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Journal Articles

Abstract 3559: Redirection of anti-virus immunity towards anti-tumor immunity using nanoparticle-induced immune tolerance for oncolytic adenovirus therapy

Dong Ho Shin, Hong Jiang, Debora Kim, Teresa T. Nguyen, Sagar Sohoni, Xuejun Fan, Yanhua Yi, Arie C. Van Wieren, Gheath Al-Atrash, Chantale Bernatchez, Ramon Alemany, Marta Alonso, Frederick Lang, Candelaria Gomez-Manzano, Bulent Ozpolat, Juan Fueyo

Cancer Res (2022) 82 (12_Supplement): 3559.

DOI: https://doi.org/10.1158/1538-7445.AM2022-3559

Published: 15 June 2022

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Journal Articles

Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression

Nora Pällmann, Ke Deng, Marte Livgård, Martina Tesikova, Yixin Jin, Nicolai Sebastian Frengen, Nermin Kahraman, Hamada M. Mokhlis, Bulent Ozpolat, Wanja Kildal, Havard Emil Danielsen, Ladan Fazli, Paul S. Rennie, Partha P. Banerjee, Aykut Üren, Yang Jin, Omer F. Kuzu, Fahri Saatcioglu

Cancer Res (2021) 81 (15): 4066–4078.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-3956

Published: 01 August 2021

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Includes: Supplementary data

Journal Articles

Abstract 3704: MicroRNA-3977 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting FoxM1

Selda Karamil, Nuray Altintas, Bulent Ozpolat

Cancer Res (2020) 80 (16_Supplement): 3704.

DOI: https://doi.org/10.1158/1538-7445.AM2020-3704

Published: 15 August 2020

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Journal Articles

Abstract 5985: MiR-329 mimic based nano-therapy inhibits growth and progression of triple negative breast cancer

Goknur Kara, Nermin Kahraman, Emir Baki Denkbas, George Calin, Bulent Ozpolat

Cancer Res (2020) 80 (16_Supplement): 5985.

DOI: https://doi.org/10.1158/1538-7445.AM2020-5985

Published: 15 August 2020

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Journal Articles

Abstract 1156: Skeletal muscle progenitor cell-derived exosomes have therapeutic potential in inhibition of prostate cancer cell proliferation

Krishna M. Sinha, Rozita Yarmand, Nermin Kahraman, Fahriye Duzagac, Gabriel Lopez, Bulent Ozpolat, Johnny Huard

Cancer Res (2019) 79 (13_Supplement): 1156.

DOI: https://doi.org/10.1158/1538-7445.AM2019-1156

Published: 01 July 2019

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Journal Articles

Abstract 2591: miR-193b is a novel regulator of Inhibition of Notch signaling by for targeting cancer stem cell and tumor microenvironment

Ummu Guven, Hamada Ahmed Mokhlis, Nermin Kahraman, Cristina Ivan, Fahriye Duzagac, Gabriel Lopez-Berestein, Gulperi Oktem, Bulent Ozpolat

Cancer Res (2019) 79 (13_Supplement): 2591.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2591

Published: 01 July 2019

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Journal Articles

Abstract 4787: New and potent small molecule as EF2K inhibitor: A novel EF2K inhibitor

Ferah Comert Onder, Mehmet Ay, Serdar Durdagi, Bulent Ozpolat, isik Kantarcioglu

Cancer Res (2019) 79 (13_Supplement): 4787.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4787

Published: 01 July 2019

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Journal Articles

Abstract 3563: Exosomal transfer of tumor-associated macrophage derived miR-6068 promote ovarian cancer progression

Seyda Baydogan, Jianting Sheng, Nermin Kahraman, Pinar Kanlikilicer, Hamada Ahmed Mokhlis, Sayra Dilmac, Stephen T. C. Wong, Bulent Ozpolat

Cancer Res (2019) 79 (13_Supplement): 3563.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3563

Published: 01 July 2019

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Journal Articles

Abstract 4262: MiR-873 is the master regulator of autophagy genes through a novel negative feedback mechanism mediated by Elongation factor 2 kinase (eEF-2K) and suppresses tumor growth and progression of triple negative breast cancer

