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Journal Articles

Abstract 5217: Genome instability in renal tumors

Hanbyul Cho, Ginny X. Li, Rahul Mannan, Noshad Hosseini, Yi Hsiao, Yuping Zhang, Aniket Dagar, Chandan Kumar-Sinha, Marcin P. Cieslik, Saravana M. Dhanasekaran, Alexey I. Nesvizhskii, Arul M. Chinnaiyan, Clinical Proteomic Tumor Analysis Consortium
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5217.
https://doi.org/10.1158/1538-7445.AM2024-5217
Published: 22 March 2024
View article titled, Abstract 5217: Genome instability in renal tumors
Journal Articles

Abstract 3127: Comprehensive proteogenomic characterization of rare kidney tumors

Ginny Xiaohe Li, Yi Hsiao, Lijun Chen, Rahul Mannan, Yuping Zhang, Francesca Petralia, Hanbyul Cho, Noshad Hosseini, Anna Calinawan, Yize Li, Shankara Anand, Aniket Dagar, Yifat Geffen, Felipe V. Leprevost, Anne Le, Sean Ponce, Michael Schnaubelt, Nataly Naser Al Deen, Wagma Caravan, Andrew Houston, Chandan Kumar-Sinha, Xiaoming Wang, Seema Chugh, Gilbert S. Omenn, Daniel W. Chan, Christopher Ricketts, Rohit Mehra, Arul Chinnaiyan, Li Ding, Marcin Cieslik, Hui Zhang, Saravana M. Dhanasekaran, Alexey I. Nesvizhskii
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3127.
https://doi.org/10.1158/1538-7445.AM2023-3127
Published: 04 April 2023
View article titled, Abstract 3127: Comprehensive proteogenomic characterization of rare kidney tumors
Journal Articles

Abstract 5719: Clinical response to the PDGFRα inhibitor avapritinib in high-grade glioma patients

Lisa Mayr, Maria Trissal, Kallen Schwark, Jenna Labelle, Andrew Groves, Julia Furtner-Srajer, Jeffrey Supko, Liesa Weiler-Wichtl, Olivia Hack, Jacob Rozowsky, Joana G. Marques, Eshini Pandatharatna, Ulrike Leiss, Verena Rosenmayr, Frank Dubois, Noah F. Greenwald, Sibylle Madlener, Armin S. Guntner, Hana Pálová, Natalia Stepien, Daniela Lötsch-Gojo, Christian Dorfer, Karin Dieckmann, Andreas Peyrl, Amedeo A. Azizi, Alicia Baumgartner, Ondřej Slabý, Petra Pokorná, Pratiti Bandopadhayay, Rameen Beroukhim, Keith Ligon, Christof Kramm, Annika Bronsema, Simon Bailey, Ana Guerreiro Stücklin, Sabine Mueller, David T. Jones, Natalie Jäger, Jaroslav Štěrba, Leonhard Müllauer, Christine Haberler, Chandan Kumar-Sinha, Arul Chinnaiyan, Rajen Mody, Mary Skrypek, Nina Martinez, Daniel C. Bowers, Carl Koschmann, Johannes Gojo, Mariella Filbin
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5719.
https://doi.org/10.1158/1538-7445.AM2023-5719
Published: 04 April 2023
View article titled, Abstract 5719: Clinical response to the PDGFRα inhibitor avapritinib in high-grade glioma patients
Journal Articles

Abstract 2578: An essential role for Argonaute 2 in HRAS and NRAS driven oncogenesis

Ronald F. Siebenaler, Jessica Waninger, Sunita Shankar, Seema Chugh, Shih-Chun Chu, Jean Tien, Vijaya L. Dommeti, Malay Mody, Anudeeta Gautam, Carson Kenum, Chandan Kumar-Sinha, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2578.
https://doi.org/10.1158/1538-7445.AM2020-2578
Published: 15 August 2020
View article titled, Abstract 2578: An essential role for <em>Argonaute 2</em> in <em>HRAS</em> and <em>NRAS</em> driven oncogenesis
Journal Articles

