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Bruce E. Johnson
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Journal Articles

Abstract 3890: Sequencing of 888 pediatric solid tumors informs precision oncology trial design and data sharing initiatives in pediatric cancer

Suzanne J. Forrest, Hersh Gupta, Abigail Ward, Yvonne Li, Duong Doan, Alyaa Al-Ibraheemi, Sanda Alexandrescu, Pratiti Bandopadhayay, Suzanne Shusterman, Elizabeth A. Mullen, Natalie Collins, Susan N. Chi, Karen D. Wright, Priti Kumari, Tali Mazor, Keith L. Ligon, Priyanka Shivdasani, Phani Davineni, Monica Manam, Richard L. Schilsky, Suanna S. Bruinooge, Jaime M. Guidry Auvil, Ethan Cerami, Barrett J. Rollins, Matthew L. Meyerson, Neal I. Lindeman, Laura MacConaill, Bruce E. Johnson, Andrew D. Cherniack, Alanna J. Church, Katherine A. Janeway
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3890.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3890
Published: 15 June 2022
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Journal Articles

Abstract CT112: AI-powered and manual assessment of PD-L1 are comparable in predicting response to neoadjuvant atezolizumab in patients (pts) with resectable non-squamous, non-small cell lung cancer (NSCLC)

John Abel, Christopher Rivard, Filip Kos, Guillaume Chhor, Yi Liu, Jennifer Giltnane, Sara Hoffman, Murray Resnick, Cyrus Hedvat, Amaro Taylor-Weiner, Farah Khalil, Alan Nicholas, Gregory A. Fishbein, Lynette M. Sholl, Natasha Rekhtman, Stephanie Hennek, Ilan Wapinski, Ann Johnson, Michael Montalto, Katja Schulze, Bruce E. Johnson, David P. Carbone, Konstantin Shilo, Andrew H. Beck, Sanja Dacic, William D. Travis, Ignacio Wistuba
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT112.
DOI: https://doi.org/10.1158/1538-7445.AM2022-CT112
Published: 15 June 2022
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Journal Articles

Abstract CT037: Canakinumab in combination with first-line (1L) pembrolizumab plus chemotherapy for advanced non-small cell lung cancer (aNSCLC): Results from the CANOPY-1 phase 3 trial

Daniel S. Tan, Enriqueta Felip, Gilberto Castro, Benjamin J. Solomon, Alastair Greystoke, Byoungchul Cho, Manuel Cobo, Tae Min Kim, Sandip Ganguly, Enric Carcereny, Luis Paz-Ares, Jaafar Bennouna, Marina Garassino, Michael Schenker, Sang-We Kim, Bijoyesh Mookerje, Vanessa Q. Passos, Stephanie Deudon, Bharani Dharan, Yuanbo Song, Rafael Caparica, Bruce E. Johnson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT037.
DOI: https://doi.org/10.1158/1538-7445.AM2022-CT037
Published: 15 June 2022
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Journal Articles

Abstract 3893: Rare FGFR oncogenic alterations in sequenced pediatric solid and brain tumors suggest FGFR is a relevant molecular target in childhood cancer

Lorena Lazo De La Vega, Alanna J. Church, Hannah Comeau, Wenjun Kang, AeRang Kim, Navin R. Pinto, Margaret E. Macy, Luke D. Maese, Steven G. DuBois, Bruce E. Johnson, Katherine A. Janeway, Suzanne J. Forrest
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3893.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3893
Published: 15 June 2022
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Journal Articles

Abstract PD6-03: Spatio-molecular dissection of the breast cancer metastatic microenvironment

Daniel L Abravanel, Johanna Klughammer, Timothy Blosser, Yury Goltsev, Sizun Jiang, Yunjao Bai, Evan Murray, Shahar Alon, Yi Cui, Daniel R Goodwin, Anubhav Sinha, Ofir Cohen, Michal Slyper, Orr Ashenberg, Danielle Dionne, Judit Jané-Valbuena, Caroline BM Porter, Asa Segerstolpe, Julia Waldman, Sébastien Vigneau, Karla Helvie, Allison Frangieh, Laura DelloStritto, Miraj Patel, Jingyi We, Kathleen Pfaff, Nicole Cullen, Ana Lako, Madison Turner, Isaac Wakiro, Sara Napolitano, Abhay Kanodia, Rebecca Ortiz, Colin MacKichan, Stephanie Inga, Judy Chen, Aaron R Thorner, Asaf Rotem, Scott Rodig, Fei Chen, Edward S Boyden, Garry P Nolan, Xiaowei Zhuang, Orit Rozenblatt-Rosen, Bruce E Johnson, Aviv Regev, Nikhil Wagle
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD6-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-PD6-03
Published: 15 February 2022
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Journal Articles

