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Caroline Hoffmann
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Journal Articles

Abstract 2422: Fine-grained inflammatory cell segmentation in histopathology with deep learning

Free
Pierre-Antoine Bannier, Benjamin Adjadj, Sebastien Mandela, Guillaume Horent, Thomas Mathieu, Ulysse Marteau, Valentin Gaury, Laura Dumont, Aurore Lyon, Reda Belbahri, Benoit Schmauch, Kathryn Schutte, Lucie Gillet, Katharina Von Loga, Caroline Hoffmann
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2422.
https://doi.org/10.1158/1538-7445.AM2025-2422
Published: 21 April 2025
View articletitled, Abstract 2422: Fine-grained inflammatory cell segmentation in histopathology with deep learning
Journal Articles

Abstract 1072: MOSAIC Window: Spatial intra-tumoral heterogeneity characterization through large-scale spatial and single-nuclei multi-omics profiling

Free
The MOSAIC Consortium (Owkin, FR; Charite, DE; CHUV, CH; GR, FR; UKER, DE; UPMC, USA), Presenter: Caroline Hoffmann
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1072.
https://doi.org/10.1158/1538-7445.AM2025-1072
Published: 21 April 2025
View articletitled, Abstract 1072: MOSAIC Window: Spatial intra-tumoral heterogeneity characterization through large-scale spatial and single-nuclei multi-omics profiling
Journal Articles

Abstract 7395: Histology-based prognosis prediction using deep learning outperforms and is independent of the MGMT methylation status in patients with glioblastoma

Free
Lucas Fidon, Celine Thiriez, Alexandre Grimaldi, Omar Darwiche Domingues, Charles Maussion, Caroline Hoffmann
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7395.
https://doi.org/10.1158/1538-7445.AM2024-7395
Published: 22 March 2024
View articletitled, Abstract 7395: Histology-based prognosis prediction using deep learning outperforms and is independent of the MGMT methylation status in patients with glioblastoma
Journal Articles

Abstract 4603: Single-cell and spatial dissection of the effect of combined PD-L1 and TGFb blockade by bintrafusp alfa from the ICING window-of-opportunity trial in resectable locally advanced HNSCC patients

Free
Caroline Hoffmann, Jan-Timon Werle, Jocelyn Gal, Philemon Sirven, Jerzy Klijanienko, Jeremy Mesple, Benjamin Demaille, Wail Zeitouni, Olivier Choussy, Gregoire Marret, Nathalie Badois, Antoine Dubray-Vautrin, Gilles Dolivet, Lionnel Geoffrois, Maud Kamal, Ivan Bieche, Laure Monard, Clotilde Simon, Christophe Le Tourneau, Helene Salmon
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4603.
https://doi.org/10.1158/1538-7445.AM2024-4603
Published: 22 March 2024
View articletitled, Abstract 4603: Single-cell and spatial dissection of the effect of combined PD-L1 and TGFb blockade by bintrafusp alfa from the ICING window-of-opportunity trial in resectable locally advanced HNSCC patients
Journal Articles

Meta-Analysis of Human Cancer Single-Cell RNA-Seq Datasets Using the IMMUcan Database

Open Access
Jordi Camps, Floriane Noël, Robin Liechti, Lucile Massenet-Regad, Sidwell Rigade, Lou Götz, Caroline Hoffmann, Elise Amblard, Melissa Saichi, Mahmoud M. Ibrahim, Jack Pollard, Jasna Medvedovic, Helge G. Roider, Vassili Soumelis
Journal: Cancer Research
Cancer Res (2023) 83 (3): 363–373.
https://doi.org/10.1158/0008-5472.CAN-22-0074
Published: 03 February 2023
View articletitled, Meta-Analysis of Human Cancer Single-Cell RNA-Seq Datasets Using the IMMUcan Database
Open the PDF for Meta-Analysis of Human Cancer Single-Cell RNA-Seq Datasets Using the IMMUcan Database in another window
Includes: Supplementary data
Journal Articles

Abstract 1237: Randomized phase II trial of pre-operative afatinib in non-metastatic head and neck squamous cell carcinoma patients: Identification of predictive biomarkers of response

Free
Grégoire Marret, Maud Kamal, Jocelyn Gal, Stéphane Temam, Jerzy Klijianenko, Jean-Pierre Delord, Caroline Hoffmann, Gilles Dolivet, Olivier Malard, Jerôme Fayette, Olivier Capitain, Caroline Even, Sébastien Vergez, Lionel Geoffrois, Frédéric Rolland, Philippe Zrounba, Laurent Laccourreye, Joël Guigay, Nicolas Aide, Valérie Bénavent, Constance Lamy, Elodie Girard, Marta Jimenez, Ivan Bièche, Christophe Le Tourneau
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1237.
https://doi.org/10.1158/1538-7445.AM2022-1237
Published: 15 June 2022
View articletitled, Abstract 1237: Randomized phase II trial of pre-operative afatinib in non-metastatic head and neck squamous cell carcinoma patients: Identification of predictive biomarkers of response
Journal Articles

