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Britta M. Jacobsen
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Journal Articles

Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of ESR1-Mutant Breast Cancer

Michelle M. Williams, Nicole S. Spoelstra, Spencer Arnesen, Kathleen I. O'Neill, Jessica L. Christenson, Jordan Reese, Kathleen C. Torkko, Andrew Goodspeed, Emmanuel Rosas, Toru Hanamura, Sharon B. Sams, Zheqi Li, Steffi Oesterreich, Rebecca B. Riggins, Britta M. Jacobsen, Anthony Elias, Jason Gertz, Jennifer K. Richer
Journal: Cancer Research
Cancer Res (2021) 81 (3): 732–746.
https://doi.org/10.1158/0008-5472.CAN-20-1200
Published: 01 February 2021
View article titled, Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of <em>ESR1</em>-Mutant Breast Cancer
Open the PDF for Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of <em>ESR1</em>-Mutant Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract P6-04-13: Preclinical and clinical analyses of estrogen receptor alpha mutant metastatic breast cancer

Jennifer K Richer, Michelle M Williams, Nicole S Spoelstra, Spencer Arnesen, Jessica L Christenson, Kathleen O’Neill, Jordan M Reese, Zannel D Blanchard, Toru Hanamura, Britta M Jacobsen, Jason Gertz, Anthony Elias
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P6-04-13.
https://doi.org/10.1158/1538-7445.SABCS19-P6-04-13
Published: 15 February 2020
View article titled, Abstract P6-04-13: Preclinical and clinical analyses of estrogen receptor alpha mutant metastatic breast cancer
Journal Articles

Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures

Nilgun Tasdemir, Emily A. Bossart, Zheqi Li, Li Zhu, Matthew J. Sikora, Kevin M. Levine, Britta M. Jacobsen, George C. Tseng, Nancy E. Davidson, Steffi Oesterreich
Journal: Cancer Research
Cancer Res (2018) 78 (21): 6209–6222.
https://doi.org/10.1158/0008-5472.CAN-18-1416
Published: 01 November 2018
View article titled, Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures
Open the PDF for Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures in another window
Includes: Supplementary data
Journal Articles

Breast Cancer Suppression by Progesterone Receptors Is Mediated by Their Modulation of Estrogen Receptors and RNA Polymerase III

Jessica Finlay-Schultz, Austin E. Gillen, Heather M. Brechbuhl, Joshua J. Ivie, Shawna B. Matthews, Britta M. Jacobsen, David L. Bentley, Peter Kabos, Carol A. Sartorius
Journal: Cancer Research
Cancer Res (2017) 77 (18): 4934–4946.
https://doi.org/10.1158/0008-5472.CAN-16-3541
Published: 14 September 2017
View article titled, Breast Cancer Suppression by Progesterone Receptors Is Mediated by Their Modulation of Estrogen Receptors and RNA Polymerase III
Open the PDF for Breast Cancer Suppression by Progesterone Receptors Is Mediated by Their Modulation of Estrogen Receptors and RNA Polymerase III in another window
Includes: Supplementary data
Journal Articles

Abstract P3-04-06: Inhibiting androgen receptor nuclear localization decreases estrogen receptor (ER) activity and tumor growth in ER+ breast cancer

Nicholas C D'Amato, Britta M Jacobsen, Dawn R Cochrane, Nicole S Spoelstra, Beatrice L Babbs, Anthony Elias, Jennifer K Richer
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P3-04-06.
https://doi.org/10.1158/1538-7445.SABCS14-P3-04-06
Published: 01 May 2015
View article titled, Abstract P3-04-06: Inhibiting androgen receptor nuclear localization decreases estrogen receptor (ER) activity and tumor growth in ER+ breast cancer
Journal Articles

Abstract P3-04-02: Multiple subtypes of triple negative breast cancer are dependent on androgen receptor

Valerie N Barton, Nicholas C D'Amato, Michael A Gordon, Britta M Jacobsen, Jennifer K Richer
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P3-04-02.
https://doi.org/10.1158/1538-7445.SABCS14-P3-04-02
Published: 01 May 2015
View article titled, Abstract P3-04-02: Multiple subtypes of triple negative breast cancer are dependent on androgen receptor
Journal Articles

Abstract 4756: Elucidating the role of AR in breast cancer .

