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Catherine J. Wu
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Journal Articles

Abstract 1387: Superoxide induces phosphorylation-mediated Mcl-1 stability to promote vresistance in hematologic malignancies

Free
Stephen J. Chong, Jolin X. Lai, Kartini Iskandar, Chuqi Wang, Yuhan Wang, Romaine Guieze, Deepika Raman, Rachel H. Lim, Catherine J. Wu, Wee Choo Chng, Alice M. Cheung, Charles T. Chuah, Matthew S. Davids, Shazib Pervaiz
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1387.
https://doi.org/10.1158/1538-7445.AM2025-1387
Published: 21 April 2025
View articletitled, Abstract 1387: Superoxide induces phosphorylation-mediated Mcl-1 stability to promote vresistance in hematologic malignancies
Journal Articles

Abstract C002: CKLF attracts CCR4-expressing CD4+ cells to foster immune repression and tumor aggressiveness in MYCN-driven neuroblastoma

Free
Xiaodan Qin, Hui Feng, Andrew Lam, Xu Zhang, Satyaki Sengupta, Bryan Iorgulescu, Sanjukta Das, Zhenwei Zhou, Tao Zuo, Grace Meara, Madison Rager, Alexander Floru, Hongru Ni, Chinyere Kemet, Divya Veerapaneni, Daniel Kashy, Liang Lin, Kenneth Lloyd, Lauren Kwok, Kaylee Smith, Raghavendar Nagaraju, Rob Meijers, Craig Ceol, Ching-Ti Liu, Sanda Alexandrescu, Catherine J. Wu, Derin Keskin, Rani George
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): C002.
https://doi.org/10.1158/1538-7445.TUMBODY-C002
Published: 17 November 2024
View articletitled, Abstract C002: CKLF attracts CCR4-expressing CD4+ cells to foster immune repression and tumor aggressiveness in MYCN-driven neuroblastoma
Journal Articles

Abstract 7474: T-cell responses across heart, blood, and tumor in patients with immune checkpoint inhibitor-related myocarditis (irMyocarditis)

Free
Steven Blum, Daniel A. Zlotoff, Neal P. Smith, Isabela J. Kernin, Swetha Ramesh, Giacomo Oliveira, Leyre Zubiri, Joshua Caplin, Nandini Samanta, Sidney Martin, Mike Wang, Alice Tirard, Pritha Sen, Yuhui Song, Katherine Xu, Jaimie L. Barth, Kamil Slowikowski, Mazen Nasrallah, Jessica Tantivit, Kasidet Manakongtreecheep, Benjamin Y. Arnold, John McGuire, Alexander B. Afeyan, Christopher J. Pinto, Daniel McLoughlin, Monica Jackson, PuiYee Chan, Aleigha Lawless, William A. Michaud, Tatyana Sharova, Linda T. Nieman, Justin F. Gainor, Dejan Juric, Mari Mino-Kenudsen, Ryan J. Sullivn, Genevieve M. Boland, James R. Stone, Catherine J. Wu, Molly F. Thomas, Tomas G. Neilan, Kerry L. Reynolds, Alexandra-Chloé Villani
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7474.
https://doi.org/10.1158/1538-7445.AM2024-7474
Published: 22 March 2024
View articletitled, Abstract 7474: T-cell responses across heart, blood, and tumor in patients with immune checkpoint inhibitor-related myocarditis (irMyocarditis)
Journal Articles

Abstract 4096: Comparative molecular profiling of sporadic and Lynch syndrome MSI tumors: Unraveling insights for vaccine design

Free
Hagay Ladany, Mark Grossman, Julian Hess, Nicole Lu, Derin Keskin, Catherine J. Wu, Nir Hacohen, Richard Gallon, John Burn, Heather Hampel, Zsofia Stadler, Gad Getz, Yosef E. Maruvka, Steven Lipkin
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4096.
https://doi.org/10.1158/1538-7445.AM2024-4096
Published: 22 March 2024
View articletitled, Abstract 4096: Comparative molecular profiling of sporadic and Lynch syndrome MSI tumors: Unraveling insights for vaccine design
Journal Articles