Hamada Ahmed Mokhlis, Nermin Kahraman, Seyda Baydogan, Abdel-Aziz Hamed Abdel-Aziz, Ahmed Ashour, Cristina Ivan, Gabriel Lopez-Berestein, Bulent Ozpolat

Cancer Res (2019) 79 (13_Supplement): 4262.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4262

Published: 01 July 2019

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Journal Articles

Abstract 1981: M2-macrophage derived exosomes mediates tumor progression via GATA3-IL-4-IL-13 axis in ovarian cancer

Pinar Kanlikilicer, Amr Ahmed El-Arabey, Merve Denizli, Recep Bayraktar, Bulent Ozpolat, Gabriel Lopez-Berestein, Salama Abdu Salama, Adel Rashad Abd-Allah

Cancer Res (2019) 79 (13_Supplement): 1981.

DOI: https://doi.org/10.1158/1538-7445.AM2019-1981

Published: 01 July 2019

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Journal Articles

Abstract 3686: Regulatory role cancer stem cells (CSCs)-derived exosomal miRNAs in ovarian cancer growth and progression

Fahriye Duzagac, Gabriel Lopez-Berestein, Pinar Kanlikilicer, Cristian Rodriguez-Aguoya, Roberto Cardenas-Zuniga, Ummu Guven, Gulperi Oktem, Bulent Ozpolat

Cancer Res (2019) 79 (13_Supplement): 3686.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3686

Published: 01 July 2019

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Journal Articles

Abstract 1950: Targeted silencing of Na_V1.5 channel suppresses cell proliferation and invasion in ovarian cancer cells through inhibition of PI3K/AKT and Integrinβ-1/FAK/Src axis

Mumin Alper Erdogan, Bulent Ozpolat

Cancer Res (2018) 78 (13_Supplement): 1950.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1950

Published: 01 July 2018

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Journal Articles

Abstract 504: miR-484 acts as an “oncomiR” in triple negative breast cancer cells to promote tumor growth and progression by targeting HOXA5

Nashwa N. Kabil, Recep Bayraktar, Cristina Ivan, Nermin Kahraman, Hamada A. Mokhlis, George A. Calin, Gabriel Lopez-Berestein, Bulent Ozpolat

Cancer Res (2018) 78 (13_Supplement): 504.

DOI: https://doi.org/10.1158/1538-7445.AM2018-504

Published: 01 July 2018

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Journal Articles

Abstract 507: MiR-873 functions as a potential tumor suppressor in pancreatic cancer by targeting KRAS

Hamada A. Mokhlis, Recep Bayraktar, Nashwa N. Kabil, Nermin Kahraman, Richard Bouchard, Tamer Abdelghany, Ahmed Ashour, Abdel-Aziz H. Abdel-Aziz, George A. Calin, Gabriel Lopez-Berestein, Bulent Ozpolat

Cancer Res (2018) 78 (13_Supplement): 507.

DOI: https://doi.org/10.1158/1538-7445.AM2018-507

Published: 01 July 2018

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Journal Articles

Abstract 5717: PKR promotes EphA2 and other proteins degradation and is predictor of survival in lung cancer

Apar Pataer, Ruping Shao, Bulent Ozpolat, Bingliang Fang, Stephen G. Swisher

Cancer Res (2017) 77 (13_Supplement): 5717.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5717

Published: 01 July 2017

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Journal Articles

Abstract 1125: Eukaryotic Elongation Factor 2 Kinase (eEF-2K) is a novel therapeutic target in BRCA1+ mutated breast cancer

Elif Asik, Nermin Kahraman, Tulin Guray, Murvet Volkan, Gabriel Lopez-Berestein, Bulent Ozpolat

Cancer Res (2017) 77 (13_Supplement): 1125.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1125

Published: 01 July 2017

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Journal Articles

Abstract 3249: Thymoquinone inhibits elongation factor 2 kinase signaling axis by inducing tumor suppressor miR-603 in triple negative breast cancer cells

Nashwa N. Kabil, Recep Bayraktar, Nermin Kahraman, Bulent Ozpolat

Cancer Res (2017) 77 (13_Supplement): 3249.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3249

Published: 01 July 2017

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Journal Articles

Abstract 1154: Targeted silencing of elongation factor 2 kinase (EF2K) suppresses invasion, cell proliferation and growth in an orthotopic model of ovarian cancer

Mumin Alper Erdogan, Bulent Ozpolat

Cancer Res (2017) 77 (13_Supplement): 1154.

DOI: https://doi.org/10.1158/1538-7445.AM2017-1154

Published: 01 July 2017

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Journal Articles

Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells

Pinar Kanlikilicer, Mohammed H. Rashed, Recep Bayraktar, Rahul Mitra, Cristina Ivan, Burcu Aslan, Xinna Zhang, Justyna Filant, Andreia M. Silva, Cristian Rodriguez-Aguayo, Emine Bayraktar, Martin Pichler, Bulent Ozpolat, George A. Calin, Anil K. Sood, Gabriel Lopez-Berestein

Cancer Res (2016) 76 (24): 7194–7207.

DOI: https://doi.org/10.1158/0008-5472.CAN-16-0714

Published: 15 December 2016

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Includes: Supplementary data

Journal Articles

Abstract 2176: Targeting eEF-2Kinase by thymoquinone in triple negative breast cancer

Nashwa N. Kabil, Recep Bayraktar, Nermin Kahraman, Bulent Ozpolat

Cancer Res (2016) 76 (14_Supplement): 2176.

DOI: https://doi.org/10.1158/1538-7445.AM2016-2176

Published: 15 July 2016

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NARROW

Abstract 3559: Redirection of anti-virus immunity towards anti-tumor immunity using nanoparticle-induced immune tolerance for oncolytic adenovirus therapy

Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression

Abstract 3704: MicroRNA-3977 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting FoxM1

Abstract 5985: MiR-329 mimic based nano-therapy inhibits growth and progression of triple negative breast cancer

Abstract 1156: Skeletal muscle progenitor cell-derived exosomes have therapeutic potential in inhibition of prostate cancer cell proliferation

Abstract 2591: miR-193b is a novel regulator of Inhibition of Notch signaling by for targeting cancer stem cell and tumor microenvironment

Abstract 4787: New and potent small molecule as EF2K inhibitor: A novel EF2K inhibitor

Abstract 3563: Exosomal transfer of tumor-associated macrophage derived miR-6068 promote ovarian cancer progression

Abstract 4262: MiR-873 is the master regulator of autophagy genes through a novel negative feedback mechanism mediated by Elongation factor 2 kinase (eEF-2K) and suppresses tumor growth and progression of triple negative breast cancer

Abstract 1981: M2-macrophage derived exosomes mediates tumor progression via GATA3-IL-4-IL-13 axis in ovarian cancer

Abstract 3686: Regulatory role cancer stem cells (CSCs)-derived exosomal miRNAs in ovarian cancer growth and progression

Abstract 1950: Targeted silencing of Na_V1.5 channel suppresses cell proliferation and invasion in ovarian cancer cells through inhibition of PI3K/AKT and Integrinβ-1/FAK/Src axis

Abstract 504: miR-484 acts as an “oncomiR” in triple negative breast cancer cells to promote tumor growth and progression by targeting HOXA5

Abstract 507: MiR-873 functions as a potential tumor suppressor in pancreatic cancer by targeting KRAS

Abstract 5717: PKR promotes EphA2 and other proteins degradation and is predictor of survival in lung cancer

Abstract 1125: Eukaryotic Elongation Factor 2 Kinase (eEF-2K) is a novel therapeutic target in BRCA1+ mutated breast cancer

Abstract 3249: Thymoquinone inhibits elongation factor 2 kinase signaling axis by inducing tumor suppressor miR-603 in triple negative breast cancer cells

Abstract 1154: Targeted silencing of elongation factor 2 kinase (EF2K) suppresses invasion, cell proliferation and growth in an orthotopic model of ovarian cancer

Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells

Abstract 2176: Targeting eEF-2Kinase by thymoquinone in triple negative breast cancer

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