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Boris Pasche
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Journal Articles

Abstract 329: Proliferative inhibition of pancreatic cancer cells treated with pancreatic cancer - specific amplitude-modulated radiofrequency electromagnetic fields

Hugo Jimenez, Callum McGrath, Liyue Zhang, Grayson Barker, Allan M. Johansen, Janaka S. Liyanage, Mohammed N. Al Hallack, Anthony F. Shields, Wasif Saif, Husain Y. Khan, Amro Aboukameel, Hafiz Uddin, Sahar F. Bannoura, Ramzi M. Mohammad, Alexandre Barbault, Carl F. Blackman, Ravi K. Paluri, Asfar Azmi, Boris Pasche
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 329.
https://doi.org/10.1158/1538-7445.AM2025-329
Published: 21 April 2025
View articletitled, Abstract 329: Proliferative inhibition of pancreatic cancer cells treated with pancreatic cancer - specific amplitude-modulated radiofrequency electromagnetic fields
Journal Articles

Abstract 330: Treatment of fibrolamellar carcinoma with hepatocellular carcinoma -specific amplitude-modulated radiofrequency electromagnetic fields

Hugo Jimenez, Liyue Zhang, Grayson Barker, Callum McGrath, Allan M. Johansen, Janaka S. Liyanage, Mohammed N. Al Hallak, Anthony F. Shields, Wasif Saif, Husian Y. Khan, Amro aboukameel, Hafiz Uddin, Sahar F. Bannoura, Ramzi Mohammad, Sean Ronnekleiv-Kelly, Alexandre Barbault, Carl F. Blackman, Asfar Azmi, Boris Pasche
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 330.
https://doi.org/10.1158/1538-7445.AM2025-330
Published: 21 April 2025
View articletitled, Abstract 330: Treatment of fibrolamellar carcinoma with hepatocellular carcinoma -specific amplitude-modulated radiofrequency electromagnetic fields
Journal Articles

Abstract 5587: Regulator of chromosome condensation 1 (RCC1) as a novel therapeutic target in pancreatic ductal adenocarcinoma

Sahar F. Bannoura, Husain Y. Khan, Amro Aboukameel, Md Hafiz Uddin, Rund Nimri, Eliza Beal, Seongho Kim, Mohammed Najeeb Al Hallak, Bassel El-Rayes, Philip A. Philip, Boris Pasche, Ramzi Mohammad, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5587.
https://doi.org/10.1158/1538-7445.AM2024-5587
Published: 22 March 2024
View articletitled, Abstract 5587: Regulator of chromosome condensation 1 (RCC1) as a novel therapeutic target in pancreatic ductal adenocarcinoma
Journal Articles

Abstract 4574: Next generation nuclear export blocker KPT8602 synergizes with KRASG12D inhibitor MRTX1133 resulting in improved antitumor effects against pancreatic ductal adenocarcinoma

Husain Yar Khan, Amro Aboukameel, Md Hafiz Uddin, Sahar F. Bannoura, Khaled Keffri, Medha Jasti, Rachael Virga, Sarah Motorwala, Khalil Choucair, Tarik Hadid, Mohammad Najeeb Al-Hallak, Eliza Beal, Miguel Tobon, Rafic Beydoun, Greg Dyson, Steve Kim, Misako Nagasaka, Philip A. Philip, Basel El-Rayes, Herbert Chen, Anthony Shields, Ramzi Mohammad, Boris Pasche, Asfar Azmi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4574.
https://doi.org/10.1158/1538-7445.AM2024-4574
Published: 22 March 2024
View articletitled, Abstract 4574: Next generation nuclear export blocker KPT8602 synergizes with KRASG12D inhibitor MRTX1133 resulting in improved antitumor effects against pancreatic ductal adenocarcinoma
Journal Articles

Abstract 1939: NT219, a dual inhibitor of IRS1/2 and STAT3, suppresses cancer stem cell mediated resistance to KRASG12C and KRASG12D inhibitors in solid tumors

Hadas Reuveni, Mohammed Najeeb Al-Hallak, Sarah Motorwala, Eliza Beal, Steve Kim, Rafic Beydoun, Gergory Dyson, Bassel El-Rayes, Herbert Chen, Philip A. Philip, Anthony F. Shields, Boris Pasche, Katy Sigalov, Hava Ben-David, Daphna Miron, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1939.
https://doi.org/10.1158/1538-7445.AM2024-1939
Published: 22 March 2024
View articletitled, Abstract 1939: NT219, a dual inhibitor of IRS1/2 and STAT3, suppresses cancer stem cell mediated resistance to KRASG12C and KRASG12D inhibitors in solid tumors
Journal Articles

Abstract 806: TGFBR1*6A enhances breast cancer susceptibility and promote cell cycle transition

