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Journal Articles

Abstract 931: Loss of CDKN2A in epithelioid hemangioendothelioma enhances tumorigenicity and imparts cellular immortality, thereby facilitating the generation of the first cell lines of this disease

Caleb Nathaniel Seavey, Shuang Ma, Andrea Hallett, Ajaybabu V. Pobbati, Kepeng Che, Shuo Li, Ashley Burtscher, Ryan Kanai, John M. Lamar, Brian P. Rubin

Cancer Res (2022) 82 (12_Supplement): 931.

https://doi.org/10.1158/1538-7445.AM2022-931

Published: 15 June 2022

View article titled, Abstract 931: Loss of CDKN2A in epithelioid hemangioendothelioma enhances tumorigenicity and imparts cellular immortality, thereby facilitating the generation of the first cell lines of this disease

Journal Articles

Abstract LB-151: Positively selected enhancer elements endow tumor cells with metastatic competence

James J. Morrow, Tyler E. Miller, Alina Saiakhova, Michael M. Lizardo, Cynthia F. Bartels, Ian Bayles, Stevephen Hung, Arnulfo Mendoza, Jay T. Myers, Frederick Allen, Analisa DiFeo, Brian P. Rubin, Alex Y. Huang, Paul S. Meltzer, Lee J. Helman, Chand Khanna, Peter C. Scacheri

Cancer Res (2016) 76 (14_Supplement): LB-151.

https://doi.org/10.1158/1538-7445.AM2016-LB-151

Published: 15 July 2016

View article titled, Abstract LB-151: Positively selected enhancer elements endow tumor cells with metastatic competence

Journal Articles

Abstract A08: IGF1R as a key target in high risk, metastatic medulloblastoma

Matthew N. Svalina, Ken Kikuchi, Jinu Abraham, Sangeet Lal, Monika A. Davare, Jennifer L. Peckham, Yoon-Jae Cho, Melanie Jackson, Daniel J. Guillaume, Nathan R. Selden, Darell D. Bigner, Kellie J. Nazemi, Sarah C. Green, Christopher L. Corless, Sakir Gultekin, Brian P. Rubin, Randall Woltjer, Charles Keller

Cancer Res (2015) 75 (23_Supplement): A08.

https://doi.org/10.1158/1538-7445.BRAIN15-A08

Published: 09 December 2015

View article titled, Abstract A08: IGF1R as a key target in high risk, metastatic medulloblastoma

Journal Articles

Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance

Nathalie Javidi-Sharifi, Elie Traer, Jacqueline Martinez, Anu Gupta, Takehiro Taguchi, Jennifer Dunlap, Michael C. Heinrich, Christopher L. Corless, Brian P. Rubin, Brian J. Druker, Jeffrey W. Tyner

Cancer Res (2015) 75 (5): 880–891.

https://doi.org/10.1158/0008-5472.CAN-14-0573

Published: 01 March 2015

View article titled, Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance

Includes: Supplementary data

Journal Articles

Abstract 1747: The Pax3:Foxo1a translocation product is a cell cycle-specific modifier of the alveolar rhabdomyosarcoma tumor phenotype.

Ken Kikuchi, Simone Hettmer, M. Imran Aslam, Joel E. Michalek, Wolfram Laub, Brian P. Rubin, Amy J. Wagers, Charles Keller

Cancer Res (2013) 73 (8_Supplement): 1747.

https://doi.org/10.1158/1538-7445.AM2013-1747

Published: 15 April 2013

View article titled, Abstract 1747: The Pax3:Foxo1a translocation product is a cell cycle-specific modifier of the alveolar rhabdomyosarcoma tumor phenotype.

Journal Articles

Abstract 1035: Crenolanib, a highly selective platelet-derived growth factor receptor α/β (PDGFRA/B) tyrosine kinase inhibitor, destabilizes ETV1 protein in KIT-mutant gastrointestinal stromal tumor (GIST) cells.

Yujiro Hayashi, Michael R. Bardsley, Yoshitaka Toyomasu, Takahiro Taguchi, Brian P. Rubin, Monique Carter, Abhijit Ramachandran, Tamas Ordog

Cancer Res (2013) 73 (8_Supplement): 1035.

https://doi.org/10.1158/1538-7445.AM2013-1035

Published: 15 April 2013

View article titled, Abstract 1035: Crenolanib, a highly selective platelet-derived growth factor receptor α/β (PDGFRA/B) tyrosine kinase inhibitor, destabilizes ETV1 protein in KIT-mutant gastrointestinal stromal tumor (GIST) cells.

Journal Articles

Abstract 5629: Arginine depravation therapy with arginine deiminase and autophagy inhibition is a novel therapeutic approach for the treatment of metastatic sarcomas that lack argininosuccinate synthetase expression

Dean Weich, Shunqiang Li, Tom Kitchens, Munir R. Tanas, Philip Boone, David Y. Chen, Douglas R. Adkins, John Bomalski, Brian P. Rubin, Brian A. Van Tine

Cancer Res (2012) 72 (8_Supplement): 5629.

https://doi.org/10.1158/1538-7445.AM2012-5629

Published: 15 April 2012

View article titled, Abstract 5629: Arginine depravation therapy with arginine deiminase and autophagy inhibition is a novel therapeutic approach for the treatment of metastatic sarcomas that lack argininosuccinate synthetase expression

Journal Articles

Abstract 1043: Role of protein kinase Cι in alveolar rhabdomyosarcoma

Ken Kikuchi, Anuradha Soundararajan, Lee Ann Zarzabal, Capella R. Weems, Laura D. Nelson, Sheila T. Hampton, Joel A. Michalek, Brian P. Rubin, Alan P. Fields, Charles Keller

