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Branimir I. Sikic
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Journal Articles

Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1

Ramin Dubey, Andres M. Lebensohn, Zahra Bahrami-Nejad, Caleb Marceau, Magali Champion, Olivier Gevaert, Branimir I. Sikic, Jan E. Carette, Rajat Rohatgi
Journal: Cancer Research
Cancer Res (2016) 76 (19): 5810–5821.
https://doi.org/10.1158/0008-5472.CAN-16-0716
Published: 02 October 2016
View articletitled, Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1
Open the PDF for Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1 in another window
Includes: Supplementary data
Journal Articles

Abstract 4001: The anti-CD47 antibody Hu5F9-G4 activates macrophages and inhibits ovarian cancer xenografts, alone and in combination with chemotherapy or immunotherapy

Rishil J. Kathawala, David C. Mundy, George E. Duran, Jens-Peter Volkmer, Kevin S. Kao, Yan C. Wang, Aditi Bellary, Irving L. Weissman, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4001.
https://doi.org/10.1158/1538-7445.AM2016-4001
Published: 15 July 2016
View articletitled, Abstract 4001: The anti-CD47 antibody Hu5F9-G4 activates macrophages and inhibits ovarian cancer xenografts, alone and in combination with chemotherapy or immunotherapy
Journal Articles

Abstract 2140: Cabazitaxel is more active than first generation taxanes in ABCB1(+) cell lines due to its higher intracellular accumulation and reduction in ATPase stimulation

George E. Duran, Dietmar Weitz, Dorothée Sémiond, Diego Gianolio, Sandrine Macé, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2140.
https://doi.org/10.1158/1538-7445.AM2016-2140
Published: 15 July 2016
View articletitled, Abstract 2140: Cabazitaxel is more active than first generation taxanes in ABCB1(+) cell lines due to its higher intracellular accumulation and reduction in ATPase stimulation
Journal Articles

Abstract 763: Resistance to cabazitaxel is associated with ABCB1/P-glycoprotein activation, alterations in β-tubulin content and dynamics, reduced BRCA1, and a mesenchymal phenotype in MCF-7 human breast cancer variants

George E. Duran, Yan C. Wang, E Brian Francisco, Francisco J. Martinez, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 763.
https://doi.org/10.1158/1538-7445.AM2014-763
Published: 01 October 2014
View articletitled, Abstract 763: Resistance to cabazitaxel is associated with ABCB1/P-glycoprotein activation, alterations in β-tubulin content and dynamics, reduced BRCA1, and a mesenchymal phenotype in MCF-7 human breast cancer variants
Journal Articles

Abstract 831: BAL101553 (prodrug of BAL27862): A unique microtubule destabilizer active against drug refractory breast cancers alone and in combination with trastuzumab

Felix Bachmann, Karin Burger, George E. Duran, Branimir I. Sikic, Heidi A. Lane
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 831.
https://doi.org/10.1158/1538-7445.AM2014-831
Published: 01 October 2014
View articletitled, Abstract 831: BAL101553 (prodrug of BAL27862): A unique microtubule destabilizer active against drug refractory breast cancers alone and in combination with trastuzumab
Journal Articles

Abstract 901: Overexpression of inhibitors of apoptosis (IAP) family members in human breast and ovarian cancer models of non-MDR1 taxane resistance.

George E. Duran, Anamaria Brozovic, Francisco J. Martinez, E Brian Francisco, Yan C. Wang, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 901.
https://doi.org/10.1158/1538-7445.AM2013-901
Published: 15 April 2013
View articletitled, Abstract 901: Overexpression of inhibitors of apoptosis (IAP) family members in human breast and ovarian cancer models of non-MDR1 taxane resistance.
Journal Articles

Abstract 1095: Comprehensive miRNA profiling of taxane-resistant human breast and ovarian cancer cell lines using the SmartChip real-time PCR system

