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Journal Articles

A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges During Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer

Pauliina Kallio, Cinzia Bessone, Fatemeh Seyednasrollah, Jefim Brodkin, Marika Lassila, Jenny Högström, Alejandra González-Loyola, Tatiana V. Petrova, Caj Haglund, Kari Alitalo

Cancer Res (2025)

https://doi.org/10.1158/0008-5472.CAN-23-1851

Published: 22 January 2025

View article titled, A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges During Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer

Includes: Supplementary data

Journal Articles

Lipid Metabolic Reprogramming Extends beyond Histologic Tumor Demarcations in Operable Human Pancreatic Cancer

Juho Pirhonen, Ábel Szkalisity, Jaana Hagström, Yonghyo Kim, Ede Migh, Mária Kovács, Maarit Hölttä, Johan Peränen, Hanna Seppänen, Caj Haglund, Jeovanis Gil, Melinda Rezeli, Johan Malm, Peter Horvath, György Markó-Varga, Pauli Puolakkainen, Elina Ikonen

Cancer Res (2022) 82 (21): 3932–3949.

https://doi.org/10.1158/0008-5472.CAN-22-0396

Published: 02 November 2022

View article titled, Lipid Metabolic Reprogramming Extends beyond Histologic Tumor Demarcations in Operable Human Pancreatic Cancer

Includes: Supplementary data

Journal Articles

Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin

Topi A. Tervonen, Shishir M. Pant, Denis Belitškin, Johanna I. Englund, Katja Närhi, Caj Haglund, Panu E. Kovanen, Emmy W. Verschuren, Juha Klefström

Cancer Res (2021) 81 (6): 1513–1527.

https://doi.org/10.1158/0008-5472.CAN-20-1760

Published: 15 March 2021

View article titled, Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin

Includes: Supplementary data

Journal Articles

Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production

Silvia Gramolelli, Endrit Elbasani, Krista Tuohinto, Veijo Nurminen, Thomas Günther, Riikka E. Kallinen, Seppo P. Kaijalainen, Raquel Diaz, Adam Grundhoff, Caj Haglund, Joseph M. Ziegelbauer, Teijo Pellinen, Mark Bower, Mathias Francois, Päivi M. Ojala

Cancer Res (2020) 80 (15): 3116–3129.

https://doi.org/10.1158/0008-5472.CAN-19-3103

Published: 04 August 2020

View article titled, Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production

Includes: Supplementary data

Journal Articles

Abstract 5718: Outcome prediction in colorectal cancer using digitized tumor samples and machine learning

Dmitrii Bychkov, Riku Turkki, Caj Haglund, Nina Linder, Johan Lundin

Cancer Res (2017) 77 (13_Supplement): 5718.

https://doi.org/10.1158/1538-7445.AM2017-5718

Published: 01 July 2017

View article titled, Abstract 5718: Outcome prediction in colorectal cancer using digitized tumor samples and machine learning

Journal Articles

Abstract 1908: The Wnt-target Prox1 promotes colorectal cancer stem cell survival to fuel tumor growth

Zoltan Wiener, Ville Hyvönen, Jenny Högström, Tanja Holopainen, Arja Band, Pauliina Kallio, Olli Dufva, Caj Haglund, Olli Kruuna, Guillermo Oliver, Yinon Ben-Neriah, Kari Alitalo

Cancer Res (2014) 74 (19_Supplement): 1908.

https://doi.org/10.1158/1538-7445.AM2014-1908

Published: 01 October 2014

View article titled, Abstract 1908: The Wnt-target Prox1 promotes colorectal cancer stem cell survival to fuel tumor growth

Journal Articles

Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells

Cancer Res (2013) 73 (22): 6757–6769.

https://doi.org/10.1158/0008-5472.CAN-13-1002

Published: 14 November 2013

View article titled, Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells

Includes: Supplementary data

Journal Articles

Abstract 4645: CIP2A is a marker of reduced survival in serous ovarian cancer patients

Camilla Böckelman, Heini Lassus, Annabrita Hemmes, Arto Leminen, Jukka Westermarck, Caj Haglund, Ralf Bützow, Ari Ristimäki

Cancer Res (2010) 70 (8_Supplement): 4645.

https://doi.org/10.1158/1538-7445.AM10-4645

Published: 15 April 2010

View article titled, Abstract 4645: CIP2A is a marker of reduced survival in serous ovarian cancer patients

Journal Articles

Analysis of the Human Cancer Glycome Identifies a Novel Group of Tumor-Associated N-Acetylglucosamine Glycan Antigens

Tero Satomaa, Annamari Heiskanen, Iréne Leonardsson, Jonas Ångström, Anne Olonen, Maria Blomqvist, Noora Salovuori, Caj Haglund, Susann Teneberg, Jari Natunen, Olli Carpén, Juhani Saarinen

Cancer Res (2009) 69 (14): 5811–5819.

https://doi.org/10.1158/0008-5472.CAN-08-0289

Published: 15 July 2009

View article titled, Analysis of the Human Cancer Glycome Identifies a Novel Group of Tumor-Associated <em>N</em>-Acetylglucosamine Glycan Antigens

Includes: Supplementary data

Journal Articles

Regulation of 15-hydroxyprostaglandin dehydrogenase expression in gastric cancer

Alexandra Thiel, Aparna Ganesan, Antti NykA¤nen, Annabrita Hemmes, Hsin Tai, Caj Haglund, Tatiana Petrova, Ari RistimA¤ki

Cancer Res (2008) 68 (9_Supplement): 2224.

