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Journal Articles

Abstract B046: Sensitizing the PDAC tumor microenvironment to immune checkpoint therapies: characterization of a PDAC 3D model to decipher immune infiltration

Thomas Bessede, Clara Freixinos, Jennifer Barrat, Véronique Garambois, Nadia Vie, Henri-Alexandre Michaud, Julien Faget, Nathalie Bonnefoy, Céline Gongora, Bruno Robert, Laurent Gros, Christel Larbouret
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): B046.
https://doi.org/10.1158/1538-7445.PANCREATIC24-B046
Published: 15 September 2024
View article titled, Abstract B046: Sensitizing the PDAC tumor microenvironment to immune checkpoint therapies: characterization of a PDAC 3D model to decipher immune infiltration
Journal Articles

Abstract B045: Sensitizing the PDAC tumor microenvironment to immune checkpoint therapies: characterization of a PDAC 3D model to decipher immune infiltration

Thomas Bessede, Clara Freixinos, Jennifer Barrat, Véronique Garambois, Nadia Vie, Henri-Alexandre Michaud, Julien Faget, Nathalie Bonnefoy, Céline Gongora, Bruno Robert, Laurent Gros, Christel Larbouret
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): B045.
https://doi.org/10.1158/1538-7445.PANCREATIC24-B045
Published: 15 September 2024
View article titled, Abstract B045: Sensitizing the PDAC tumor microenvironment to immune checkpoint therapies: characterization of a PDAC 3D model to decipher immune infiltration
Journal Articles

Abstract 5003: Efficacy of the STC-1010 a new allogenic cancer vaccine in different colorectal cancer models

George Alzeeb, Céline Gongora, Corentin Richard, Romain Boidot, Tanguy Fortin, Yan Wang, Alban Bessede, Benoit Pinteur, Lionel Chalus, Corinne Tortorelli, Paul Bravetti, François Ghiringhelli
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5003.
https://doi.org/10.1158/1538-7445.AM2024-5003
Published: 22 March 2024
View article titled, Abstract 5003: Efficacy of the STC-1010 a new allogenic cancer vaccine in different colorectal cancer models
Journal Articles

Abstract 5729: Imiqualines for pancreatic cancer: first-in-class potent and synergistic inhibitors of microtubule polymerisation

Kevin Bigot, Véronique Garambois, Nadia Vie, Marine Bruciamacchie, Pierre-Emmanuel Colombo, Diego Tosi, Cindy Patinote, Yann Maggipinto, Pierre-Antoine Bonnet, Céline Gongora, Carine Deleuze-Masquefa, Christel Larbouret
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5729.
https://doi.org/10.1158/1538-7445.AM2023-5729
Published: 04 April 2023
View article titled, Abstract 5729: Imiqualines for pancreatic cancer: first-in-class potent and synergistic inhibitors of microtubule polymerisation
Journal Articles

Abstract 1294: Platinum-based chemotherapy immunomodulatory effects and immunotherapy association in upper tract urothelial carcinomas

Alexandra Fauvre, Nadia Vie, Mathilde Robin, Clara Taffoni, Nadine Laguette, Julien Faget, Laurent Gros, Aurélie Garcin, Celine Gongora, Nadine Houede
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1294.
https://doi.org/10.1158/1538-7445.AM2022-1294
Published: 15 June 2022
View article titled, Abstract 1294: Platinum-based chemotherapy immunomodulatory effects and immunotherapy association in upper tract urothelial carcinomas
Journal Articles

Abstract 2051: Antitumor activity of a novel allogeneic colorectal cancer vaccine in C57BL/6 mice bearing MC38 anti-PD1 resistant colon carcinoma syngeneic model with TME

Céline Gongora, Elsa Kress, Claudine Vermot-Desroches, Lionel Chalus, Jeremy Forget, Benoît Pinteur, Paul Bravetti, Charles Dumontet, Antoîne Italiano
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2051.
https://doi.org/10.1158/1538-7445.AM2022-2051
Published: 15 June 2022
View article titled, Abstract 2051: Antitumor activity of a novel allogeneic colorectal cancer vaccine in C57BL/6 mice bearing MC38 anti-PD1 resistant colon carcinoma syngeneic model with TME
Journal Articles