George E. Duran, Cindy Y. Wang, E. Brian Francisco, Kee Wong, Nicole Robinson, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1095.
https://doi.org/10.1158/1538-7445.AM2012-1095
Published: 15 April 2012
View articletitled, Abstract 1095: Comprehensive miRNA profiling of taxane-resistant human breast and ovarian cancer cell lines using the SmartChip real-time PCR system
Journal Articles

Abstract 817: Enhancement of paclitaxel and carboplatin therapy by CCL2 blockade in ovarian cancers

Francois Moisan, Edgar B. Francisco, Anamaria Brozovic, George E. Duran, Yan C. Wang, Shobha Seetharam, Linda A. Snyder, Parul Doshi, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 817.
https://doi.org/10.1158/1538-7445.AM2012-817
Published: 15 April 2012
View articletitled, Abstract 817: Enhancement of paclitaxel and carboplatin therapy by CCL2 blockade in ovarian cancers
Journal Articles

Abstract LB-351: Comprehensive miRNA profiling of taxane-resistant human breast cancer variants using the SmartChip Real-Time PCR System

George E. Duran, Cindy Y. Wang, E. Brian Francisco, Kee Wong, Nicole Robinson, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-351.
https://doi.org/10.1158/1538-7445.AM2011-LB-351
Published: 15 April 2011
View articletitled, Abstract LB-351: Comprehensive miRNA profiling of taxane-resistant human breast cancer variants using the SmartChip Real-Time PCR System
Journal Articles

Abstract 1401: SYK promotes tumor progression in ovarian cancer cell lines

Aya Sultan, Cindy Y. Wang, George E. Duran, E. Brian Francisco, Jonathan S. Berek, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1401.
https://doi.org/10.1158/1538-7445.AM2011-1401
Published: 15 April 2011
View articletitled, Abstract 1401: SYK promotes tumor progression in ovarian cancer cell lines
Journal Articles

Abstract 1526: Epithelial mesenchymal transition (EMT) is associated with non-transporter resistance to taxanes in human ovarian cancer cell

Cindy Y. Wang, George E. Duran, E. Brian Francisco, Dejan Juric, Daniela Witten, Rob Tibshrani, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1526.
https://doi.org/10.1158/1538-7445.AM10-1526
Published: 15 April 2010
View articletitled, Abstract 1526: Epithelial mesenchymal transition (EMT) is associated with non-transporter resistance to taxanes in human ovarian cancer cell
Journal Articles

Abstract 4412: In vitro activity of the novel tubulin active agent BAL27862 in MDR1(+) and MDR1(−) human breast and ovarian cancer variants selected for resistance to taxanes

George E. Duran, Heidi Lane, Felix Bachmann, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4412.
https://doi.org/10.1158/1538-7445.AM10-4412
Published: 15 April 2010
View articletitled, Abstract 4412: In vitro activity of the novel tubulin active agent BAL27862 in MDR1(+) and MDR1(−) human breast and ovarian cancer variants selected for resistance to taxanes
Journal Articles

Abstract 3496: SYK inhibition results in increased sensitivity of OVCAR-3 cells to paclitaxel

Aya Sultan, Cindy Y. Wang, George E. Duran, E. Brian Francisco, Jonathan S. Berek, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3496.
https://doi.org/10.1158/1538-7445.AM10-3496
Published: 15 April 2010
View articletitled, Abstract 3496: SYK inhibition results in increased sensitivity of OVCAR-3 cells to paclitaxel
Journal Articles

Abstract 4672: Tumor dihydropyrimide dehydrogenase (DPYD) expression is associated with survival in patients with metastatic colorectal cancer treated with gefitinib, 5-fluorouracil, leucovorin, and oxaliplatin (IFOX)