Published: 01 May 2008

View article titled, Regulation of 15-hydroxyprostaglandin dehydrogenase expression in gastric cancer

Journal Articles

The role of HuR in breast carcinogenesis

Mira Heinonen, Kaisa Salmenkivi, Marjut Leidenius, PA¤ivi HeikkilA¤, Caj Haglund, Ari RistimA¤ki

Cancer Res (2008) 68 (9_Supplement): 4710.

Published: 01 May 2008

View article titled, The role of HuR in breast carcinogenesis

Journal Articles

Cytoplasmic HuR Expression Is a Prognostic Factor in Invasive Ductal Breast Carcinoma

Mira Heinonen, Petri Bono, Kirsi Narko, Sung-Hee Chang, Johan Lundin, Heikki Joensuu, Henry Furneaux, Timothy Hla, Caj Haglund, Ari Ristimäki

Cancer Res (2005) 65 (6): 2157–2161.

https://doi.org/10.1158/0008-5472.CAN-04-3765

Published: 21 March 2005

View article titled, Cytoplasmic HuR Expression Is a Prognostic Factor in Invasive Ductal Breast Carcinoma

Journal Articles

Cytoplasmic HuR Expression Correlates with Poor Outcome and with Cyclooxygenase 2 Expression in Serous Ovarian Carcinoma

Tiina-Liisa Erkinheimo, Heini Lassus, Anna Sivula, Sibani Sengupta, Henry Furneaux, Timothy Hla, Caj Haglund, Ralf Butzow, Ari Ristimäki

Cancer Res (2003) 63 (22): 7591–7594.

Published: 21 November 2003

View article titled, Cytoplasmic HuR Expression Correlates with Poor Outcome and with Cyclooxygenase 2 Expression in Serous Ovarian Carcinoma

Journal Articles

Prognostic Significance of Elevated Cyclooxygenase-2 Expression in Breast Cancer

Ari Ristimäki, Anna Sivula, Johan Lundin, Mikael Lundin, Tiina Salminen, Caj Haglund, Heikki Joensuu, Jorma Isola

Cancer Res (2002) 62 (3): 632–635.

Published: 01 February 2002

View article titled, Prognostic Significance of Elevated Cyclooxygenase-2 Expression in Breast Cancer

Journal Articles

Elevation of Free β Subunit of Human Choriogonadotropin and Core β Fragment of Human Choriogonadotropin in the Serum and Urine of Patients with Malignant Pancreatic and Biliary Disease

Henrik Alfthan, Caj Haglund, Peter Roberts, Ulf-Håkan Stenman

Cancer Res (1992) 52 (17): 4628–4633.

Published: 01 September 1992

View article titled, Elevation of Free β Subunit of Human Choriogonadotropin and Core β Fragment of Human Choriogonadotropin in the Serum and Urine of Patients with Malignant Pancreatic and Biliary Disease

NARROW

A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges During Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer

Lipid Metabolic Reprogramming Extends beyond Histologic Tumor Demarcations in Operable Human Pancreatic Cancer

Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin

Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production

Abstract 5718: Outcome prediction in colorectal cancer using digitized tumor samples and machine learning

Abstract 1908: The Wnt-target Prox1 promotes colorectal cancer stem cell survival to fuel tumor growth

Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells

Abstract 4645: CIP2A is a marker of reduced survival in serous ovarian cancer patients

Analysis of the Human Cancer Glycome Identifies a Novel Group of Tumor-Associated N-Acetylglucosamine Glycan Antigens

Regulation of 15-hydroxyprostaglandin dehydrogenase expression in gastric cancer

The role of HuR in breast carcinogenesis

Cytoplasmic HuR Expression Is a Prognostic Factor in Invasive Ductal Breast Carcinoma

Cytoplasmic HuR Expression Correlates with Poor Outcome and with Cyclooxygenase 2 Expression in Serous Ovarian Carcinoma

Prognostic Significance of Elevated Cyclooxygenase-2 Expression in Breast Cancer

Elevation of Free β Subunit of Human Choriogonadotropin and Core β Fragment of Human Choriogonadotropin in the Serum and Urine of Patients with Malignant Pancreatic and Biliary Disease

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