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Carol Aghajanian
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Journal Articles

Abstract LB089: Effective in vivo treatment of endometrial tumor models with coexistent mutant PI3K and PTEN inactivation with a selective bi-steric mTORC1 kinase inhibitor

Hilla Solomon, Radha Mukherjee, Xiaoping Chen, HuiYong Zhao, Elisa de Stanchina, Britta Weigelt, Alison M. Schram, Carol Aghajanian, Mallika Singh, Jan Smith, Neal Rosen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB089.
DOI: https://doi.org/10.1158/1538-7445.AM2022-LB089
Published: 15 June 2022
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Journal Articles

Abstract 2553: Immune and malignant cell phenotypes of ovarian cancer are determined by distinct mutational processes

Ignacio Vázquez-García, Florian Uhlitz, Nicholas Ceglia, Jamie L. Lim, Michelle Wu, Neeman Mohibullah, Arvin Eric B. Ruiz, Kevin M. Boehm, Viktoria Bojilova, Christopher J. Fong, Tyler Funnell, Diljot Grewal, Eliyahu Havasov, Samantha Leung, Arfath Pasha, Druv M. Patel, Maryam Pourmaleki, Nicole Rusk, Hongyu Shi, Rami Vanguri, Marc J. Williams, Allen W. Zhang, Vance Broach, Dennis S. Chi, Arnaud Da Cruz Paula, Ginger J. Gardner, Sarah H. Kim, Matthew Lennon, Kara Long Roche, Yukio Sonoda, Oliver Zivanovic, Ritika Kundra, Agnes Viale, Yonina Bykov, Fatemeh N. Derakhshan, Luke Geneslaw, Ana Maroldi, Andrea Schietinger, Travis J. Hollmann, Samuel F. Bakhoum, Robert A. Soslow, Lora H. Ellenson, Nadeem Abu-Rustum, Carol Aghajanian, Claire F. Friedman, Andrew McPherson, Britta Weigelt, MSK SPECTRUM Consortium, Dmitriy Zamarin, Sohrab P. Shah
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2553.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2553
Published: 15 June 2022
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Journal Articles

Mutant FOXL2C134W Hijacks SMAD4 and SMAD2/3 to Drive Adult Granulosa Cell Tumors

Stine E. Weis-Banke, Mads Lerdrup, Daniela Kleine-Kohlbrecher, Faizaan Mohammad, Simone Sidoli, Ole N. Jensen, Toshihiko Yanase, Tomoko Nakamura, Akira Iwase, Anthe Stylianou, Nadeem R. Abu-Rustum, Carol Aghajanian, Robert Soslow, Arnaud Da Cruz Paula, Richard P. Koche, Britta Weigelt, Jesper Christensen, Kristian Helin, Paul A.C. Cloos
Journal: Cancer Research
Cancer Res (2020) 80 (17): 3466–3479.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-0259
Published: 02 September 2020
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Includes: Supplementary data
Journal Articles

Abstract 1122: Germline mutation prevalence in young adults with cancer

Zsofia K. Stadler, Anna Maio, Angelika Padunan, Yelena Kemel, Erin Salo-Mullen, Margaret Sheehan, Kimeisha Belanfanti, Prince R. Tejada, Ozge Birsoy, Diana Mandelker, Liying Zhang, Jesse Galle, Darren Feldman, Laura Boucai, Julia Glade Bender, Anna Piotrowski, Carol Aghajanian, Karen A. Cadoo, Maria I. Carlo, Michael Walsh, Yelena Janjigian, Eileen O'Reilly, Lisa M. DeAngelis, David B. Solit, Barry Taylor, Andrea Cercek, William Tap, Mark E. Robson, Michael F. Berger, Kenneth Offit, Luis A. Diaz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1122.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1122
Published: 15 August 2020
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Journal Articles

Abstract CT035: A phase Ib study of miransertib (ARQ 092) in combination with anastrozole in patients with PIK3CA or AKT1-mutant ER+ endometrial or ovarian cancer

David Hyman, Michael Bonafede, Roisin O'Cearbhaill, Rachel Grisham, Dmitriy Zamarin, William Tew, Carol Aghajanian, Karen Cadoo, Claire Friedman, Ron E. Savage, Feng Chai, Brian Schwartz, Vicky Makker
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT035.
DOI: https://doi.org/10.1158/1538-7445.AM2018-CT035
Published: 01 July 2018
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Journal Articles

Abstract CT008: Phase I study of the alpha specific PI3-Kinase inhibitor BYL719 and the poly (ADP-Ribose) polymerase (PARP) inhibitor olaparib in recurrent ovarian and breast cancer: Analysis of the dose escalation and ovarian cancer expansion cohort

Panagiotis A. Konstantinopoulos, William T. Barry, Michael Birrer, Shannon N. Westin, Sarah Farooq, Karen Cadoo, Christin Whalen, Weixiu Luo, Hui Liu, Carol Aghajanian, David B. Solit, Gordon B. Mills, Barry S. Taylor, Helen Won, Michael F. Berger, Sangeetha Palakurthi, Joyce F. Liu, Lew Cantley, Scott H. Kaufmann, Elizabeth M. Swisher, Alan D. D'Andrea, Eric Winer, Gerburg M. Wulf, Ursula A. Matulonis
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT008.
DOI: https://doi.org/10.1158/1538-7445.AM2017-CT008
Published: 01 July 2017
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Journal Articles

Abstract CT324: Phase I of oral BKM120 or BYL719 and olaparib for high-grade serous ovarian cancer or triple-negative breast cancer: Final results of the BKM120 plus olaparib cohort

Ursula A. Matulonis, Gerburg Wulf, William Barry, Michael Birrer, Shannon Westin, Tatum Spagnoletti, Katherine Bell-McGuinn, Elizabeth Obermayer, Christin Whalen, Carol Aghajanian, David Solit, Gordon Mills, Lewis Cantley, Eric Winer
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT324.
DOI: https://doi.org/10.1158/1538-7445.AM2015-CT324
Published: 01 August 2015
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Journal Articles

Posttranscriptional Regulation of Protein Expression in Human Epithelial Carcinoma Cells by Adenine-Uridine-Rich Elements in the 3′-Untranslated Region of Tumor Necrosis Factor-α Messenger RNA

Enhong Wang, Wei-Jun Ma, Carol Aghajanian, David R. Spriggs
Journal: Cancer Research
Cancer Res (1997) 57 (23): 5426–5433.
Published: 01 December 1997
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