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Carl G. Figdor
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Journal Articles

Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines

Ghaith Bakdash, Sonja I. Buschow, Mark A.J. Gorris, Altuna Halilovic, Stanleyson V. Hato, Annette E. Sköld, Gerty Schreibelt, Simone P. Sittig, Ruurd Torensma, Tjitske Duiveman-de Boer, Christoph Schröder, Evelien L. Smits, Carl G. Figdor, I. Jolanda M. de Vries
Journal: Cancer Research
Cancer Res (2016) 76 (15): 4332–4346.
https://doi.org/10.1158/0008-5472.CAN-15-1695
Published: 31 July 2016
View articletitled, Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines
Open the PDF for Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines in another window
Includes: Supplementary data
Journal Articles

T-cell Landscape in a Primary Melanoma Predicts the Survival of Patients with Metastatic Disease after Their Treatment with Dendritic Cell Vaccines

Angela Vasaturo, Altuna Halilovic, Kalijn F. Bol, Dagmar I. Verweij, Willeke A.M. Blokx, Cornelis J.A. Punt, Patricia J.T.A. Groenen, J. Han J.M. van Krieken, Johannes Textor, I. Jolanda M. de Vries, Carl G. Figdor
Journal: Cancer Research
Cancer Res (2016) 76 (12): 3496–3506.
https://doi.org/10.1158/0008-5472.CAN-15-3211
Published: 14 June 2016
View articletitled, T-cell Landscape in a Primary Melanoma Predicts the Survival of Patients with Metastatic Disease after Their Treatment with Dendritic Cell Vaccines
Open the PDF for T-cell Landscape in a Primary Melanoma Predicts the Survival of Patients with Metastatic Disease after Their Treatment with Dendritic Cell Vaccines in another window
Includes: Supplementary data
Journal Articles

Abstract 2120: Platinum-based cancer chemotherapeutics inhibit STAT signaling by blocking the SH2 domain.

W. Joost Lesterhuis, Stanleyson V. Hato, Carl G. Figdor, Susumu Takahashi, Cornelis J.A. Punt, Akira Asai, I. Jolanda M. De Vries
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2120.
https://doi.org/10.1158/1538-7445.AM2013-2120
Published: 15 April 2013
View articletitled, Abstract 2120: Platinum-based cancer chemotherapeutics inhibit STAT signaling by blocking the SH2 domain.
Journal Articles

Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients

Jurjen Tel, Erik H.J.G. Aarntzen, Tetsuro Baba, Gerty Schreibelt, Barbara M. Schulte, Daniel Benitez-Ribas, Otto C. Boerman, Sandra Croockewit, Wim J.G. Oyen, Michelle van Rossum, Gregor Winkels, Pierre G. Coulie, Cornelis J.A. Punt, Carl G. Figdor, I. Jolanda M. de Vries
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1063–1075.
https://doi.org/10.1158/0008-5472.CAN-12-2583
Published: 31 January 2013
View articletitled, Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients
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Includes: Supplementary data
Journal Articles

Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination

Erik H.J.G. Aarntzen, I. Jolanda M. De Vries, W. Joost Lesterhuis, Danita Schuurhuis, Joannes F.M. Jacobs, Kalijn Bol, Gerty Schreibelt, Roel Mus, Johannes H.W. De Wilt, John B.A.G. Haanen, Dirk Schadendorf, Alexandra Croockewit, Willeke A.M. Blokx, Michelle M. Van Rossum, William W. Kwok, Gosse J. Adema, Cornelis J.A. Punt, Carl G. Figdor
Journal: Cancer Research
Cancer Res (2013) 73 (1): 19–29.
https://doi.org/10.1158/0008-5472.CAN-12-1127
Published: 02 January 2013
View articletitled, Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination
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Includes: Supplementary data
Journal Articles

Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell–Based Vaccination in Metastatic Melanoma

Erik H.J.G. Aarntzen, Kalijn Bol, Gerty Schreibelt, Joannes F.M. Jacobs, W. Joost Lesterhuis, Michelle M. Van Rossum, Gosse J. Adema, Carl G. Figdor, Cornelis J.A. Punt, I. Jolanda M. De Vries
Journal: Cancer Research
Cancer Res (2012) 72 (23): 6102–6110.
https://doi.org/10.1158/0008-5472.CAN-12-2479
Published: 29 November 2012
View articletitled, Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell–Based Vaccination in Metastatic Melanoma
Open the PDF for Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell–Based Vaccination in Metastatic Melanoma in another window
Includes: Supplementary data
Journal Articles

Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells

Stefan Nierkens, Martijn H. den Brok, Zacharias Garcia, Susan Togher, Jori Wagenaars, Melissa Wassink, Louis Boon, Theo J. Ruers, Carl G. Figdor, Stephen P. Schoenberger, Gosse J. Adema, Edith M. Janssen
Journal: Cancer Research
Cancer Res (2011) 71 (20): 6428–6437.
https://doi.org/10.1158/0008-5472.CAN-11-2154
Published: 12 October 2011
View articletitled, Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells
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Journal Articles