Abstract 370: Smoking history as an independent predictor for immune checkpoint inhibitors (ICIs) in metastatic non-small cell lung cancer (NSCLC)

Xinan Wang, Biagio Ricciuti, Joao V. Alessi, Tom Nguyen, Mark M. Awad, Xihong Lin, Bruce E. Johnson, David C. Christiani
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 370.
DOI: https://doi.org/10.1158/1538-7445.AM2021-370
Published: 01 July 2021
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Journal Articles

Association between Smoking History and Tumor Mutation Burden in Advanced Non–Small Cell Lung Cancer

Xinan Wang, Biagio Ricciuti, Tom Nguyen, Xihao Li, Michael S. Rabin, Mark M. Awad, Xihong Lin, Bruce E. Johnson, David C. Christiani
Journal: Cancer Research
Cancer Res (2021) 81 (9): 2566–2573.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-3991
Published: 01 May 2021
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Includes: Supplementary data
Journal Articles

Abstract PR01: A cancer cell program promotes T-cell exclusion and resistance to checkpoint blockade

Parin Shah, Michael Cuoco, Mei-Ju Su, Johannes Melms, Rachel Leeson, Abhay Kanodia, Shaolin Mei, Jia-Ren Lin, Shu Wang, Bokang Rabasha, David Liu, Alex K. Shalek, Itay Tirosh, Peter K. Sorger, Kai Wucherpfennig, Eliezer M. Van Allen, Dirk Schadendorf, Bruce E. Johnson, Asaf Rotem, Orit Rozenblatt-Rosen, Levi A. Garraway, Charles H. Yoon, Benjamin Izar, Aviv Regev, Livnat Jerby-Arnon
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): PR01.
DOI: https://doi.org/10.1158/1538-7445.MEL2019-PR01
Published: 02 October 2020
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Journal Articles

Abstract CT214: CANOPY-1: Safety run-in results from phase (ph) 3 study of canakinumab (CAN) or placebo (PBO) in combination (comb) with pembrolizumab (PEM) plus platinum-based doublet chemotherapy (Ctx) as 1st line therapy in patients (pts) with advanced or metastatic NSCLC

Bruce E. Johnson, Tae Min Kim, T. Jeroen N. Hiltermann, Fabrice Barlesi, Christian Grohe, Yasushi Goto, Orvar Gunnarsson, Tobias Overbeck, Noemi Reguart, Martin Wermke, Gilberto Castro Castro, Enriqueta Felip, Alastair Greystoke, Benjamin J. Solomon, Stephanie Deudon, Anne-Laure Louveau, Vanessa Passos, Daniel SW Tan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT214.
DOI: https://doi.org/10.1158/1538-7445.AM2020-CT214
Published: 15 August 2020
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Journal Articles

Abstract CT286: CANOPY program clinical trials: Canakinumab (Cana) in patients (pts) with non-small cell lung cancer (NSCLC)

Luis Paz-Ares, Edward B. Garon, Tony Mok, Andrea Ardizzoni, Fabrice Barlesi, Byoung Chul Cho, Gilberto de Castro, Pedro De Marchi, Enriqueta Felip, Yasushi Goto, Alastair Greystoke, Shun Lu, Darren Wan-Teck Lim, Martin Reck, Benjamin J. Solomon, David R. Spigel, Daniel SW Tan, Michael Thomas, James Chih-Hsin Yang, Jay M. Lee, Pilar Garrido, Edward Kim, Bruce E. Johnson
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT286.
DOI: https://doi.org/10.1158/1538-7445.AM2020-CT286
Published: 15 August 2020
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Journal Articles

Abstract 2063: Deep natural language processing for automated ascertainment of cancer outcomes from clinician progress notes

Kenneth L. Kehl, Wenxin Xu, Haitham A. Elmarakeby, Michael J. Hassett, Jackson Nyman, Bruce E. Johnson, Eliezer M. Van Allen, Deb Schrag
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2063.
DOI: https://doi.org/10.1158/1538-7445.AM2020-2063
Published: 15 August 2020
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Journal Articles

Abstract 4727: Genomic characterization of brain metastases reveals divergent evolution and metastasis specific mutations