The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma

Open Access
R. Taylor Durall, Julianna Huang, Luke Wojenski, Yeying Huang, Prafulla C. Gokhale, Brittaney A. Leeper, Joshua O. Nash, Pedro L. Ballester, Scott Davidson, Adam Shlien, Emmanuel Sotirakis, Fabien Bertaux, Vincent Dubus, Jia Luo, Catherine J. Wu, Derin B. Keskin, Kyle P. Eagen, Geoffrey I. Shapiro, Christopher A. French
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3846–3860.
https://doi.org/10.1158/0008-5472.CAN-23-2545
Published: 01 December 2023
View articletitled, The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma
Open the PDF for The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma in another window
Includes: Supplementary data
Journal Articles

Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer

Open Access
Francisco Hermida-Prado, Yingtian Xie, Shira Sherman, Zsuzsanna Nagy, Douglas Russo, Tara Akhshi, Zhengtao Chu, Avery Feit, Marco Campisi, Minyue Chen, Agostina Nardone, Cristina Guarducci, Klothilda Lim, Alba Font-Tello, Irene Lee, Juana García-Pedrero, Israel Cañadas, Judith Agudo, Ying Huang, Tal Sella, Qingchun Jin, Nabihah Tayob, Elizabeth A. Mittendorf, Sara M. Tolaney, Xintao Qiu, Henry Long, William F. Symmans, Jia-Ren Lin, Sandro Santagata, Isabelle Bedrosian, Denise A. Yardley, Ingrid A. Mayer, Edward T. Richardson, Giacomo Oliveira, Catherine J. Wu, Eugene F. Schuster, Mitch Dowsett, Alana L. Welm, David Barbie, Otto Metzger, Rinath Jeselsohn
Journal: Cancer Research
Cancer Res (2023) 83 (19): 3284–3304.
https://doi.org/10.1158/0008-5472.CAN-23-1711
Published: 02 October 2023
View articletitled, Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer
Open the PDF for Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract A013: Tumor-specific immunity generated by a personalized neoantigen vaccination incorporating locally delivered ipilimumab in renal cell carcinoma

Free
David A. Braun, Derin B. Keskin, Sachet A. Shukla, Bradley A. McGregor, Nicholas R. Schindler, Eryn Blass, Susan Klaeger, Lucas Pomerance, Siranush Sarkizova, Shuqiang Li, Jackson Southard, Giorgia Moranzoni, Christina B. Pedersen, Yiwen Liu, Steven L. Chang, Michelle S. Hirsch, Nicole R. LeBoeuf, Matthew Mossanen, Vipheaviny Chea, Isabel Carulli, Oriol Olive, Ambica Mehndiratta, Haley Greenslade, Giacomo Oliveira, J. Bryan Iorgulescu, Sabina Signoretti, Jon C. Aster, Liudmila Elagina, Ignaty Leshchiner, Gad Getz, Maegan Harden, Stacey Gabriel, Lars R. Olsen, Donna S. Neuberg, Edward F. Fritsch, Nir Hacohen, Kenneth J. Livak, Steven Carr, Patrick A. Ott, Catherine J. Wu, Toni K. Choueiri
Journal: Cancer Research
Cancer Res (2023) 83 (16_Supplement): A013.
https://doi.org/10.1158/1538-7445.KIDNEY23-A013
Published: 15 August 2023
View articletitled, Abstract A013: Tumor-specific immunity generated by a personalized neoantigen vaccination incorporating locally delivered ipilimumab in renal cell carcinoma
Journal Articles

Abstract PR015: Tumor-specific immunity generated by a personalized neoantigen vaccination incorporating locally delivered ipilimumab in renal cell carcinoma