Abstract 5011: Meta-analysis of human cancer single cell RNAseq datasets using the fully integrated IMMUcan database

Free
Jordi Camps, Floriane Noel, Robin Liechti, Lou Goetz, Caroline Hoffmann, Lucile Massenet-Regad, Elise Amblard, Melissa Saichi, Mahmoud M. Ibrahim, Jack Pollard, Jasna Medvedovic, Helge G. Roider, Vassili Soumelis
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5011.
https://doi.org/10.1158/1538-7445.AM2022-5011
Published: 15 June 2022
View articletitled, Abstract 5011: Meta-analysis of human cancer single cell RNAseq datasets using the fully integrated IMMUcan database
Journal Articles

Abstract 2105: PD-L1 high ICOSL low Secretory dendritic cells infiltrate human solid tumors

Free
Caroline Hoffmann, Floriane Noël, Maximilien Grandclaudon, Lucile Massenet-Regad, Paula Michea, Philemon Sirven, Lilith Faucheux, Aurore Surun, Olivier Lantz, Mylene Bohec, Jian Ye, Weihua Guo, Juliette Rochefort, Jerzy Klijanienko, Sylvain Baulande, Charlotte Lecerf, Maud Kamal, Christophe Le Tourneau, Maude Guillot-Delost, Vassili Soumelis
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2105.
https://doi.org/10.1158/1538-7445.AM2022-2105
Published: 15 June 2022
View articletitled, Abstract 2105: PD-L1 high ICOSL low Secretory dendritic cells infiltrate human solid tumors
Journal Articles

Abstract 5001: Open-label, non-randomized, exploratory pre-operative window-of-opportunity trial to investigate the pharmacokinetics and pharmacodynamics of the smac mimetic Debio 1143 in patients with resectable squamous cell carcinoma of the head and neck

Free
Carlos Gomez-Roca, Caroline Even, Christophe Le Tourneau, Neus Basté Rotllan, Jean-Pierre Delord, Jerome Sarini, Sebastien Vergez, Stephane Teman, Caroline Hoffmann, Philippe Rochaix, Bruno Gavillet, Elisabeth Rouits, Franck Brichory, Dalit Rechavi-Robinson, Vincent Bize, Sebastien Del Rizzo, Daniela Purcea, Silvano Brienza, Claudio Zanna, Gregoire Vuagniaux, Sergio Szyldergemajn
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5001.
https://doi.org/10.1158/1538-7445.AM2019-5001
Published: 01 July 2019
View articletitled, Abstract 5001: Open-label, non-randomized, exploratory pre-operative window-of-opportunity trial to investigate the pharmacokinetics and pharmacodynamics of the smac mimetic Debio 1143 in patients with resectable squamous cell carcinoma of the head and neck
Journal Articles

Abstract 2600: Resistance biomarkers in patients with head and neck squamous cell carcinoma treated with cetuximab

Free
Maud Kamal, Olivia Leblanc, Sophie Vacher, Charlotte Lecerf, Emmanuelle Jeannot, Jerzy Klijanienko, Frederique Berger, Caroline Hoffmann, Valentin Calugaru, Nathalie Badois, Anne Chilles, Maria Lesnik, Samar Krhili, Thomas Jouffroy, Ivan Bieche, Christophe Le Tourneau
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2600.
https://doi.org/10.1158/1538-7445.AM2018-2600
Published: 01 July 2018
View articletitled, Abstract 2600: Resistance biomarkers in patients with head and neck squamous cell carcinoma treated with cetuximab
Journal Articles

Abstract 2714: Combination of monalizumab and durvalumab as a potent immunotherapy treatment for solid human cancers

Free
Caroline Soulas, Romain Remark, Vedran Brezar, Julie Lopez, Elodie Bonnet, Flavien Caraguel, Ana Lalanne, Caroline Hoffmann, Caroline Denis, Thomas Arnoux, Clarisse Caillet, Arnaud Dujardin, Guillaume Habif, Olivier Lantz, Cécile Bonnafous, Eric Vivier, Pascale Andre
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2714.
https://doi.org/10.1158/1538-7445.AM2018-2714
Published: 01 July 2018
View articletitled, Abstract 2714: Combination of monalizumab and durvalumab as a potent immunotherapy treatment for solid human cancers