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Brinton Seashore-Ludlow
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Journal Articles

Abstract 6612: Data-driven hallmarks of cancer as a new paradigm for precision medicine: multi-omics and functional profiling in acute myeloid leukemia

Tom Erkers, Nona Struyf, Tojo James, Francesco Marabita, Mattias Vesterlund, Nghia Vu, Cornelia Arnroth, Albin Österroos, Anna Bohlin, Sofia Bengtzén, Matthias Stahl, Rozbeh Jafari, Lukas Orre, Yudi Pawitan, Brinton Seashore-Ludlow, Janne Lehtiö, Sören Lehmann, Päivi Östling, Olli Kallioniemi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6612.
https://doi.org/10.1158/1538-7445.AM2023-6612
Published: 04 April 2023
View article titled, Abstract 6612: Data-driven hallmarks of cancer as a new paradigm for precision medicine: multi-omics and functional profiling in acute myeloid leukemia
Journal Articles

Abstract 4578: Miniaturized and multiplexed evaluation of NK cell cytotoxicity and infiltration in patient-derived sarcoma spheroids using a novel multichambered microwell chip

Valentina Carannante, Niklas Sandström, Karl Olofsson, Shi Yong Neo, Patrick Albert Sandoz, Hanna Van Ooijen, Quentin Verron, Jacopo Fontana, Damien Toullec, Elisabeth Moussaud-Lamodière, Brinton Seashore-Ludlow, Thomas Frisk, Madoka Takai, Päivi Östling, Felix Haglund, Andreas Lundqvist, Martin Wiklund, Björn Önfelt
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4578.
https://doi.org/10.1158/1538-7445.AM2023-4578
Published: 04 April 2023
View article titled, Abstract 4578: Miniaturized and multiplexed evaluation of NK cell cytotoxicity and infiltration in patient-derived sarcoma spheroids using a novel multichambered microwell chip
Journal Articles

Abstract 1890: Development of the drug efficacy testing in ex vivo 3D cultures (DETECT) platform and its application to functional precision medicine in ovarian cancer

Emma Åkerlund, Greta Gudoityte, Elisabeth Moussaud Lamodiere, Joseph Carlson, Emelie Wallin, Josefin Fernebro, Olli Kallioniemi, Päivi Östling, Ulrika Joneborg, Brinton Seashore-Ludlow
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1890.
https://doi.org/10.1158/1538-7445.AM2022-1890
Published: 15 June 2022
View article titled, Abstract 1890: Development of the drug efficacy testing in <em>ex vivo</em> 3D cultures (DETECT) platform and its application to functional precision medicine in ovarian cancer
Journal Articles

MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia

Kumar Sanjiv, José Manuel Calderón-Montaño, Therese M. Pham, Tom Erkers, Viktoriia Tsuber, Ingrid Almlöf, Andreas Höglund, Yaser Heshmati, Brinton Seashore-Ludlow, Akhilesh Nagesh Danda, Helge Gad, Elisee Wiita, Camilla Göktürk, Azita Rasti, Stefanie Friedrich, Anders Centio, Montserrat Estruch, Thea Kristin Våtsveen, Nona Struyf, Torkild Visnes, Martin Scobie, Tobias Koolmeister, Martin Henriksson, Olov Wallner, Teresa Sandvall, Sören Lehmann, Kim Theilgaard-Mönch, Mathew J. Garnett, Päivi Östling, Julian Walfridsson, Thomas Helleday, Ulrika Warpman Berglund
Journal: Cancer Research
Cancer Res (2021) 81 (22): 5733–5744.
https://doi.org/10.1158/0008-5472.CAN-21-0061
Published: 15 November 2021
View article titled, MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia
Open the PDF for MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

Abstract 2476: DiSCoVERing innovative therapies for rare tumors: Combining genetically accurate disease models with advanced in silico analysis to identify novel therapeutic targets

Allison Rose Hanaford, Tenley C. Archer, Antoinette Price, Ulf Kahlert, Jarek Maciaczyk, Nikkhah Guido, Wlliam Kim, Tobias Ehrenberger, Paul Clemons, Vlado Dancik, Brinton Seashore-Ludlow, Vasanthi Viswanathan, Michelle Stewart, Matthew Rees, Alykahn Shamji, William Hahn, Stuart Schreiber, Ernest Fraenkel, Scott Pomeroy, Jill Mesirov, Pablo Tamayo, Charles G. Eberhart, Eric H. Raabe
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2476.
https://doi.org/10.1158/1538-7445.AM2016-2476
Published: 15 July 2016
View article titled, Abstract 2476: DiSCoVERing innovative therapies for rare tumors: Combining genetically accurate disease models with advanced in silico analysis to identify novel therapeutic targets