Free
David A. Braun, Derin B. Keskin, Sachet A. Shukla, Bradley A. McGregor, Nicholas R. Schindler, Eryn Blass, Susan Klaeger, Lucas Pomerance, Siranush Sarkizova, Shuqiang Li, Jackson Southard, Giorgia Moranzoni, Christina B. Pedersen, Yiwen Liu, Steven L. Chang, Michelle S. Hirsch, Nicole R. LeBoeuf, Matthew Mossanen, Vipheaviny Chea, Isabel Carulli, Oriol Olive, Ambica Mehndiratta, Haley Greenslade, Giacomo Oliveira, J. Bryan Iorgulescu, Sabina Signoretti, Jon C. Aster, Liudmila Elagina, Ignaty Leshchiner, Gad Getz, Maegan Harden, Stacey Gabriel, Lars R. Olsen, Donna S. Neuberg, Edward F. Fritsch, Nir Hacohen, Kenneth J. Livak, Steven Carr, Patrick A. Ott, Catherine J. Wu, Toni K. Choueiri
Journal: Cancer Research
Cancer Res (2023) 83 (16_Supplement): PR015.
https://doi.org/10.1158/1538-7445.KIDNEY23-PR015
Published: 15 August 2023
View articletitled, Abstract PR015: Tumor-specific immunity generated by a personalized neoantigen vaccination incorporating locally delivered ipilimumab in renal cell carcinoma
Journal Articles

Abstract B013: T cell clonotype expansion is common in advanced renal cell carcinoma but is not associated with altered response to PD-1 blockade

Free
Miya B. Hugaboom, Neil Ruthen, Opeyemi Jegede, Nicholas R. Schindler, Lena Wirth, Sasha Kyrysyuk, David F. McDermott, Elizabeth R. Plimack, Jeffrey A. Sosman, Naomi B. Haas, Michael E. Hurwitz, Hans J. Hammers, Sabina Signoretti, Michael B. Atkins, Catherine J. Wu, David A. Braun, Kelly Street
Journal: Cancer Research
Cancer Res (2023) 83 (16_Supplement): B013.
https://doi.org/10.1158/1538-7445.KIDNEY23-B013
Published: 15 August 2023
View articletitled, Abstract B013: T cell clonotype expansion is common in advanced renal cell carcinoma but is not associated with altered response to PD-1 blockade
Journal Articles

Abstract 886: Fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate on-target off-tumor side effects

Free
Yufei Wang, Alicia Buck, Gabriella Kastrunes, Rabia Abbas, Michael Lynch, Zhou Zhong, Song-My Hoang, Andras Miklosi, Kun Huang, Jae-Won Cho, Marion Grimaud, Cecile Razimbaud, Matthew Chang, Atef Fayed, Audrey Apollon, Nithyassree Murugan, Ze-Hua Li, Tran Thai, Luann Zerefa, Brandon Piel, Elena Ivanova, Amy Cameron, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Yasmin Nabil Laimon, Aseman Bagheri Sheshdeh, Sabina Signoretti, David A. Braun, Catherine J. Wu, Toni K. Choueiri, Jon Wee, Cloud P. Paweletz, Martin Hemberg, Aedin C. Culhane, David A. Barbie, Gordon J. Freeman, Wayne A. Marasco
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 886.
https://doi.org/10.1158/1538-7445.AM2023-886
Published: 04 April 2023
View articletitled, Abstract 886: Fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate on-target off-tumor side effects
Journal Articles

Mitochondrial DNA Mutations as Natural Barcodes for Lineage Tracing of Murine Tumor Models

Available to Purchase
Livius Penter, Elisa ten Hacken, Jackson Southard, Caleb A. Lareau, Leif S. Ludwig, Shuqiang Li, Donna S. Neuberg, Kenneth J. Livak, Catherine J. Wu
Journal: Cancer Research
Cancer Res (2023) 83 (5): 667–672.
https://doi.org/10.1158/0008-5472.CAN-22-0275
Published: 02 March 2023
View articletitled, Mitochondrial DNA Mutations as Natural Barcodes for Lineage Tracing of Murine Tumor Models
Open the PDF for Mitochondrial DNA Mutations as Natural Barcodes for Lineage Tracing of Murine Tumor Models in another window
Includes: Supplementary data
Journal Articles