Abstract 2577: AGO2 interaction limits wild type RAS activation yet essential for disease progression in oncogenic KRAS driven cancers

Sunita Shankar, Jean Ching-Yi Tien, Ronald F. Siebenaler, Seema Chugh, Vijaya L. Dommeti, Sylvia Zelenka-Wang, Jessica Waninger, Kristin M. Juckette, Xiao-Ming Wang, Sanjana Eyunni, Andrew Goodrum, Yuping Zhang, Ingrid J. Apel, Javed Siddiqui, Xuhong Cao, Jiaqi Shi, Sethuramsundaram Pitchiaya, Chandan Kumar-Sinha, Howard C. Crawford, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2577.
https://doi.org/10.1158/1538-7445.AM2020-2577
Published: 15 August 2020
View article titled, Abstract 2577: AGO2 interaction limits wild type RAS activation yet essential for disease progression in oncogenic KRAS driven cancers
Journal Articles

Abstract 4420: Polytect, a robust algorithm to detect somatic mutations in polymorphic MHC/HLA genes

Michael Brodie Mumphrey, Abhijit Parolia, Chandan Kumar-Sinha, Marcin Cieslik
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4420.
https://doi.org/10.1158/1538-7445.AM2020-4420
Published: 15 August 2020
View article titled, Abstract 4420: Polytect, a robust algorithm to detect somatic mutations in polymorphic MHC/HLA genes
Journal Articles

Abstract 957: An essential role for Argonaute 2 in mouse models of KRAS-driven cancers

Sunita Shankar, Jean Ching-Yi Tien, Ronald F. Siebenaler, Vijaya L. Dommeti, Sylvia Zelenka-Wang, Jessica Waninger, Kristin M. Juckette, Alice Xu, Xiao-Ming Wang, Seema Chugh, Malay Mody, Sanjana Eyunni, Andrew Goodrum, Grace Tsaloff, Yuping Zhang, Ingrid J. Apel, Javed Siddiqui, Richard D. Smith, Heather A. Carlson, John Tesmer, Xuhong Cao, Jiaqi Shi, Chandan Kumar-Sinha, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 957.
https://doi.org/10.1158/1538-7445.AM2019-957
Published: 01 July 2019
View article titled, Abstract 957: An essential role for <em>Argonaute 2</em> in mouse models of <em>KRAS-</em>driven cancers
Journal Articles

Abstract 956: An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development

Ronald F. Siebenaler, Sunita Shankar, Jean C. Tien, Vijaya L. Dommeti, Sylvia Zelenka-Wang, Seema Chugh, Ingrid J. Apel, Malay Mody, Anudeeta Gautam, Chandan Kumar-Sinha, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 956.
https://doi.org/10.1158/1538-7445.AM2019-956
Published: 01 July 2019
View article titled, Abstract 956: An essential role for <em>Argonaute 2</em> in EGFR-KRAS signaling in pancreatic cancer development
Journal Articles

Abstract 3020: An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development

Sunita Shankar, Jean Tien, Ronald F. Siebenaler, Vijaya L. Dommeti, Sylvia Zelenka-Wang, Kristin M. Juckette, Alice Xu, Malay Mody, Andrew Goodrum, Grace Tsaloff, Ingrid J. Apel, Lisha Wang, Javed Siddiqui, Jiaqi Shi, Chandan Kumar-Sinha, Arul Chinnaiyan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3020.
https://doi.org/10.1158/1538-7445.AM2018-3020
Published: 01 July 2018
View article titled, Abstract 3020: An essential role for <em>Argonaute 2</em> in EGFR-KRAS signaling in pancreatic cancer development
Journal Articles

Abstract 4370: Regulation of AGO2-KRAS interaction through epidermal growth factor receptor