Kojo Agyemang, Michael Pennison, Minghui Wang, Allan Johansen, Hugo Jimenez, Carl Blackman, Ravi Singh, Ralph D'Agostino, Paul Grippo, Antonio Di Cristofano, Boris Pasche
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 806.
https://doi.org/10.1158/1538-7445.AM2021-806
Published: 01 July 2021
View articletitled, Abstract 806: TGFBR1*6A enhances breast cancer susceptibility and promote cell cycle transition
Journal Articles

Abstract 1394: Diagnosis of thyroid cancer using deep convolutional neural network models applied to sonographic images from clinical ultrasound exams

Xiangchun Li, Sheng Zhang, Qiang Zhang, Xi Wei, Yi Pan, Jing Zhao, Xiaojie Xin, Xiaoqing Wang, Fan Yang, Jianxin Li, Meng Yang, Qinghua Wang, Xiangqian Zheng, Yanhui Zhao, Lun Zhang, Xudong Wang, Zhimin Zheng, Christopher T. Whitlow, Metin N. Gurcan, Boris Pasche, Ming Gao, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1394.
https://doi.org/10.1158/1538-7445.AM2019-1394
Published: 01 July 2019
View articletitled, Abstract 1394: Diagnosis of thyroid cancer using deep convolutional neural network models applied to sonographic images from clinical ultrasound exams
Journal Articles

Abstract 3391: Dissecting intratumoral cell-cell interactions in myeloid reprogramming by single cell RNA-seq

Qianqian Song, Gregory A. Hawkins, Leonard Wudel, Ping-Chieh Chou, Elizabeth Forbes, Ashok K. Pullikuth, Liang Liu, Guangxu Jin, Lou Craddock, Umit Topaloglu, Gregory Kucera, Stacey O’Neill, Edward A. Levine, Peiqing Sun, Kounosuke Watabe, Yong Lu, Martha A. Alexander-Miller, Boris Pasche, Lance D. Miller, Wei Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3391.
https://doi.org/10.1158/1538-7445.AM2019-3391
Published: 01 July 2019
View articletitled, Abstract 3391: Dissecting intratumoral cell-cell interactions in myeloid reprogramming by single cell RNA-seq
Journal Articles

Abstract 3138: SMARCA4 mutations in KRAS-mutant lung adenocarcinoma: A multi-cohort analysis

LIANG LIU, Tamjeed Ahmed, Willam Jeffrey Petty, Stefan Grant, Jimmy Ruiz, Thomas W. Lycan, Umit Topaloglu, Ping-Chieh Chou, Lance D. Miller, Gregory A. Hawkins, Martha A. Alexander-Miller, Stacey S. O’Neill, Bayard L. Powell, Ralph B. D’Agostino, Reginald F. Munden, Boris Pasche, Wei Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3138.
https://doi.org/10.1158/1538-7445.AM2019-3138
Published: 01 July 2019
View articletitled, Abstract 3138: SMARCA4 mutations in KRAS-mutant lung adenocarcinoma: A multi-cohort analysis
Journal Articles

Abstract 3481: Roles of tumor suppressor candidate 2 (TUSC2) in glioblastoma progression and gliomagenesis

Tadas K. Rimkus, Dongqin Zhu, Richard L. Carpenter, Ivy Paw, Austin Arrigo, Sherona Sirkisoon, Daniel Doheny, Noah Aguayo, Jingyun Lee, Guangxu Jin, Eric Spooner, Boris Pasche, Waldemar Debinski, Hui-Wen Lo
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3481.
https://doi.org/10.1158/1538-7445.AM2019-3481
Published: 01 July 2019
View articletitled, Abstract 3481: Roles of tumor suppressor candidate 2 (TUSC2) in glioblastoma progression and gliomagenesis
Journal Articles

Abstract 5207: Breast cancer-specific amplitude modulated radiofrequency electromagnetic fields (AM RF EMF) inhibits brain metastasis of breast cancer

Sambad Sharma, Hugo Jimenez, Fei Xing, Carl Blackman, Boris Pasche, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5207.
https://doi.org/10.1158/1538-7445.AM2017-5207
Published: 01 July 2017
View articletitled, Abstract 5207: Breast cancer-specific amplitude modulated radiofrequency electromagnetic fields (AM RF EMF) inhibits brain metastasis of breast cancer
Journal Articles

Abstract 2867: FDG-PET imaging as a potential biomarker of mitochondrial targeting by CPI-613, a novel inhibitor of mitochondrial metabolism

Kiran Solingapuram Sai, Zuzana Zachar, Frankis Almaguel, Shawn D. Stuart, Michael S. Dahan, Moises Guardado, Stephanie Rideout, Minghui Wang, Anirudh Sattiraju, Paul M. Bingham, Boris Pasche, Akiva Mintz
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2867.
https://doi.org/10.1158/1538-7445.AM2017-2867
Published: 01 July 2017
View articletitled, Abstract 2867: FDG-PET imaging as a potential biomarker of mitochondrial targeting by CPI-613, a novel inhibitor of mitochondrial metabolism
Journal Articles