Edgar B. Francisco, James T. Link, Meghan Ramsey, Andy H. Beck, Erich Schwartz, Robert Rouse, George A. Fisher, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4672.
https://doi.org/10.1158/1538-7445.AM10-4672
Published: 15 April 2010
View articletitled, Abstract 4672: Tumor dihydropyrimide dehydrogenase (DPYD) expression is associated with survival in patients with metastatic colorectal cancer treated with gefitinib, 5-fluorouracil, leucovorin, and oxaliplatin (IFOX)
Journal Articles

Gene copy number alterations and differential gene expression in the acquired resistance of ovarian cancer cells to taxanes

Dejan Juric, Yan C. Wang, Ron X. Yu, George E. Duran, E. Brian Francisco, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 296.
Published: 15 April 2006
View articletitled, Gene copy number alterations and differential gene expression in the acquired resistance of ovarian cancer cells to taxanes
Journal Articles

Gene-dosage effects in the human glioma transcriptome and their potential biological impact based on in silico interactome mapping

Markus Bredel, Dejan Juric, Claudia Bredel, Griffith R. Harsh, Hannes Vogel, Lawrence D. Recht, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 39.
Published: 15 April 2006
View articletitled, Gene-dosage effects in the human glioma transcriptome and their potential biological impact based on in silico interactome mapping
Journal Articles

TNFAIP3/A20 as a potential regulator of NF-κB-mediated resistance to O6-alkylating chemotherapy in glioblastoma multiforme

Markus Bredel, Claudia Bredel, Dejan Juric, George Duran, Ron X. Yu, Griffith R. Harsh, Hannes Vogel, Lawrence D. Recht, Adrienne C. Scheck, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1054.
Published: 15 April 2006
View articletitled, TNFAIP3/A20 as a potential regulator of NF-κB-mediated resistance to O6-alkylating chemotherapy in glioblastoma multiforme
Journal Articles

Impaired taxane- and epothilone-driven tubulin polymerization in a non-MDR1 taxane-resistant MCF-7 breast cancer variant with reduced MAP4 and elevated MAP Tau content

George E. Duran, Mary Ann Jordan, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 883.
Published: 15 April 2006
View articletitled, Impaired taxane- and epothilone-driven tubulin polymerization in a non-MDR1 taxane-resistant MCF-7 breast cancer variant with reduced MAP4 and elevated MAP Tau content
Journal Articles

Genetic and Epigenetic Modeling of the Origins of Multidrug-Resistant Cells in a Human Sarcoma Cell Line

Kevin G. Chen, Yan C. Wang, Marci E. Schaner, Brian Francisco, George E. Durán, Dejan Juric, Lyn M. Huff, Hesed Padilla-Nash, Thomas Ried, Tito Fojo, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2005) 65 (20): 9388–9397.
https://doi.org/10.1158/0008-5472.CAN-04-4133
Published: 17 October 2005
View articletitled, Genetic and Epigenetic Modeling of the Origins of Multidrug-Resistant Cells in a Human Sarcoma Cell Line
Open the PDF for Genetic and Epigenetic Modeling of the Origins of Multidrug-Resistant Cells in a Human Sarcoma Cell Line in another window
Includes: Supplementary data
Journal Articles

Functional Network Analysis Reveals Extended Gliomagenesis Pathway Maps and Three Novel MYC-Interacting Genes in Human Gliomas

Markus Bredel, Claudia Bredel, Dejan Juric, Griffith R. Harsh, Hannes Vogel, Lawrence D. Recht, Branimir I. Sikic
Journal: Cancer Research
Cancer Res (2005) 65 (19): 8679–8689.
https://doi.org/10.1158/0008-5472.CAN-05-1204
Published: 03 October 2005
View articletitled, Functional Network Analysis Reveals Extended Gliomagenesis Pathway Maps and Three Novel MYC-Interacting Genes in Human Gliomas
Open the PDF for Functional Network Analysis Reveals Extended Gliomagenesis Pathway Maps and Three Novel MYC-Interacting Genes in Human Gliomas in another window
Includes: Supplementary data