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Journal Articles

Abstract CT099: BRIGHT-2 final analysis: A phase III trial of bireociclib plus fulvestrant as second-line endocrine therapy for patients with advanced HR+/HER2-breast cancer

Free
Jiayu Wang, Qingyuan Zhang, Huiping Li, Zhongsheng Tong, Quchang Ouyang, Huihui Li, Yuee Teng, Biyun Wang, Tao Sun, Jingfen Wang, Wei Li, Zhaofeng Niu, Hongsheng Li, Chang Gong, Li Wang, Fei Liu, Xianghui Duan, Qiuli Wang, Binghe Xu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): CT099.
https://doi.org/10.1158/1538-7445.AM2025-CT099
Published: 25 April 2025
View articletitled, Abstract CT099: BRIGHT-2 final analysis: A phase III trial of bireociclib plus fulvestrant as second-line endocrine therapy for patients with advanced HR+/HER2-breast cancer
Journal Articles

Abstract PO1-28-04: PILHLE-001: neoadjuvant pyrotinib combined with chemotherapy in HR-positive, HER2-low (IHC 2+/FISH-negative) early breast cancer

Free
Chang Gong, Yuan Xia, Yingying Zhu, Yaping Yang, Wenqian Yang, Louis W.C. Chow, Li Ling, Yunjie Zeng, Jiajie Zhong, Ziliang Cheng, Jun Shen, Qun Lin, Yinduo Zeng, Qiang Liu, Erwei Song
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-28-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-28-04
Published: 02 May 2024
View articletitled, Abstract PO1-28-04: PILHLE-001: neoadjuvant pyrotinib combined with chemotherapy in HR-positive, HER2-low (IHC 2+/FISH-negative) early breast cancer
Journal Articles

Abstract PO2-17-03: Patient reported outcomes (PROs) and survival with toremifene versus aromatase inhibitors (AI) in patients with moderate/high-risk premenopausal hormone receptor (HR)-positive breast cancer: A real-world study

Free
Yaping Yang, Fengxia Gan, Wenqian Yang, Yuan Xia, Qiang Liu, Chang Gong
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-17-03.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-17-03
Published: 02 May 2024
View articletitled, Abstract PO2-17-03: Patient reported outcomes (PROs) and survival with toremifene versus aromatase inhibitors (AI) in patients with moderate/high-risk premenopausal hormone receptor (HR)-positive breast cancer: A real-world study
Journal Articles

Abstract 7180: Tumor growth modeling to support dose justification of Dato-DXd in hormone receptor positive, HER2 negative breast cancer (HR+HER2-BC) subjects

Free
Zoey Tang, Yu Jiang, Haitao Yang, David Dai, Chang Gong, Linda Irons, Yuzhuo Pan, Ying Hong, Shuang Liang, Song Ren, Alex Phipps, Diansong Zhou
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7180.
https://doi.org/10.1158/1538-7445.AM2024-7180
Published: 22 March 2024
View articletitled, Abstract 7180: Tumor growth modeling to support dose justification of Dato-DXd in hormone receptor positive, HER2 negative breast cancer (HR+HER2-BC) subjects
Journal Articles

Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis

Free
Jharna Datta, Huban Kutay, Mohd W. Nasser, Gerard J. Nuovo, Bo Wang, Sarmila Majumder, Chang-Gong Liu, Stefano Volinia, Carlo M. Croce, Thomas D. Schmittgen, Kalpana Ghoshal, Samson T. Jacob
Journal: Cancer Research
Cancer Res (2023) 83 (24): 4181.
https://doi.org/10.1158/0008-5472.CAN-23-2365
Published: 15 December 2023
View articletitled, Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis
Open the PDF for Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis in another window
Journal Articles

Abstract P4-02-07: A large real-world study of circulating tumor DNA in early breast cancer patients

Free
Qiang Liu, Mengzi Wu, Shunying Li, Yudong Li, Liang Jin, Qianfeng Shi, Yu Zhang, Chang Gong
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-02-07.
https://doi.org/10.1158/1538-7445.SABCS22-P4-02-07
Published: 01 March 2023
View articletitled, Abstract P4-02-07: A large real-world study of circulating tumor DNA in early breast cancer patients
Journal Articles

Abstract PS18-21: Pulsed electric field exposure (PEFE) applied in breast cancer: A potential normothermic clinical cancer therapy

Free
Tracey Martin, Zhe Zhao, Chang Gong, Shuo Cai, Fiona Ruge, Philippa Young, Robert E Mansel, Johannes Benedikt, Wen G Jiang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS18-21.
https://doi.org/10.1158/1538-7445.SABCS20-PS18-21
Published: 15 February 2021
View articletitled, Abstract PS18-21: Pulsed electric field exposure (PEFE) applied in breast cancer: A potential normothermic clinical cancer therapy
Journal Articles

Abstract P1-20-26: Management of breast fibromatosis: Is further surgical resection treatment necessary after ultrasound-guided vacuum-assisted biopsy?