Abstract 1839: TGFBR1*6A mouse model mimics human breast cancer development and progression

Michael James Pennison, Minghui Wang, Hugo Jimenez, Boris Pasche
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1839.
https://doi.org/10.1158/1538-7445.AM2017-1839
Published: 01 July 2017
View articletitled, Abstract 1839: TGFBR1*6A mouse model mimics human breast cancer development and progression
Journal Articles

Abstract 1214: The polymeric fluoropyrimidine F10 is effective towards cell and organoid models of 5-FU-resistant colorectal cancer

William H. Gmeiner, Anthony Dominijanni, Olcay Boyacioglu, Steven Forsyth, Aleks Skardal, Boris Pasche
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1214.
https://doi.org/10.1158/1538-7445.AM2017-1214
Published: 01 July 2017
View articletitled, Abstract 1214: The polymeric fluoropyrimidine F10 is effective towards cell and organoid models of 5-FU-resistant colorectal cancer
Journal Articles

Activation of the c-Met Pathway Mobilizes an Inflammatory Network in the Brain Microenvironment to Promote Brain Metastasis of Breast Cancer

Fei Xing, Yin Liu, Sambad Sharma, Kerui Wu, Michael D. Chan, Hui-Wen Lo, Richard L. Carpenter, Linda J. Metheny-Barlow, Xiaobo Zhou, Shadi A. Qasem, Boris Pasche, Kounosuke Watabe
Journal: Cancer Research
Cancer Res (2016) 76 (17): 4970–4980.
https://doi.org/10.1158/0008-5472.CAN-15-3541
Published: 31 August 2016
View articletitled, Activation of the c-Met Pathway Mobilizes an Inflammatory Network in the Brain Microenvironment to Promote Brain Metastasis of Breast Cancer
Open the PDF for Activation of the c-Met Pathway Mobilizes an Inflammatory Network in the Brain Microenvironment to Promote Brain Metastasis of Breast Cancer in another window
Includes: Supplementary data
Journal Articles

TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis

Daniel R. Principe, Brian DeCant, Emman Mascariñas, Elizabeth A. Wayne, Andrew M. Diaz, Naomi Akagi, Rosa Hwang, Boris Pasche, David W. Dawson, Deyu Fang, David J. Bentrem, Hidayatullah G. Munshi, Barbara Jung, Paul J. Grippo
Journal: Cancer Research
Cancer Res (2016) 76 (9): 2525–2539.
https://doi.org/10.1158/0008-5472.CAN-15-1293
Published: 01 May 2016
View articletitled, TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis
Open the PDF for TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 4856: Association between breast cancer and constitutively decreased TGFBR1 signaling.

John C. Henegan, Lakisha Moore-Smith, Nengjun Yi, Kui Zhang, Habibul Ahsan, Alice S. Whittemore, Boris Pasche, BCFR Co-Investigators
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4856.
https://doi.org/10.1158/1538-7445.AM2013-4856
Published: 15 April 2013
View articletitled, Abstract 4856: Association between breast cancer and constitutively decreased TGFBR1 signaling.
Journal Articles

Abstract 5612: Cancer cell proliferation is inhibited by specific modulation frequencies.

Hugo Jimenez, Jacquelyn W. Zimmerman, Michael J. Pennison, Ivan Brezovich, Nengjun Yi, Celeste T. Yang, Ryne Ramaker, Devin Absher, Richard M. Myers, Niels Kuster, Frederico P. Costa, Alexandre Barbault, Boris Pasche
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5612.
https://doi.org/10.1158/1538-7445.AM2013-5612
Published: 15 April 2013
View articletitled, Abstract 5612: Cancer cell proliferation is inhibited by specific modulation frequencies.
Journal Articles

Abstract 916A: Cancer cell proliferation is inhibited by specific modulation frequencies

Jacquelyn W. Zimmerman, Michael J. Pennison, Ivan Brezovich, Nengjun Yi, Celeste T. Yang, Ryne Ramaker, Devin Absher, Richard M. Myers, Niels Kuster, Frederico P. Costa, Alexandre Barbault, Boris Pasche
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 916A.
https://doi.org/10.1158/1538-7445.AM2012-916A
Published: 15 April 2012
View articletitled, Abstract 916A: Cancer cell proliferation is inhibited by specific modulation frequencies
Journal Articles

Abstract 4853: Constitutively decreased TGF-β signaling and risk for colorectal cancer

Michael J. Pennison, Naresh Bellam, Jacquelyn Zimmerman, Qinghua Zeng, Maureen Sadim, Virginia Kaklamani, Nengjun Li, Kui Zhang, Daniel O. Stram, Boris Pasche
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4853.
https://doi.org/10.1158/1538-7445.AM2012-4853
Published: 15 April 2012
View articletitled, Abstract 4853: Constitutively decreased TGF-β signaling and risk for colorectal cancer