Abstract 3575: Differential dynamics of response at single cell resolution between axi-cel and tisa-cel CAR-T therapy in refractory B-cell lymphomas

Free
Nicholas J. Haradhvala, Mark B. Leick, Katie Maurer, Satyen Gohil, Rebecca C. Larson, Estelle Yao, Matthew J. Frigault, Shuqiang Li, Kenneth J. Livak, Kahn Rhrissorrakrai, Filippo Utro, Chaya Levovitz, Raquel A. Jacobs, Kara Slowik, Brian P. Danysh, Laxmi Parida, Catherine J. Wu, Gad Getz, Marcela V. Maus
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3575.
https://doi.org/10.1158/1538-7445.AM2022-3575
Published: 15 June 2022
View articletitled, Abstract 3575: Differential dynamics of response at single cell resolution between axi-cel and tisa-cel CAR-T therapy in refractory B-cell lymphomas
Journal Articles

Abstract 4007: Evolutionary history of transformation from chronic lymphocytic leukemia to Richter’s syndrome

Free
Erin M. Parry, Ignaty Leshchiner, Romain Guièze, Connor Johnson, Eugen Tausch, Sameer Parikh, Camilla Lemvigh, Conor Messer, Daniel Rosebrock, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Matthew Davids, Raquel A. Jacobs, Kara Slowik, Julien Broseus, Shanye Yin, Shuqiang Li, Geoff Fell, Ziao Lin, Binyamin A. Knisbacher, Neil Ruthen, Dimitri Livitz, Christof Schneider, Jialin Ma, Julian Hess, Laura Z. Rassenti, Thomas J. Kipps, Nitin Jain, William Wierda, Florence Cymbalista, Neil E. Kay, Kenneth J. Livak, Brian P. Danysh, Chip Stewart, Donna Neuberg, Jennifer R. Brown, Laxmi Parida, Stephan Stilgenbauer, Gad Getz, Catherine J. Wu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4007.
https://doi.org/10.1158/1538-7445.AM2022-4007
Published: 15 June 2022
View articletitled, Abstract 4007: Evolutionary history of transformation from chronic lymphocytic leukemia to Richter’s syndrome
Journal Articles

Activation of Notch and Myc Signaling via B-cell–Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia

Available to Purchase
Anat Biran, Shanye Yin, Helene Kretzmer, Elisa ten Hacken, Salma Parvin, Fabienne Lucas, Mohamed Uduman, Catherine Gutierrez, Nathan Dangle, Leah Billington, Fara Faye Regis, Laura Z. Rassenti, Arman Mohammad, Gabriela Brunsting Hoffmann, Kristen Stevenson, Mei Zheng, Elizabeth Witten, Stacey M. Fernandes, Eugen Tausch, Clare Sun, Stephan Stilgenbauer, Jennifer R. Brown, Thomas J. Kipps, John C. Aster, Andreas Gnirke, Donna S. Neuberg, Anthony Letai, Lili Wang, Ruben D. Carrasco, Alexander Meissner, Catherine J. Wu
Journal: Cancer Research
Cancer Res (2021) 81 (24): 6117–6130.
https://doi.org/10.1158/0008-5472.CAN-21-1273
Published: 15 December 2021
View articletitled, Activation of Notch and Myc Signaling via B-cell–Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia
Open the PDF for Activation of Notch and Myc Signaling via B-cell–Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia in another window
Includes: Supplementary data
Journal Articles

60 Years Young: The Evolving Role of Allogeneic Hematopoietic Stem Cell Transplantation in Cancer Immunotherapy

Available to Purchase
Nicoletta Cieri, Katie Maurer, Catherine J. Wu
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4373–4384.
https://doi.org/10.1158/0008-5472.CAN-21-0301
Published: 01 September 2021
View articletitled, 60 Years Young: The Evolving Role of Allogeneic Hematopoietic Stem Cell Transplantation in Cancer Immunotherapy
Open the PDF for 60 Years Young: The Evolving Role of Allogeneic Hematopoietic Stem Cell Transplantation in Cancer Immunotherapy in another window
Journal Articles

Abstract 62: Development of dual-targeted fine-tuned immune restoring (DFIR) CAR T cell therapy for clear cell renal cell carcinoma (ccRCC)

Free
Yufei Wang, Alicia Buck, Marion Grimaud, Sreekumar Kodangattil, Cecile Razimbaud, Atef Fayed, Matthew Chang, Aedin Culhane, David A. Braun, Toni K. Choueiri, Catherine J. Wu, Kevin S. Wei, Leo L. Chan, Brandon P. Piel, Elena V. Ivanova, Cloud P. Paweletz, David A. Barbie, Rebecca Jennings, Miriam Ficial, Maura Aliezah Sticco-Ivins, Sabina Signoretti, Gordon J. Freeman, Quan K. Zhu, Wayne A. Marasco
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 62.
https://doi.org/10.1158/1538-7445.AM2021-62
Published: 01 July 2021
View articletitled, Abstract 62: Development of dual-targeted fine-tuned immune restoring (DFIR) CAR T cell therapy for clear cell renal cell carcinoma (ccRCC)
Journal Articles

Abstract PS4-25: Comprehensive genomic analysis reveals molecular correlates of response to immune checkpoint inhibitors (ICI) in metastatic triple-negative breast cancer (mTNBC)

Free
Romualdo Barroso-Sousa, Juliet Forman, Zachary T. Weber, Katherine Collier, Katrina Z. Kao, Edward T. Richardson, III, Tanya Keenan, Ofir Cohen, Michael P. Manos, Ryan C. Brennick, Patrick Ott, F. Steve Hodi, Deborah A. Dillon, Nancy U. Lin, Eliezer E. Van Allen, Scott Rodig, Eric P. Winer, Elizabeth A. Mittendorf, Catherine J. Wu, Daniel Stover, Nikhil Wagle, Sachet Shukla, Sara Tolaney
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS4-25.
https://doi.org/10.1158/1538-7445.SABCS20-PS4-25
Published: 15 February 2021
View articletitled, Abstract PS4-25: Comprehensive genomic analysis reveals molecular correlates of response to immune checkpoint inhibitors (ICI) in metastatic triple-negative breast cancer (mTNBC)
Journal Articles

Integrated Genomic Characterization of the Human Immunome in Cancer

Free
Yongsheng Li, Brandon Burgman, Daniel J. McGrail, Ming Sun, Dan Qi, Sachet A. Shukla, Erxi Wu, Anna Capasso, Shiaw-Yih Lin, Catherine J. Wu, S. Gail Eckhardt, Gordon B. Mills, Bo Li, Nidhi Sahni, S. Stephen Yi
Journal: Cancer Research
Cancer Res (2020) 80 (21): 4854–4867.
https://doi.org/10.1158/0008-5472.CAN-20-0384
Published: 03 November 2020
View articletitled, Integrated Genomic Characterization of the Human Immunome in Cancer
Open the PDF for Integrated Genomic Characterization of the Human Immunome in Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PO-097: High resolution analysis of clonal dynamics using lineage tracing and single cell transcriptomics

Free
Eric A. Brenner, Daylin Morgan, Aziz Al'Khafaji, Catherine Gutierrez, Catherine J. Wu, Amy Brock
Journal: Cancer Research
Cancer Res (2020) 80 (21_Supplement): PO-097.
https://doi.org/10.1158/1538-7445.TUMHET2020-PO-097
Published: 03 November 2020
View articletitled, Abstract PO-097: High resolution analysis of clonal dynamics using lineage tracing and single cell transcriptomics
Journal Articles

Abstract IA11: Detecting and targeting cellular heterogeneity of the lymphoid blood malignancies

Free
Catherine J. Wu
Journal: Cancer Research
Cancer Res (2020) 80 (21_Supplement): IA11.
https://doi.org/10.1158/1538-7445.TUMHET2020-IA11
Published: 03 November 2020
View articletitled, Abstract IA11: Detecting and targeting cellular heterogeneity of the lymphoid blood malignancies