Abstract 2589: Effect of folfirinox with an ATR inhibitor on pancreatic tumor cells and its microenvironment

Marine Bruciamacchie, Nadia Vie, Véronique Garambois, Diego Tosi, Pierre-Emmanuel Colombo, Céline Gongora, Christel Larbouret
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2589.
https://doi.org/10.1158/1538-7445.AM2022-2589
Published: 15 June 2022
View article titled, Abstract 2589: Effect of folfirinox with an ATR inhibitor on pancreatic tumor cells and its microenvironment
Journal Articles

Abstract P5-13-23: Pharmacokinetic determinants of palbociclib hematological toxicity

Fanny Leenhardt, Frédéric Fiteni, Ludovic Gauthier, Marie Alexandre, Séverine Guiu, Nelly Firmin, Stéphane Pouderoux, Chloé Gautier, Gerald Lossaint, Alexandre Payen, Celine Gongora, Litaty Mbatchi, Alexandre Evrard, William Jacot
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-13-23.
https://doi.org/10.1158/1538-7445.SABCS21-P5-13-23
Published: 15 February 2022
View article titled, Abstract P5-13-23: Pharmacokinetic determinants of palbociclib hematological toxicity
Journal Articles

Abstract PS5-16: Impact of drug-drug interaction on palbociclib serum levels: Interest of therapeutic drug monitoring

Fanny Leenhardt, Matthieu Gracia, Catherine Perrin, Claudia Muracciole-Bich, Bénédicte Marion, Celine Roques, Marie Alexandre, Nelly Firmin, Stephane Pouderoux, Litaty Mbatchi, Celine Gongora, William Jacot, Alexandre Evrard
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS5-16.
https://doi.org/10.1158/1538-7445.SABCS20-PS5-16
Published: 15 February 2021
View article titled, Abstract PS5-16: Impact of drug-drug interaction on palbociclib serum levels: Interest of therapeutic drug monitoring
Journal Articles

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer

Eve Combès, Augusto F. Andrade, Diego Tosi, Henri-Alexandre Michaud, Flavie Coquel, Veronique Garambois, Delphine Desigaud, Marta Jarlier, Arnaud Coquelle, Philippe Pasero, Nathalie Bonnefoy, Jerome Moreaux, Pierre Martineau, Maguy Del Rio, Roderick L. Beijersbergen, Nadia Vezzio-Vie, Celine Gongora
Journal: Cancer Research
Cancer Res (2019) 79 (11): 2933–2946.
https://doi.org/10.1158/0008-5472.CAN-18-2807
Published: 03 June 2019
View article titled, Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (<em>ATR</em>) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer
Open the PDF for Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (<em>ATR</em>) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2902: Targeting the tight junction protein claudin-1 in colorectal cancer

Sara Cherradi, Adeline Ayrolles-Torro, Nadia Vezzo-Vié, Eve Combes, Lucile Canterel-Thouennon, Fabien Gava, Valérie Lobjois, Bernard Ducommun, Celine Gongora, Maguy Del Rio
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2902.
https://doi.org/10.1158/1538-7445.AM2018-2902
Published: 01 July 2018
View article titled, Abstract 2902: Targeting the tight junction protein claudin-1 in colorectal cancer
Journal Articles

Abstract 1187: Synthetic lethality screening reveals ATR as responsible for oxaliplatin resistance in colorectal cancer cells

Eve Combes, Augusto Faria-Andrade, Diego Tosi, Pierre Martineau, Maguy Del Rio, Roderick Beijersbergen, Nadia Vie, Céline Gongora
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1187.
https://doi.org/10.1158/1538-7445.AM2017-1187
Published: 01 July 2017
View article titled, Abstract 1187: Synthetic lethality screening reveals ATR as responsible for oxaliplatin resistance in colorectal cancer cells
Journal Articles

Abstract 2378: A kinome analysis of the molecular pharmacodynamics of PT-112 in a human cancer cell line