Abstract 3823: Platinum anti-cancer drugs attenuate T cell-mediated immune suppression through STAT6/PD-L2

W. Joost Lesterhuis, Cornelis J.A. Punt, Dagmar Eleveld-Trancikova, Bas J.H. Jansen, Gerty Schreibelt, Annemiek De Boer, Gosse J. Adema, Carl G. Figdor, I. Jolanda M. De Vries
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3823.
https://doi.org/10.1158/1538-7445.AM10-3823
Published: 15 April 2010
View articletitled, Abstract 3823: Platinum anti-cancer drugs attenuate T cell-mediated immune suppression through STAT6/PD-L2
Journal Articles

In situ Expression of Tumor Antigens by Messenger RNA–Electroporated Dendritic Cells in Lymph Nodes of Melanoma Patients

Danita H. Schuurhuis, Pauline Verdijk, Gerty Schreibelt, Erik H.J.G. Aarntzen, Nicole Scharenborg, Annemiek de Boer, Mandy W.M.M. van de Rakt, Marieke Kerkhoff, Marie-Jeanne P. Gerritsen, Femke Eijckeler, Johannes J. Bonenkamp, Willeke Blokx, J. Han van Krieken, Otto C. Boerman, Wim J.G. Oyen, Cornelis J.A. Punt, Carl G. Figdor, Gosse J. Adema, I. Jolanda M. de Vries
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2927–2934.
https://doi.org/10.1158/0008-5472.CAN-08-3920
Published: 01 April 2009
View articletitled, In situ Expression of Tumor Antigens by Messenger RNA–Electroporated Dendritic Cells in Lymph Nodes of Melanoma Patients
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Journal Articles

In vivo Colocalization of Antigen and CpG within Dendritic Cells Is Associated with the Efficacy of Cancer Immunotherapy

Stefan Nierkens, Martijn H. den Brok, Roger P.M. Sutmuller, Oliver M. Grauer, Erik Bennink, Mary E. Morgan, Carl G. Figdor, Theo J.M. Ruers, Gosse J. Adema
Journal: Cancer Research
Cancer Res (2008) 68 (13): 5390–5396.
https://doi.org/10.1158/0008-5472.CAN-07-6023
Published: 01 July 2008
View articletitled, In vivo Colocalization of Antigen and CpG within Dendritic Cells Is Associated with the Efficacy of Cancer Immunotherapy
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Includes: Supplementary data
Journal Articles

Synergy between In situ Cryoablation and TLR9 Stimulation Results in a Highly Effective In vivo Dendritic Cell Vaccine

Martijn H.M.G.M. den Brok, Roger P.M. Sutmuller, Stefan Nierkens, Erik J. Bennink, Liza W.J. Toonen, Carl G. Figdor, Theo J.M. Ruers, Gosse J. Adema
Journal: Cancer Research
Cancer Res (2006) 66 (14): 7285–7292.
https://doi.org/10.1158/0008-5472.CAN-06-0206
Published: 18 July 2006
View articletitled, Synergy between In situ Cryoablation and TLR9 Stimulation Results in a Highly Effective In vivo Dendritic Cell Vaccine
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Journal Articles

In Situ Tumor Ablation Creates an Antigen Source for the Generation of Antitumor Immunity

Martijn H. M. G. M. den Brok, Roger P. M. Sutmuller, Robbert van der Voort, Erik J. Bennink, Carl G. Figdor, Theo J. M. Ruers, Gosse J. Adema
Journal: Cancer Research
Cancer Res (2004) 64 (11): 4024–4029.
https://doi.org/10.1158/0008-5472.CAN-03-3949
Published: 01 June 2004
View articletitled, In Situ Tumor Ablation Creates an Antigen Source for the Generation of Antitumor Immunity
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Journal Articles

Effective Migration of Antigen-pulsed Dendritic Cells to Lymph Nodes in Melanoma Patients Is Determined by Their Maturation State

I. Jolanda M. de Vries, Daniëlle J. E. B. Krooshoop, Nicole M. Scharenborg, W. Joost Lesterhuis, J. Heleen S. Diepstra, Goos N. P. van Muijen, Simon P. Strijk, Theo J. Ruers, Otto C. Boerman, Wim J. G. Oyen, Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor
Journal: Cancer Research
Cancer Res (2003) 63 (1): 12–17.
Published: 01 January 2003
View articletitled, Effective Migration of Antigen-pulsed Dendritic Cells to Lymph Nodes in Melanoma Patients Is Determined by Their Maturation State
Open the PDF for Effective Migration of Antigen-pulsed Dendritic Cells to Lymph Nodes in Melanoma Patients Is Determined by Their Maturation State in another window
Includes: Multimedia, Supplementary data
Journal Articles

Dendritic Cells Break Tolerance and Induce Protective Immunity against a Melanocyte Differentiation Antigen in an Autologous Melanoma Model