Ronald F. Siebenaler, Sunita Shankar, Jean C. Tien, Vijaya L. Dommeti, Malay Mody, Chandan Kumar-Sinha, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4370.
https://doi.org/10.1158/1538-7445.AM2018-4370
Published: 01 July 2018
View article titled, Abstract 4370: Regulation of AGO2-KRAS interaction through epidermal growth factor receptor
Journal Articles

Poor Prognosis Indicated by Venous Circulating Tumor Cell Clusters in Early-Stage Lung Cancers

Vasudha Murlidhar, Rishindra M. Reddy, Shamileh Fouladdel, Lili Zhao, Martin K. Ishikawa, Svetlana Grabauskiene, Zhuo Zhang, Jules Lin, Andrew C. Chang, Philip Carrott, William R. Lynch, Mark B. Orringer, Chandan Kumar-Sinha, Nallasivam Palanisamy, David G. Beer, Max S. Wicha, Nithya Ramnath, Ebrahim Azizi, Sunitha Nagrath
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (18): 5194–5206.
https://doi.org/10.1158/0008-5472.CAN-16-2072
Published: 14 September 2017
View article titled, Poor Prognosis Indicated by Venous Circulating Tumor Cell Clusters in Early-Stage Lung Cancers
Open the PDF for Poor Prognosis Indicated by Venous Circulating Tumor Cell Clusters in Early-Stage Lung Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 3029: An in vivo role for Argonaute 2 in KRAS driven pancreatic cancer

Sunita Shankar, Jean Tien, Vijaya L. Dommeti, Sylvia Zelenka-Wang, Ingrid A. Apel, Jiaqi Shi, Chandan Kumar-Sinha, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3029.
https://doi.org/10.1158/1538-7445.AM2017-3029
Published: 01 July 2017
View article titled, Abstract 3029: An in vivo role for Argonaute 2 in KRAS driven pancreatic cancer
Journal Articles

Abstract LB-008: KRAS engages AGO2 to enhance cellular transformation

Sunita Shankar, Sethuramasundaram Pitchiaya, Rohit Malik, Vishal Kothari, Yasuyuki Hosono, Anastasia K. Yocum, Harika Gundlapalli, Yasmine White, Ari Firestone, Xuhong Cao, Saravana M. Dhanasekaran, Jeanne Stuckey, Gideon Bollag, Kevin Shannon, Nils Walter, Chandan Kumar-Sinha, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-008.
https://doi.org/10.1158/1538-7445.AM2016-LB-008
Published: 15 July 2016
View article titled, Abstract LB-008: KRAS engages AGO2 to enhance cellular transformation
Journal Articles

ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms

Phillip L. Palmbos, Lidong Wang, Huibin Yang, Yin Wang, Jacob Leflein, McKenzie L. Ahmet, John E. Wilkinson, Chandan Kumar-Sinha, Gina M. Ney, Scott A. Tomlins, Stephanie Daignault, Lakshmi. P. Kunju, Xue-Ru Wu, Yair Lotan, Monica Liebert, Mats E. Ljungman, Diane M. Simeone
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (23): 5155–5166.
https://doi.org/10.1158/0008-5472.CAN-15-0603
Published: 30 November 2015
View article titled, ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms
Open the PDF for ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms in another window
Includes: Supplementary data
Journal Articles

Abstract LB-058: Novel interactions of the RAS oncoprotein

Sunita Shankar, Rohit Malik, Vishal Kothari, Yasuyuki Hosono, Sethuramasundaram Pitchiaya, Shanker Kalyana-Sundaram, Anastasia Yocum, June Escara-Wilke, Harika Gundlapalli, Krishnapriya Chinnaswamy, Matthew Shuler, Anton Poliakov, Xiaoju Wang, Vishalakshi Krishnan, Yasmine White, Ari Firestone, Xuhong Cao, Saravana M. Dhanasekaran, Jeanne Stuckey, Gideon Bollag, Kevin Shannon, Nils G. Walter, Chandan Kumar-Sinha, Arul Chinnaiyan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-058.
https://doi.org/10.1158/1538-7445.AM2015-LB-058
Published: 01 August 2015
View article titled, Abstract LB-058: Novel interactions of the RAS oncoprotein
Journal Articles

