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Journal Articles

Loss of Integrin-Linked Kinase Sensitizes Breast Cancer to SRC Inhibitors

Henry Beetham, Billie G.C. Griffith, Olga Murina, Alexander E.P. Loftus, David A. Parry, Carolin Temps, Jayne Culley, Morwenna Muir, Asier Unciti-Broceta, Andrew H. Sims, Adam Byron, Valerie G. Brunton
Journal: Cancer Research
Cancer Res (2022) 82 (4): 632–647.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-0373
Published: 17 December 2021
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Includes: Supplementary data
Journal Articles

A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability

Carolin Temps, Daniel Lietha, Emily R. Webb, Xue-Feng Li, John C. Dawson, Morwenna Muir, Kenneth G. Macleod, Teresa Valero, Alison F. Munro, Rafael Contreras-Montoya, Juan R. Luque-Ortega, Craig Fraser, Henry Beetham, Christina Schoenherr, Maria Lopalco, Mark J. Arends, Margaret C. Frame, Bin-Zhi Qian, Valerie G. Brunton, Neil O. Carragher, Asier Unciti-Broceta
Journal: Cancer Research
Cancer Res (2021) 81 (21): 5438–5450.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-0613
Published: 01 November 2021
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Includes: Supplementary data