Cancer Res (2011) 71 (8_Supplement): 1043.

https://doi.org/10.1158/1538-7445.AM2011-1043

Published: 15 April 2011

View article titled, Abstract 1043: Role of protein kinase Cι in alveolar rhabdomyosarcoma

Journal Articles

Proapoptotic Activity of Bortezomib in Gastrointestinal Stromal Tumor Cells

Sebastian Bauer, Joshua A. Parry, Thomas Mühlenberg, Matthew F. Brown, Danushka Seneviratne, Payel Chatterjee, Anna Chin, Brian P. Rubin, Shih-Fan Kuan, Jonathan A. Fletcher, Stefan Duensing, Anette Duensing

Cancer Res (2010) 70 (1): 150–159.

https://doi.org/10.1158/0008-5472.CAN-09-1449

Published: 04 January 2010

View article titled, Proapoptotic Activity of Bortezomib in Gastrointestinal Stromal Tumor Cells

Includes: Supplementary data

Journal Articles

Credentialing a Preclinical Mouse Model of Alveolar Rhabdomyosarcoma

Cancer Res (2009) 69 (7): 2902–2911.

https://doi.org/10.1158/0008-5472.CAN-08-3723

Published: 01 April 2009

View article titled, Credentialing a Preclinical Mouse Model of Alveolar Rhabdomyosarcoma

Includes: Supplementary data

Journal Articles

Genome-wide transcriptome analysis of nerve sheath tumors

Subbaya Subramanian, Robert B. West, Torsten O. Nielsen, Brian P. Rubin, Erinn Downs-Kelly, John R. Goldblum, Shirley Zhu, Kelli Montgomery, Pancras C.w Hogendoorn, Christopher L. Corless, Andre M. Oliveira, Christopher D.m Fletcher, Matt Van de Rijn

Cancer Res (2006) 66 (8_Supplement): 194.

Published: 15 April 2006

View article titled, Genome-wide transcriptome analysis of nerve sheath tumors

Journal Articles

A Knock-In Mouse Model of Gastrointestinal Stromal Tumor Harboring Kit K641E

Brian P. Rubin, Cristina R. Antonescu, James P. Scott-Browne, Melissa L. Comstock, Yansong Gu, Munir R. Tanas, Carol B. Ware, Jessica Woodell

Cancer Res (2005) 65 (15): 6631–6639.

https://doi.org/10.1158/0008-5472.CAN-05-0891

Published: 01 August 2005

View article titled, A Knock-In Mouse Model of Gastrointestinal Stromal Tumor Harboring Kit K641E

Journal Articles

A mouse model of gastrointestinal stromal tumor

Brian P. Rubin, Cristina R. Antonescu, Jay P. Scott-Browne, Melissa L. Comstock, Yansong Gu, Munir R. Tanas, Carol B. Ware, Jessica A. Woodell

Cancer Res (2005) 65 (9_Supplement): 462–463.

Published: 01 May 2005

View article titled, A mouse model of gastrointestinal stromal tumor

Journal Articles

Absence of BRAF and NRAS Mutations in Uveal Melanoma

Frank Cruz, III, Brian P. Rubin, David Wilson, Ajia Town, Arin Schroeder, Andrea Haley, Troy Bainbridge, Michael C. Heinrich, Christopher L. Corless

Cancer Res (2003) 63 (18): 5761–5766.

Published: 01 October 2003

View article titled, Absence of BRAF and NRAS Mutations in Uveal Melanoma

Journal Articles

KIT Activation Is a Ubiquitous Feature of Gastrointestinal Stromal Tumors

Brian P. Rubin, Samuel Singer, Connie Tsao, Anette Duensing, Marcia L. Lux, Robert Ruiz, Michele K. Hibbard, Chang-Jie Chen, Sheng Xiao, David A. Tuveson, George D. Demetri, Christopher D. M. Fletcher, Jonathan A. Fletcher

Cancer Res (2001) 61 (22): 8118–8121.

Published: 01 November 2001

View article titled, KIT Activation Is a Ubiquitous Feature of Gastrointestinal Stromal Tumors

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Abstract 931: Loss of CDKN2A in epithelioid hemangioendothelioma enhances tumorigenicity and imparts cellular immortality, thereby facilitating the generation of the first cell lines of this disease

Abstract LB-151: Positively selected enhancer elements endow tumor cells with metastatic competence

Abstract A08: IGF1R as a key target in high risk, metastatic medulloblastoma

Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance

Abstract 1747: The Pax3:Foxo1a translocation product is a cell cycle-specific modifier of the alveolar rhabdomyosarcoma tumor phenotype.

Abstract 1035: Crenolanib, a highly selective platelet-derived growth factor receptor α/β (PDGFRA/B) tyrosine kinase inhibitor, destabilizes ETV1 protein in KIT-mutant gastrointestinal stromal tumor (GIST) cells.

Abstract 5629: Arginine depravation therapy with arginine deiminase and autophagy inhibition is a novel therapeutic approach for the treatment of metastatic sarcomas that lack argininosuccinate synthetase expression

Abstract 1043: Role of protein kinase Cι in alveolar rhabdomyosarcoma

Proapoptotic Activity of Bortezomib in Gastrointestinal Stromal Tumor Cells

Credentialing a Preclinical Mouse Model of Alveolar Rhabdomyosarcoma

Genome-wide transcriptome analysis of nerve sheath tumors

A Knock-In Mouse Model of Gastrointestinal Stromal Tumor Harboring Kit K641E

A mouse model of gastrointestinal stromal tumor

Absence of BRAF and NRAS Mutations in Uveal Melanoma

KIT Activation Is a Ubiquitous Feature of Gastrointestinal Stromal Tumors

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