Abstract 1137: Bub1 is a key regulator of TGF-β signaling

Shyam Nyati, Katrina Schinske-Sebolt, Sethuramasundaram Pitchiaya, Katerina Chekhovskiy, Areeb Chator, Nauman Chaudhry, Joseph Dosch, Marcian E. Van Dort, Sooryanarayana Varambally, Chandan Kumar-Sinha, Mukesh K. Nyati, Dipankar Ray, Nils G. Walter, Hongtao Yu, Brian D. Ross, Alnawaz Rehemtulla
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1137.
https://doi.org/10.1158/1538-7445.AM2014-1137
Published: 01 October 2014
View article titled, Abstract 1137: Bub1 is a key regulator of TGF-β signaling
Journal Articles

Abstract A17: Inhibiting polo-like kinases for the treatment of pancreatic cancer: Targeting kinase outliers for personalized therapy.

Iris Wei, Vishal Kothari, Sunita Shankar, Shanker Kalyana-Sundaram, Catherine Grasso, Dan Robinson, Xuhong Cao, Diane Simeone, Arul Chinnaiyan, Chandan Kumar-Sinha
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): A17.
https://doi.org/10.1158/1538-7445.PANCA2012-A17
Published: 03 April 2014
View article titled, Abstract A17: Inhibiting polo-like kinases for the treatment of pancreatic cancer: Targeting kinase outliers for personalized therapy.
Journal Articles

Abstract 3136: Sample specific outlier kinase expression identified by RNA-Seq provide targets for precision therapy.

Chandan Kumar-Sinha, Vishal Kothari, Iris Wei, Sunita Shankar, Shanker Kalyana-Sundaram, Lidong Wang, Linda W. Ma, Pankaj Vats, Catherine Grasso, Dan Robinson, Yi-Mi Wu, Xuhong Cao, Diane M. Simeone, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3136.
https://doi.org/10.1158/1538-7445.AM2013-3136
Published: 15 April 2013
View article titled, Abstract 3136: Sample specific outlier kinase expression identified by RNA-Seq provide targets for precision therapy.
Journal Articles

Abstract 313: ATDC drives bladder cancer formation by promoting methylation of the PTEN promoter and inhibition of p53 function.

Phillip Palmbos, Lidong Wang, Huibin Yang, Taylor Detzler, Gina Ney, Justin Hart, Stephanie Daignault-Newton, L. Priya Kunju, Chandan Kumar-Sinha, Monica Liebert, Mats Ljungman, Diane Simeone
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 313.
https://doi.org/10.1158/1538-7445.AM2013-313
Published: 15 April 2013
View article titled, Abstract 313: ATDC drives bladder cancer formation by promoting methylation of the PTEN promoter and inhibition of p53 function.
Journal Articles

Abstract 5348: Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer.

Irfan A. Asangani, Bushra Ateeq, Qi Cao, Lois Dodson, Mithil Pandhi, Lakshmi P. Kunju, Rohit Mehra, Robert J. Lonigro, Javed Siddiqui, Nallasivam Palanisamy, Yi-Mi Wu, Xuhong Cao, Jung H. Kim, Mathew K. Iyer, Christopher A. Maher, Chandan Kumar-Sinha, Sooryanarayana Varambally, Arul M. Chinnaiyan, Meng Zhao, Zhaohui S. Qin
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5348.
https://doi.org/10.1158/1538-7445.AM2013-5348
Published: 15 April 2013
View article titled, Abstract 5348: Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer.