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Caroline Jochems
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Journal Articles

Abstract PD9-02: Peripheral immune subsets and circulating tumor DNA (ctDNA) in patients (pts) with residual triple negative breast cancer (TNBC) treated with adjuvant immunotherapy and/or chemotherapy (chemo): The OXEL study

Filipa Lynce, Candace Mainor, Xue Geng, Greg Jones, Ilana Schlam, Hongkun Wang, Ute Feger, Renee Donahue, Nicole Toney, Caroline Jochems, Jeffrey Schlom, Christopher Gallagher, Rita Nanda, Deena Graham, Erica M Stringer-Reasor, Neelima Denduluri, Julie Collins, Asma A Dilawari, Ami Chitalia, Shruti Tiwari, Raquel Nunes, Rebecca Kaltman, Katia Khoury, Margaret Gatti-Mays, Sandra M Swain, Heather A. Parsons, Paula Pohlmann, Claudine Isaacs
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD9-02.
https://doi.org/10.1158/1538-7445.SABCS21-PD9-02
Published: 15 February 2022
View article titled, Abstract PD9-02: Peripheral immune subsets and circulating tumor DNA (ctDNA) in patients (pts) with residual triple negative breast cancer (TNBC) treated with adjuvant immunotherapy and/or chemotherapy (chemo): The OXEL study
Journal Articles

Abstract OT2-03-04: A trial of induction Talazoparib followed by a combination of Talazoparib and Avelumab in advanced breast cancer: The TALAVE study

Arielle L Heeke, Michael Pishvaian, Hongkun Wang, Adam Cohen, Jeffrey Schlom, Renee Donahue, Caroline Jochems, Margaret Gatti-Mays, Paula Pohlmann, Antoinette Tan, Claudine Isaacs, Filipa Lynce
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): OT2-03-04.
https://doi.org/10.1158/1538-7445.SABCS19-OT2-03-04
Published: 15 February 2020
View article titled, Abstract OT2-03-04: A trial of induction Talazoparib followed by a combination of Talazoparib and Avelumab in advanced breast cancer: The TALAVE study
Journal Articles

Abstract OT1-08-01: A phase Ib trial of sequential combinations of BN-brachyury, entinostat, ado-trastuzumab emtansine (T-DM1) and bintrafusp alfa (M7824) in advanced stage breast cancer (BrEAsT)

Margaret E Gatti-Mays, Claudia Palena, Sofia R Gameiro, Renee N Donahue, Caroline Jochems, Seth Steinberg, Stan Lipkowitz, Alexandra Zimmer, Deneise Francis, Julius Strauss, Houssein Abdul Sater, Lisa Cordes, Jason Redman, Fatima Karzai, Marijo Bilusic, Ravi A Madan, James L Gulley, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): OT1-08-01.
https://doi.org/10.1158/1538-7445.SABCS19-OT1-08-01
Published: 15 February 2020
View article titled, Abstract OT1-08-01: A phase Ib trial of sequential combinations of BN-brachyury, entinostat, ado-trastuzumab emtansine (T-DM1) and bintrafusp alfa (M7824) in advanced stage breast cancer (BrEAsT)
Journal Articles

Abstract 1406: Analysis of immune responses as a consequence of androgen deprivation therapy in patients with biochemical progression of prostate cancer

Caroline Jochems, Ravi A. Madan, Romaine I. Fernando, James L. Gulley, Kwong Y. Tsang, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1406.
https://doi.org/10.1158/1538-7445.AM2016-1406
Published: 15 July 2016
View article titled, Abstract 1406: Analysis of immune responses as a consequence of androgen deprivation therapy in patients with biochemical progression of prostate cancer
Journal Articles

Abstract 1403: Correlations between overall survival and patient regulatory T-cell levels at initiation of Folfiri therapy in colorectal cancer

Caroline Jochems, Vittore Cereda, Romaine I. Fernando, Jacob Richards, Italia Grenga, Patrizia Ferroni, Fiorella Guadagni, Jeffrey Schlom, Mario Roselli
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1403.
https://doi.org/10.1158/1538-7445.AM2016-1403
Published: 15 July 2016
View article titled, Abstract 1403: Correlations between overall survival and patient regulatory T-cell levels at initiation of Folfiri therapy in colorectal cancer
Journal Articles

Abstract 1316: Evaluation of immune cell subsets of cancer patients treated with a fully human IgG1 anti-PD-L1 MAb (MSB0010718C) capable of mediating ADCC of human tumor cells

Lauren M. Lepone, Renee N. Donahue, Benedetto Farsaci, Italia Grenga, Benjamin Boyerinas, Caroline Jochems, Kwong-Yok Tsang, Christopher R. Heery, Ravi A. Madan, Geraldine O'Sullivan Coyne, Harpreet Singh, James L. Gulley, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1316.
https://doi.org/10.1158/1538-7445.AM2015-1316
Published: 01 August 2015
View article titled, Abstract 1316: Evaluation of immune cell subsets of cancer patients treated with a fully human IgG1 anti-PD-L1 MAb (MSB0010718C) capable of mediating ADCC of human tumor cells
Journal Articles

Abstract 628: Pan-Bcl-2 inhibitor, GX15-070 (Obatoclax), decreases human T regulatory lymphocytes while preserving effector T Lymphocytes: A rationale for its use in combination immunotherapy

Peter S. Kim, Caroline Jochems, Italia Grenga, Renee N. Donahue, Kwong Y. Tsang, James L. Gulley, Jeffrey Schlom, Benedetto Farsaci
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 628.
https://doi.org/10.1158/1538-7445.AM2014-628
Published: 01 October 2014
View article titled, Abstract 628: Pan-Bcl-2 inhibitor, GX15-070 (Obatoclax), decreases human T regulatory lymphocytes while preserving effector T Lymphocytes: A rationale for its use in combination immunotherapy
Journal Articles

Abstract 2546: Analysis of immune cell subsets in a multidrug therapeutic regimen for patients with metastatic castration-resistant prostate cancer

Caroline Jochems, Benjamin Boyerinas, Ravi A. Madan, Diane J. Poole, Yang-Min Ning, William D. Figg, David J. Liewehr, Seth M. Steinberg, James L. Gulley, Kwong-Yok Tsang, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2546.
https://doi.org/10.1158/1538-7445.AM2014-2546
Published: 01 October 2014
View article titled, Abstract 2546: Analysis of immune cell subsets in a multidrug therapeutic regimen for patients with metastatic castration-resistant prostate cancer
Journal Articles

Abstract 2561: Yeast vector-encoding multiple MUC1 agonist epitopes (yeast-MUC1) can induce MUC1-specific T-cell immune responses

Kwong Y. Tsang, Benjamin Boyerinas, Caroline Jochems, Tim Rodell, Thomas King, Jeffey Schlom
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2561.
https://doi.org/10.1158/1538-7445.AM2014-2561
Published: 01 October 2014
View article titled, Abstract 2561: Yeast vector-encoding multiple MUC1 agonist epitopes (yeast-MUC1) can induce MUC1-specific T-cell immune responses
Journal Articles

Abstract 5012: A combination trial of vaccine plus ipilimumab in metastatic castration-resistant prostate cancer patients: Immune correlates

Geraldine O'Sullivan Coyne, Caroline Jochems, Christopher Heery, Harpreet Singh, Ira Surolia, Robin Riley, Ravi Madan, William Dahut, Seth Steinberg, James Gulley, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5012.
https://doi.org/10.1158/1538-7445.AM2014-5012
Published: 01 October 2014
View article titled, Abstract 5012: A combination trial of vaccine plus ipilimumab in metastatic castration-resistant prostate cancer patients: Immune correlates
Journal Articles

Abstract IA13: Phase I trial of targeted therapy with PSA-TRICOM vaccine (V) and ipilimumab (ipi) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).

James L. Gulley, Ravi A. Madan, Kwong Y. Tsang, Caroline Jochems, William L. Dahut, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): IA13.
https://doi.org/10.1158/1538-7445.TUMIMM2012-IA13
Published: 02 April 2014
View article titled, Abstract IA13: Phase I trial of targeted therapy with PSA-TRICOM vaccine (V) and ipilimumab (ipi) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC).
Journal Articles

Abstract 1260: Generation of human T cells directed against an agonist epitope of a transcription factor involved in epithelial to mesenchymal transition (EMT).

Jo A. Tucker, Diane J. Poole, Claudia Palena, Caroline Jochems, Jeffrey Schlom, Kwong Y. Tsang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1260.
https://doi.org/10.1158/1538-7445.AM2013-1260
Published: 15 April 2013
View article titled, Abstract 1260: Generation of human T cells directed against an agonist epitope of a transcription factor involved in epithelial to mesenchymal transition (EMT).
Journal Articles

Abstract 498: A combination trial of vaccine plus ipilimumab in patients with metastatic castration-resistant prostate cancer: immune correlates.

Caroline Jochems, Jo A. Tucker, Ravi A. Madan, William L. Dahut, James L. Gulley, Jeffrey Schlom, Kwong-Yok Tsang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 498.
https://doi.org/10.1158/1538-7445.AM2013-498
Published: 15 April 2013
View article titled, Abstract 498: A combination trial of vaccine plus ipilimumab in patients with metastatic castration-resistant prostate cancer: immune correlates.
Journal Articles

Abstract 5379: Combination treatment with Bevacizumab, Lenalidomide, Docetaxel and Prednisone (ART-P) does not impact the immune response in patients with metastatic castration-resistant prostate cancer

Caroline Jochems, Jo A. Tucker, Diane J. Poole, Melony Beatson, Marcia Mulquin, Ravi A. Madan, William D. Figg, William L. Dahut, James L. Gulley, Jeffrey Schlom, Kwong-Yok Tsang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5379.
https://doi.org/10.1158/1538-7445.AM2012-5379
Published: 15 April 2012
View article titled, Abstract 5379: Combination treatment with Bevacizumab, Lenalidomide, Docetaxel and Prednisone (ART-P) does not impact the immune response in patients with metastatic castration-resistant prostate cancer
Journal Articles

Abstract 5404: Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer

Jo A. Tucker, Ngar-Yee Huen, Alan LY Pang, Tin-Lap lee, Matteo Vergati, Chiara Intrivici, Vittore Cereda, Caroline Jochems, Wai-Yee Chan, Owen Rennert, James L. Gulley, Jeffrey Schlom, Kwong-Yok Tsang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5404.
https://doi.org/10.1158/1538-7445.AM2012-5404
Published: 15 April 2012
View article titled, Abstract 5404: Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer
Journal Articles

Abstract 5524: Generation of cellular immune responses to MUC1-C to target the portion of MUC1 that is most biologically relevant to the transformation process

Caroline Jochems, Diane J. Poole, Matteo Vergati, James L. Gulley, Jeffrey Schlom, Kwong Yok Tsang
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5524.
https://doi.org/10.1158/1538-7445.AM2011-5524
Published: 15 April 2011
View article titled, Abstract 5524: Generation of cellular immune responses to MUC1-C to target the portion of MUC1 that is most biologically relevant to the transformation process
Journal Articles

Abstract 758: Cancer vaccine immunotherapy employing Saccharomyces cerevisiae (yeast) as a vector can modulate the balance between CD4+ T cells and regulatory T cells (Tregs) and enhance the specific antitumor immune response

Matteo Vergati, Vittore Cereda, Chiara Intrivici, Ngar-Yee Huen, Maria Giovanna Di Bari, Caroline Jochems, James L. Gulley, David Apelian, Jeffrey Schlom, Kwong Y. Tsang
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 758.
https://doi.org/10.1158/1538-7445.AM2011-758
Published: 15 April 2011
View article titled, Abstract 758: Cancer vaccine immunotherapy employing Saccharomyces cerevisiae (yeast) as a vector can modulate the balance between CD4+ T cells and regulatory T cells (Tregs) and enhance the specific antitumor immune response