Free
Jingsi Mei, Yue Hu, Chang Gong
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P1-20-26.
https://doi.org/10.1158/1538-7445.SABCS19-P1-20-26
Published: 15 February 2020
View articletitled, Abstract P1-20-26: Management of breast fibromatosis: Is further surgical resection treatment necessary after ultrasound-guided vacuum-assisted biopsy?
Journal Articles

Abstract LB-307: Autophagy-associated circRNA AUACA1 mediates the proliferation of breast cancer cells via a miR-1275/ATG7/autophagic flux axis

Free
Gehao Liang, Yun Ling, Zihao Liu, Maryam Mehrpour, Ahmed Hamai, Zhenluan Tian, Luyuan Tan, Wenjing Zhong, Wanyi Lin, Patrice Codogno, Erwei Song, Chang Gong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-307.
https://doi.org/10.1158/1538-7445.AM2019-LB-307
Published: 01 July 2019
View articletitled, Abstract LB-307: Autophagy-associated circRNA AUACA1 mediates the proliferation of breast cancer cells via a miR-1275/ATG7/autophagic flux axis
Journal Articles

Abstract LB-391: Hsa_circ_001783 regulates breast cancer progression via sponging miR-200c

Free
Zihao Liu#, You Zhou#, Gehao Liang, Yun Ling, Luyuan Tan, Yan Wang, Wenjing Zhong, Chang Gong*
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-391.
https://doi.org/10.1158/1538-7445.AM2018-LB-391
Published: 01 July 2018
View articletitled, Abstract LB-391: Hsa_circ_001783 regulates breast cancer progression via sponging miR-200c
Journal Articles

Abstract 975: A multiscale computational model for spatio-temporal tumor immune response

Free
Chang Gong, Oleg Milberg, Bing Wang, Paolo Vicini, Rajesh Narwal, Lorin Roskos, Aleksander S. Popel
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 975.
https://doi.org/10.1158/1538-7445.AM2017-975
Published: 01 July 2017
View articletitled, Abstract 975: A multiscale computational model for spatio-temporal tumor immune response
Journal Articles

Abstract 4531: Systems pharmacology to predict cellular biomarkers and optimize mono- and combination-therapy regimens: Focusing on immune checkpoint targets PD-1, PD-L1 and CTLA-4

Free
Oleg Milberg, Chang Gong, Bing Wang, Paolo Vicini, Rajesh Narwal, Lorin Roskos, Aleksander Popel
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4531.
https://doi.org/10.1158/1538-7445.AM2017-4531
Published: 01 July 2017
View articletitled, Abstract 4531: Systems pharmacology to predict cellular biomarkers and optimize mono- and combination-therapy regimens: Focusing on immune checkpoint targets PD-1, PD-L1 and CTLA-4
Journal Articles

Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy

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Xiaohong Wang, Jonathan E. Schoenhals, Ailin Li, David R. Valdecanas, Huiping Ye, Fenglin Zang, Chad Tang, Ming Tang, Chang-Gong Liu, Xiuping Liu, Sunil Krishnan, James P. Allison, Padmanee Sharma, Patrick Hwu, Ritsuko Komaki, Willem W. Overwijk, Daniel R. Gomez, Joe Y. Chang, Stephen M. Hahn, Maria Angelica Cortez, James W. Welsh
Journal: Cancer Research
Cancer Res (2017) 77 (4): 839–850.
https://doi.org/10.1158/0008-5472.CAN-15-3142
Published: 14 February 2017
View articletitled, Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy
Open the PDF for Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract LB-139: Prognostic value of a BCSC-associated microRNA signature in hormone receptor-positive her2-negative breast cancer

Free
Chang Gong, Weige Tan, Kai Chen, Na You, Shan Zhu, Wei Luo, Xinhua Xie, Yunjie Zeng, Nengtai Ouyang, Zhihua Li, Mushen Zeng, ShiMei Zhuang, Wan-Yee Lau, Qiang Liu, Fengxi Su, Xueqin Wang, Erwei Song
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-139.
https://doi.org/10.1158/1538-7445.AM2016-LB-139
Published: 15 July 2016
View articletitled, Abstract LB-139: Prognostic value of a BCSC-associated microRNA signature in hormone receptor-positive her2-negative breast cancer
Journal Articles

FOXP3 Controls an miR-146/NF-κB Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells

Free
Runhua Liu, Cong Liu, Dongquan Chen, Wei-Hsiung Yang, Xiuping Liu, Chang-Gong Liu, Courtney M. Dugas, Fei Tang, Pan Zheng, Yang Liu, Lizhong Wang
Journal: Cancer Research
Cancer Res (2015) 75 (8): 1703–1713.
https://doi.org/10.1158/0008-5472.CAN-14-2108
Published: 14 April 2015
View articletitled, FOXP3 Controls an miR-146/NF-κB Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells
Open the PDF for FOXP3 Controls an miR-146/NF-κB Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

FOXP3–miR-146–NF-κB Axis and Therapy for Precancerous Lesions in Prostate

Free
Runhua Liu, Bin Yi, Shi Wei, Wei-Hsiung Yang, Karen M. Hart, Priyanka Chauhan, Wei Zhang, Xicheng Mao, Xiuping Liu, Chang-Gong Liu, Lizhong Wang
Journal: Cancer Research
Cancer Res (2015) 75 (8): 1714–1724.
https://doi.org/10.1158/0008-5472.CAN-14-2109
Published: 14 April 2015
View articletitled, FOXP3–miR-146–NF-κB Axis and Therapy for Precancerous Lesions in Prostate
Open the PDF for FOXP3–miR-146–NF-κB Axis and Therapy for Precancerous Lesions in Prostate in another window
Includes: Supplementary data
Journal Articles

miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors

Free
Chang Gong, Yan Nie, Shaohua Qu, Jian-You Liao, Xiuying Cui, Herui Yao, Yunjie Zeng, Fengxi Su, Erwei Song, Qiang Liu
Journal: Cancer Research
Cancer Res (2014) 74 (16): 4341–4352.
https://doi.org/10.1158/0008-5472.CAN-14-0125
Published: 13 August 2014
View articletitled, miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors
Open the PDF for miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors in another window
Includes: Supplementary data
Journal Articles

Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem–like Cell Traits in Breast Cancer

Free
Man-Li Luo, Chang Gong, Chun-Hau Chen, Daniel Y. Lee, Hai Hu, Pengyu Huang, Yandan Yao, Wenjun Guo, Ferenc Reinhardt, Gerburg Wulf, Judy Lieberman, Xiao Zhen Zhou, Erwei Song, Kun Ping Lu
Journal: Cancer Research
Cancer Res (2014) 74 (13): 3603–3616.
https://doi.org/10.1158/0008-5472.CAN-13-2785
Published: 30 June 2014
View articletitled, Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem–like Cell Traits in Breast Cancer
Open the PDF for Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem–like Cell Traits in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2157: Targeting the Maternal Embryonic Leucin zipper Kinase (MELK) in gastric cancers.

Free
Julie G. Izzo, Kevin N. Dalby, Han Liang, Hui Yao, Brian P. James, Saira Ahmed, Xiuping Liu, Chang-Gong Liu, Yon Hui Kim, Garth Powis
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2157.
https://doi.org/10.1158/1538-7445.AM2013-2157
Published: 15 April 2013
View articletitled, Abstract 2157: Targeting the Maternal Embryonic Leucin zipper Kinase (MELK) in gastric cancers.
Journal Articles

Abstract LB-43: MiR-147 is a novel tumor suppressor that reverses EMT and native resistance to EGFR inhibitors by inactivating Akt and activating Stat3.

Free
Chang Gong Lee, Michael Gruidl, Cindy R. Timmee, Susan McCarthy, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-43.
https://doi.org/10.1158/1538-7445.AM2013-LB-43
Published: 15 April 2013
View articletitled, Abstract LB-43: MiR-147 is a novel tumor suppressor that reverses EMT and native resistance to EGFR inhibitors by inactivating Akt and activating Stat3.