Diego Tosi, Esther Perez-Gracia, Philippe Pourquier, Tyler D. Ames, Richard A. Wing, José Jimeno, Céline Gongora
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2378.
https://doi.org/10.1158/1538-7445.AM2017-2378
Published: 01 July 2017
View article titled, Abstract 2378: A kinome analysis of the molecular pharmacodynamics of PT-112 in a human cancer cell line
Journal Articles

Abstract 3681: Synergism analysis of dose matrices for combinations of BKM120 (a PI3K inhibitor), MEK162 (a MEK1/2 inhibitor) and chemotherapy in colorectal cancer (CRC) cell lines

Diego Tosi, Salima Atis, Caroline Mollevi, Pierre Martineau, Céline Gongora
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3681.
https://doi.org/10.1158/1538-7445.AM2014-3681
Published: 01 October 2014
View article titled, Abstract 3681: Synergism analysis of dose matrices for combinations of BKM120 (a PI3K inhibitor), MEK162 (a MEK1/2 inhibitor) and chemotherapy in colorectal cancer (CRC) cell lines
Journal Articles

Abstract 829: The novel camptothecin derivative and IAP inhibitor FL118 is an effective treatment for irinotecan-refractory colorectal cancer

David Westover, Xiang Ling, Xiaojun Liu, Hong Lam, Celine Gongora, Maguy Del Rio, Fengzhi Li
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 829.
https://doi.org/10.1158/1538-7445.AM2014-829
Published: 01 October 2014
View article titled, Abstract 829: The novel camptothecin derivative and IAP inhibitor FL118 is an effective treatment for irinotecan-refractory colorectal cancer
Journal Articles

Targeting the p38 MAPK Pathway Inhibits Irinotecan Resistance in Colon Adenocarcinoma

Salomé Paillas, Florence Boissière, Fréderic Bibeau, Amélie Denouel, Caroline Mollevi, Annick Causse, Vincent Denis, Nadia Vezzio-Vié, Laetitia Marzi, Cédric Cortijo, Imade Ait-Arsa, Nadav Askari, Philippe Pourquier, Pierre Martineau, Maguy Del Rio, Céline Gongora
Journal: Cancer Research
Cancer Res (2011) 71 (3): 1041–1049.
https://doi.org/10.1158/0008-5472.CAN-10-2726
Published: 01 February 2011
View article titled, Targeting the p38 MAPK Pathway Inhibits Irinotecan Resistance in Colon Adenocarcinoma
Open the PDF for Targeting the p38 MAPK Pathway Inhibits Irinotecan Resistance in Colon Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract #4730: The MAPK p38 implication in colon cancer chemoresistance is isoform specific

Céline Gongora, Salomé Paillas, Vincent Denis, Annick Causse, Nicole Bec, Christian Larroque, Nadia Vezzio, Nadav Askari, David Engelberg, Pierre Martineau, Maguy Del Rio
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4730.
Published: 01 May 2009
View article titled, Abstract #4730: The MAPK p38 implication in colon cancer chemoresistance is isoform specific
Journal Articles

Abstract #5428: Molecular profiling of metastatic colorectal cancer patient predicts FOLFIRI treatment response

Maguy Del Rio, Caroline Bascoul-Mollevi, Frédéric Bibeau, Nadia Vezzio, Céline Gongora, Patrick Chalbos, Florence Boissière-Michot, Catherine Fiess, Andrew Kramar, Eric Assenat, Marc Ychou, Pierre Martineau
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5428.
Published: 01 May 2009
View article titled, Abstract #5428: Molecular profiling of metastatic colorectal cancer patient predicts FOLFIRI treatment response
Journal Articles

Colon carcinoma cells resistant to chemotherapy overexpress interferon stimulated genes: role of p38 signaling pathway

Celine Gongora, Elodie Hatchi, Marielle Honorat, Nadia Vie, Virginie Copois, Pierre Martineau, Maguy Del Rio
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 300.
Published: 15 April 2006
View article titled, Colon carcinoma cells resistant to chemotherapy overexpress interferon stimulated genes: role of p38 signaling pathway