Nicholas C. D'Amato, Haihua Gu, Dawn R. Cochrane, Sebastian Bernales, Britta M. Jacobsen, Paul Jedlicka, Kathleen C. Torkko, Susan M. Edgerton, Ann D. Thor, Anthony D. Elias, Andrew A. Protter, Jennifer K. Richer
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4756.
https://doi.org/10.1158/1538-7445.AM2013-4756
Published: 15 April 2013
View article titled, Abstract 4756: Elucidating the role of AR in breast cancer .
Journal Articles

Abstract 1104: Malignant stroma regulates luminal breast cancer-cell growth versus basal breast cancer cell migration through different growth factor pathways.

Mauricio P. Pinto, Britta M. Jacobsen, Kathryn B. Horwitz
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1104.
https://doi.org/10.1158/1538-7445.AM2013-1104
Published: 15 April 2013
View article titled, Abstract 1104: Malignant stroma regulates luminal breast cancer-cell growth versus basal breast cancer cell migration through different growth factor pathways.
Journal Articles

Abstract LB-109: MDV3100, an androgen receptor signaling inhibitor, inhibits tumor growth in breast cancer preclinical models regardless of estrogen receptor status

Dawn R. Cochrane, Britta M. Jacobsen, Diana M. Cittelly, Erin N. Howe, Annie Jean, Nicole S. Spoelstra, Sebastian Bernales, Andrew A. Protter, Anthony D. Elias, Jennifer K. Richer
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-109.
https://doi.org/10.1158/1538-7445.AM2012-LB-109
Published: 15 April 2012
View article titled, Abstract LB-109: MDV3100, an androgen receptor signaling inhibitor, inhibits tumor growth in breast cancer preclinical models regardless of estrogen receptor status
Journal Articles

Tissue-Specific Pathways for Estrogen Regulation of Ovarian Cancer Growth and Metastasis

Monique A. Spillman, Nicole G. Manning, Wendy W. Dye, Carol A. Sartorius, Miriam D. Post, Joshua Chuck Harrell, Britta M. Jacobsen, Kathryn B. Horwitz
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8927–8936.
https://doi.org/10.1158/0008-5472.CAN-10-1238
Published: 31 October 2010
View article titled, Tissue-Specific Pathways for Estrogen Regulation of Ovarian Cancer Growth and Metastasis
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Includes: Supplementary data
Journal Articles

Vascular Endothelial Growth Factor Secreted by Activated Stroma Enhances Angiogenesis and Hormone-Independent Growth of Estrogen Receptor–Positive Breast Cancer

Mauricio P. Pinto, Melanie M. Badtke, Michelle L. Dudevoir, J. Chuck Harrell, Britta M. Jacobsen, Kathryn B. Horwitz
Journal: Cancer Research
Cancer Res (2010) 70 (7): 2655–2664.
https://doi.org/10.1158/0008-5472.CAN-09-4373
Published: 31 March 2010
View article titled, Vascular Endothelial Growth Factor Secreted by Activated Stroma Enhances Angiogenesis and Hormone-Independent Growth of Estrogen Receptor–Positive Breast Cancer
Open the PDF for Vascular Endothelial Growth Factor Secreted by Activated Stroma Enhances Angiogenesis and Hormone-Independent Growth of Estrogen Receptor–Positive Breast Cancer in another window
Journal Articles

Spontaneous Fusion with, and Transformation of Mouse Stroma by, Malignant Human Breast Cancer Epithelium

Britta M. Jacobsen, J. Chuck Harrell, Paul Jedlicka, Virginia F. Borges, Marileila Varella-Garcia, Kathryn B. Horwitz
Journal: Cancer Research
Cancer Res (2006) 66 (16): 8274–8279.
https://doi.org/10.1158/0008-5472.CAN-06-1456
Published: 15 August 2006
View article titled, Spontaneous Fusion with, and Transformation of Mouse Stroma by, Malignant Human Breast Cancer Epithelium
Open the PDF for Spontaneous Fusion with, and Transformation of Mouse Stroma by, Malignant Human Breast Cancer Epithelium in another window
Includes: Multimedia, Supplementary data