith T. Wilson, Mary K. Washington, Anna L. Means
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): A57.
https://doi.org/10.1158/1538-7445.PANCA2012-A57
Published: 03 April 2014
View article titled, Abstract A57: Crosstalk between pancreatic stellate cells and tissue macrophages modify the tumor microenvironment in pancreatic cancer.
Journal Articles

Abstract B32: JAK2 inhibition blocks STAT3 signaling and enhances drug delivery and therapeutic response in pancreatic cancer.

Nagaraj Nagathihalli, Yugandhar Beesetty, Michelle Reyzer, Chanjuan Shi, Richard Caprioli, Nipun Merchant
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B32.
https://doi.org/10.1158/1538-7445.PANCA2012-B32
Published: 03 April 2014
View article titled, Abstract B32: JAK2 inhibition blocks STAT3 signaling and enhances drug delivery and therapeutic response in pancreatic cancer.
Journal Articles

Abstract 1141: MAb-PAM4 can differentiate between pancreatic ductal adenocarcinoma and chronic pancreatitis.

David V. Gold, Chanjuan Shi, Guy Newsome, David M. Goldenberg
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1141.
https://doi.org/10.1158/1538-7445.AM2013-1141
Published: 15 April 2013
View article titled, Abstract 1141: MAb-PAM4 can differentiate between pancreatic ductal adenocarcinoma and chronic pancreatitis.
Journal Articles

Abstract 4173: In vivo and in vitro propagation of Intraductal Papillay Mucinous Neoplasms

Hirohiko Kamiyama, Mihoko Kamiyama, Seung-Mo Hong, Collins Karikari, Ming-Tseh Lin, Margaret Griffith, Angela Young, Alexis Kirby, Michael Borges, Conrad Lubek, Masamichi Mizuma, Georg Feldman, Chanjuan Shi, Hong Liang, Michael Goggins, Anirban Maitra, Ralph Hruban, James Eshleman
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4173.
https://doi.org/10.1158/1538-7445.AM10-4173
Published: 15 April 2010
View article titled, Abstract 4173: <em>In vivo and in vitro propagation of Intraductal Papillay Mucinous Neoplasms</em>