Marco W. J. Schreurs, Andreas A. O. Eggert, Annemiek J. de Boer, Joost L. M. Vissers, Thorbald van Hall, Rienk Offringa, Carl G. Figdor, Gosse J. Adema
Journal: Cancer Research
Cancer Res (2000) 60 (24): 6995–7001.
Published: 01 December 2000
View articletitled, Dendritic Cells Break Tolerance and Induce Protective Immunity against a Melanocyte Differentiation Antigen in an Autologous Melanoma Model
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Journal Articles

The Renal Cell Carcinoma-associated Antigen G250 Encodes a Human Leukocyte Antigen (HLA)-A2.1-restricted Epitope Recognized by Cytotoxic T Lymphocytes

Joost L. M. Vissers, I. Jolanda M. De Vries, Marco W. J. Schreurs, Linda P. H. Engelen, Egbert Oosterwijk, Carl G. Figdor, Gosse J. Adema
Journal: Cancer Research
Cancer Res (1999) 59 (21): 5554–5559.
Published: 01 November 1999
View articletitled, The Renal Cell Carcinoma-associated Antigen G250 Encodes a Human Leukocyte Antigen (HLA)-A2.1-restricted Epitope Recognized by Cytotoxic T Lymphocytes
Open the PDF for The Renal Cell Carcinoma-associated Antigen G250 Encodes a Human Leukocyte Antigen (HLA)-A2.1-restricted Epitope Recognized by Cytotoxic T Lymphocytes in another window
Journal Articles

Biodistribution and Vaccine Efficiency of Murine Dendritic Cells Are Dependent on the Route of Administration

Andreas A. O. Eggert, Marco W. J. Schreurs, Otto C. Boerman, Wim J. C. Oyen, Annemiek J. de Boer, Cornelis J. A. Punt, Carl G. Figdor, Gosse J. Adema
Journal: Cancer Research
Cancer Res (1999) 59 (14): 3340–3345.
Published: 15 July 1999
View articletitled, Biodistribution and Vaccine Efficiency of Murine Dendritic Cells Are Dependent on the Route of Administration
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Journal Articles

Constitutive Up-Regulation of Integrin-mediated Adhesion of Tumor-infiltrating Lymphocytes to Osteoblasts and Bone Marrow-derived Stromal Cells

Yoshiya Tanaka, Shinichiro Mine, Takeshi Hanagiri, Toru Hiraga, Isao Morimoto, Carl G. Figdor, Yvette van Kooyk, Hidehiro Ozawa, Toshitaka Nakamura, Kosei Yasumoto, Sumiya Eto
Journal: Cancer Research
Cancer Res (1998) 58 (18): 4138–4145.
Published: 01 September 1998
View articletitled, Constitutive Up-Regulation of Integrin-mediated Adhesion of Tumor-infiltrating Lymphocytes to Osteoblasts and Bone Marrow-derived Stromal Cells
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Journal Articles

Genetic Vaccination against the Melanocyte Lineage-specific Antigen gp100 Induces Cytotoxic T Lymphocyte-mediated Tumor Protection

Marco W. J. Schreurs, Annemiek J. de Boer, Carl G. Figdor, Gosse J. Adema
Journal: Cancer Research
Cancer Res (1998) 58 (12): 2509–2514.
Published: 01 June 1998
View articletitled, Genetic Vaccination against the Melanocyte Lineage-specific Antigen gp100 Induces Cytotoxic T Lymphocyte-mediated Tumor Protection
Open the PDF for Genetic Vaccination against the Melanocyte Lineage-specific Antigen gp100 Induces Cytotoxic T Lymphocyte-mediated Tumor Protection in another window
Journal Articles

Generation of Antimelanoma Cytotoxic T Lymphocytes from Healthy Donors after Presentation of Melanoma-associated Antigen-derived Epitopes by Dendritic Cells in Vitro

Alexander B. H. Bakker, Gill Marland, Annemiek J. de Boer, Richard J. F. Huijbens, Erik H. J. Danen, Gosse J. Adema, Carl G. Figdor
Journal: Cancer Research
Cancer Res (1995) 55 (22): 5330–5334.
Published: 01 November 1995
View articletitled, Generation of Antimelanoma Cytotoxic T Lymphocytes from Healthy Donors after Presentation of Melanoma-associated Antigen-derived Epitopes by Dendritic Cells in Vitro
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Journal Articles

Expression of Neural Cell Adhesion Molecule-related Sialoglycoprotein in Small Cell Lung Cancer and Neuroblastoma Cell Lines H69 and CHP-212

C. E. C. Kitty Moolenaar, Egbert J. Muller, Dick J. Schol, Carl G. Figdor, Elizabeth Bock, Dieter Bitter-Suermann, Rob J. A. M. Michalides
Journal: Cancer Research
Cancer Res (1990) 50 (4): 1102–1106.
Published: 01 February 1990
View articletitled, Expression of Neural Cell Adhesion Molecule-related Sialoglycoprotein in Small Cell Lung Cancer and Neuroblastoma Cell Lines H69 and CHP-212
Open the PDF for Expression of Neural Cell Adhesion Molecule-related Sialoglycoprotein in Small Cell Lung Cancer and Neuroblastoma Cell Lines H69 and CHP-212 in another window