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Brian D. Lehmann
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Journal Articles

Abstract P5-09-01: Using isogenic model systems to determine mechanisms regulating mutant p53 protein stability in breast cancer cells

Lindsay Redman-Rivera, Hailing Jin, Brian D Lehmann, Jennifer A Pietenpol
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-09-01.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P5-09-01
Published: 15 February 2022
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Journal Articles

Abstract PD3-04: Multi-omics characterization of triple-negative breast cancer identifies therapeutic vulnerabilities and epigenetic immune suppression in the mesenchymal subtype

Brian D Lehmann, Antonio Colaprico, Tiago C Silva, Jianjiao Chen, Hanbing An, Yuguang Ban, Lily Wang, Jamaal L James, Justin Balko, Paula I Gonzalez-Ericsson, Melinda E Sanders, Bing Zhang, Jennifer A Pietenpol, Xi S Chen
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD3-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-PD3-04
Published: 15 February 2022
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Journal Articles

Abstract 2489: A functional genomics approach to determine mutant p53 gain-of-function mechanisms and phenotypes in tumorigenesis

Lindsay N. Redman-Rivera, Timothy M. Shaver, Hailing Jin, Johanna M. Schafer, Quanhu Sheng, Rachel A. Hongo, Kathryn E. Beckermann, Brian D. Lehmann, Ferrin C. Wheeler, Jennifer A. Pietenpol
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2489.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2489
Published: 01 July 2021
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Journal Articles

Abstract LB-301: Integrative genomic analysis identifies distinct mutational, epigenetic and immunological patterns among triple-negative breast cancer subtypes

Brian D. Lehmann, Antonio Colaprico, Jianjiao Chen, Lily Wang, Jennifer Pietenpol, Xi Chen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-301.
DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-301
Published: 01 July 2019
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Journal Articles

Abstract 531: Activity of the selective FGFR 1, 2 and 3 inhibitor INCB054828 in genetically-defined models of triple-negative breast cancer

Phillip C.C. Liu, Brian D. Lehmann, Bruce Ruggeri, Darlise DiMatteo, Johanna M. Schafer, Jin Lu, Sang Hyun Lee, Luping Lin, Timothy C. Burn, Melody Diamond, Alla Volgina, Liangxing Wu, Gregory Hollis, Reid Huber, Jennifer A. Pietenpol, Peggy Scherle
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 531.
DOI: https://doi.org/10.1158/1538-7445.AM2017-531
Published: 01 July 2017
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Journal Articles

Diverse, Biologically Relevant, and Targetable Gene Rearrangements in Triple-Negative Breast Cancer and Other Malignancies

Timothy M. Shaver, Brian D. Lehmann, J. Scott Beeler, Chung-I Li, Zhu Li, Hailing Jin, Thomas P. Stricker, Yu Shyr, Jennifer A. Pietenpol
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (16): 4850–4860.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-0058
Published: 14 August 2016
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Includes: Supplementary data
Journal Articles

Abstract 2068: Cyclooxygenase-1 gene expression contributes to multiple oncogenic pathways in high grade serous ovarian cancer

Andrew J. Wilson, Brian D. Lehmann, Jeanette Saskowski, MD Jashim Uddin, Cristina Daniel, Brenda C. Crews, Qi Liu, Shilin Zhao, Deok-Soo Son, Jennifer A. Pietenpol, Lawrence J. Marnett, Dineo Khabele
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2068.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2068
Published: 01 August 2015
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Journal Articles

Abstract P6-03-04: TGF-β receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer

Bojana Jovanovic, J Scott Beeler, Michael W Pickup, Anna Chytil, Agnieszka E Gorska, William J Ashby, Brian D Lehmann, Andries Zijlstra, Jennifer A Pietenpol, Harold L Moses
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-03-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS14-P6-03-04
Published: 01 May 2015
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Journal Articles

Abstract P6-08-04: Creation of a robust algorithm utilizing minimal gene sets normalized against a reference gene set to identify triple-negative breast cancer (TNBC) subtypes

Rob S Seitz, David R Hout, Stephan W Morris, Rebecca B Smith, Brian D Lehmann, Xi Chen, Jennifer A Pietenpol, Brian Z Ring
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-08-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS14-P6-08-04
Published: 01 May 2015
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Journal Articles

Abstract P3-04-03: PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors

Brian D Lehmann, Joshua A Bauer, Johanna M Schafer, Christopher S Pendleton, Luojia Tang, Kimberly C Johnson, Xi Chen, Justin M Balko, Henry Gomez, Carlos L Arteaga, Gordon B Mills, Melinda E Sanders, Jennifer A Pietenpol
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P3-04-03.
DOI: https://doi.org/10.1158/1538-7445.SABCS14-P3-04-03
Published: 01 May 2015
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Journal Articles

Abstract 4928: Cyclooxygenase-1 as a target for molecular imaging of high grade serous ovarian cancer

Andrew J. Wilson, Brian D. Lehmann, MD Jashim Ussin, Anna Elleman, Brenda Crews, Jeanette Saskowski, Jennifer Pietenpol, Lawrence J. Marnett, Dineo Khabele
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4928.
DOI: https://doi.org/10.1158/1538-7445.AM2014-4928
Published: 01 October 2014
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Journal Articles

Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer

Michael E. Feigin, S. Dipikaa Akshinthala, Kiyomi Araki, Avi Z. Rosenberg, Lakshmi B. Muthuswamy, Bernard Martin, Brian D. Lehmann, Hal K. Berman, Jennifer A. Pietenpol, Robert D. Cardiff, Senthil K. Muthuswamy
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (11): 3180–3194.
DOI: https://doi.org/10.1158/0008-5472.CAN-13-3415
Published: 29 May 2014
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Includes: Supplementary data
Journal Articles

Abstract 4698: Gene expression profiles of triple negative breast cancer epithelial and stromal cells are predictive of treatment response.

Bojana Jovanovic, Steven X. Chen, Brian D. Lehmann, Kimberly N. Johnson, Violeta Sanchez, Maria G. Kuba, Melinda E. Sanders, Ingrid A. Mayer, Harold L. Moses, Jennifer A. Pietenpol
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4698.
DOI: https://doi.org/10.1158/1538-7445.AM2013-4698
Published: 15 April 2013
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Journal Articles

Abstract 4411: γH2AX as a marker of genomic instability predicts cisplatin sensitivity in triple negative breast cancer cells

Brian D. Lehmann, Josh A. Bauer, Melinda E. Sanders, Bapsi A. Chakravarthy, Jennifer A. Pietenpol
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4411.
DOI: https://doi.org/10.1158/1538-7445.AM2011-4411
Published: 15 April 2011
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Journal Articles

Abstract 951: Loss-of-function screening identifies therapeutic targets for triple negative breast cancer (TNBC)

Joshua A. Bauer, Brian D. Lehmann, Gloria Glick, David Cortez, Ethan Lee, Jennifer A. Pietenpol
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 951.
DOI: https://doi.org/10.1158/1538-7445.AM2011-951
Published: 15 April 2011
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Journal Articles

Senescence-Associated Exosome Release from Human Prostate Cancer Cells

Brian D. Lehmann, Matthew S. Paine, Adam M. Brooks, James A. McCubrey, Randall H. Renegar, Rong Wang, David M. Terrian
Journal: Cancer Research
Cancer Res (2008) 68 (19): 7864–7871.
DOI: https://doi.org/10.1158/0008-5472.CAN-07-6538
Published: 30 September 2008
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