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Chang Xin Shi
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Journal Articles

Abstract 5588: PD-1 blockade synergizes with IMiDs to enhance bispecific T cell engager immune responses to Vk*MYChCRBN multiple myeloma by preventing T cell exhaustion

Erin W. Meermeier, Seth J. Welsh, Meaghen Sharik, Megan T. Du, Chang-Xin Shi, Bryant Chau, Feng Wang, Matthew Wheeler, Natalie Bezman, Pavel Strop, P. Leif Bergsagel, Marta Chesi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5588.
https://doi.org/10.1158/1538-7445.AM2022-5588
Published: 15 June 2022
View article titled, Abstract 5588: PD-1 blockade synergizes with IMiDs to enhance bispecific T cell engager immune responses to Vk*MYC<sup>hCRBN</sup> multiple myeloma by preventing T cell exhaustion
Journal Articles

Loss of FAM46C Promotes Cell Survival in Myeloma

Yuan Xiao Zhu, Chang-Xin Shi, Laura A. Bruins, Patrick Jedlowski, Xuewei Wang, K. Martin Kortüm, Moulun Luo, Jonathan M. Ahmann, Esteban Braggio, A. Keith Stewart
Journal: Cancer Research
Cancer Res (2017) 77 (16): 4317–4327.
https://doi.org/10.1158/0008-5472.CAN-16-3011
Published: 14 August 2017
View article titled, Loss of <em>FAM46C</em> Promotes Cell Survival in Myeloma
Open the PDF for Loss of <em>FAM46C</em> Promotes Cell Survival in Myeloma in another window
Includes: Supplementary data
Journal Articles

Identification of Molecular Vulnerabilities in Human Multiple Myeloma Cells by RNA Interference Lethality Screening of the Druggable Genome

Rodger E. Tiedemann, Yuan Xao Zhu, Jessica Schmidt, Chang Xin Shi, Chris Sereduk, Hongwei Yin, Spyro Mousses, A. Keith Stewart
Journal: Cancer Research
Cancer Res (2012) 72 (3): 757–768.
https://doi.org/10.1158/0008-5472.CAN-11-2781
Published: 31 January 2012
View article titled, Identification of Molecular Vulnerabilities in Human Multiple Myeloma Cells by RNA Interference Lethality Screening of the Druggable Genome
Open the PDF for Identification of Molecular Vulnerabilities in Human Multiple Myeloma Cells by RNA Interference Lethality Screening of the Druggable Genome in another window
Includes: Supplementary data
Journal Articles

Abstract LB-128: Synthetic lethal RNAi screening identifies inhibition of Bcl-2 family members as sensitizers to 5-Azacytidine in myeloid cells

James Bogenberger, Chang-Xin Shi, Tanner Hagelstrom, Irma Gonzales, Ashish Choudhary, Roger Tiedemann, David Azorsa, Keith Stewart, Raoul Tibes
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-128.
https://doi.org/10.1158/1538-7445.AM10-LB-128
Published: 15 April 2010
View article titled, Abstract LB-128: Synthetic lethal RNAi screening identifies inhibition of Bcl-2 family members as sensitizers to 5-Azacytidine in myeloid cells
Journal Articles

SNS-032, a potent and selective CDK2, 7 and 9 inhibitor, demonstrates preclinical activity in human multiple myeloma

Suzanne Trudel, Michael Sebag, Zhi Hua Li, Chang-Xin Shi, P Bergsagel, Marta Chesi, Lori Hazlehurst, Constantine Mitsiades, Sagar Lonial, Rachael Hawtin, Judith Fox, Pietro Taverna, A Stewart, MMRC Validation Team
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4972.
Published: 01 May 2008
View article titled, SNS-032, a potent and selective CDK2, 7 and 9 inhibitor, demonstrates preclinical activity in human multiple myeloma