Priscilla K. Brastianos, Scott L. Carter, Sandro Santagata, Amaro Taylor-Weiner, Robert T. Jones, Eli Van Allen, Keith L. Ligon, Josep Tabernero, Joan Seoane, Elena Martinez-Saez, Daniel Cahill, William T. Curry, Ian F. Dunn, Sun Ha Paek, Paul Van Hummelen, Aaron R. Thorner, Bruce E. Johnson, Nancy U. Lin, Toni K. Choueiri, Michael S. Rabin, Rameen Beroukhim, Anat Stemmer-Rachamimov, Matthew Meyerson, Levi Garraway, Tracy Batchelor, Jose Baselga, David N. Louis, William C. Hahn, Gad Getz
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4727.
DOI: https://doi.org/10.1158/1538-7445.AM2015-4727
Published: 01 August 2015
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Journal Articles

Abstract CT343: Phase II study of low-dose rate thoracic radiotherapy for treatment of intrathoracic relapsed or progressive small cell lung cancer

Guy C. Jones, James B. Mitchell, Bruce E. Johnson, Kevin Camphausen, Eli Glatstein, Charles B. Simone
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): CT343.
DOI: https://doi.org/10.1158/1538-7445.AM2014-CT343
Published: 01 October 2014
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Journal Articles

Abstract NG03: Genomic characterization of 101 brain metastases and paired primary tumors reveals patterns of clonal evolution and selection of driver mutations

Priscilla K. Brastianos, Scott L. Carter, Sandro Santagata, Amaro Taylor-Weiner, Robert T. Jones, Peleg M. Horowitz, Keith L. Ligon, Joan Seaone, Elena Martinez-Saez, Josep Tabernero, Daniel P. Cahill, Sun-Ha Paek, Ian F. Dunn, Bruce E. Johnson, Toni K. Choueiri, Michael S. Rabin, Eric P. Winer, Nancy U. Lin, Paul Van Hummelen, Anat Stemmer-Rachamimov, Rameen Beroukhim, David L. Louis, Tracy T. Batchelor, Jose Baselga, Gad Getz, William C. Hahn
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): NG03.
DOI: https://doi.org/10.1158/1538-7445.AM2014-NG03
Published: 01 October 2014
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Journal Articles

Cetuximab Response of Lung Cancer–Derived EGF Receptor Mutants Is Associated with Asymmetric Dimerization

Jeonghee Cho, Liang Chen, Naveen Sangji, Takafumi Okabe, Kimio Yonesaka, Joshua M. Francis, Richard J. Flavin, William Johnson, Jihyun Kwon, Soyoung Yu, Heidi Greulich, Bruce E. Johnson, Michael J. Eck, Pasi A. Jänne, Kwok-Kin Wong, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2013) 73 (22): 6770–6779.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-1145
Published: 14 November 2013
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Includes: Supplementary data
Journal Articles

Abstract PL04-01: Improving patient outcomes in lung cancer by targeting different driver mutations

Bruce E. Johnson
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): PL04-01.
DOI: https://doi.org/10.1158/1538-7445.AM2011-PL04-01
Published: 15 April 2011
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Journal Articles

Abstract 4958: Presence of amphiregulin autocrine-loop predicts sensitivity of EGFR wild type cancers to gefitinib and cetuximab

Kimio Yonesaka, Kreshnik Zejnullahu, Alison J Homes, Bruce E Johnson, Pasi A Janne
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4958.
DOI: https://doi.org/10.1158/1538-7445.AM2008-4958
Published: 15 May 2008
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Journal Articles

Mutations in BRAF and KRAS Converge on Activation of the Mitogen-Activated Protein Kinase Pathway in Lung Cancer Mouse Models

Hongbin Ji, Zhenxiong Wang, Samanthi A. Perera, Danan Li, Mei-Chih Liang, Sara Zaghlul, Kate McNamara, Liang Chen, Mitchell Albert, Yanping Sun, Ruqayyah Al-Hashem, Lucian R. Chirieac, Robert Padera, Roderick T. Bronson, Roman K. Thomas, Levi A. Garraway, Pasi A. Jänne, Bruce E. Johnson, Lynda Chin, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2007) 67 (10): 4933–4939.
DOI: https://doi.org/10.1158/0008-5472.CAN-06-4592
Published: 17 May 2007
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Includes: Supplementary data
Journal Articles

Epidermal Growth Factor Receptor Mutations in Patients with Non–Small Cell Lung Cancer

Bruce E. Johnson, Pasi A. Jänne
Journal: Cancer Research
Cancer Res (2005) 65 (17): 7525–7529.
DOI: https://doi.org/10.1158/0008-5472.CAN-05-1257
Published: 01 September 2005
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Journal Articles

Differential effects of gefitinib and cetuximab on EGFR mutant non-small cell lung cancers (NSCLC)

Toru Mukohara, Jeffrey A. Engelman, Neal Lindeman, Balazs Halmos, Bruce E. Johnson, Pasi A. Jänne
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 508.
Published: 01 May 2005
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